Compensation of BRG-1 Function by Brm

Cancer Cell Cycles

1996 • 5,379 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

The regulation of E2F by pRB-family proteins

1998 • 2,297 citations

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

1998 • 1,472 citations

Retinoblastoma protein recruits histone deacetylase to repress transcription

1998 • 1,231 citations

The Rb/E2F pathway: expanding roles and emerging paradigms

2000 • 1,125 citations

Rb Interacts with Histone Deacetylase to Repress Transcription

1998 • 965 citations

Mechanisms of resistance to cisplatin

2001 • 849 citations

A Brg1 Null Mutation in the Mouse Reveals Functional Differences among Mammalian SWI/SNF Complexes

2000 • 811 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

1999 • 705 citations

Diversity and specialization of mammalian SWI/SNF complexes.

1996 • 703 citations

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

1993 • 668 citations

Exit from G1 and S Phase of the Cell Cycle Is Regulated by Repressor Complexes Containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

2000 • 650 citations

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1994 • 625 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

Cisplatin: From DNA damage to cancer chemotherapy

2001 • 595 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

BRCA1 Is Associated with a Human SWI/SNF-Related Complex

2000 • 548 citations

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

1995 • 515 citations

Rb function in cell-cycle regulation and apoptosis

2000 • 511 citations

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

1998 • 507 citations

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2–Cyclin A

1999 • 476 citations

Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α)

1998 • 421 citations

Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

2000 • 413 citations

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

2000 • 394 citations

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

1999 • 394 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines.

2000 • 357 citations

The Isw2 Chromatin Remodeling Complex Represses Early Meiotic Genes upon Recruitment by Ume6p

2000 • 307 citations

Disruption of Ini1 Leads to Peri-Implantation Lethality and Tumorigenesis in Mice

2001 • 292 citations

Histone Octamer Transfer by a Chromatin-Remodeling Complex

1999 • 290 citations

The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4

2001 • 287 citations

Human SWI/SNF Interconverts a Nucleosome between Its Base State and a Stable Remodeled State

1998 • 283 citations

Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors.

1997 • 273 citations

The Retinoblastoma Protein Pathway in Cell Cycle Control and Cancer

1997 • 264 citations

Role of the retinoblastoma protein in the pathogenesis of human cancer.

1997 • 256 citations

Functional Interactions between the hBRM/hBRG1 Transcriptional Activators and the pRB Family of Proteins

1996 • 252 citations

BRG-1 is required for RB-mediated cell cycle arrest

2000 • 245 citations

pRB plays an essential role in cell cycle arrest induced by DNA damage

1998 • 238 citations

Inactivation of p16 in Human Mammary Epithelial Cells by CpG Island Methylation

1998 • 231 citations

RB-Dependent S-Phase Response to DNA Damage

2000 • 224 citations

BRG-1 Is Recruited to Estrogen-Responsive Promoters and Cooperates with Factors Involved in Histone Acetylation

2000 • 221 citations

Control of the G1/S transition.

1997 • 219 citations

The Petinoblastoma Tumor Suppressor Protein

1994 • 215 citations

Multiple G1 Regulatory Elements Control the Androgen-dependent Proliferation of Prostatic Carcinoma Cells

1998 • 197 citations

When the SWI/SNF complex remodels … the cell cycle

2001 • 196 citations

Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies

2001 • 165 citations

Role of Human Cytomegalovirus Immediate-Early Proteins in Cell Growth Control

2000 • 118 citations

ras transformation is associated with decreased expression of the brm/SNF2alpha ATPase from the mammalian SWI-SNF complex

1998 • 103 citations

Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC

1999 • 93 citations

The BRG-1 Subunit of the SWI/SNF Complex Regulates CD44 Expression

2001 • 88 citations

Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors

1999 • 86 citations

CpG Methylation Inactivates the Transcriptional Activity of the Promoter of the Humanp53Tumor Suppressor Gene

1997 • 84 citations

Aberrations of the G1- and G1/S-regulating genes in human cancer

1997 • 83 citations

Restoration of retinoblastoma mediated signaling to Cdk2 results in cell cycle arrest

2000 • 77 citations

p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis

1999 • 73 citations

Cyclin A Is a Functional Target of Retinoblastoma Tumor Suppressor Protein-mediated Cell Cycle Arrest

1999 • 72 citations

The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death

1999 • 68 citations

Analysis of Site-Specific Phosphorylation of the Retinoblastoma Protein during Cell Cycle Progression

1999 • 33 citations

Corepressors and Retinoblastoma Protein Function

2001 • 25 citations