Inhibition of granulocytic differentiation by mNotch1

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1991 • 1,693 citations

Differentiation and proliferation of hematopoietic stem cells

1993 • 1,417 citations

Signalling downstream of activated mammalian Notch

1995 • 1,375 citations

Notch Signaling

1995 • 1,282 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.

1996 • 717 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity.

1995 • 594 citations

The suppressor of hairless protein participates in notch receptor signaling

1994 • 547 citations

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

1996 • 497 citations

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

1994 • 483 citations

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

1996 • 481 citations

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H)

1995 • 476 citations

Hematopoietic regulators: redundancy or subtlety?

1993 • 473 citations

Intrinsic activity of the lin-12 and Notch intracellular domains in vivo

1993 • 466 citations

Truncated Mammalian Notch1 Activates CBF1/RBPJk-Repressed Genes by a Mechanism Resembling That of Epstein-Barr Virus EBNA2

1996 • 459 citations

Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells

1992 • 452 citations

The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

1995 • 430 citations

Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor

1993 • 424 citations

Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei.

1993 • 421 citations

Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line.

1987 • 369 citations

Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos

1993 • 366 citations

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands.

1992 • 354 citations

Notch2: a second mammalian Notch gene

1992 • 346 citations

glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins

1989 • 345 citations

A homolog of Drosophila Notch expressed during mammalian development

1991 • 338 citations

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium

1994 • 318 citations

An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye

1993 • 307 citations

Xotch , the Xenopus Homolog of Drosophila Notch

1990 • 303 citations

An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells

1994 • 298 citations

Delta-Notch Signaling and Drosophila Cell Fate Choice

1994 • 268 citations

Inhibition of Myeloid Differentiation by the Helix-Loop-Helix Protein Id

1992 • 267 citations

Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development

1992 • 253 citations

Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells

1992 • 246 citations

Three Genes in the Human MHC Class III Region near the Junction with the Class II: Gene for Receptor of Advanced Glycosylation End Products, PBX2 Homeobox Gene and a Notch Homolog, Human Counterpart of Mouse Mammary Tumor Gene int-3

1994 • 234 citations

Choosing a cell fate: a view from the Notch locus

1991 • 213 citations

Choosing a cell fate: a view from the Notch locus

1991 • 196 citations

A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ hematopoietic precursors

1994 • 176 citations

Hematopoiesis: how does it happen?

1995 • 169 citations

Mouse notch: expression in hair follicles correlates with cell fate determination.

1993 • 156 citations

Notch: Neurogenesis is only part of the picture

1993 • 145 citations

Motch A and Motch B—Two Mouse Notch Homologues Coexpressed in a Wide Variety of Tissues

1993 • 136 citations

T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells.

1996 • 136 citations

Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats

1993 • 107 citations

Developmental Signalling: Vertebrate ligands for Notch

1995 • 107 citations

The phytofluors: a new class of fluorescent protein probes

1997 • 107 citations

The Human NOTCH1, 2, and 3 Genes Are Located at Chromosome Positions 9q34, 1p13-p11, and 19p13.2-p13.1 in Regions of Neoplasia-Associated Translocation

1994 • 92 citations

Role of Notch and achaete-scute complex in the expression of Enhancer of split bHLH proteins

1995 • 61 citations

The role of the Enhancer of split complex during cell fate determination in Drosophila

1993 • 23 citations

Deleted Work

1955 • 0 citations