One Nucleotide in a κB Site Can Determine Cofactor Specificity for NF-κB Dimers

Toll-Like Receptors

2003 • 6,127 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

2003 • 3,104 citations

NF-κB in cancer: from innocent bystander to major culprit

2002 • 2,457 citations

Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors

2002 • 2,019 citations

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1995 • 1,849 citations

Toll-like Receptor Signaling

2003 • 1,503 citations

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

1990 • 1,377 citations

Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

1995 • 1,184 citations

Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome

1995 • 994 citations

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4

2002 • 985 citations

IRF3 Mediates a TLR3/TLR4-Specific Antiviral Gene Program

2002 • 844 citations

Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

1997 • 725 citations

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5

2002 • 709 citations

Toll-like Receptor 2 (TLR2) and TLR4 Differentially Activate Human Dendritic Cells

2001 • 693 citations

NF-kappa B activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

1999 • 554 citations

The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

2000 • 550 citations

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

2003 • 524 citations

Selection of Optimal κB/Rel DNA-Binding Motifs: Interaction of Both Subunits of NF-κB with DNA Is Required for Transcriptional Activation

1992 • 501 citations

Allosteric effects of DNA on transcriptional regulators

1998 • 488 citations

A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.

1993 • 480 citations

Transcriptional Activation by NF-κB Requires Multiple Coactivators

1999 • 433 citations

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers.

1993 • 416 citations

Two Waves of Nuclear Factor κb Recruitment to Target Promoters

2001 • 386 citations

Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B.

1992 • 373 citations

Genetic analysis of NF- B/Rel transcription factors defines functional specificities

2003 • 326 citations

The candidate oncoprotein Bcl-3 is an antagonist of pSO/NF-κB-mediated inhibition

1992 • 325 citations

A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells

1990 • 313 citations

Regulation of DNA binding by Rel/NF-κB transcription factors: structural views

1999 • 298 citations

Modulation of NF-κB Activity by Exchange of Dimers

2003 • 297 citations

Reversal of intrinsic DNA bends in the IFNβ gene enhancer by transcription factors and the architectural protein HMG I(Y)

1995 • 280 citations

c-Myc target gene specificity is determined by a post-DNAbinding mechanism

1998 • 280 citations

Essential role of IRF-3 in lipopolysaccharide-induced interferon-β gene expression and endotoxin shock

2003 • 266 citations

Chemokine Secretion of Rheumatoid Arthritis Synovial Fibroblasts Stimulated by Toll-Like Receptor 2 Ligands

2004 • 252 citations

The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha.

1995 • 245 citations

Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor

2003 • 244 citations

Cooperative interaction between interferon (IFN) stimulus response element and kappa B sequence motifs controls IFN gamma- and lipopolysaccharide-stimulated transcription from the murine IP-10 promoter.

1993 • 242 citations

An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation.

1994 • 238 citations

The virtuoso of versatility: POU proteins that flex to fit 1 1Edited by P. Wright

2000 • 224 citations

Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

2002 • 223 citations

Regulation of the Th2 Cytokine Locus by a Locus Control Region

2003 • 222 citations

Sequential MyD88-Independent and -Dependent Activation of Innate Immune Responses to Intracellular Bacterial Infection

2003 • 207 citations

A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation.

1996 • 182 citations

Deletion of the Igκ Light Chain Intronic Enhancer/Matrix Attachment Region Impairs but Does Not Abolish VκJκ Rearrangement

1996 • 172 citations

Retinoid X receptor and its partners in the nuclear receptor family

2001 • 170 citations

Coexamination of Site-Specific Transcription Factor Binding and Promoter Activity in Living Cells

1999 • 167 citations

Identification of the rel Family Members Required for Virus Induction of the Human Beta Interferon Gene

1995 • 142 citations

New Computational Approaches for Analysis of cis-Regulatory Networks

2002 • 116 citations

Interferon Regulatory Factor-3-mediated Activation of the Interferon-sensitive Response Element by Toll-like receptor (TLR) 4 but Not TLR3 Requires the p65 Subunit of NF-κ

2003 • 113 citations

Nuclear factor-kappa B p65 mediates the assembly and activation of the TNF-responsive element of the murine monocyte chemoattractant-1 gene.

1999 • 112 citations

The X-ray Crystal Structure of the NF-κB p50·p65 Heterodimer Bound to the Interferon β-κB Site

2002 • 112 citations

Nuclear Factor-κB p65 Mediates the Assembly and Activation of the TNF-Responsive Element of the Murine Monocyte Chemoattractant-1 Gene

1999 • 93 citations

The κB DNA Sequence from the HIV Long Terminal Repeat Functions as an Allosteric Regulator of HIV Transcription

2002 • 85 citations

Structure of NF-κB p50/p65 Heterodimer Bound to the PRDII DNA Element from the Interferon-β Promoter

2002 • 71 citations

An Interaction between the DNA-Binding Domains of RelA(p65) and Sp1 Mediates Human Immunodeficiency Virus Gene Activation

1994 • 55 citations