The structure of a myelin basic protein-associated idiotope

Sequences of proteins of immunological interest

1984 • 3,427 citations

Canonical structures for the hypervariable regions of immunoglobulins

1987 • 1,357 citations

Conformations of immunoglobulin hypervariable regions

1989 • 1,165 citations

The T Lymphocyte in Experimental Allergic Encephalomyelitis

1990 • 1,005 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

Continuous and discontinuous protein antigenic determinants

1986 • 582 citations

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy

1988 • 555 citations

T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis

1986 • 471 citations

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex.

1989 • 456 citations

Anti-Idiotypic Network Induced by T Cell Vaccination Against Experimental Autoimmune Encephalomyelitis

1988 • 409 citations

Developmentally Controlled Expression of Immunoglobulin V _H Genes

1985 • 349 citations

Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar V alpha and V beta chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different.

1989 • 321 citations

mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification

1983 • 301 citations

Antigenic Specificities Related to the Cold Agglutinin Activity of Gamma M Globulins

1968 • 243 citations

Serine esterase in cytolytic T lymphocytes

1986 • 240 citations

A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen

1989 • 213 citations

Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype.

1991 • 204 citations

Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis.

1988 • 179 citations

Nucleic acid sequence of an internal image-bearing monoclonal anti-idiotype and its comparison to the sequence of the external antigen.

1986 • 161 citations

Influence of protein flexibility and peptide conformation on reactivity of monoclonal anti-peptide antibodies with a protein alpha-helix.

1987 • 160 citations

Anti-oxazolone hybridomas and the structure of the oxazolone idiotype.

1983 • 114 citations

Protection from experimental allergic encephalomyelitis conferred by a monoclonal antibody directed against a shared idiotype on rat T cell receptors specific for myelin basic protein.

1988 • 104 citations

Immunoglobulin-deficient rats fail to develop experimental allergic encephalomyelitis

1983 • 99 citations

Inhibition of Self-Binding Antibodies (Autobodies) by a V_H-Derived Peptide

1988 • 95 citations

Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis

1992 • 86 citations

Sequences of the cell-attachment sites of reovirus type 3 and its anti-idiotypic/antireceptor antibody: modeling of their three-dimensional structures.

1988 • 86 citations

Delineation of a cross-reactive idiotype on human autoantibodies with antibody against a synthetic peptide.

1984 • 72 citations

T cell receptor sequences from encephalitogenic T cells in adult Lewis rats suggest an early ontogenic origin.

1992 • 70 citations

The idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.

1985 • 63 citations

Location of antigenic epitopes on antibody molecules

1986 • 58 citations

Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypes.

1984 • 57 citations

Specific modulation of T cells and murine experimental allergic encephalomyelitis by monoclonal anti-idiotypic antibodies.

1993 • 57 citations

A three-dimensional model of an anti-lysozyme antibody

1987 • 55 citations

Synthetic idiotypes: The third hypervariable region of murine anti-dextran antibodies

1983 • 51 citations

Cloning and sequencing of imniunoglobulin variable-region genes using degenerate oligodeoxy-ribonucleotides and polymerase chain reaction

1989 • 50 citations

The presence of immunoreactive myelin basic protein peptide in urine of persons with multiple sclerosis

1987 • 44 citations

VH and VL gene usage by murine IgG antibodies that bind autologous insulin.

1990 • 42 citations

Epitopes of immunoreactive myelin basic protein in human cerebrospinal fluid

1986 • 40 citations

Identification of human anti-DNA, anti-RNP, anti-SM, and anti-SS-A serum antibodies bearing the cross-reactive 16/6 idiotype.

1987 • 40 citations

Experimental allergic encephalomyelitis in the Lewis rat: farther delineation of active sites in guinea pig and bovine myelin basic proteins.

1977 • 37 citations

Monoclonal idiotypic and anti-idiotypic antibodies produced by immunization with peptides specified by a region of human myelin basic protein mRNA and its complement

1989 • 33 citations

Experimental Allergic Encephalomyelitis in the Lewis Rat: Further Delineation of Active Sites in Guinea Pig and Bovine Myelin Basic Proteins

1977 • 32 citations

Oligoclonal Banding in MS^a

1984 • 31 citations

Do antibodies recognize amino acid side chains of protein antigens independently of the carbon backbone?

1988 • 29 citations

The autoreactive T cell population in experimental allergic encephalomyelitis: T cell receptor β-chain rearrangements

1988 • 25 citations

Rabbit anti-human CSF IgG. I. Characterization of anti-idiotype antibodies produced against MS CSF and detection of cross-reactive idiotypes in several MS CSF.

1982 • 22 citations

Anti-peptide antibodies detect a lupus-related interspecies idiotype that maps to H chain CDR2.

1990 • 22 citations

Molecular structure of a cross-reactive idiotype on autoantibodies recognizing parenchymal self.

1993 • 20 citations

Identification of a common idiotype on myelin oligodendrocyte glycoprotein-specific autoantibodies in chronic relapsing experimental allergic encephalomyelitis

1989 • 19 citations

High frequency expression of S107 VH genes by peritoneal B cells of B10.H-2aH-4bP/WTS mice.

1990 • 19 citations

An idiotype shared by monoclonal antibodies to different peptides of human myelin basic protein.

1990 • 18 citations

Interstrain cross-reactive idiotypes on monoclonal antibodies to an encephalitogenic myelin basic protein peptide

1992 • 16 citations

Anti-idiotypic antibodies of a predefined specificity generated against cdrsvn synthetic peptides define a private anti-CD4 idiotype

1990 • 16 citations

The analysis of internal image-bearing anti-idiotypic monoclonal antibody in relation to carcinoembryonic antigen.

1993 • 16 citations

A structural basis for the internal image in the idiotypic network: Antibodies against synthetic Ab2-D regions cross-react with the original antigen

1985 • 16 citations

Probing the idiotype/anti-idiotype antibody interaction with a set of synthetic peptide homologues

1991 • 5 citations