Identification of Mutagens from the Cooking of Food

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

1975 • 7,413 citations

The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today

1981 • 3,794 citations

Contribution of the Environment to Cancer Incidence: An Epidemiologic Exercise

1977 • 487 citations

Mutagenicities of smoke condensates and the charred surface of fish and meat

1977 • 354 citations

Nitropyrenes: Isolation, Identification, and Reduction of Mutagenic Impurities in Carbon Black and Toners

1980 • 353 citations

Colorectal Cancer: Prevention, Epidemiology, and Screening.

1981 • 290 citations

Formation of Mutagens in Beef and Beef Extract During Cooking

1978 • 264 citations

Benzo( a )pyrene and Other Polynuclear Hydrocarbons in Charcoal-Broiled Meat

1964 • 238 citations

Effects of temperature and time on mutagen formation in pan-fried hamburger

1979 • 237 citations

Mutagens, carcinogens, and tumor promoters in our daily food

1982 • 233 citations

Environmental Carcinogens selected Methods of Analysis

1982 • 198 citations

Mutagenicity of flavone derivatives.

1977 • 193 citations

Molecular Interrelations of Nutrition and Cancer

1982 • 190 citations

Isolation and characterization of new mutagens from fried ground beef

1984 • 180 citations

Carcinogenicity in Mice of Mutagenic Compounds from a Tryptophan Pyrolyzate

1981 • 178 citations

Mutagenicity of 1,2-dicarbonyl compounds: Maltol, kojic acid, diacetyl and related substances

1979 • 155 citations

Potent novel mutagens produced by broiling fish under normal conditions.

1980 • 154 citations

Mutagenicity of amino-α-carbolines in pyrolysis products of soybean globulin

1978 • 154 citations

STRUCTURE OF A POTENT MUTAGEN ISOLATED FROM FRIED BEEF

1981 • 146 citations

Determination of mutagens, amino-α-carbolines in grilled foods and cigarette smoke condensate

1981 • 145 citations

Demonstration of mutagenicity of aniline and o-toluidine by norharman.

1977 • 144 citations

Mutagenicities of protein pyrolysates

1977 • 142 citations

Isolation and structure determination of mutagenic substances in L-glutamic acid pyrolysate.

1978 • 139 citations

Mutagens from the cooking of food

1981 • 130 citations

Isolation and structure studies of mutagenic principles in amino acid pyrolysates.

1978 • 119 citations

Mutagenic Factors in Cooked Foods

1979 • 112 citations

Detection of potent mutagens, Trp-P-1 and Trp-P-2, in broiled fish

1980 • 109 citations

Mutagenic activity of amino acid pyrolyzates in Salmonella typhimurium TA 98

1977 • 107 citations

Differences in effects of norharman with various classes of chemical mutagens and amounts of S-9

1978 • 106 citations

Amino-α-carbolines as mutagenic agents in cigarette smoke condensate

1980 • 96 citations

Comparative genotoxic effects of the cooked-food-related mutagens Trp-P-2 and IQ in bacteria and cultured mammalian cells

1983 • 94 citations

Heterocyclic compounds found in cooked meats

1980 • 91 citations

Nitrates and Nitrites: Ingestion, Pharmacodynamics, and Toxicology

1982 • 87 citations

Relation between chemical constituents of tobacco and mutagenic activity of cigarette smoke condensate

1977 • 86 citations

STRUCTURE AND CHEMICAL SYNTHESIS OF ME-IQ, A POTENT MUTAGEN ISOLATED FROM BROILED FISH

1980 • 86 citations

The effect of temperature on the formation of mutagens in heated beef stock and cooked ground beef

1979 • 85 citations

Effects of meat composition and cooking conditions on mutagen formation in fried ground beef

1983 • 82 citations

Mutagens from the cooking of food. II. Survey by Ames/Salmonella test of mutagen formation in the major protein-rich foods of the American diet

1982 • 81 citations

Formation of mutagens in cooked foods. I. Beef

1979 • 80 citations

Formation of mutagens in cooked foods. III. Isolation of a potent mutagen from beef

1980 • 76 citations

Review of polycyclic aromatic hydrocarbons in foods

1969 • 71 citations

A microcomputer program for analyzing Ames test data

1983 • 71 citations

Carcinogenic activity of 3-amino-1-methyl-5H-pyrido [4,3-b]indole (Trp-P-2), a pyrolysis product of tryptophan

1981 • 67 citations

Chemical synthesis of 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ), a potent mutagen isolated from broiled fish.

1980 • 66 citations

Utilization of protein resources

1981 • 63 citations

Induction of sister-chromatid exchanges by mutagens from amino acid and protein pyrolysates

1980 • 62 citations

Modification of DNA with potent mutacarcinogenic 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole isolated from a glutamic acid pyrolysate: structure of the modified nucleic acid base and initial chemical event caused by the mutagen

1982 • 61 citations

Metabolic activation of a mutagen, 2-amino-6-methyldipyrido-[1,2-a:3′,2′-d]imidazole. Identification of 2-hydroxyamino-6-methyldipyrido[1,2-a:3′,2′-d]imidazole and its reaction with DNA

1980 • 60 citations

An XAD-2 resin method for efficient extraction of mutagens from fried ground beef

1982 • 59 citations

Mutagenicities of the pyrolyzates of peptides and proteins

1978 • 59 citations

Determination and identification of polycyclic aromatic hydrocarbons in smoked and charcoal‐broiled food products by high pressure liquid chromatography and gas chromatography

1976 • 58 citations

Clastogenic and Mutagenic Activities of Maillard Reaction Model Systems

1981 • 55 citations

A potent mutagen in broiled fish. Part 1. 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline

1981 • 54 citations

Effect of methyl substitution on mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline isolated from broiled sardine

1981 • 51 citations

Formation of mutagens in cooked foods. II. Foods with high starch content

1980 • 50 citations

Mutagenic activity of pyrazine derivatives: A comparative study with Salmonella typhimurium, Saccharomyces cerevisiae and Chinese hamster ovary cells

1980 • 50 citations

Synthesis of mutagenic principles isolated from L-glutamic acid pyrolysate.

1978 • 44 citations

Clastogenic activity of caramel and caramelized sugars

1981 • 42 citations

Determination of benzo[a]pyrene in smoked, cooked and toasted food products

1979 • 42 citations

SYNTHESES OF POTENT MUTAGENS IN TRYPTOPHAN PYROLYSATES

1977 • 42 citations

Mutagens from the cooking of food. III. Survey by Ames/Salmonella test of mutagen formation in secondary sources of cooked dietary protein

1982 • 37 citations

Isolation and structure determination of a mutagenic substance in L-lysine pyrolysate.

1978 • 37 citations

Enhancing effect of harman on mutagenicity in Salmonella

1977 • 36 citations

Mutagenicities of γ-carboline derivatives related to potent mutagens found in tryptophan pyrolysates

1980 • 35 citations

Fractionation of a mutagenic principle from broiled fish by high-pressure liquid chromatography

1979 • 35 citations

Isolation of mutagens from bacterial nutrients containing beef extract

1978 • 35 citations

Chemical Mutagens. Principles and Methods for their Detection Vol. 4

1978 • 34 citations

Antimutagenic activity of browning reaction products

1982 • 31 citations

Formation of mutagens in sugar-amino acid model systems

1983 • 29 citations

Mutagenecity of the browing mixtures by amino-carbonyl reactions on Salmonella typhimurium TA 100.

1980 • 29 citations

Induction of enzyme-altered islands in rat liver by tryptophan pyrolysis products

1979 • 29 citations

Structural identification of a modified base in DNA covalently bound with mutagenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole.

1979 • 28 citations

In vitro transformation of hamster embryo cells with a glutamic acid pyrolysis product

1979 • 25 citations

Structure of a base in DNA modified by Glu-P-1.

1979 • 24 citations

SYNTHESIS OF 2-AMINO-3,8-DIMETHYLIMIDAZO[4,5-f]QUINOXALINE (Me-IQx), A POTENT MUTAGEN ISOLATED FROM FRIED BEEF

1981 • 23 citations

Isolation of 2-amino-9H-pyrido[2,3-b]indole and 2-amino-3-methyl-9H-pyrido[2,3-b]indole as mutagens from pyrolysis product of tryptophan.

1979 • 21 citations

Modification of nucleic acids with muta-carcinogenic heteroaromatic amines in vivo

1982 • 21 citations

Nitrosamine levels in human blood, urine and gastric aspirate following ingestion of foods containing potential nitrosamine precursors or preformed nitrosamines

1982 • 20 citations

Pyrolytic yields of 2-amino-9H-pyrido[2,3-b]indole and 3-amino-1-methyl-5H-pyrido[4,3-b]indole as matagens from proteins.

1979 • 20 citations

Mutagenic Analysis as a Means of Detecting Carcinogens in Foods

1978 • 19 citations

Induction of bladder cancer in mice by implanting pellets containing tryptophan pyrolysis products

1982 • 17 citations

A potent mutagen isolated from a pyrolysate of L-ornithine.

1981 • 17 citations

Syntheses of 2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline and Its Related Compounds

1982 • 17 citations

A source of error in mutagen testing of foods

1981 • 16 citations

Chromosome Aberrations and Sister Chromatid Exchanges Induced by Tryptophan Pyrolysates, Trp-P-1 and Trp-P-2, in Cultured Human and Chinese Hamster Cells

1980 • 16 citations

Effect of pH and ammonium ions on mutagenic activity in cooked beef

1981 • 16 citations

Synthesis of mutagenic heteroaromatics: 2-Aminoimidazo(4,5-f)quinolines.

1982 • 15 citations

Crystal and molecular structures of 2‐amino‐3‐methylimidazo‐[4,5‐f]‐ quinoline, a novel potent mutagen found in broiled food

1980 • 15 citations

Effect of heating methods on mutagenic activity and yield of mutagenic compounds in pyrolysis products of protein.

1980 • 13 citations

Priorities assessment for studies of mutagen production in cooked foods1

1981 • 11 citations

Synthesis, chemical characterization, and mutagenic activities of promutagens produced by pyrolysis of proteinaceous substances

1981 • 10 citations

Mutagen formation in a model beef boiling system I. Conditions with a soluble beef‐derived fraction

1984 • 9 citations

Mutagen formation in a model beef boiling system II. Effects of proteolysis and comparison of soluble fractions from several protein sources

1984 • 8 citations

Synthesis of 2-amino-9H-pyrido[2,3-b]indole isolated as a mutagenic principle from pyrolytic products of protein.

1979 • 8 citations

The Mouse Oocyte Toxicity Assay

1983 • 8 citations

Synthesis and mutagenic activity of alkyl derivatives of 2-amino-9H-pyrido(2,3-b)indole.

1981 • 8 citations

Studies on Active Principles of Tar. VIII. Production of Biological Active Substances in Pyrolyses of Amino Acids. (2). Antifungal Constituents in Pyrolysis Products of Phenylalanine

1978 • 4 citations