Distinct and regulated expression of Notch receptors in hematopoietic lineages and during myeloid differentiation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Notch Signaling

1995 • 1,282 citations

Multilineage gene expression precedes commitment in the hemopoietic system.

1997 • 757 citations

Expression and function of c-kit in hemopoietic progenitor cells.

1991 • 756 citations

Host resistance directed selectively against H-2-deficient lymphoma variants. Analysis of the mechanism.

1985 • 734 citations

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.

1996 • 717 citations

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

1990 • 675 citations

Jagged: A mammalian ligand that activates notch1

1995 • 617 citations

An Activated Form of Notch Influences the Choice between CD4 and CD8 T Cell Lineages

1996 • 488 citations

A Transplantable Mast-Cell Neoplasm in the Mouse

1957 • 438 citations

Murine B Cell Leukemia Line with Inducible Surface Immunoglobulin Expression

1978 • 388 citations

Identification of a Committed Precursor for the Mast Cell Lineage

1996 • 379 citations

Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line.

1987 • 369 citations

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

2000 • 365 citations

Expression Patterns ofJagged, Delta1, Notch1, Notch2,andNotch3Genes Identify Ligand–Receptor Pairs That May Function in Neural Development

1996 • 360 citations

Evolution and role of Pax genes

1993 • 337 citations

Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule

1991 • 331 citations

The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells

1998 • 328 citations

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium

1994 • 318 citations

Development of mast cells from grafted bone marrow cells in irradiated mice

1977 • 300 citations

An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells

1994 • 298 citations

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

1986 • 288 citations

The Human Homolog of Rat Jagged1Expressed by Marrow Stroma Inhibits Differentiation of 32D Cells through Interaction with Notch1

1998 • 282 citations

Notch as a Mediator of Cell Fate Determination in Hematopoiesis: Evidence and Speculation

1999 • 265 citations

Phagocytosis and cytolysis by a macrophage tumour and its cloned cell line

1975 • 259 citations

The function of the neurogenic genes during epithelial development in the Drosophila embryo

1992 • 248 citations

Mouse Jagged1 Physically Interacts with Notch2 and Other Notch Receptors

1999 • 243 citations

Notch1-Induced Delay of Human Hematopoietic Progenitor Cell Differentiation Is Associated With Altered Cell Cycle Kinetics

1999 • 236 citations

Drosophila hedgehog acts as a morphogen in cellular patterning

1994 • 215 citations

Notch1 and Notch2 Inhibit Myeloid Differentiation in Response to Different Cytokines

1998 • 213 citations

Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand–receptor interactions in intrathymic T cell development

1999 • 197 citations

The Participation of Macrophages and Macrophage Cell Lines in the Activation of T Lymphocytes by Mitogens

1978 • 184 citations

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

1995 • 184 citations

Inhibition of granulocytic differentiation by mNotch1

1996 • 180 citations

The Notch 3 intracellular domain represses Notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters

1999 • 177 citations

A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ hematopoietic precursors

1994 • 176 citations

Complementary and combinatorial patterns of Notch gene family expression during early mouse development

1995 • 172 citations

Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1

2000 • 134 citations

Expression of notch receptors, notch ligands, and fringe genes in hematopoiesis

2000 • 108 citations

Physical Interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 Receptors

2000 • 102 citations

Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development.

1995 • 98 citations

The Human NOTCH1, 2, and 3 Genes Are Located at Chromosome Positions 9q34, 1p13-p11, and 19p13.2-p13.1 in Regions of Neoplasia-Associated Translocation

1994 • 92 citations

Interleukin 3-dependent hematopoietic progenitor cell lines.

1983 • 83 citations

Interleukin-4 inhibits the expression of Kit and tryptase during stem cell factor-dependent development of human mast cells from fetal liver cells

1994 • 73 citations

The Notch locus of Drosophila is required in epidermal cells for epidermal development

1990 • 73 citations

Notch-related genes in animal development.

1995 • 59 citations

Mouse Hox genetic functions

1993 • 54 citations

Detection of mouse mast cell-associated protease mRNA. Heparinase treatment greatly improves RT-PCR of tissues containing mast cell heparin.

1995 • 48 citations

The hematopoietic transcription factor PU.1 is downregulated in human multiple myeloma cell lines

1995 • 34 citations

Murine mast cell lines as indicators of early events in mast cell and basophil development

2000 • 33 citations

Immortalization of Mouse Bone Marrow-Derived Mast Cells with Ad12-SV40 Virus

1993 • 31 citations

Isolation of MYADM, a novel hematopoietic-associated marker gene expressed in multipotent progenitor cells and up-regulated during myeloid differentiation

2000 • 29 citations

Stem cell factor, but not flt3 ligand, induces differentiation and activation of human mast cells.

1996 • 28 citations

Characterization of cDNA clones encoding mouse proteinase 3 (myeloblastine) and cathepsin G

1997 • 20 citations

Characterization of a mast cell line that lacks the extracellular domain of membrane c‐kit

1997 • 19 citations

Deleted Work

1955 • 0 citations