Growth hormone and metabolism

Actions of Insulin-Like Growth Factors

1985 • 1,141 citations

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro. 1956.

1990 • 1,075 citations

Hormone-fuel interrelationships during fasting.

1966 • 1,032 citations

Dual control of cell growth by somatomedins and platelet-derived growth factor.

1979 • 926 citations

Estimation of Somatomedin-C Levels in Normals and Patients with Pituitary Disease by Radioimmunoassay

1977 • 858 citations

Somatomedin-C Mediates Growth Hormone Negative Feedback by Effects on Both the Hypothalamus and the Pituitary

1981 • 829 citations

Primary structure of human insulin‐like growth factor II

1978 • 776 citations

On thein Vitroandin VivoActivity of a New Synthetic Hexapeptide that Acts on the Pituitary to Specifically Release Growth Hormone*

1984 • 652 citations

Hypoglycemia: A Potent Stimulus to Secretion of Growth Hormone

1963 • 649 citations

Insulin-like growth factor I stimulates growth in hypophysectomized rats

1982 • 605 citations

Studies of Insulin, Growth Hormone and Prolactin Binding: Tissue Distribution, Species Variation and Characterization

1974 • 592 citations

Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro

1964 • 540 citations

Growth Hormone Stimulates Longitudinal Bone Growth Directly

1982 • 524 citations

Human growth hormone DNA sequence and mRNA structure: possible alternative splicing

1981 • 464 citations

The Regulation of Growth Hormone Secretion

2015 • 440 citations

Secretion of human growth hormone: physiologic and experimental modification.

1963 • 435 citations

Effects of Growth Hormone on Insulin Action in Man: Mechanisms of Insulin Resistance, Impaired Suppression of Glucose Production, and Impaired Stimulation of Glucose Utilization

1982 • 434 citations

Dietary components that regulate serum somatomedin-C concentrations in humans.

1983 • 433 citations

A Specific Growth Hormone-Binding Protein in Human Plasma: Initial Characterization*

1986 • 424 citations

EFFECT OF GROWTH HORMONE ON PLASMA FATTY ACIDS*

1959 • 424 citations

Impaired Growth Hormone Responses to Growth Hormone–Releasing Factor in Obesity

1984 • 420 citations

ANTIBODY-SUPPRESSIBLE AND NONSUPPRESSIBLE INSULIN-LIKE ACTIVITIES IN HUMAN SERUM AND THEIR PHYSIOLOGIC SIGNIFICANCE. AN INSULIN ASSAY WITH ADIPOSE TISSUE OF INCREASED PRECISION AND SPECIFICITY*

1963 • 399 citations

Insulin‐Like Growth Factors I and II: Some Biological Actions and Receptor Binding Characteristics of Two Purified Constituents of Nonsuppressible Insulin‐Like Activity of Human Serum

1978 • 384 citations

The Effect of Growth Hormone on Glucose Metabolism and Insulin Secretion in Man*

1982 • 331 citations

The Human Growth Hormone Gene Family: Nucleotide Sequences Show Recent Divergence and Predict a New Polypeptide Hormone

1982 • 312 citations

Defective Glucose Counterregulation after Strict Glycemic Control of Insulin-Dependent Diabetes Mellitus

1987 • 312 citations

Evidence suggesting that the direct growth-promoting effect of growth hormone on cartilage in vivo is mediated by local production of somatomedin.

1986 • 310 citations

Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats.

1986 • 306 citations

Causes of death in the aged.

1950 • 296 citations

Insulin-like Growth Factors

1983 • 278 citations

Diurnal patterns of blood glucose, serum free fatty acids, insulin, glucagon and growth hormone in normals and juvenile diabetics

1970 • 277 citations

Glucose Counterregulation in Man

1981 • 268 citations

HUMAN PANCREATIC GROWTH-HORMONE-RELEASING FACTOR SELECTIVELY STIMULATES GROWTH-HORMONE SECRETION IN MAN

1983 • 263 citations

ACUTE INTERMITTENT PORPHYRIA

1970 • 257 citations

PATTERNS OF HORMONAL RELEASE AFTER GLUCOSE, PROTEIN, AND GLUCOSE PLUS PROTEIN

1966 • 254 citations

Somatomedins

1980 • 247 citations

VIBRIO PARAHÆMOLYTICUS

1974 • 235 citations

The “Dawn Phenomenon” — A Common Occurrence in Both Non-Insulin-Dependent and Insulin-Dependent Diabetes Mellitus

1984 • 231 citations

Insulin-Like Growth Factors in the Fed and Fasted States*

1982 • 228 citations

Plasma Growth Hormone Response to Intravenous Administration of Amino Acids

1965 • 226 citations

The Hormonal Control of Hepatic Gluconeogenesis

1970 • 221 citations

LABETALOL AND PLATELET FUNCTION IN PRE-ECLAMPSIA

1982 • 220 citations

Preparation and Properties of Growth Hormone from Human and Monkey Pituitary Glands

1956 • 219 citations

Pathogenesis of the Dawn Phenomenon in Patients with Insulin-Dependent Diabetes Mellitus

1985 • 213 citations

Abnormalities in carbohydrate tolerance associated with elevated plasma nonesterified fatty acids.

1965 • 211 citations

Arginine-Initiated Release of Human Growth Hormone

1969 • 209 citations

The Effects of Insulin and Growth Hormone on the Release of Somatomedin by the Isolated Rat Liver

1976 • 209 citations

Importance of Raised Growth Hormone Levels in Mediating the Metabolic Derangements of Diabetes

1984 • 207 citations

EFFECT OF ARGININE ON SERUM-LEVELS OF HUMAN GROWTH-HORMONE

1965 • 207 citations

The Insulin-Like Growth Factors (IGF) of Human Serum: Chemical and Biological Characterization and Aspects of Their Possible Physiological Role

1981 • 207 citations

ISOLATION AND PROPERTIES OF THE ANTERIOR HYPOPHYSEAL GROWTH HORMONE

1945 • 205 citations

PLASMA INSULIN AND GROWTH HORMONE LEVELS IN OBESITY AND DIABETES

1965 • 204 citations

DIABETES, DIABETIC ANGIOPATHY, AND GROWTH HORMONE

1970 • 204 citations

PERMANENT EXPERIMENTAL DIABETES PRODUCED BY PITUITARY (ANTERIOR LOBE) INJECTIONS

1937 • 204 citations

Human Growth Hormone: A Complex of Proteins

1980 • 201 citations

Effects of physiologic levels of glucagon and growth hormone on human carbohydrate and lipid metabolism. Studies involving administration of exogenous hormone during suppression of endogenous hormone secretion with somatostatin.

1976 • 199 citations

Physiological roles of somatocrinin and somatostatin in the regulation of growth hormone secretion

1982 • 198 citations

Effect of Diabetes and its Control on Insulin-like Growth Factors in the Young Subject with Type I Diabetes

1984 • 189 citations

Changes of Carbohydrate Tolerance in Acromegaly with Progress of the Disease and in Response to Treatment

1967 • 185 citations

Transmission of conformational change in insulin

1983 • 183 citations

Comparison of in vivo effects of insulin-like growth factors I and II and of growth hormone in hypophysectomized rats

1985 • 180 citations

The Effect of Free Fatty Acids on Growth Hormone(GH)-Releasing Hormone-Mediated GH Secretion in Man*

1985 • 179 citations

OVARIAN FUNCTION AND BODY TEMPERATURE

1945 • 177 citations

Intensive Insulin Therapy Reduces Counterregulatory Hormone Responses to Hypoglycemia in Patients with Type I Diabetes

1985 • 175 citations

Physiological Concentrations of Growth Hormone Exert Insulin-Like and Insulin Antagonistic Effects on Both Hepatic and Extrahepatic Tissues in Man*

1981 • 173 citations

Inhibition of the Action of Nonsuppressible Insulin-Like Activity on Isolated Rat Fat Cells by Binding to its Carrier Protein

1979 • 170 citations

ROLES OF INSULIN AND GROWTH HORMONE, BASED ON STUDIES ON FOREARM METABOLISM IN MAN

1963 • 168 citations

Effects of Growth Hormone, Prolactin, and Placental Lactogen on Insulin Content and Release, and Deoxyribonucleic Acid Synthesis in Cultured Pancreatic Islets

1982 • 165 citations

Metabolic Effects of Human and Monkey Growth Hormone in Man

1957 • 164 citations

Abnormal serum growth hormone response to exercise in juvenile diabetics

1970 • 164 citations

Effects of Growth Hormone Excess and Deficiency on Hypothalamic Somatostatin Content and Release and on Tissue Somatostatin Distribution*

1981 • 164 citations

Genes for Growth Hormone, Chorionic Somatomammotropin, and Growth Hormone-Like Gene on Chromosome 17 in Humans

1980 • 158 citations

Both Human Pituitary Growth Hormone and Recombinant DNA-Derived Human Growth Hormone Cause Insulin Resistance at a Postreceptor Site*

1982 • 158 citations

The Isolation of Pituitary Growth Hormone

1944 • 157 citations

Evidence from the use of monoclonal antibody probes for structural heterogeneity of the growth hormone receptor

1985 • 148 citations

Growth Hormone Administration Conserves Lean Body Mass during Dietary Restriction in Obese Subjects*

1987 • 144 citations

RAPID EFFECTS OF GROWTH HORMONE ON AMINO ACID TRANSPORT AND PROTEIN SYNTHESIS^*

1968 • 140 citations

Purification and partial characterization of a nonprimate growth hormone receptor.

1979 • 140 citations

The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21→qter

1981 • 138 citations

ALGODYSTROPHY AFTER AORTIC BIFURCATION SURGERY

1984 • 137 citations

Effects of local administration of GH and IGF-1 on longitudinal bone growth in rats

1986 • 136 citations

Hypoglycemia Associated with Non-Islet-Cell Tumor and Insulin-like Growth Factors

1981 • 136 citations

The Hypophysis and Metabolism

1936 • 135 citations

Correlative studies of growth hormone and insulin plasma concentrations with metabolic abnormalities in acromegaly.

1965 • 133 citations

Human hypothalamic growth hormone releasing factor (GRF): Evidence for two forms identical to tumor derived GRF-44-NH2 and GRF-40

1983 • 133 citations

Studies on Growth Hormone Secretion in Protein-Calorie Malnutrition

1968 • 130 citations

Growth Hormone and Insulin Binding to Human Liver

1976 • 129 citations

Variants of Growth Hormone and Prolactin and their Posttranslational Modifications

1984 • 126 citations

GROWTH HORMONE AND THE METABOLISM OF CARBOHYDRATE AND LIPID IN ADIPOSE TISSUE^*

1968 • 124 citations

Measurement of Insulin-Like Growth Factor II by a Specific Radioreceptor Assay in Serum of Normal Individuals, Patients with Abnormal Growth Hormone Secretion, and Patients with Tumor-Associated Hypoglycemia*

1981 • 123 citations

Serum levels of insulin-like growth factor (IGF) and its carrier protein in various metabolic disorders

1980 • 122 citations

The Influence of Blood Glucose on the Plasma Concentration of Growth Hormone

1964 • 122 citations

Structural Variants of Human Growth Hormone: Biochemical, Genetic, and Clinical Aspects

1983 • 120 citations

Stimulation of Counterregulatory Hormonal Responses in Diabetic Man by a Fall in Glucose Concentration

1980 • 120 citations

The effect of administration of human growth hormone on the plasma growth hormone, cortisol, glucose, and free fatty acid response to insulin: evidence for growth hormone autoregulation in man

1971 • 118 citations

Effects of Insulin on Rat Anterior Pituitary Cells: Inhibition of Growth Hormone Secretion and mRNA Levels

1986 • 118 citations

GROWTH HORMONE AND KWASHIORKOR

1966 • 117 citations

Integrated Concentration of Growth Hormone in Juvenile-onset Diabetes

1980 • 117 citations

Insulin suppresses growth hormone secretion by rat pituitary cells.

1984 • 116 citations

GROWTH-HORMONE AND CORTISOL RESPONSES TO INSULIN INFUSION IN PATIENTS WITH DIABETES MELLITUS

1972 • 109 citations

2 Plasma forms of somatomedin and the binding protein phenomenon

1984 • 108 citations

STUDIES ON HUMAN GROWTH HORMONE. II. THE PHYSIOLOGICAL DISPOSITION AND METABOLIC FATE OF HUMAN GROWTH HORMONE IN MAN*

1962 • 107 citations

Effects of Insulin-Like Growth Factors on Adult Male Rat Pituitary Function in Tissue Culture*

1984 • 106 citations

The Effects of Growth Hormone (GH)-Releasing Peptides on GH Secretion in Perifused Pituitary Cells of Adult Male Rats*

1984 • 106 citations

National Health Service

1979 • 102 citations

PLASMA-INSULIN RESPONSE TO SUSTAINED HYPERGLYCÆMIA INDUCED BY GLUCOSE INFUSION IN HUMAN SUBJECTS

1963 • 101 citations

Rate of Glucose Fall Does Not Affect Counterregulatory Hormone Responses to Hypoglycemia in Normal and Diabetic Humans

1987 • 100 citations

The Growth-Promoting and Anti-Insulin Actions of Somatotropin

1966 • 100 citations

Acute Metabolic Effects of Human Growth Hormone

1974 • 99 citations

Studies of hyperlipidemia in the HGH-deficient state

1972 • 97 citations

EFFECT OF FOOD INTAKE ON GROWTH-HORMONE LEVEL

1963 • 95 citations

The Molecular Nature of Circulating Growth Hormone in Normal and Acromegalic Man: Evidence for a Principal and Minor Monomeric Forms*

1983 • 94 citations

THE EFFECT OF HUMAN GROWTH HORMONE IN MAN

1959 • 94 citations

NSILA-carrier protein abolishes the action of nonsuppressible insulin-like activity (NSILA-S) on perfused rat heart

1978 • 94 citations

Effects of Hypophysectomy on Amino Acid Metabolism and Gluconeogenesis in the Perfused Rat Liver

1973 • 92 citations

Relation of Purified Pituitary Growth Hormone and Insulin in Regulation of Nitrogen Balance

1951 • 91 citations

IN SEARCH OF THE SOMOGYI EFFECT

1980 • 90 citations

COMPARATIVE RAPIDITY OF RESPONSE OF HEIGHT, LIMB MUSCLE AND LIMB FAT TO TREATMENT WITH HUMAN GROWTH HORMONE IN PATIENTS WITH AND WITHOUT GROWTH HORMONE DEFICIENCY

1977 • 89 citations

Reactivity of Non-Primate Growth Hormones and Prolactins with Human Growth Hormone Receptors on Cultured Human Lymphocytes

1977 • 89 citations

HISTOLOGY OF DIABETES INDUCED IN DOGS BY INJECTION OF ANTERIOR-PITUITARY EXTRACTS

1938 • 87 citations

STUDIES IN ACROMEGALY

1929 • 87 citations

Insulin-like growth factors stimulate synthesis of nucleic acids and glycogen in cultured calvaria cells

1983 • 86 citations

Growth Hormone and Somatomedin in Insulin-Dependent Diabetes Mellitus*

1981 • 86 citations

Current Concepts of Somatomedin and Other Biologically Related Growth Factors

1976 • 85 citations

Glucose Counterregulation and Waning of Insulin in the Somogyi Phenomenon (Posthypoglycemic Hyperglycemia)

1984 • 85 citations

Distribution of Immunoreactive Growth Hormone-Releasing Hormone in the Human Brain and Intestine and Its Production by Tumors*

1984 • 83 citations

Effect of growth hormone on oral glucose tolerance and circulating metabolic fuels in man

1983 • 83 citations

Metabolic response to human growth hormone during prolonged starvation

1971 • 83 citations

In VitroStimulation of Leucine Incorporation Into Muscle and Cartilage Protein by a Serum Fraction with Sulfation Factor Activity: Differentiation of Elfects from Those of Growth Hormone and Insulin

1970 • 82 citations

Growth hormone in the regulation of hyperlipidemia

1982 • 81 citations

THE EFFECT OF HUMAN GROWTH HORMONE IN MAN

1958 • 81 citations

The 20,000-dalton structural variant of human growth hormone: Lack of some early insulin-like effects

1979 • 79 citations

GROWTH-HORMONE RELEASE BY GLUCAGON

1969 • 78 citations

Growth hormone: deletions in the protein and introns in the gene

1980 • 78 citations

Growth Hormone and Lipolysis: A Reevaluation^*

1983 • 78 citations

Growth hormone secretion in response to arginine infusion in normal and diabetic subjects: relationship to blood glucose levels.

1968 • 78 citations

Exogenous growth hormone inhibits growth hormone-releasing factor-induced growth hormone secretion in normal men.

1986 • 77 citations

Is Extrapancreatic Tumor Hypoglycemia Associated with Elevated Levels of Insulin-Like Growth Factor II?*

1982 • 77 citations

SERUM-GROWTH HORMONE AND GLUCOSE INTOLERANCE IN RENAL FAILURE

1968 • 77 citations

Studies on the Bioassayable Growth Hormone-Like Activity of Plasma

1978 • 76 citations

The Location of the Chemoreceptor Controlling Growth Hormone Secretion during Hypoglycemia in Primates

1972 • 76 citations

Monoclonal Antibodies to the Rabbit Liver Growth Hormone Receptor: Production and Characterization*

1984 • 75 citations

Growth Hormone Stimulates Islet B-Cell Replication in Neonatal Rat Pancreatic Monolayer Cultures

1983 • 70 citations

THE EFFECTS OF GROWTH HORMONE ON CARBOHYDRATE AND LIPID METABOLISM IN THE DOG^*

1968 • 70 citations

Anabolic effects of human growth hormone and high caloric feedings following thermal injury

1975 • 69 citations

Separation of the Effects of Growth Hormone on Muscle Amino Acid Transport and Protein Synthesis

1964 • 69 citations

SOME EFFECTS OF PURIFIED PITUITARY GROWTH HORMONE ON CARBOHYDRATE METABOLISM IN THE RAT¹

1950 • 68 citations

Somatomedin Activity and Diabetic Control in Children with Insulin-Dependent Diabetes

1979 • 68 citations

Suppression of the Growth Hormone (GH) Response to Clonidine and GH-Releasing Hormone by Exogenous GH*

1986 • 68 citations

The Regulation of Plasma Ketone Body Concentration by Counter-regulatory Hormones in Man: II. Effects of Growth Hormone in Diabetic Man

1978 • 66 citations

Pituitary Growth Hormone Essential for Regulation of Serum Cholesterol

1970 • 66 citations

Comparison of Somatomedin Activity in Perfusates of Normal and Hypophysectomized Rat Livers With and Without Added Growth Hormone

1976 • 65 citations

Pituitary Response to Growth Hormone–releasing Factor in Diabetes: Failure of Glucose-mediated Suppression

1984 • 65 citations

EFFECT OF A SMALL DECREASE IN BLOOD-GLUCOSE ON PLASMA-GROWTH-HORMONE AND URINARY EXCRETION OF CATECHOLAMINES IN MAN

1966 • 64 citations

Impaired Somatomedin Generation Test in Children with Insulin-dependent Diabetes Mellitus

1985 • 64 citations

A Growth Hormone Binding Protein in Normal Human Serum

1964 • 64 citations

Influence of Physiologic Fluctuations in Plasma Growth Hormone on Glucose Tolerance

1969 • 63 citations

Metabolic effects of acute and prolonged growth hormone excess in normal and insulin-deficient man

1981 • 63 citations

Serum glucose, insulin, and growth hormone in chronic hepatic cirrhosis.

1969 • 61 citations

Effect of subacute administration of human growth hormone on various serum lipid and hormone levels of hypercholesterolemic and normocholesterolemic subjects

1974 • 61 citations

Diurnal Growth Hormone and Glucose Abnormalities in Unstable Diabetics: Studies of Ambulatory-Fed Subjects during Continuous Blood Glucose Analysis

1972 • 60 citations

Inhibition of Endogenous Growth Hormone Secretion by Exogenous Growth Hormone Infusion in the Rhesus Monkey¹

1970 • 59 citations

The pathogenesis of diabetic angiopathy and growth hormone.

1971 • 58 citations

Human growth hormone as a regulator of blood glucose concentration and as a diabetogenic substance

1968 • 58 citations

Regulation of Growth Hormone Release: Evidence against Negative Feedback in Rat Pituitary Cells*

1981 • 58 citations

Structure, Expression, and Evolution of Growth Hormone Genes

1982 • 57 citations

ABNORMAL GROWTH HORMONE RESPONSE TO INGESTION OF GLUCOSE IN JUVENILE DIABETICS

1969 • 56 citations

Effect of Nicotinic Acid Administration on Plasma Growth Hormone Concentrations.

1967 • 56 citations

Recent advances in the biochemistry and physiology of the insulin-like growth factor/somatomedin family

1983 • 56 citations

EFFECT OF HUMAN GROWTH HORMONE IN HYPOPHYSECTOMISED DIABETIC SUBJECTS

1958 • 55 citations

Sulfation factor regulation of skeletal growth

1971 • 55 citations

Biosynthetic 20-kilodalton methionyl-human growth hormone has diabetogenic and insulin-like activities.

1985 • 55 citations

Acute Metabolic Responses to Myocardial Infarction

1969 • 53 citations

Human Growth Hormone Release in Sleep: Nonsuppression by Acute Hyperglycemia¹

1971 • 53 citations

Serum cholesterol and triglycerides in children with growth hormone deficiency

1979 • 53 citations

STUDIES IN THE PHYSIOLOGICAL PROPERTIES OF THE GROWTH-PROMOTING EXTRACTS OF THE ANTERIOR HYPOPHYSIS*

1930 • 49 citations

"Growth" and the Diabetogenic Action of Anterior Pituitary Preparations

1941 • 49 citations

Biological Activity of Bacterial Derived Human Growth Hormone in Adipose Tissue of Hypophysectomized Rats*

1984 • 49 citations

The purification and partial characterization of an insulin-like protein from human serum.

1975 • 49 citations

Absent Sleep Peak of Growth Hormone Release in Blind Subjects: Correlation with Sleep EEG Stages

1971 • 48 citations

THE EFFECT OF PLASMA GLUCOSE ON THE GROWTH HORMONE RESPONSE TO HUMAN PANCREATIC GROWTH HORMONE RELEASING FACTOR IN NORMAL SUBJECTS

1984 • 48 citations

Direct Stimulation by Growth Hormone of Glucagon and Insulin Release from Isolated Rat Pancreas

1976 • 48 citations

Growth hormone's role in diabetic microangiopathy.

1976 • 47 citations

Physiological and Clinical Studies of GRF and GH

1986 • 47 citations

Effect of growth hormone on acute glucagon and insulin release.

1979 • 47 citations

ORAL GLUCOSE INHIBITS GROWTH HORMONE SECRETION INDUCED BY HUMAN PANCREATIC GROWTH HORMONE RELEASING FACTOR 1–44 IN NORMAL MAN

1984 • 47 citations

High 24-hour Level of Serum Growth Hormone in Juvenile Diabetics

1969 • 46 citations

Abnormalities of growth hormone regulation in acute intermittent porphyria

1967 • 46 citations

Effects of Insulin and Growth Hormone on the Flux Kates of Plasma Glucose and Plasma Free Fatty Acids in Man

1970 • 46 citations

The Relation Between the Growth and Diabetogenic Effects of the So-Called Growth Hormone of the Anterior Pituitary

1964 • 45 citations

Studies on “Big” Growth Hormone from Human Plasma and Pituitary

1974 • 44 citations

Influence of Growth Hormone on Insulin Secretion: Studies of Growth-Hormone Deficient Subjects

1967 • 44 citations

Characterization of Growth Hormone of Different Molecular Weights in Rat, Dog and Human Pituitaries

1972 • 44 citations

Structures of the somatotropin receptor and prolactin receptor on rat hepatocytes characterized by affinity labelling

1984 • 44 citations

Effects of Growth Hormone on Protein and Carbohydrate Metabolism

1957 • 43 citations

Affinity purification and structural characterization of a specific binding protein for human growth hormone in human serum

1986 • 42 citations

Studies on the Mechanism of the Antilipolytic Effects of Growth Hormone¹²

1976 • 42 citations

Daily production and metabolic clearance of growth hormone in juvenile diabetes mellitus

1973 • 41 citations

Early and Late Effects of Growth Hormone on the Metabolism of Glucose in Adipose Tissue

1965 • 40 citations

STIMULATION BY FOOD OF PERIPHERAL PLASMA IMMUNOREACTIVE GROWTH HORMONE RELEASING FACTOR

1985 • 39 citations

Effects of insulin-like growth factors on chick embryo hepatocytes

1985 • 39 citations

The Antilipolytic, Insulin-Like Effect of Growth Hormone Is Caused by a Net Decrease of Hormone-Sensitive Lipase Phosphorylation*

1984 • 39 citations

Effect of Lipid and Ketone Infusions on Insulin-Induced Growth Hormone Elevations in Rhesus Monkeys

1969 • 39 citations

Kinetics of the Somatomedin C/Insulin-Like Growth Factor I: Response to Exogenous Growth Hormone (GH) in GH-Deficient Children *

1982 • 38 citations

Hyperglycemic Activity of the 20,000-Dalton Variant of Human Growth Hormone

1981 • 38 citations

Profiles of metabolic control in diabetic children — Frequency of asymptomatic nocturnal hypoglycemia

1981 • 38 citations

Properties of Human Growth Hormone Polypeptides: Purified from Pituitary Extracts and Synthesized in Monkey Kidney Cells and Bacteria

1982 • 38 citations

Hypoglycemic Threshold for Human Growth Hormone Release

1970 • 37 citations

Effects of Human Somatomedin Preparations on Membrane Transport and Protein Synthesis in the Isolated Rat Diaphragm

1974 • 37 citations

Current concepts of somatomedin and other biologically related growth factors

1976 • 37 citations

THE PITUITARY GLAND AND CARBOHYDRATE METABOLISM

1940 • 36 citations

SEVERE RETINOPATHY AND MILD CARBOHYDRATE INTOLERANCE: POSSIBLE ROLE OF INSULIN DEFICIENCY AND ELEVATED CIRCULATING GROWTH HORMONE

1985 • 36 citations

IMPORTANCE OF PITUITARY HORMONES IN ÆTIOLOGY OF DIABETIC KETOACIDOSIS

1978 • 36 citations

Familial combined hyperlipoproteinemia. Evidence for a role of growth hormone deficiency in effecting its manifestation.

1980 • 36 citations

Hourly Variations in Plasma Concentrations of Growth Hormone and Insulin and in Amino Acid Uptake and Incorporation into Protein in Diaphragm Muscle of the Rat*

1978 • 36 citations

Somatomedin activity and diabetic control in children with insulin-dependent diabetes

1979 • 35 citations

Relationship of protein synthesis and cyclic AMP to lipolytic action of growth hormone and glucocorticoids

1971 • 35 citations

Hormonal genesis of glucose intolerance following hypoglycemia

1968 • 35 citations

Antilipolytic effects of growth hormone

1970 • 34 citations

Insulin and Protein Synthesis

1970 • 34 citations

Insulin-like growth factors in patients with nonislet cell tumors and hypoglycemia

1986 • 34 citations

Differentiation of Growth Hormone from the Pituitary Factor Which Produces Diabetes

1952 • 34 citations

Growth hormone stimulates islet B-cell replication in neonatal rat pancreatic monolayer cultures

1983 • 33 citations

Recombinant Deoxyribonucleic Acid-Derived 22K- and 20K-Human Growth Hormone Generate Equivalent Diabetogenic Effects during Chronic Infusion in Dogs*

1987 • 33 citations

INFLUENCE OF GROWTH HORMONE ON SPLANCHNIC GLUCOSE PRODUCTION IN MAN

1977 • 33 citations

Insulin-Like and Diabetogenic Effects of Growth Hormone in Healthy Subjects, Diabetics, and Low Insulin Responders*

1979 • 32 citations

The diabetogenic action of human growth hormone: Glucose - fatty acid interrelationships

1968 • 31 citations

Impaired somatomedin generation test in children with insulin-dependent diabetes mellitus

1985 • 31 citations

Effects of Growth Hormone on Glucose Utilization in Diaphragm Muscle in the Absence of Increased Lipolysis

1967 • 31 citations

Comparison of Several Insulin-Like Effects of Growth Hormone

1979 • 30 citations

THE LIVER AS A SOURCE OF SOMATOMEDIN

1976 • 30 citations

Impaired growth hormone response to human pancreatic growth hormone releasing factor [GRF (1?44)] in type 2 (non-insulin-dependent) diabetes

1984 • 30 citations

Growth and Experimental Insulin-insensitive Diabetes

1944 • 29 citations

Diabetogenic polypeptide from human pituitaries similar to that excreted by proteinuric diabetic patients

1972 • 28 citations

Characteristics of Growth Hormone Secretion in Clinically Stable Diabetes

1979 • 28 citations

Hepatic Clearance of Human Growth Hormone1

1972 • 27 citations

Rapid Modulation of Protein Synthesis in Normal Rats by Specific Neutralization and Replacement of Growth Hormone*

1982 • 26 citations

In VitroEffects of Growth Hormone on the Number and Activity of Ribosomes Engaged in Protein Synthesis in the Isolated Rat Diaphragm1

1971 • 26 citations

THE EFFECT OF HUMAN GROWTH HORMONE IN HYPOPHYSECTOMIZED HUMAN DIABETIC SUBJECTS

1959 • 26 citations

Acute Reduction of Plasma Nonesterified Fatty Acid by Growth Hormone in Hypophysectomized and Houssay Rats1

1965 • 25 citations

Role of Lipolytic and Glucocorticoid Hormones in the Development of Diabetic Ketosis

1972 • 25 citations

Analysis of Refractoriness to the Effects of Growth Hormone on Amino Acid Transport and Protein Synthesis in Diaphragms of Young Normal Rats*

1980 • 25 citations

ACUTE EFFECTS OF EXOGENOUS GROWTH HORMONE IN MAN: TIME- AND DOSE-BOUND MODIFICATION OF GLUCOSE TOLERANCE AND GLUCOSE-INDUCED INSULIN RELEASE

1975 • 24 citations

Studies of the Composition and Radioreceptor Activity of “Big” and “Little” Human Growth Hormone

1977 • 24 citations

The biology of growth hormone

1976 • 24 citations

Changes in plasma growth hormone in diabetic and nondiabetic subjects during the glucose clamp

1987 • 24 citations

No Evidence For Increased Growth Hormone Responses to Growth Hormone-Releasing Hormone in Patients With Diabetic Retinopathy

1987 • 22 citations

Human Pituitary Tissue Secretes a Potent Growth Factor for Chondrocyte Proliferation*

1986 • 21 citations

Effect of thyroxine and growth hormone on the hypercholesterolemia of growth hormone deficiency

1984 • 21 citations

Serum glucose, insulin, and growth hormone in chronic hepatic cirrhosis

1969 • 21 citations

The distribution of radioactivity in the tissues of the rat after the administration of radioactive growth hormone preparations.

1954 • 20 citations

Inhibition of Sleep-Related Growth Hormone Release by Elevated Free Fatty Acids

1972 • 20 citations

On the diabetogenic effect of growth hormone in man: effects of growth hormone on glucagon and insulin secretion

1981 • 20 citations

Effect of Medroxyprogesterone Acetate on the Sleep Induced Peak of Growth Hormone Secretion

1971 • 20 citations

Effects of Human Growth Hormone in Elderly Males

1969 • 20 citations

Effect of growth hormone replacement on development of hypothyroidism and hyperlipidemia

1985 • 20 citations

Effect of insulin on growth hormone-induced metabolic derangements in diabetes

1986 • 19 citations

Effect of hypophysectomy on liver enzymes involved in glycogenolysis and in glucogenesis

1959 • 18 citations

Absence of an effect of chronic administration of growth hormone on serum lipids

1975 • 18 citations

The effect of growth hormone on the metabolism of lipids and on urea formation by the perfused rat liver

1966 • 16 citations

RISK OF HYPOGLYCAEMIA WITH ALTERNATE-DAY GROWTH HORMONE INJECTIONS

1987 • 16 citations

Deranged α-Adrenergic Regulation of Growth Hormone Secretion in Poorly Controlled Diabetes: Reversal of the Exaggerated Response to Clonidine after Continuous Subcutaneous Insulin Infusion

1985 • 15 citations

Metabolic Clearance Rate of Growth Hormone in Juvenile Diabetes Mellitus

1972 • 15 citations

The effect of synthetic fragment 31–44 of human growth hormone on glucose uptake by isolated adipose tissue

1983 • 15 citations

Early Insulin Synergistic Activity of Growth Hormone

1969 • 15 citations

ACUTE SUPPRESSIVE EFFECT OF HUMAN GROWTH HORMONE ON BASAL INSULIN SECRETION IN MAN

1975 • 15 citations

Evidence for a Central Abnormality in the Regulation of Growth Hormone Secretion in Insulin‐dependent Diabetes

1984 • 15 citations

Effects of nutritional status and the pituitary on the acute plasma free fatty acid and glucose responses of rats to growth hormone administration

1968 • 14 citations

The Effect of Hypoglycaemia on Oral Glucose Tolerance in Normal Subjects and Patients with Pituitary and Adrenal Disorders

1970 • 14 citations

Somatomedin Generation by Perfused Livers

1975 • 13 citations

Absence of Hyperlipidemia in Acromegaly

1972 • 13 citations

Growth Hormone and Diabetes

1966 • 12 citations

Studies on the Heterogeneity and Serum Binding of Human Growth Hormone

1967 • 12 citations

LACK OF RELATION BETWEEN PLASMA-GROWTH-HORMONE LEVELS AND SMALL DECREMENTS IN BLOOD-SUGAR

1968 • 11 citations

Growth Hormone Response to Hyperinsulinaemia in Insulin‐dependent Diabetics Comparison of Patients With and Without Retinopathy

1984 • 10 citations

No evidence for increased growth hormone responses to growth hormone-releasing hormone in patients with diabetic retinopathy

1987 • 9 citations

Evidence for a biologically active, carrier-bound form of non-suppressible insulin-like activity (nsila) in human serum

1983 • 9 citations

THE INFLUENCE OF HYPOPHYSECTOMY AND OF GROWTH HORMONE ADMINISTRATION ON THE OXIDATION OF PALMITATE-1-C¹⁴BY THE UNANESTHETIZED RAT¹

1961 • 9 citations

The Somatomedins

1981 • 8 citations

Influence of Fasting on Changes in Glucose Metabolism Induced by Growth Hormone Injection in the Normal Dog

1970 • 8 citations

XANTHOMA ACCOMPANIED BY HYPERCHOLESTEROLEMIA, OCCURRING IN AN OTHERWISE NORMAL INDIVIDUAL, AND IN AN INDIVIDUAL WITH ACROMEGALY AND DIABETES

1933 • 7 citations

Acute suppressive effect of human growth hormone on insulin release induced by glucagon and tolbutamide in man.

1975 • 6 citations

A Hybrid Noncovalent Complex of Fragments of Porcine and Human Growth Hormones with Diabetogenic Activity*

1983 • 5 citations

A Study in the Pathogenesis of Hyperlipemia in a Patient with Acromegaly and Diabetes Mellitus

1969 • 5 citations

Multiple Forms of Human Growth Hormone

1986 • 3 citations

Structural Studies of the Growth Hormone Receptor by Affinity Labeling

1986 • 1 citations

Deleted Work

1955 • 0 citations