Mammalian SWI-SNF Complexes Contribute to Activation of the hsp70 Gene

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

Current protocols in molecular biology

1988 • 4,543 citations

Histone acetylation and transcriptional regulatory mechanisms

1998 • 1,793 citations

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

1998 • 1,472 citations

Cells in Stress: Transcriptional Activation of Heat Shock Genes

1993 • 1,429 citations

Roles of histone acetyltransferases and deacetylases in gene regulation

1998 • 1,207 citations

Heat Shock Transcription Factors: Structure and Regulation

1995 • 1,179 citations

ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION

1998 • 1,124 citations

brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

NURD, a Novel Complex with Both ATP-Dependent Chromatin-Remodeling and Histone Deacetylase Activities

1998 • 946 citations

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

1988 • 886 citations

Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.

1993 • 879 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

1996 • 830 citations

The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities

1998 • 791 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

1999 • 705 citations

RSC, an Essential, Abundant Chromatin-Remodeling Complex

1996 • 680 citations

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

1993 • 668 citations

The RNA polymerase II molecule at the 5′ end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged

1988 • 662 citations

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

1994 • 662 citations

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

1998 • 655 citations

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1994 • 625 citations

ACF, an ISWI-Containing and ATP-Utilizing Chromatin Assembly and Remodeling Factor

1997 • 624 citations

Transcriptional regulation of the mouse metallothionein-I gene by heavy metals.

1981 • 601 citations

Purification and properties of an ATP-dependent nucleosome remodeling factor

1995 • 600 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

GENES AFFECTING THE REGULATION OF SUC2 GENE EXPRESSION BY GLUCOSE REPRESSION IN SACCHAROMYCES CEREVISIAE

1984 • 567 citations

Chromatin disruption and modification

1999 • 537 citations

Binding and Stimulation of HIV-1 Integrase by a Human Homolog of Yeast Transcription Factor SNF5

1994 • 523 citations

Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II

1997 • 511 citations

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

1998 • 507 citations

Protein traffic on the heat shock promoter: Parking, stalling, and trucking along

1993 • 507 citations

Heat shock factor is regulated differently in yeast and HeLa cells

1987 • 489 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Five SWI genes are required for expression of the HO gene in yeast

1984 • 450 citations

A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase

1998 • 426 citations

Transcriptional regulation of heat shock genes. A paradigm for inducible genomic responses.

1992 • 417 citations

Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement.

1994 • 410 citations

Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.

1988 • 407 citations

A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.

1994 • 396 citations

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

1999 • 394 citations

Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators

1987 • 392 citations

Glyceraldehyde-3-phosphate dehydrogenase mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte

1990 • 391 citations

Characterization of the Imitation Switch subfamily of ATP-dependent chromatin-remodeling factors in Saccharomyces cerevisiae

1999 • 386 citations

A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice.

1995 • 383 citations

ISWI, a member of the SWl2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor

1995 • 366 citations

Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development.

1990 • 342 citations

Two human homologues ofSaccharomyces cerevisiae SWI2/SNF2andDrosophila brahmaare transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor

1994 • 338 citations

A C/EBPβ Isoform Recruits the SWI/SNF Complex to Activate Myeloid Genes

1999 • 308 citations

Structure of mouse metallothionein-I gene and its mRNA

1981 • 301 citations

Requirement of RSF and FACT for Transcription of Chromatin Templates in Vitro

1998 • 298 citations

In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation.

1990 • 295 citations

RB and hbrm cooperate to repress the activation functions of E2F1

1997 • 293 citations

The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes

1998 • 287 citations

Activation in vitro of sequence-specific DNA binding by a human regulatory factor

1988 • 278 citations

Mitotic inactivation of a human SWI/SNF chromatin remodeling complex

1998 • 257 citations

Functional Interactions between the hBRM/hBRG1 Transcriptional Activators and the pRB Family of Proteins

1996 • 252 citations

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

1998 • 245 citations

Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing.

1991 • 239 citations

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

1996 • 228 citations

Factor-stimulated RNA polymerase II transcribes at physiological elongation rates on naked DNA but very poorly on chromatin templates.

1992 • 228 citations

Chromatin-modifying and -remodeling complexes

1999 • 217 citations

Glucocorticoid regulation of metallothionein-I mRNA synthesis in cultured mouse cells.

1981 • 211 citations

Activator-dependent regulation of transcriptional pausing on nucleosomal templates.

1996 • 205 citations

Identification and characterization of Drosophila relatives of the yeast transcriptional activator SNF2/SWI2.

1994 • 202 citations

Direct Sensing of Heat and Oxidation by Drosophila Heat Shock Transcription Factor

1998 • 200 citations

A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor

1995 • 188 citations

Characterization and sequence of a mouse hsp70 gene and its expression in mouse cell lines

1990 • 187 citations

Cyclin E Associates with BAF155 and BRG1, Components of the Mammalian SWI-SNF Complex, and Alters the Ability of BRG1 To Induce Growth Arrest

1999 • 163 citations

Isolation and characterization of the mouse heme oxygenase-1 gene. Distal 5' sequences are required for induction by heme or heavy metals.

1994 • 153 citations

Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF-SWI complex, hSNF5/Ini1

1996 • 142 citations

A human protein with homology toSaccharomyces cerevisiaeSNF5 interacts with the potential helicase hbrm

1995 • 141 citations

Complex modes of heat shock factor activation.

1990 • 141 citations

Transduction of the stress signal and mechanisms of transcriptional regulation of heat shock/stress protein gene expression in higher eukaryotes.

1994 • 133 citations

Human SWI-SNF Component BRG1 Represses Transcription of the c-fos Gene

1999 • 131 citations

Role of Nucleosome Remodeling Factor NURF in Transcriptional Activation of Chromatin

1997 • 129 citations

Interaction of E1 and hSNF5 proteins stimulates replication of human papillomavirus DNA

1999 • 125 citations

The SNF2, SNF5 and SNF6 genes are required for Ty transcription in Saccharomyces cerevisiae.

1991 • 97 citations

p300/CREB Binding Protein-Related Protein p270 Is a Component of Mammalian SWI/SNF Complexes

1998 • 90 citations

Transcriptional activation domains stimulate initiation and elongation at different times and via different residues

1998 • 76 citations

Regulation of heat shock factor in Schizosaccharomyces pombe more closely resembles regulation in mammals than in Saccharomyces cerevisiae.

1991 • 72 citations

Antibody-Mediated Activation of Drosophila Heat Shock Factor in Vitro

1990 • 70 citations

Disruption of downstream chromatin directed by a transcriptional activator

1997 • 65 citations

Energy-Dependent Chromatin Remodelers: Complex Complexes and Their Components

1998 • 53 citations

The GAM1/SNF2 gene of Saccharomyces cerevisiae encodes a highly charged nuclear protein required for transcription of the STA1 gene

1991 • 51 citations

Complex Modes of Heat Shock Factor Activation

1990 • 47 citations

Characterization of trans-acting mutations affecting Ty and Ty-mediated transcription in Saccharomyces cerevisiae

1991 • 47 citations

Adenovirus E1A Specifically Blocks SWI/SNF-Dependent Transcriptional Activation

1996 • 32 citations

The SNF2/SWI2/GAM1/TYE3/RIC1 Gene Is Involved in the Coordinate Regulation of Phospholipid Synthesis in Saccharomyces cerevisiae

1995 • 26 citations

Differences in preferential synthesis and redistribution of HSP70 and HSP28 families by heat or sodium arsenite in chinese hamster ovary cells

1991 • 25 citations

Mutations in the Schizosaccharomyces pombe heat shock factor that differentially affect responses to heat and cadmium stress

1999 • 22 citations

Isolation of the TYE2 gene reveals its identity to SW13 encoding a general transcription factor in Saccharomyces cerevisiae

1993 • 8 citations