Activation of Early Gene Expression in T Lymphocytes by Oct-1 and an Inducible Protein, OAP ⁴⁰

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

The Interleukin-2 T-Cell System: A New Cell Growth Model

1984 • 935 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

New type of POU domain in germ line-specific protein Oct-4

1990 • 753 citations

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

1990 • 745 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

The Role of the T3/Antigen Receptor Complex in T-Cell Activation

1986 • 627 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

Characterization of antigen receptor response elements within the interleukin-2 enhancer.

1988 • 451 citations

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

1990 • 450 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.

1988 • 429 citations

Interleukin 2 regulates its own receptors.

1985 • 414 citations

Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

1988 • 377 citations

A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence

1988 • 360 citations

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

1990 • 353 citations

Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters.

1988 • 323 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer.

1987 • 263 citations

Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain.

1990 • 238 citations

A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain

1988 • 234 citations

Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element.

1988 • 234 citations

Interactions of the Oct-1 POU subdomains with specific DNA sequences and with the HSV alpha-trans-activator protein.

1990 • 227 citations

A common octamer motif binding protein is involved in the transcription of U6 snRNA by RNA polymerase III and U2 snRNA by RNA polymerase II

1987 • 224 citations

Purification and analysis of RNA polymerase II transcription factors by using wheat germ agglutinin affinity chromatography.

1989 • 175 citations

Direct combinatorial interaction between a herpes simplex virus regulatory protein and a cellular octamer-binding factor mediates specific induction of virus immediate-early gene expression.

1988 • 157 citations

The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2.

1990 • 91 citations

Differential regulation of octamer-containing cellular genes by the herpes simplex virus virion protein Vmw65 is mediated by sequence differences in the octamer element.

1988 • 25 citations

In vitro transcription faithfully reflecting T-cell activation requirements.

1992 • 20 citations