A Calcium Signaling Cascade Essential for Myosin Thick Filament Assembly in Xenopus Myocytes

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

1980 • 2,218 citations

Signal transduction and regulation in smooth muscle

1994 • 1,915 citations

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1997 • 1,533 citations

Titins: Giant Proteins in Charge of Muscle Ultrastructure and Elasticity

1995 • 1,195 citations

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

1990 • 1,061 citations

Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum.

1986 • 710 citations

Structure and function of ryanodine receptors

1994 • 617 citations

Calcium regulation of the neuronal growth cone

1988 • 581 citations

Distinct aspects of neuronal differentiation encoded by frequency of spontaneous Ca2+ transients

1995 • 537 citations

Regulation of non-muscle myosin assembly by calmodulin-dependent light chain kinase

1980 • 338 citations

An elevated free cytosolic Ca2+ wave follows fertilization in eggs of the frog, Xenopus laevis.

1985 • 336 citations

The premyofibril: Evidence for its role in myofibrillogenesis

1994 • 328 citations

Redundant Mechanisms of Calcium-Induced Calcium Release Underlying Calcium Waves During Fertilization of Sea Urchin Eggs

1993 • 313 citations

Action Potential-Dependent Regulation of Gene Expression: Temporal Specificity in Ca²⁺, cAMP-Responsive Element Binding Proteins, and Mitogen-Activated Protein Kinase Signaling

1997 • 304 citations

The development of the action potential mechanism of amphibian neurons isolated in culture.

1976 • 257 citations

Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase.

1984 • 249 citations

Spontaneous neuronal calcium spikes and waves during early differentiation

1994 • 248 citations

Myosin light chain kinases.

1997 • 247 citations

Myosin light chain phosphorylation affects the structure of rabbit skeletal muscle thick filaments

1996 • 215 citations

Getting hydrophilic compounds into cells: lessons from homeopeptides

1996 • 194 citations

Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse

1995 • 148 citations

Breaking the Code: Regulation of Neuronal Differentiation by Spontaneous Calcium Transients

1997 • 147 citations

Molecular Analysis of Protein Assembly in Muscle Development

1991 • 143 citations

Characterization of spontaneous calcium transients in nerve growth cones and their effect on growth cone migration

1995 • 141 citations

Production and characterization of an antibody to myosin light chain kinase and intracellular localization of the enzyme

1981 • 137 citations

Abnormal junctions between surface membrane and sarcoplasmic reticulum in skeletal muscle with a mutation targeted to the ryanodine receptor.

1995 • 128 citations

Structural Basis of the Intrasteric Regulation of Myosin Light Chain Kinases

1992 • 117 citations

Changes in synaptic potential properties during acetylcholine receptor accumulation and neurospecific interactions in Xenopus nerve-muscle cell culture

1980 • 116 citations

Role of myosin light chains

1994 • 107 citations

Development of the Excitation-Contraction Coupling Apparatus in Skeletal Muscle: Association of Sarcoplasmic Reticulum and Transverse Tubules with Myofibrils

1993 • 105 citations

Localized Calcium Transients Accompany Furrow Positioning, Propagation, and Deepening during the Early Cleavage Period of Zebrafish Embryos

1997 • 105 citations

Characterization of antibodies to smooth muscle myosin kinase and their use in localizing myosin kinase in nonmuscle cells.

1981 • 89 citations

Calcium waves along the cleavage furrows in cleavage-stage Xenopus embryos and its inhibition by heparin.

1996 • 81 citations

Localized Calcium Signals in Early Zebrafish Development

1995 • 71 citations

Single-cell transplantation determines the time when Xenopus muscle precursor cells acquire a capacity for autonomous differentiation.

1993 • 70 citations

Spontaneous Calcium Transients Regulate Myofibrillogenesis in EmbryonicXenopusMyocytes

1996 • 67 citations

Expression of a Novel Myosin Light Chain Kinase in Embryonic Tissues and Cultured Cells

1995 • 61 citations

Development of the excitation-contraction coupling apparatus in skeletal muscle: peripheral and internal calcium release units are formed sequentially

1994 • 52 citations

Domain characterization of rabbit skeletal muscle myosin light chain kinase.

1990 • 52 citations

Early cross-striation formation in twitching Xenopus myocytes in culture.

1988 • 46 citations

Ryanodine receptor protein is expressed during differentiation in the muscle cell lines BC3H1 and C2C12

1991 • 45 citations

Imaging Calcium Waves in Eggs and Embryos

1993 • 43 citations

Failure to make normal α ryanodine receptor is an early event associated with the Crooked Neck Dwarf (cn) mutation in chicken

1993 • 42 citations

Calcium, BOBs, QEDs, microdomains and a cellular decision: control of mitotic cell division in sand dollar blastomeres

1996 • 34 citations

Crooked Neck Dwarf (cn) mutant chicken skeletal muscle cells in low density primary cultures fail to express normal α ryanodine receptor and exhibit a partial mutant phenotype

1993 • 33 citations

Calcium Waves and Development

2007 • 31 citations

Posttranslational incorporation of contractile proteins into myofibrils in a cell-free system.

1988 • 29 citations

A Subset of Protein Kinase C Phosphorylation Sites on the Myosin II Regulatory Light Chain Inhibits Phosphorylation by Myosin Light Chain Kinase

1997 • 29 citations

Biological Information Processing: Bits of Progress

1997 • 26 citations

Developmental sequence of expression of voltage-dependent currents in embryonic Xenopus laevis myocytes

1992 • 25 citations

Purification and Characterization of a Kinase-associated, Myofibrillar Smooth Muscle Myosin Light Chain Phosphatase Possessing a Calmodulin-targeting Subunit

1997 • 20 citations

Myosin regulation and calcium transients in fibroblast shape change, attachment, and patching

1989 • 12 citations

Development of myotomal cells in Xenopus laevis larvae.

1988 • 10 citations

Primary structure required for the inhibition of smooth muscle myosin light chain kinase

1992 • 10 citations