Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent

The language of covalent histone modifications

2000 • 8,260 citations

CELLULAR RESPONSES TO INTERFERON-γ

1997 • 2,885 citations

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 • 1,660 citations

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

1998 • 1,472 citations

The role of STATs in transcriptional control and their impact on cellular function

2000 • 1,186 citations

ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION

1998 • 1,124 citations

Regulation of MHC Class II Expression by Interferon-γ Mediated by the Transactivator Gene CIITA

1994 • 854 citations

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

1996 • 830 citations

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1993 • 828 citations

A Brg1 Null Mutation in the Mouse Reveals Functional Differences among Mammalian SWI/SNF Complexes

2000 • 811 citations

Ordered Recruitment of Chromatin Modifying and General Transcription Factors to the IFN-β Promoter

2000 • 716 citations

Diversity and specialization of mammalian SWI/SNF complexes.

1996 • 703 citations

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

1993 • 668 citations

Exit from G1 and S Phase of the Cell Cycle Is Regulated by Repressor Complexes Containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

2000 • 650 citations

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1994 • 625 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

The Bare Lymphocyte Syndrome and the Regulation of MHC Expression

2001 • 516 citations

Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA

1997 • 510 citations

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

1998 • 507 citations

Functional selectivity of recombinant mammalian SWI/SNF subunits

2000 • 503 citations

Two contact regions between Stat1 and CBP/p300 in interferon γ signaling

1996 • 486 citations

The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

2001 • 440 citations

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300

1997 • 428 citations

Constitutional Mutations of the hSNF5/INI1 Gene Predispose to a Variety of Cancers

1999 • 428 citations

Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

2000 • 413 citations

Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae

2000 • 398 citations

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

1999 • 394 citations

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

2000 • 394 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Activation of the MHC Class II Transactivator CIITA by Interferon-γ Requires Cooperative Interaction between Stat1 and USF-1

1998 • 358 citations

Mice Lacking the MHC Class II Transactivator (CIITA) Show Tissue-Specific Impairment of MHC Class II Expression

1996 • 356 citations

Regulation of CSF1 Promoter by the SWI/SNF-like BAF Complex

2001 • 340 citations

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation

2001 • 325 citations

A C/EBPβ Isoform Recruits the SWI/SNF Complex to Activate Myeloid Genes

1999 • 308 citations

Spectrum of hSNF5IINI1 Somatic Mutations in Human Cancer and Genotype-Phenotype Correlations

1999 • 308 citations

RB and hbrm cooperate to repress the activation functions of E2F1

1997 • 293 citations

Disruption of Ini1 Leads to Peri-Implantation Lethality and Tumorigenesis in Mice

2001 • 292 citations

The Structure, Regulation and Function of the Janus Kinases (JAKs) and the Signal Transducers and Activators of Transcription (STATs)

1997 • 285 citations

Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes

2001 • 278 citations

A Human RNA Polymerase II Complex Containing Factors That Modify Chromatin Structure

1998 • 277 citations

Chromatin remodeling enzymes: who's on first?

2001 • 265 citations

Mitotic inactivation of a human SWI/SNF chromatin remodeling complex

1998 • 257 citations

Activation Domain–Mediated Targeting of the SWI/SNF Complex to Promoters Stimulates Transcription from Nucleosome Arrays

1999 • 245 citations

BRG-1 is required for RB-mediated cell cycle arrest

2000 • 245 citations

Transcriptional Regulation of Mammalian Genes in Vivo

1997 • 244 citations

Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators

1999 • 234 citations

BRG-1 Is Recruited to Estrogen-Responsive Promoters and Cooperates with Factors Involved in Histone Acetylation

2000 • 221 citations

A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor

1995 • 188 citations

Two Distinct Gamma Interferon-Inducible Promoters of the Major Histocompatibility Complex Class II Transactivator Gene Are Differentially Regulated by STAT1, Interferon Regulatory Factor 1, and Transforming Growth Factor β

1999 • 184 citations

ATP-Driven Chromatin Remodeling Activity and Histone Acetyltransferases Act Sequentially during Transactivation by RAR/RXR In Vitro

2000 • 184 citations

Direct Transcriptional Repression by pRB and Its Reversal by Specific Cyclins

1995 • 179 citations

Factors associated with the mammalian RNA polymerase II holoenzyme

1998 • 167 citations

Mechanisms for ATP-dependent chromatin remodelling

2001 • 163 citations

IFN regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo.

1997 • 162 citations

Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene.

1998 • 156 citations

Mammalian SWI-SNF Complexes Contribute to Activation of the hsp70 Gene

2000 • 149 citations

Molecular analysis of G1B and G3A IFNγ mutants reveals that defects in CIITA or RFX result in defective class II MHC and li gene induction

1994 • 145 citations

INI1 mutations in meningiomas at a potential hotspot in exon 9

2001 • 133 citations

Human SWI-SNF Component BRG1 Represses Transcription of the c-fos Gene

1999 • 131 citations

Stat1 alpha expression is involved in IFN-gamma induction of the class II transactivator and class II MHC genes.

1996 • 125 citations

Transcriptional Activation Domains of Human Heat Shock Factor 1 Recruit Human SWI/SNF

2001 • 121 citations

IFN-γ Regulation of Class II Transactivator Promoter IV in Macrophages and Microglia: Involvement of the Suppressors of Cytokine Signaling-1 Protein

2001 • 104 citations

The mammalian SWI/SNF complex and the control of cell growth

1999 • 103 citations

Mice lacking the transcription factor CIITA--a second look.

1998 • 95 citations

IFN-gamma regulation of the type IV class II transactivator promoter in astrocytes.

1999 • 91 citations

Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae

2000 • 84 citations

The bromodomain: a regulator of ATP-dependent chromatin remodeling?

2001 • 82 citations

IFN-γ Regulation of the Type IV Class II Transactivator Promoter in Astrocytes

1999 • 72 citations

Cell‐based vaccines for the stimulation of immunity to metastatic cancers

1999 • 55 citations

Evidence for retinoblastoma protein (RB) dependent and independent IFN-gamma responses: RB coordinately rescues IFN-gamma induction of MHC class II gene transcription in noninducible breast carcinoma cells.

1994 • 55 citations

Co-occupancy of the interferon regulatory element of the class II transactivator (CIITA) Type IV promoter by interferon regulatory factors 1 and 2

1999 • 50 citations

hSNF5/INI1 gene mutations in lymphoid malignancy

2000 • 33 citations

pRB is required for interferon-γ-induction of the MHC class II Aβ gene

1999 • 26 citations

Impaired class II transactivator expression in mice lacking interferon regulatory factor-2

2001 • 20 citations

BRG-1 is required for RB-mediated cell cycle arrest

2000 • 5 citations

Mechanisms for ATP-dependent chromatin remodelling

2000 • 5 citations