Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α)

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Cancer Cell Cycles

1996 • 5,379 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

Mice Lacking p27 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

1996 • 1,583 citations

Role of the INK4a Locus in Tumor Suppression and Cell Mortality

1996 • 1,580 citations

A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice

1996 • 1,488 citations

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

1998 • 1,472 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27

1996 • 1,283 citations

Rb Interacts with Histone Deacetylase to Repress Transcription

1998 • 965 citations

brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.

1995 • 926 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

p53 and E2F-1 cooperate to mediate apoptosis.

1994 • 844 citations

What's Up and Down with Histone Deacetylation and Transcription?

1997 • 831 citations

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

1996 • 830 citations

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.

1994 • 772 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

Diversity and specialization of mammalian SWI/SNF complexes.

1996 • 703 citations

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1995 • 681 citations

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

1993 • 668 citations

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1994 • 625 citations

Mice lacking vimentin develop and reproduce without an obvious phenotype

1994 • 603 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

Eukaryotic Transcription: An Interlaced Network of Transcription Factors and Chromatin-Modifying Machines

1998 • 561 citations

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

1992 • 535 citations

Binding and Stimulation of HIV-1 Integrase by a Human Homolog of Yeast Transcription Factor SNF5

1994 • 523 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila.

1988 • 460 citations

Repression and activation by multiprotein complexes that alter chromatin structure.

1996 • 444 citations

THE POLYCOMB AND TRITHORAX GROUP PROTEINS OF DROSOPHILA: Trans-Regulators of Homeotic Gene Function

1995 • 390 citations

The SWI-SNF complex: a chromatin remodeling machine?

1995 • 379 citations

Two human homologues ofSaccharomyces cerevisiae SWI2/SNF2andDrosophila brahmaare transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor

1994 • 338 citations

SWI2/SNF2 and Related Proteins: ATP-Driven Motors That Disrupt-Protein–DNA Interactions?

1997 • 301 citations

Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

1995 • 294 citations

RB and hbrm cooperate to repress the activation functions of E2F1

1997 • 293 citations

Human SWI/SNF Interconverts a Nucleosome between Its Base State and a Stable Remodeled State

1998 • 283 citations

The SNF/SWI family of global transcriptional activators

1994 • 269 citations

Functional Interactions between the hBRM/hBRG1 Transcriptional Activators and the pRB Family of Proteins

1996 • 252 citations

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

1996 • 228 citations

Components of the Human SWI/SNF Complex Are Enriched in Active Chromatin and Are Associated with the Nuclear Matrix

1997 • 226 citations

PcG complexes and chromatin silencing

1997 • 218 citations

Genetic Analysis of brahma: The Drosophila Homolog of the Yeast Chromatin Remodeling Factor SWI2/SNF2

1998 • 188 citations

A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor

1995 • 188 citations

Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes

1998 • 168 citations

SNF2β-BRG1 is Essential for the Viability of F9 Murine Embryonal Carcinoma Cells

1997 • 156 citations

A human protein with homology toSaccharomyces cerevisiaeSNF5 interacts with the potential helicase hbrm

1995 • 141 citations

The Yeast SWI-SNF Complex Facilitates Binding of a Transcriptional Activator to Nucleosomal Sites In Vivo

1997 • 139 citations

SNF11, a New Component of the Yeast SNF-SWI Complex That Interacts with a Conserved Region of SNF2

1995 • 125 citations

brg1: A Putative Murine Homologue of the Drosophila brahma Gene, a Homeotic Gene Regulator

1994 • 104 citations

ras transformation is associated with decreased expression of the brm/SNF2alpha ATPase from the mammalian SWI-SNF complex

1998 • 103 citations

Functional analysis of mouse Polycomb group genes

1998 • 81 citations

Hepatocyte Nuclear Factor 1α Gene Inactivation Impairs Chromatin Remodeling and Demethylation of the Phenylalanine Hydroxylase Gene

1997 • 75 citations

Activators and repressors: making use of chromatin to regulate transcription

1997 • 75 citations

Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein

1998 • 70 citations

p27KIP1, an inhibitor of cyclin-dependent kinases

1995 • 52 citations

A New Mouse Gene, SRG3, Related to the SWI3 of Saccharomyces cerevisiae, Is Required for Apoptosis Induced by Glucocorticoids in a Thymoma Cell Line

1997 • 48 citations

Protein complexes for remodeling chromatin

1997 • 34 citations