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A current genotoxicity database for heterocyclic thermic food mutagens. I. Genetically relevant endpoints.

Data up to Jan 2025

Published1986
Citations15
References56

Total Citations Per Year

Abstract

References (56)

Revised methods for the Salmonella mutagenicity test

1983 • 7,295 citations

THE CHEMISTRY AND BIOLOGY OF LEFT-HANDED Z-DNA

1984 • 1,149 citations

REVISED METHODS FOR THE SALMONELLA MUTAGENICITY TEST

1984 • 428 citations

Isolation and characterization of new mutagens from fried ground beef

1984 • 180 citations

Mutagens from the cooking of food

1981 • 130 citations

Formation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in a model system by heating creatinine, glycine and glucose

1984 • 116 citations

Mutagenic activity of amino acid pyrolyzates in Salmonella typhimurium TA 98

1977 • 107 citations

Carcinogenicity in mice and rats of heterocyclic amines in cooked foods.

1986 • 102 citations

Comparative genotoxic effects of the cooked-food-related mutagens Trp-P-2 and IQ in bacteria and cultured mammalian cells

1983 • 94 citations

Formation of 2-amino-3,7,8-trimethylimidazo[4,5-ƒ]quinoxaline, a new mutagen, by heating a mixture of creatinine, glucose and glycine

1984 • 67 citations

Induction of sister-chromatid exchanges by mutagens from amino acid and protein pyrolysates

1980 • 62 citations

Mutagenicities of the pyrolyzates of peptides and proteins

1978 • 59 citations

Mutagenic activity of heterocyclic amines in Chinese hamster lung cells with diphtheria toxin resistance as a marker

1983 • 52 citations

In vitro transformation of hamster embryo cells with tryptophan pyrolysis products.

1977 • 44 citations

There is a correlation between the DNA affinity and mutagenicity of several 3-amino-1-methyl-5H-pyrido[4,3-b]indoles.

1980 • 31 citations

In vivo cytogenetic effects of the cooked-food-related mutagens Trp-P-2 and IQ in mouse bone marrow

1984 • 31 citations

The Chemistry and Biology of Left-Handed Z-DNA

1984 • 31 citations

Identification of Mutagens from the Cooking of Food

1984 • 31 citations

Structural identification of a modified base in DNA covalently bound with mutagenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole.

1979 • 28 citations

Malignant transformation in vitro by tryptophan pyrolysis products.

1978 • 27 citations

Actions of amino-β-carbolines on induction of sister-chromatid exchanges

1983 • 27 citations

In vitro transformation of hamster embryo cells with a glutamic acid pyrolysis product

1979 • 25 citations

Structure of a base in DNA modified by Glu-P-1.

1979 • 24 citations

Deoxyribonucleic acid modification by mutagenic 3-amino-1-methyl-5H-pyrido(4,3-b)indole: The chemical events.

1984 • 22 citations

Mutagens in cooked foods

1984 • 22 citations

Bacterial mutagenicity of natural materials, pyrolysis products and additives in foodstuffs and their association with genotoxic effects in mammals

1983 • 22 citations

Rat liver microsome-mediated binding to DNA of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a potent mutagen isolated from tryptophan pyrolysate.

1978 • 21 citations

Aroclor 1254 pretreatment enhances the DNA repair response to amino acid pyrolysate mutagens in primary cultures of rat hepatocytes

1983 • 21 citations

Modification of nucleic acids with muta-carcinogenic heteroaromatic amines in vivo

1982 • 21 citations

Comparative mutagenic efficiencies of the DNA adducts from the cooked-food-related mutagens Trp-P-2 and IQ in CHO cells

1985 • 21 citations

Sequence selective modification of DNA with muta-carcinogenic 2-amino-6-methyldipyrido[1,2-a:3′,2′-d]imidazole

1983 • 21 citations

Neoplastic transformation of balb 3T3 mouse embryo fibroblasts by the beef extract mutagen 2-amino-3-methylimidazo [4,5-d] quinoline

1983 • 19 citations

Non-covalent interaction with DNA of the mutagens 2-amino-dipyrido[1,2-a:3′,2′-d]imidazole and methyl-substituted isomers

1980 • 19 citations

DNA‐biding of IQ, Me‐IQ and Me‐IQx, strong mutagens found in broiled foods

1982 • 17 citations

Possible genotoxic carcinogens in foods in relation to cancer causation.

1983 • 17 citations

Chromosome Aberrations and Sister Chromatid Exchanges Induced by Tryptophan Pyrolysates, Trp-P-1 and Trp-P-2, in Cultured Human and Chinese Hamster Cells

1980 • 16 citations

mutagenesis of amino acid pyrolysis products in chinese hamster V79 cells

1983 • 14 citations

Carcinogenicity in Mice and Rats of Heterocyclic Amines in Cooked Foods

1986 • 14 citations

Interaction of mutagens isolated from L-glutamic acid pyrolysate with DNA

1980 • 13 citations

The interaction of ionizing radiation and food pyrolysis products in producing oncogenic transformation in vitro☆

1981 • 13 citations

Comparative induction of somatic eye-color mutations and sex-linked recessive lethals in Drosophila melanogaster by tryptophan pyrolysates

1983 • 13 citations

DNA damage of mammalian cells by the beef extract mutagen 2-amino-3-methylimidazo[4,5-ƒ]quinoline

1983 • 10 citations

Mutagens in Cooked Foods-Metabolism and Genetic Toxicity

1984 • 10 citations

Identification of Mutagens from the Cooking of Food

1984 • 9 citations

Antagonizing effect of 3-aminoharman on induction of sister-chromatid exchanges by mutagens

1984 • 9 citations

Chromosomal aberrations and morphological transformation of hamster embryonic cells induced by L-tryptophan pyrolyzate in vitro

1978 • 8 citations

Enzymatic studies on binding of mutagenic principles in tryptophan pyrolysate to DNA.

1980 • 7 citations

Induction of 8-azaguanine or ouabain resistant somatic mutation of Chinese hamster lung cells by treatment with tryptophan pyrolysis products

1980 • 7 citations

Comparative mutagenesis by aminofluorene derivatives A possible effect of DNA configuration

1984 • 7 citations

Pyrolytic products from tryptophan and glutamic acid are positive in the mammalian spot test

1983 • 7 citations

Induction of Diphtheria Toxin-resistant Cells by Mutagen-carcinogens

2020 • 6 citations

Application of HPLC to the isolation of molecular targets in dosimetry studies.

1985 • 4 citations

Enzymatic Studies on Binding of Mutagenic Principles in Tryptophan Pyrolysate to DNA

1980 • 3 citations

Defective repair of tryptophan pyrolysate (Trp P-1 and Trp P-2) and aflatoxin B1 damage in xeroderma pigmentosum cells.

1983 • 2 citations

Application of HPLC to the Isolation of Molecular Targets in Dosimetry Studies

1985 • 2 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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A current genotoxicity database for heterocyclic thermic food mutagens. I. Genetically… (1986) – Environmental Health Perspectives | Metascience Observatory Explorer