Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer

1997 • 1,655 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1997 • 1,300 citations

Regulation of Transcription by a Protein Methyltransferase

1999 • 1,169 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

1997 • 945 citations

Structure and specificity of nuclear receptor–coactivator interactions

1998 • 922 citations

Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

2002 • 787 citations

Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12

2000 • 720 citations

GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

1996 • 702 citations

Partial Hormone Resistance in Mice with Disruption of the Steroid Receptor Coactivator-1 (SRC-1) Gene

1998 • 685 citations

Atomic structure of progesterone complexed with its receptor

1998 • 654 citations

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2

1997 • 585 citations

A vector for expressing GAL4(1–147) fusions tn mammalian cells

1989 • 558 citations

The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

2000 • 550 citations

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

2000 • 531 citations

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

1998 • 516 citations

Allosteric effects of DNA on transcriptional regulators

1998 • 488 citations

The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.

1996 • 453 citations

Increasing the Complexity of Coactivation in Nuclear Receptor Signaling

1999 • 449 citations

Nuclear Receptor-Binding Sites of Coactivators Glucocorticoid Receptor Interacting Protein 1 (GRIP1) and Steroid Receptor Coactivator 1 (SRC-1): Multiple Motifs with Different Binding Specificities

1998 • 417 citations

Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells

2000 • 367 citations

Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

2000 • 319 citations

Ikappa Balpha -independent downregulation of NF-kappa B activity by glucocorticoid receptor

1997 • 298 citations

Transcriptional Repression by Nuclear Hormone Receptors

2000 • 291 citations

Steroid receptor induction of gene transcription: A two-step model

1997 • 269 citations

Glucocorticoid Receptor-Mediated Cell Cycle Arrest Is Achieved through Distinct Cell-Specific Transcriptional Regulatory Mechanisms

1997 • 266 citations

Multiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins

1999 • 262 citations

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator Activity by IκB Kinase

2002 • 260 citations

Mice deficient in the steroid receptor co-activator 1(SRC-1) are resistant to thyroid hormone

1999 • 255 citations

The Function of TIF2/GRIP1 in Mouse Reproduction Is Distinct from Those of SRC-1 and p/CIP

2002 • 253 citations

Synergistic, p160 Coactivator-dependent Enhancement of Estrogen Receptor Function by CARM1 and p300

2000 • 238 citations

Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter

2001 • 220 citations

Estradiol repression of tumor necrosis factor-α transcription requires estrogen receptor activation function-2 and is enhanced by coactivators

1999 • 196 citations

p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis

2000 • 192 citations

Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones

2001 • 168 citations

Mad Proteins Contain a Dominant Transcription Repression Domain

1996 • 163 citations

The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation.

1991 • 163 citations

A New Function for the C-terminal Zinc Finger of the Glucocorticoid Receptor

1997 • 153 citations

Phosphorylation and Inhibition of Rat Glucocorticoid Receptor Transcriptional Activation by Glycogen Synthase Kinase-3 (GSK-3)

1998 • 137 citations

Three Amino Acid Substitutions Selectively Disrupt the Activation but Not the Repression Function of the Glucocorticoid Receptor N Terminus

1997 • 116 citations

Glucocorticoid-Dependent Transcriptional Repression of the Osteocalcin Gene by Competitive Binding at the TATA Box

1997 • 78 citations

Tri-iodothyronine regulates the production of interleukin-6 and interleukin-8 in human bone marrow stromal and osteoblast-like cells

1998 • 77 citations

Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor α-regulated gene expression

1999 • 75 citations

Building Transcriptional Regulatory Complexes: Signals and Surfaces

1998 • 73 citations

Dexamethasone regulates IL-1? and TNF-?-induced interleukin-8 production in human bone marrow stromal and osteoblast-like cells

1994 • 49 citations

The Glucocorticoid Receptor Binds to a Sequence Overlapping the TATA Box of the Human Osteocalcin Promoter: a Potential Mechanism for Negative Regulation

1991 • 43 citations