Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes

1980 • 1,256 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

1986 • 1,150 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes

1980 • 772 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

1984 • 564 citations

Multiple factors required for accurate initiation of transcription by purified RNA polymerase II.

1980 • 541 citations

A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene

1984 • 410 citations

Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters

1985 • 366 citations

Purification of nuclear factor I by DNA recognition site affinity chromatography.

1986 • 331 citations

Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence

1985 • 313 citations

Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences

1986 • 298 citations

Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer.

1987 • 255 citations

Molecular Cloning of the Chicken Progesterone Receptor

1986 • 243 citations

The saccharomyces and Drosophila heat shock transcription factors are identical in size and DNA binding properties

1987 • 214 citations

The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene

1981 • 195 citations

Cloning of the chicken progesterone receptor.

1986 • 177 citations

A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes

1987 • 160 citations

An immunoglobulin promoter displays cell-type specificity independently of the enhancer

1985 • 144 citations

Cell-type preference of immunoglobulin kappa and lambda gene promoters.

1985 • 118 citations

Synergism between immunoglobulin enhancers and promoters

1986 • 116 citations

The mouse immunoglobulin heavy-chain enhancer: effect on transcription in vitro and binding of proteins present in HeLa and lymphoid B cell extracts.

1986 • 114 citations

Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro.

1986 • 96 citations

Contribution of Promoter to Tissue-Specific Expression of the Mouse Immunoglobulin Kappa Gene

1985 • 76 citations