Immunoregulatory properties of growth hormone and prolactin
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References (272)
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Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma.
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Prolactin-Like Immunoreactivity: Localization in Nerve Terminals of Rat Hypothalamus
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Requirement of Nuclear Prolactin for Interleukin-2—Stimulated Proliferation of T Lymphocytes
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Receptor-Mediated Mitogenic Action of Prolactin in a Rat Lymphoma Cell Line*
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Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen.
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Intrinsic Pituitary Interleukin-1β Is Induced by Bacterial Lipopolysaccharide**
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Growth hormone and metabolism
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Neuroendocrine Control of Thymic Hormonal Production. I. Prolactin Stimulatesin Vivoandin Vitrothe Production of Thymulin by Human and Murine Thymic Epithelial Cells
1989 • 140 citations
Expression of prolactin and its receptor in human lymphoid cells
1992 • 140 citations
Concanavalin A-stimulated murine splenocytes produce a factor with prolactin-like bioactivity and immunoreactivity
1987 • 139 citations
Effect of Progestin, Antiprogestin, and Relaxin on the Accumulation of Prolactin and Insulin-Like Growth Factor-Binding Protein-1 Messenger Ribonucleic Acid in Human Endometrial Stromal Cells1
1992 • 137 citations
A novel role of growth hormone and insulin-like growth factor-I. Priming neutrophils for superoxide anion secretion.
1991 • 135 citations
A Human B-Lymphoblastoid Cell Line Produces Prolactin*
1988 • 134 citations
Anterior pituitary hormone control by interleukin 2.
1991 • 134 citations
The rat prolactin gene is expressed in brain tissue: detection of normal and alternatively spliced prolactin messenger RNA.
1992 • 133 citations
Specific Growth Hormone Receptors on Human Peripheral Mononuclear Cells: Reexpression, Identification, and Characterization
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Intracellular Calcium Concentration and Growth Hormone Secretion in Individual Somatotropes: Effects of Growth Hormone-Releasing Factor and Somatostatin*
1988 • 132 citations
The pituitary gland is required for protection against lethal effects of Salmonella typhimurium.
1991 • 130 citations
Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor.
1992 • 128 citations
Central action of interleukin‐1 in altering the release of tsh, growth hormone, and prolactin in the male rat
1987 • 126 citations
Receptor-mediated nuclear translocation of growth hormone.
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Growth Hormone Stimulates Sequential Induction of c-myc and Insulin-Like Growth Factor I Expressionin Vivo*
1987 • 121 citations
Immunology of the Nervous System
1998 • 121 citations
The influence of pituitary hormones on adjuvant arthritis
1984 • 120 citations
Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma
1994 • 120 citations
Cachectin alters anterior pituitary hormone release by a direct action in vitro.
1989 • 119 citations
HUMAN PITUITARY PROLACTIN (hPRL): THE ENTIRE LINEAR AMINO ACID SEQUENCE
1977 • 119 citations
Role of growth hormone in regulating T‐Dependent immune events in aged, nude, and transgenic rodents
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The sheep growth hormone receptor: Molecular cloning and ontogeny of mRNA expression in the liver
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Hormones and the immunological capacity. 3. The immunodeficiency disease of the hypopituitary Snell-Bagg dwarf mouse.
1971 • 115 citations
Stimulation of in vivo antibody production and concanavalin-A-induced mouse spleen cell mitogenesis by prolactin
1987 • 115 citations
The role of prolactin in autoimmune demyelination: Suppression of experimental allergic encephalomyelitis by bromocriptine
1991 • 113 citations
The Distal Enhancer Region of the Rat Prolactin Gene Contains Elements Conferring Response to Multiple Hormones
1989 • 111 citations
An inducible nuclear factor binds to a growth hormone-regulated gene.
1990 • 109 citations
Modulatory effect of prolactin on the resting and mitogen-induced activity of T, B, and NK lymphocytes
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Relationship between Thymus and Hypophysis
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Cellular localization of the growth hormone binding protein in the rat.
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Neuroendocrine control of growth hormone secretion in humans
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Growth hormone stimulation of normal and leukemic human T-lymphocyte proliferation in vitro
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The effect of growth hormone and insulin upon MLC responses and the generation of cytotoxic lymphocytes.
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Hormones and immunologic capacity. I. Effect of heterologous anti-growth hormone (ASTH) antiserum on thymus and peripheral lymphatic tissue in mice. Induction of a wasting syndrome.
1968 • 101 citations
Immunoreactive growth hormone (GH) secretion by human lymphocytes: Augmented release by exogenous GH
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Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment.
1994 • 99 citations
Characterization of Immunoreactive Insulin-Like Growth Factor-I from Leukocytes and Its Regulation by Growth Hormone*
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Anthropometric, metabolic, and immunological effects of recombinant human growth hormone in AIDS and AIDS-related complex.
1993 • 98 citations
Evidence that somatostatin is localized and synthesized in lymphoid organs.
1991 • 97 citations
Hypophysectomy Inhibits the Synthesis of Tumor Necrosis Factor α by Rat Macrophages: Partial Restoration by Exogenous Growth Hormone or Interferon γ*
1991 • 94 citations
Human thymocytes express a prolactin-like messenger ribonucleic acid and synthesize bioactive prolactin-like proteins.
1992 • 94 citations
Expression and function of insulin-like growth factor receptors on anti-CD3-activated human T lymphocytes.
1992 • 92 citations
Exogenous growth hormone treatment alters body composition and increases natural killer cell activity in women with impaired endogenous growth hormone secretion
1987 • 91 citations
Human growth hormone promotes engraftment of murine or human T cells in severe combined immunodeficient mice.
1992 • 91 citations
Effects of hormones on development and function of lymphoid tissues. Synergistic action of thyroxin and somatotropic hormone in pituitary dwarf mice.
1969 • 89 citations
Rapid release of multiple hormones from rat pituitaries perifused with recombinant interleukin-1
1989 • 89 citations
Distribution of Immunoreactive Prolactin in the Male and Female Rat Brain: Effects of Hypophysectomy and Intraventricular Administration of Colchicine
1988 • 88 citations
Induction by Cytokines of the Pattern of Pituitary Hormone Secretion in Infection
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Genomic organization of rat prolactin and growth hormone genes.
1980 • 84 citations
Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo
1992 • 84 citations
The production of growth hormone by subpopulations of rat mononuclear leukocytes
1991 • 83 citations
An Antisense Oligodeoxynucleotide to Growth Hormone Messenger Ribonucleic Acid Inhibits Lymphocyte Proliferation*
1991 • 83 citations
Ontogeny and evolution of prolactin's functions.
1980 • 82 citations
Prolactin (PRL) mRNA from human decidua differs from pituitary PRL mRNA but resembles the IM-9-P3 lymphoblast PRL transcript
1989 • 81 citations
Growth hormone-binding proteins: state of the art
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[Hormones and immunity].
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Variants of the 5′-untranslated sequence of human growth hormone receptor mRNA
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Prolactin receptors on large granular lymphocytes: Dual regulation by cyclosporin A
1988 • 79 citations
Bromocriptine suppresses postpartum exacerbation of collagen‐induced arthritis
1988 • 79 citations
Growth hormone releasing hormone receptors on thymocytes and splenocytes from rats
1991 • 78 citations
Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony-stimulating factor receptor.
1993 • 77 citations
Suppression of immune function in growth hormone-deficient children during treatment with human growth hormone
1986 • 77 citations
Growth hormone induces expression of c-jun and jun B oncogenes and employs a protein kinase C signal transduction pathway for the induction of c-fos oncogene expression
1991 • 75 citations
Thymus, peripheral lymphoid tissues and immunological responsiveness of the pituitary dwarf mouse
1967 • 74 citations
Cytokine Modulation of Pituitary Hormone Secretiona
1990 • 74 citations
Expression of the rat growth hormone-releasing hormone gene in placenta is directed by an alternative promoter.
1991 • 74 citations
Interleukin-2 Driven Nuclear Translocation of Prolactin in Cloned T-Lymphocytes*
1990 • 73 citations
Differential effects of proclatic upon activation and differentiation of human B lymphocytes
1993 • 73 citations
Prolactin isoform 2 as an autocrine growth factor for GH3 cells.
1992 • 72 citations
Interdependence of thymic and neuroendocrine functions in ontogeny.
1976 • 72 citations
Prolactin stimulation of ornithine decarboxylase and mitogenesis in Nb2 node lymphoma cells: The role of protein kinase C and calcium mobilization
1986 • 71 citations
STUDIES ON PITUITARY LACTOGENIC HORMONE. THE PRIMARY STRUCTURE OF THE PORCINE HORMONE*
1976 • 70 citations
Growth hormone secretion by human peripheral blood mononuclear cells detected by an enzyme-linked immunoplaque assay.
1993 • 68 citations
The expression of insulin-like growth factors and their binding proteins in normal human lymphocytes
1993 • 67 citations
Lymphocyte subset distribution and natural killer activity in growth hormone deficiency before and during short-term treatment with growth hormone releasing hormone
1988 • 67 citations
Altered release of growth hormone and thyrotropin induced by endotoxin in the rat
1982 • 67 citations
Growth hormone activates phospholipase C in proximal tubular basolateral membranes from canine kidney.
1989 • 65 citations
Enhanced Yields of Gamma Interferon in Prolactin Treated Human Peripheral Blood Mononuclear Cells
1994 • 65 citations
Growth Hormone What is it and what does it do?
1992 • 63 citations
Hormones and Immunologic Capacity
1968 • 63 citations
Psychoneuroimmunology
1992 • 63 citations
Induction of Pituitary Sensitivity to Interleukin-1: A New Function for Corticotropin-Releasing Hormone
1994 • 62 citations
Prolactin receptor gene expression in lymphoid cells
1991 • 61 citations
Prolactin and autoimmune disease
1993 • 60 citations
Immunoreactive growth hormone-releasing hormone in rat leukocytes
1990 • 59 citations
Insulin-Like Growth Factor Secretion by Human B-Lymphocytes: A Comparison of Cells from Normal and Pygmy Subjects*
1989 • 58 citations
The rat prolactin gene is expressed in brain tissue: detection of normal and alternatively spliced prolactin messenger RNA
1992 • 57 citations
Modulation of lymphoproliferation by human growth hormone
1983 • 56 citations
Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine
1992 • 56 citations
Identification by analytical flow cytometry of prolactin receptors on immunocompetent cell populations in the mouse.
1993 • 55 citations
Immunological Findings in Growth Hormone-Treated Patients
1993 • 55 citations
Detection of growth hormone-producing cells in human thymus by immunohistochemistry and non-radioactive in situ hybridization.
1994 • 55 citations
Humoral and Cell-Mediated Immunity in Growth Hormone-Deficient Children: Effect of Therapy with Human Growth Hormone
1985 • 54 citations
Pituitary epithelial cell implants reverse the accumulation of CD4-CD8- lymphocytes in thymus glands of aged rats.
1992 • 52 citations
Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine
1992 • 49 citations
Regulation of Prolactin Secretion in the Human BLymphoblastoid Cell Line IM-9-P3 by Dexamethasone but not Other Regulators of Pituitary Prolactin Secretion*
1989 • 48 citations
The primary structure of bovine prolactin
1974 • 48 citations
Biochemical response of lymphoma cells to mitogenic stimulation by prolactin
1982 • 47 citations
Staphylococcus aureus protein A induces the production of interferon-alpha in human lymphocytes and interferon-alpha/beta in mouse spleen cells.
1983 • 47 citations
Prolactin variants
1992 • 46 citations
Human thymocytes express a prolactin-like messenger ribonucleic acid and synthesize bioactive prolactin-like proteins
1992 • 46 citations
Prolactin and Immune Function
1991 • 44 citations
Expression of short and long forms of prolactin receptor in murine lymphoid tissues
1994 • 44 citations
Bromocriptine Microcapsules Inhibit Ornithine Decarboxylase Activity Induced by Freund's Complete Adjuvant in Lymphoid Tissues of Male Rats
1989 • 44 citations
Recombinant human growth hormone promotes human lymphocyte engraftment in immunodeficient mice and results in an increased incidence of human Epstein Barr virus-induced B-cell lymphoma
1992 • 44 citations
In vitro and in vivo effect of growth hormone on cytotoxic activity
1990 • 43 citations
The production of growth hormone and insulin-like growth factor-I by the same subpopulation of rat mononuclear leukocytes
1992 • 43 citations
Neuroendocrine Peptide Hormone Regulation of Immunity
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Tumorigenesis in Strain DW/J Mice and Induction by Prolactin of the Group-Specific Antigen of Endogenous C-Type RNA Tumor Virus<xref ref-type="fn" rid="FN2">2</xref>
1972 • 42 citations
Prolactin as an immunoregulatory hormone in mammals and birds
1992 • 42 citations
Evidence for a Role of Protein Kinase C in the Stimulation of Lipolysis by Growth Hormone and Isoproterenol*
1990 • 42 citations
Growth hormone (GH) receptor and GH-binding protein messenger ribonucleic acids with alternative 5'-untranslated regions are differentially expressed in mouse liver and placenta.
1995 • 42 citations
Interferon regulatory factor-1 is inducible by prolactin, interleukin-2 and concanavalin A in T cells
1992 • 41 citations
Effects of human growth hormone on immune functions: In vitro studies on cells of normal and growth hormone-deficient children
1987 • 41 citations
Detection of Growth Hormone and Growth Hormone-Releasing Hormone-Related Messenger RNA in Rat Leukocytes by the Polymerase Chain Reaction
1991 • 41 citations
Influence of Prolactin and Growth Hormone on the Activation of Dwarf Mouse Lymphocytes In Vivo
1993 • 40 citations
Complete amino acid sequence of mouse prolactin
1984 • 40 citations
Prolactin and prolactin secretagogues reverse immunosuppression in mice treated with cysteamine, glucocorticoids, or cyclosporin-A
1992 • 40 citations
An alternatively spliced form of Pit-1 represses prolactin gene expression.
1994 • 40 citations
A limited cytoplasmic region of the prolactin receptor critical for signal transduction
1994 • 39 citations
Neuroimmunoendocrinology
1992 • 38 citations
Hypothalamic action of cachectin to alter pituitary hormone release
1989 • 38 citations
Growth Hormone Inhibits Tumor Metastasis
1991 • 38 citations
A placenta-specific 5 ' non-coding exon of human prolactin
1991 • 37 citations
Human growth hormone : progress and challenges
1988 • 37 citations
Growth hormone secretion by human peripheral blood mononuclear cells detected by an enzyme-linked immunoplaque assay
1993 • 37 citations
Long-term assessment of patients with macroprolactinemia
1988 • 37 citations
Prolactin isoform 2 as an autocrine growth factor for GH3 cells
1992 • 36 citations
Cloning and Nucleotide Sequencing of Rat Lymphocyte Growth Hormone cDNA
1995 • 36 citations
Protein Secretion by Mesometrial and Antimesometrial Rat Decidual Tissue: Evidence for Differential Gene Expression*
1989 • 35 citations
Freund's complete adjuvant induces ornithine decarboxylase activity in the central nervous system of male rats and triggers the release of pituitary hormones
1990 • 35 citations
Somatolactogens, Somatomedins, and Immunity
1993 • 35 citations
Age dependency of the primary immune response in the hereditary pituitary dwarf and normal snell-bagg mouse
1967 • 34 citations
Prolactin and the neuroimmune network
1991 • 33 citations
Effects of Hypophysectomy on Immune Function
1991 • 33 citations
Immune functions in children treated with biosynthetic growth hormone
1989 • 33 citations
Expression of immunoreactive growth hormone in leukocytes in vivo
1991 • 33 citations
Immunoreactive Growth Hormone Production by Cultured Lymphocytesa
1992 • 32 citations
Prolactin‐Mediated Regulation of Gene Transcription in Lymphocytesa
1990 • 32 citations
Growth hormone expression in human Burkitt lymphoma serum-free Ramos cell line.
1993 • 31 citations
Cellular localization of the growth hormone binding protein in the rat
1992 • 30 citations
Nuclear co-localization of prolactin and the prolactin receptor in rat Nb2 node lymphoma cells.
1993 • 30 citations
Immunoreactive growth hormone production by human lymphocyte cell lines
1992 • 30 citations
Growth hormone (GH) secretion from human lymphocytes is up-regulated by GH, but not affected by insulin-like growth factor-I.
1993 • 30 citations
Pituitary epithelial cell implants reverse the accumulation of CD4-CD8- lymphocytes in thymus glands of aged rats
1992 • 29 citations
The indirect participation of growth hormone in the thymocyte proliferation system.
1994 • 29 citations
Effect of the Administration of Growth-Hormone-Producing Lymphocytes on Weight Gain and Immune Function in Dwarf Mice
1994 • 29 citations
Identification by analytical flow cytometry of prolactin receptors on immunocompetent cell populations in the mouse
1993 • 29 citations
Modulation of Prolactin-Stimulated Nb2Lymphoma Cell Mitogenesis by Cholera Toxin and Pertussis Toxin
1988 • 28 citations
Immunological studies in patients with isolated growth hormone deficiency.
1983 • 28 citations
In vivo growth hormone gene expression in neonatal rat thymus and bone marrow
1994 • 28 citations
Evidence for immunomodulatory properties of prolactin in selected in vitro and in vivo situations
1991 • 26 citations
Inhibition of recombinant human growth hormone-induced and prolactin-induced activation of neutrophils by octreotide
1993 • 24 citations
Effects of growth hormone on the expression of c-myc and c-fos during early stages of sex-differentiated rat liver carcinogenesis in the resistant hepatocyte model
1989 • 24 citations
Effect of Biosynthetic Methionyl Growth Hormone (GH) Therapy on the Immune Function in GH-Deficient Children
1989 • 23 citations
Postreceptor signaling mechanisms for growth hormone
1994 • 23 citations
In vivo activation of circulating monocytes by exogenous growth hormone in man
1992 • 22 citations
New frontiers in the molecular mechanisms of growth hormone action
1994 • 22 citations
Autocrine interaction between prolactin and its receptor occurs intracellularly in the 235-1 mammotroph cell line.
1994 • 22 citations
Posttranscriptional regulation of the human prolactin gene in IM-9-P3 cells by retinoic acid.
1992 • 21 citations
Immunological and Endocrinological Response to Growth Hormone Therapy in Short Children
1988 • 21 citations
Growth hormone (GH) receptor and GH-binding protein messenger ribonucleic acids with alternative 5'-untranslated regions are differentially expressed in mouse liver and placenta
1995 • 20 citations
Growth Hormone and the Immune System
1999 • 20 citations
Prolactin receptor expression by lymphoid tissues in normal and immunized rats
1993 • 20 citations
1 Prolactin and growth hormone
1988 • 18 citations
Growth Hormone Inhibits Activation of Phosphatidylinositol Phospholipase C by Insulin in ob/ob Mouse Adipose Tissue*
1990 • 18 citations
Production of Interleukin-1-Alpha and Interleukin-2 by Mononuclear Cells in Healthy Adults in Relation to Different Experimental Conditions and to the Presence of Growth Hormone
1990 • 18 citations
An alternatively spliced form of Pit-1 represses prolactin gene expression
1994 • 17 citations
Subcellular distribution of hypothalamic prolactin-like immunoreactivity
1987 • 17 citations
Growth hormone inhibits normal B-cell differentiation and neutrophils' chemotaxis in vitro
1994 • 16 citations
Production of Interleukin-1&alpha; and Interleukin-2 by Mononuclear Cells from Children with Growth Delay in Relation to the Degree of Growth Hormone Deficiency: Effects of Substitutive Treatment
1990 • 16 citations
Growth hormone expression in human Burkitt lymphoma serum-free Ramos cell line
1993 • 16 citations
Effect of Elevated Serum Prolactin Concentrations on Cytokine Production and Natural Killer Cell Activity
1992 • 16 citations
Regulation of growth hormone-releasing hormone gene expression and biosynthesis.
1989 • 15 citations
Growth hormone (GH) secretion from human lymphocytes is up-regulated by GH, but not affected by insulin-like growth factor-I
1993 • 15 citations
Phorbol ester stimulates prolactin release but reduces prolactin mRNA in the human B-lymphoblastoid cell line IM-9-P3
1989 • 13 citations
Nuclear co-localization of prolactin and the prolactin receptor in rat Nb2 node lymphoma cells
1993 • 13 citations
The effect of bromocriptine and cyclosporine on spontaneous diabetes in BB rats.
1988 • 12 citations
The Snell-dwarfmouse. II. Sulphate and thymidine incorporation in costal cartilage and somatomedin levels before and during growth hormone and thyroxine therapy.
1978 • 12 citations
Autocrine interaction between prolactin and its receptor occurs intracellularly in the 235-1 mammotroph cell line
1994 • 11 citations
Growth hormone induces the tyrosine phosphorylation and nuclear accumulation of components of the ISGF3 transcription factor complex
1994 • 10 citations
An inhibitor of ornithine decarboxylase in lactogen-deprived Nb2 node rat lymphoma cells
1986 • 9 citations
Mechanism of pokeweed mitogen inhibition of rhIL-4-induced human IgE synthesis
1992 • 9 citations
Posttranscriptional regulation of the human prolactin gene in IM-9-P3 cells by retinoic acid
1992 • 9 citations
THE SNELL-DWARFMOUSE II.
1978 • 9 citations
Neuroimmunoendocrinology (2nd edn)
1992 • 6 citations
GROWTH HORMONE AND LYMPHOCYTE TRANSFORMATION
1973 • 6 citations
The structure of a myelin basic protein-associated idiotope
1993 • 6 citations
Growth hormone increases phosphoinositide turnover in rat adipocytes that are sensitive to the insulin-like action of the hormone
1990 • 6 citations
Control of growth hormone secretion at the single cell level
1993 • 5 citations
Prolactin Stimulation of Nb 2 Node Lymphoma Cell Division Is Inhibited by Polyamine Biosynthesis Inhibitors
1985 • 3 citations