Evidence for a Role of Protein Kinase C in the Stimulation of Lipolysis by Growth Hormone and Isoproterenol*

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Adenosine 3‘,5‘-Phosphate in Biological Materials

1962 • 2,102 citations

The Metabolism of Isolated Fat Cells: I. Effects of Hormones on Glucose Metabolism and Lipolysis

1964 • 1,401 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Regulation of transmembrane signaling by receptor phosphorylation

1987 • 678 citations

Effect of Growth Hormone on Carbohydrate and Lipid Metabolism

1987 • 584 citations

Forskolin: its biological and chemical properties.

1986 • 566 citations

Effects of Lipolytic and Antilipolytic Substances on Adenosine 3′,5′-Monophosphate Levels in Isolated Fat Cells

1968 • 555 citations

Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes.

1983 • 406 citations

Effect of hormones on lipolysis and esterification of free fatty acids during incubation of adipose tissue in vitro

1963 • 314 citations

Protein kinase C — a family affair

1989 • 289 citations

Phorbol diesters promote β-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes

1984 • 238 citations

Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.

1984 • 233 citations

Regulation of adenylate cyclase by adenosine

1979 • 218 citations

Effects of Lipolytic and Antilipolytic Agents on Cyclic 3',5'-Adenosine Monophosphate in Fat Cells

1971 • 199 citations

Regulation of Hormone Receptors and Adenylyl Cyclases by Guanine Nucleotide Binding N Proteins

1985 • 159 citations

Growth hormone promoted tyrosyl phosphorylation of growth hormone receptors in murine 3T3-F442A fibroblasts and adipocytes

1988 • 109 citations

Interleukin 2 modulation of adenylate cyclase. Potential role of protein kinase C.

1986 • 93 citations

Phosphorylation of Highly Purified Growth Hormone Receptors by a Growth Hormone Receptor-associated Tyrosine Kinase

1989 • 89 citations

GTP-binding proteins as possible targets for protein kinase C action

1989 • 79 citations

Human fat cell lipolysis is primarily regulated by inhibitory modulators acting through distinct mechanisms.

1985 • 78 citations

Phorbol diester treatment promotes enhanced adenylate cyclase activity in frog erythrocytes

1986 • 76 citations

Permissive Effects of Hormones on Lipolysis¹

1970 • 67 citations

Sphingosine, an inhibitor of protein kinase C, suppresses the insulin-like effects of growth hormone in rat adipocytes.

1989 • 58 citations

Stimulation by Growth Hormone and Dexamethasone of Labeled Cyclic Adenosine 3',5'-Monophosphate Accumulation by White Fat Cells

1970 • 57 citations

The protein kinase C activator phorbol‐12‐myristate‐13‐acetate enhances cyclic AMP accumulation in pheochromocytoma cells

1986 • 54 citations

Effect of Dibutyryl-3′,5′-AMP, Theophylline and Norepinephrine on Lipolytic Action of Growth Hormone and Glucocorticoid in White Fat Cells

1968 • 54 citations

Studies on the role of RNA and protein synthesis in the lipolytic action of growth hormone in isolated fat cells

1967 • 54 citations

Effects of Growth Hormone on the Lipolytic Response of Adipose Tissue to Theophylline¹

1968 • 52 citations

Interconvertible enzymes in adipose tissue regulated by cyclic AMP-dependent protein kinase.

1976 • 51 citations

Role of kinase C in the insulin-like effects of human growth hormone in rat adipocytes

1987 • 50 citations

The role of cyclic AMP in activation of hormone-sensitive lipase of adipose tissue.

1972 • 49 citations

Promotion of lipolysis in rat adipocytes by pertussis toxin: reversal of endogenous inhibition.

1983 • 43 citations

Responses of Adipose Tissue to Sequential Lipolytic Stimulir¹²

1974 • 42 citations

Evaluation of Adenosine or Related Nucleosides as Physiological Regulators of Lipolysis in Adipose Tissue*

1982 • 41 citations

INHIBITION BY GLUCOCORTICOIDS OF PROSTAGLANDIN RELEASE FROM ADIPOSE TISSUE in vitro

1977 • 40 citations

Activation of protein kinase C modulates the adenylate cyclase effector system of B-lymphocytes

1989 • 38 citations

Inhibition of Prostaglandin Biosynthesis in Human Adipose Tissue by Glucocorticosteroids*

1983 • 23 citations

The involvement of RNA synthesis and cyclic AMP in the activation of fat cell lipolysis by growth hormone and glucocorticoids.

1970 • 22 citations

Different Growth Hormone-Receptor Interactions Mediate Insulin-Like and Lipolytic Responses of Rat Adipose Tissue*

1989 • 22 citations

Preparation and Biological Reactivity of Polyiodinated Human Growth Hormone*

1983 • 20 citations

Growth Hormone and Phosphorylase Activity in Adipose Tissue¹

1969 • 17 citations

Potentiation of prostaglandin E1-stimulated cAMP formation by 12-O-tetradecanoylphorbol-13-acetate in balb/C mouse 3T3 cells

1986 • 12 citations

Hormonal control of FAT cells adenylate cyclase

1976 • 10 citations

Effects of Hypophysectomy and Cell Isolation on the Transport of L-Arabinose by Adipocytes*

1985 • 10 citations