F‐actin‐based Ca signaling—a critical comparison with the current concept of Ca signaling

Molecular and cellular physiology of intracellular calcium stores

1994 • 1,132 citations

Ryanodine Receptor Calcium Release Channels

2002 • 1,060 citations

Actin Depolymerizing Factor (ADF/Cofilin) Enhances the Rate of Filament Turnover: Implication in Actin-based Motility

1997 • 1,028 citations

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

1993 • 892 citations

Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells

1989 • 887 citations

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

1985 • 824 citations

Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin.

1994 • 798 citations

Cofilin Changes the Twist of F-Actin: Implications for Actin Filament Dynamics and Cellular Function

1997 • 747 citations

Latrunculins—novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D

1989 • 566 citations

Mechanisms of capacitative calcium entry

2001 • 536 citations

Store-Operated Ca2+ Entry

1999 • 433 citations

Effects of cytochalasin, phalloidin and pH on the elongation of actin filaments

1991 • 329 citations

Hormone-evoked calcium release from intracellular stores is a quantal process

1989 • 312 citations

Cofilin, a protein in porcine brain that binds to actin filaments and inhibits their interactions with myosin and tropomyosin

1984 • 312 citations

An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal

2004 • 308 citations

Highly Cooperative Opening of Calcium Channels by Inositol 1,4,5-Trisphosphate

1988 • 307 citations

The thiol reagent, thimerosal, evokes Ca2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor.

1992 • 269 citations

Tropomyosin inhibits ADF/cofilin-dependent actin filament dynamics

2002 • 242 citations

The architecture of actin filaments and the ultrastructural location of actin-binding protein in the periphery of lung macrophages.

1986 • 196 citations

Kinetic Analysis of the Interaction of Actin-depolymerizing Factor (ADF)/Cofilin with G- and F-Actins

1998 • 194 citations

Calcium and polyphosphoinositide control of cytoskeletal dynamics

1989 • 168 citations

The Psychological Maltreatment Inventory: Development of a Measure of Psychological Maltreatment in Childhood for Use in Adult Clinical Settings

1994 • 145 citations

Detection of Ca2+ entry through mechanosensitive channels localizes the site of mechanoelectrical transduction in hair cells.

1995 • 144 citations

Sensitization of Calcium-induced Calcium Release by Cyclic ADP-ribose and Calmodulin

1995 • 144 citations

Translocation of ATP into the lumen of rough endoplasmic reticulum-derived vesicles and its binding to luminal proteins including BiP (GRP 78) and GRP 94.

1992 • 131 citations

F-actin disruption attenuates agonist-induced [Ca2+], myosin phosphorylation, and force in smooth muscle

1997 • 129 citations

Inositol 1,4,5 trisphosphate releases calcium from specialized sites within Limulus photoreceptors

1987 • 113 citations

Cellular target of weak magnetic fields: ionic conduction along actin filaments of microvilli

2002 • 108 citations

Amino Acid-stimulated Ca2+ Oscillations Produced by the Ca2+-sensing Receptor Are Mediated by a Phospholipase C/Inositol 1,4,5-Trisphosphate-independent Pathway That Requires G12, Rho, Filamin-A, and the Actin Cytoskeleton

2005 • 99 citations

Cooperativity in F-Actin: Binding of Gelsolin at the Barbed End Affects Structure and Dynamics of the Whole Filament

1996 • 98 citations

Transient Kinetic Analysis of the 130-kDa Myosin I (MYR-1 Gene Product) from Rat Liver

1999 • 95 citations

A morphological study of differentiated hepatocytesin vitro

1995 • 94 citations

The Mammalian Sec6/8 Complex Interacts with Ca2+ Signaling Complexes and Regulates Their Activity

2000 • 93 citations

Oscillatory CaMKII activity in mouse egg activation

2003 • 91 citations

Endoplasmic reticulum calcium release is modulated by actin polymerization

2002 • 90 citations

Calcium-calmodulin and regulation of brush border myosin-I MgATPase and mechanochemistry

1993 • 86 citations

The Bell-shaped Ca2+ Dependence of the Inositol 1,4,5-Trisphosphate-induced Ca2+ Release Is Modulated by Ca2+/Calmodulin

1999 • 85 citations

Ca2+ Regulation of Gelsolin Activity: Binding and Severing of F-actin

1998 • 85 citations

In Vitro Activity Differences between Proteins of the ADF/Cofilin Family Define Two Distinct Subgroups

2004 • 83 citations

Filament Assembly from Profilin-Actin

1999 • 83 citations

Voltage-dependent InsP3- insensitive calcium channels in membranes of pancreatic endoplasmic reticulum vesicles

1990 • 80 citations

An essential role of myosin light‐chain kinase in the regulation of agonist‐ and fluid flow‐stimulated Ca²⁺influx in endothelial cells

1998 • 78 citations

Store-operated calcium entry and increased endothelial cell permeability

2000 • 73 citations

Control of Actin Filament Length and Turnover by Actin Depolymerizing Factor (ADF/Cofilin) in the Presence of Capping Proteins and ARP2/3 Complex

1999 • 72 citations

Hyperosmotically Induced Volume Change and Calcium Signaling in Intervertebral Disk Cells: The Role of the Actin Cytoskeleton

2002 • 71 citations

High affinity binding of divalent cation to actin monomer is much stronger than previously reported

1986 • 70 citations

Microvillar Ca++ signaling: A new view of an old problem

1999 • 69 citations

Phasic characteristic of elementary Ca²⁺release sites underlies quantal responses to IP₃

2000 • 68 citations

A Calcium Signaling Cascade Essential for Myosin Thick Filament Assembly in Xenopus Myocytes

1998 • 67 citations

Ca2+ stimulates the Mg2(+)-ATPase activity of brush border myosin I with three or four calmodulin light chains but inhibits with less than two bound.

1991 • 67 citations

Plasma Membrane Ca2+ Release-Activated Ca2+ Channels With A High Selectivity for Ca2+ Identified by Patch–Clamp Recording in Rat Liver Cells

2001 • 66 citations

Differential modulation of inositol 1,4,5-trisphosphate receptor type 1 and type 3 by ATP

2000 • 61 citations

Mechanosensitive Ca ²⁺ oscillations and STOC activation in endothelial cells

1998 • 60 citations

Live dynamics of GFP-calponin: isoform-specific modulation of the actin cytoskeleton and autoregulation by C-terminal sequences

2000 • 59 citations

cAMP-induced Cytoskeleton Rearrangement Increases Calcium Transients through the Enhancement of Capacitative Calcium Entry

1999 • 58 citations

Motility of myosin V regulated by the dissociation of single calmodulin

2005 • 58 citations

Role of microvillar cell surfaces in the regulation of glucose uptake and organization of energy metabolism

2002 • 58 citations

Inhibition of Agonist-Induced Ca2+Entry in Endothelial Cells by Myosin Light-Chain Kinase Inhibitor

1996 • 57 citations

Behavior of divalent cations and nucleotides bound to F-actin

1969 • 55 citations

Disruption of actin cytoskeleton in cultured rat astrocytes suppresses ATP- and bradykinin-induced [Ca2+]i oscillations by reducing the coupling efficiency between Ca2+ release, capacitative Ca2+ entry, and store refilling

2000 • 55 citations

Calcium storage and release properties of F‐actin: evidence for the involvement of F‐actin in cellular calcium signaling

1996 • 52 citations

Receptor-dependent activation of store-operated calcium entry increases endothelial cell permeability

2000 • 52 citations

Tropomyosin and Gelsolin Cooperate in Controlling the Microfilament System

2002 • 51 citations

Activation of oocytes by latrunculin A

2002 • 49 citations

Rac Is Involved in Early TCR Signaling

2000 • 49 citations

Calponin induces actin polymerization at low ionic strength and inhibits depolymerization of actin filaments

1995 • 47 citations

Regulation of cell volume via microvillar ion channels

2000 • 46 citations

The M-phase-promoting Factor Modulates the Sensitivity of the Ca2+ Stores to Inositol 1,4,5-Trisphosphate via the Actin Cytoskeleton

2003 • 45 citations

Binding of Divalent Cation and Nucleotide to G-actin in the Presence of Profilin

1995 • 44 citations

Highly Supralinear Feedback Inhibition of Ca2+ Uptake by the Ca2+ Load of Intracellular Stores

1996 • 44 citations

Mechanisms underlying InsP₃‐evoked global Ca²⁺ signals in mouse pancreatic acinar cells

2000 • 44 citations

Calmodulin regulates the disassembly of cortical F-actin in mast cells but is not required for secretion

2000 • 43 citations

Microvillar Ion Channels: Cytoskeletal Modulation of Ion Fluxes

2000 • 40 citations

Maintenance of the filamentous actin cytoskeleton is necessary for the activation of store-operated Ca2+ channels, but not other types of plasma-membrane Ca2+ channels, in rat hepatocytes

2002 • 39 citations

Functionally distinct pools of actin in secretory cells

2001 • 38 citations

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells

2005 • 38 citations

The actin cytoskeleton and cytotoxic T lymphocytes: evidence for multiple roles that could affect granule exocytosis-dependent target cell killing

2003 • 38 citations

Ryanodine receptor expression is associated with intracellular Ca²⁺ release in rat parotid acinar cells

1997 • 37 citations

Stimulus-dependent Disorganization of Actin Filaments Induced by Overexpression of Cofilin in C2 Myoblasts.

1996 • 37 citations

Use of intracellular calcium stores from rat basophilic leukemia cells to study the molecular mechanism leading to quantal calcium release by inositol 1,4,5-trisphosphate

1993 • 37 citations

Myosin Light Chain Kinase Regulates Capacitative Ca ²⁺ Entry in Human Monocytes/Macrophages

2001 • 36 citations

Characterization of Ca2+/calmodulin-dependent protein kinase I as a myosin II regulatory light chain kinase in vitro and in vivo

2002 • 35 citations

2,3-Butanedione monoxime (BDM) decreases sarcoplasmic reticulum Ca content by stimulating Ca release in isolated rat ventricular myocytes

1998 • 33 citations

Direct inhibition of chicken gizzard smooth muscle contractile apparatus by caffeine

1990 • 33 citations

Calmodulin Increases the Sensitivity of Type 3 Inositol-1,4,5-trisphosphate Receptors to Ca²⁺Inhibition in Human Bronchial Mucosal Cells

2000 • 32 citations

Store-operated Ca2+ inflow in Reuber hepatoma cells is inhibited by voltage-operated Ca2+ channel antagonists and, in contrast to freshly isolated hepatocytes, does not require a pertussis toxin-sensitive trimeric GTP-binding protein

2000 • 32 citations

Evidence for a vesicle-mediated maintenance of store-operated calcium channels in a human embryonic kidney cell line

2000 • 31 citations

Calmodulin inhibits calcium influx current in vascular endothelium

1996 • 31 citations

Effects of 2,3-butanedione monoxime on sarcoplasmic reticulum of saponin-treated rat cardiac muscle

1993 • 31 citations

Chlorpromazine inhibits store‐operated calcium entry and subsequent noradrenaline secretion in PC12 cells

2001 • 30 citations

Insulin‐responsive glucose transporters are concentrated in a cell surfacederived membrane fraction of 3T3‐L1 adipocytes

1990 • 30 citations

The IP3‐sensitive calcium store of HIT cells is located in a surface‐derived vesicle fraction

1993 • 29 citations

Effects of Muscle Proteins on the Interaction between Actin and an Actin-Depolymerizing Protein from Starfish Oocytes1

1982 • 28 citations

Action of Insulin on the Surface Morphology of Hepatocytes: Role of Phosphatidylinositol 3-kinase in Insulin-Induced Shape Change of Microvilli

1998 • 27 citations

Maintenance of the filamentous actin cytoskeleton is necessary for the activation of store-operated Ca2+ channels, but not other types of plasma-membrane Ca2+ channels, in rat hepatocytes

2002 • 26 citations

Microvillar cell surface as a natural defense system against xenobiotics: a new interpretation of multidrug resistance

2001 • 25 citations

Activation of Calcium Signaling in Isolated Rat Hepatocytes Is Accompanied by Shape Changes of Microvilli

1997 • 25 citations

Conversion of ATP‐actin to ADP‐actin reverses the affinity of monomeric actin for Ca²⁺ vs Mg²⁺

1987 • 25 citations

Inhibition of the type 1 inositol 1,4,5-trisphosphate-sensitive Ca2+ channel by calmodulin antagonists

2001 • 25 citations

Increased Cytosolic Ca2+ Concentration in Endothelial Cells by Calmodulin Antagonists

1999 • 24 citations

Inhibitors of actin polymerisation stimulate arachidonic acid release and 5-lipoxygenase activation by upregulation of Ca2+ mobilisation in polymorphonuclear leukocytes involving Src family kinases

2005 • 24 citations

Myosin light chain phosphorylation during the contraction cycle of frog muscle.

1980 • 20 citations

Cell surface characteristics of proadipocytes growth arrested at the predifferentiation GD state. Defects associated with neoplastic transformation.

1983 • 20 citations

Hypotonic Ca2+ signaling and volume regulation in proliferating and quiescent cells from multicellular spheroids

1998 • 18 citations

Ca2+ mobilization induced by W-7 in MG63 human osteosarcoma cells

2000 • 18 citations

A Novel Ca2+-induced Ca2+ Release Mechanism in A7r5 Cells Regulated by Calmodulin-like Proteins

2003 • 18 citations

Histone acetylation in conjugating Tetrahymena thermophila [published erratum appears in J Cell Biol 1989 Dec;109(6 Pt 1):3214-7]

1989 • 18 citations

Rapid uptake of calcium, ATP, and inositol 1,4,5‐trisphosphate via cation and anion channels into surface‐derived vesicles from HIT cells containing the inositol 1,4,5‐trisphosphate‐sensitive calcium store

1993 • 18 citations

Dephosphorylation of Calponin by Type 2B Protein Phosphatase

1995 • 18 citations

Functional overlap of IP₃- and cADP-ribose-sensitive calcium stores in guinea pig myenteric neurons

2001 • 15 citations

Kinetics of Myosin Subfragment-1-Induced Condensation of G-Actin into Oligomers, Precursors in the Assembly of F-Actin−S₁. Role of the Tightly Bound Metal Ion and ATP Hydrolysis

1997 • 15 citations

Detection of the ATP-Dependent Nonmitochondrial Calcium Store in a Cell Surface-Derived Vesicle Fraction from Isolated Rat Hepatocytes

1996 • 15 citations

Involvement of calmodulin in the activation of store‐operated Ca²⁺ entry in rat hepatocytes

1998 • 14 citations

Acute actions of marine toxin latrunculin A on the electrophysiological properties of cultured dorsal root ganglion neurones

2005 • 14 citations

Integrity of Actin-Network Is Involved in Uridine 5'-Triphosphate Evoked Store-Operated Ca2+ Entry in Bovine Adrenocortical Fasciculata Cells

2003 • 13 citations

Intracellular Mg2+ movement during muscarinic stimulation. Mg2+ uptake by the intracellular Ca2+ store in rat sublingual mucous acini.

1994 • 13 citations

Mechanotransduction in Colonic Smooth Muscle Cells

1997 • 12 citations

Does Actin Polymerization Status Modulate Ca2+Storage in Human Neutrophils? Release and Coalescence of Ca2+Stores by Cytochalasins

1997 • 11 citations

Ca2+/Calmodulin Inhibition and Phospholipase C-Linked Ca2+ Signaling in Clonalβ -Cells1

1999 • 11 citations

Mechanism of Myosin Subfragment-1-Induced Assembly of CaG-Actin and MgG-Actin into F-Actin−S₁-Decorated Filaments

1997 • 11 citations

The Calmodulin Antagonist W-7 Depletes Intracellular Calcium Stores in FRTL-5 Thyroid Cells

1993 • 10 citations

F-actin does not modulate the initial steps of the protein kinase C activation process in living nerve cells

2003 • 10 citations

Modulation of Ca2+channel-gated Ca2+release by W-7 in cardiac myocytes

1999 • 9 citations

Extracellular compartments of the blowfly eye: Ionic content and topology

1999 • 8 citations

Interactions between intracellular Ca2+ stores: Ca2+ released from the NAADP pool potentiates cADPR-induced Ca2+ release

2002 • 7 citations

The actin cytoskeleton and cytotoxic T lymphocytes: evidence for multiple roles that could affect granule exocytosis-dependent target cell killing

2003 • 7 citations

Modulation of IP3-sensitive Ca2+ release by 2,3-butanedione monoxime

2002 • 7 citations

Bidirectional Activity of the Endoplasmic Reticulum Ca2+-ATPase of Bovine Adrenal Cortex

1995 • 4 citations

Calcium stores in electropermeabilized HL-60 cells before and after differentiation

1991 • 4 citations

Deleted Work

1955 • 0 citations