There is a correlation between the DNA affinity and mutagenicity of several 3-amino-1-methyl-5H-pyrido[4,3-b]indoles.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

1970 • 1,464 citations

METHODS IN CANCER RESEARCH

1969 • 1,197 citations

Chemical Carcinogenesis

1975 • 741 citations

Epoxides in Polycyclic Aromatic Hydrocarbon Metabolism and Carcinogenesis

1974 • 739 citations

Evidence for the Binding of Polynuclear Aromatic Hydrocarbons to the Nucleic Acids of Mouse Skin : Relation between Carcinogenic Power of Hydrocarbons and their Binding to Deoxyribonucleic Acid

1964 • 687 citations

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.

1977 • 507 citations

Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens

1972 • 361 citations

The Molecular Biology of Cancer

1974 • 298 citations

Zur Frage der Entstehung maligner Tumoren

1914 • 294 citations

Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens

1972 • 225 citations

The resolution and reconstitution of the liver microsomal hydroxylation system

1974 • 223 citations

CHEMICAL MUTAGENS: PRINCIPLES AND METHODS FOR THEIR DETECTION

1972 • 186 citations

Quantitative forward mutation assay in Salmonella typhimurium using 8-azaguanine resistance as a genetic marker.

1978 • 160 citations

Interactions of norharman and harman with DNA

1977 • 144 citations

Relative sensitivities of forward and reverse mutation assays in Salmonella typhimurium.

1978 • 129 citations

Binding of tritium-labeled polycyclic hydrocarbons to DNA of mouse skin.

1967 • 118 citations

Topography of nucleic acid helixes in solution. XXIX. Steric effects on the intercalation of aromatic cations to deoxyribonucleic acid

1973 • 109 citations

Nuclear aryl hydrocarbon hydroxylase and interaction of polycyclic hydrocarbons with nuclear components

1977 • 106 citations

Sequential morphologic changes in aflatoxin B carcinogenesis in the rat.

1968 • 101 citations

Binding of metabolically activated benzo(a)pyrene to nuclear macromolecules.

1976 • 77 citations

Effects of harman and norharman on the mutagenicity and binding to DNA of benzo[a]pyrene metabolites in vitro and on aryl hydrocarbon hydroxylase induction in cell culture

1977 • 68 citations

Multiple regions of metabolic activation of carcinogenic hydrocarbons

1978 • 62 citations

Comparative studies on the 7-iodo and 7-fluoro derivatives of N-acetoxy-N-2-acetylaminofluorene: binding sites on DNA and conformational change of modified deoxytrinucleotides

1978 • 56 citations

The effect of norharman on the metabolism of benzo[a]pyrene by rat-liver microsomes in vitro in relation to its enhancement of the mutagenicity of benzo[a]pyrene

1978 • 46 citations

Studies of the interaction of the fluorophores harmine and harmaline with calf thymus DNA

1975 • 44 citations

The binding of beta-propiolactone and some related alkylating agents to DNA, RNA, and protein of mouse skin; relation between tumor-initiating power of alkylating agents and their binding to DNA.

1968 • 32 citations

Synthesis of a mutagenic principle isolated from tryptophan pyrolysate.

1977 • 31 citations

Structure-activity relationships in DNA binding and nuclear effects of aflatoxin and anlogs.

1971 • 22 citations

Rat liver microsome-mediated binding to DNA of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a potent mutagen isolated from tryptophan pyrolysate.

1978 • 21 citations

Relations Between Molecular Structure and Biological Activity: Stages in the Evolution of Current Concepts

1971 • 18 citations