The Participation of Macrophages and Macrophage Cell Lines in the Activation of T Lymphocytes by Mitogens

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 1,046 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 921 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 742 citations

A Requirement for Two Cell Types for Antibody Formation in vitro

1967 • 612 citations

Reticulum Cell Sarcoma: An Effector Cell in Antibody-Dependent Cell-Mediated Immunity

1975 • 426 citations

Immune responses in vitro. I. Culture conditions for antibody synthesis

1972 • 426 citations

Absolute Macrophage Dependency of T Lymphocyte Activation by Mitogens

1976 • 425 citations

Identification of Macrophage-Like Characteristics in a Cultured Murine Tumor Line

1975 • 374 citations

The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens.

1975 • 364 citations

THE EFFECTS OF MERCAPTOETHANOL AND OF PERITONEAL MACROPHAGES ON THE ANTIBODY-FORMING CAPACITY OF NONADHERENT MOUSE SPLEEN CELLS IN VITRO

1972 • 267 citations

Chemical, Physical, and Biological Properties of a Lipopolysaccharide from Escherichia coli K-235^*

1967 • 258 citations

Characterization of Lymphocyte-Activating Factor (LAF) Produced by the Macrophage Cell Line, P388D1

1978 • 237 citations

The modulation of lymphocyte functions by molecules secreted by macrophages. I. Description and partial biochemical analysis.

1975 • 229 citations

PROMOTION OF REPLICATION IN LYMPHOID CELLS BY SPECIFIC THIOLS AND DISULFIDES IN VITRO

1973 • 225 citations

SYNERGISTIC INTERACTION OF MACROPHAGES AND LYMPHOCYTES IN ANTIGEN-INDUCED TRANSFORMATION OF LYMPHOCYTES

1970 • 189 citations

Antigen-Induced Proliferation of Guinea Pig Lymphocytes in Vitro: Obligatory Role of Macrophages in the Recognition of Antigen by Immune T-Lymphocytes

1973 • 185 citations

Bidirectional Amplification of Macrophage-Lymphocyte Interactions: Enhanced Lymphocyte Activation Factor Production by Activated Adherent Mouse Peritoneal Cells

1977 • 184 citations

Lymphocyte reactivity in vitro

1970 • 182 citations

Characterization of lymphocyte-activating factor (LAF) produced by a macrophage cell line, P388D1. II. Biochemical characterization of LAF induced by activated T cells and LPS.

1978 • 172 citations

Immune responses in vitro

1972 • 168 citations

MACROPHAGE-LYMPHOCYTE INTERACTION

1973 • 163 citations

THE ROLE OF NONLYMPHOID ACCESSORY CELLS IN THE IMMUNE RESPONSE TO DIFFERENT ANTIGENS

1970 • 158 citations

Immune Response Restoration with Macrophage Culture Supernatants

1971 • 155 citations

INFECTION AND TRANSFORMATION OF MOUSE PERITONEAL MACROPHAGES BY SIMIAN VIRUS 40

1971 • 155 citations

CRITICAL ROLE OF DETERMINANT PRESENTATION IN THE INDUCTION OF SPECIFIC RESPONSES IN IMMUNO-COMPETENT LYMPHOCYTES

1973 • 155 citations

Purification and Properties of Human Lymphocyte Activating Factor (LAF)

1977 • 154 citations

Lymphocyte reactivity in vitro

1970 • 142 citations

Enhancement by Reducing Agents of the Transformation of Human and Rabbit Peripheral Lymphocytes

1970 • 141 citations

Potentiation of the T lymphocyte response to mitogens

1974 • 122 citations

The modulation of lymphocyte functions by molecules secreted by macrophages. II. Conditions leading to increased secretion.

1976 • 117 citations

Activation of purified human thymus-derived (T) cells by mitogens. II. Monocyte- macrophage potentiation of mitogen-induced DNA synthesis.

1976 • 112 citations

Antibody-Dependent Cytolysis of Chicken Erythrocytes by an in Vitro-Established Line of Mouse Peritoneal Macrophages

1975 • 111 citations

Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol.

1977 • 110 citations

THE EFFECT OF 2-MERCAPTOETHANOL ON MURINE MIXED LYMPHOCYTE CULTURES

1974 • 107 citations

BINDING OF AGGREGATED γ-GLOBULIN TO ACTIVATED T LYMPHOCYTES IN THE GUINEA PIG

1974 • 96 citations

Macrophage Requirement for the in Vitro Response to TNP Ficoll: A Thymic Independent Antigen

1976 • 92 citations

Enhancement of DNA Synthesis and cAMP Content of Mouse Thymocytes by Mediator(s) Derived from Adherent Cells

1976 • 91 citations

Macrophages in the mixed leukocyte culture reaction (MLC)

1974 • 90 citations

Role of Mercaptoethanol and Endotoxin in Stimulating B Lymphocyte Colony Formation in Vitro

1976 • 86 citations

The Requirement for Macrophage-Lymphocyte Interaction in T Lymphocyte Proliferation Induced by Generation of Aldehydes on Cell Membranes

1975 • 83 citations

Phytohemagglutinin-Induced Proliferation of Guinea Pig Thymus-Derived Lymphocytes

1976 • 80 citations

Secretion of mediators following T lymphocyte-macrophage interaction is regulated by the major histocompatibility complex.

1977 • 79 citations

The role of fetal calf serum in the primary immune response in vitro.

1977 • 67 citations

Association of a Low Molecular Weight Helper Factor(s) with Thymocyte Proliferative Activity

1977 • 65 citations

Activation of Purified Human Thymus-Derived (T) Cells by Mitogens

1976 • 64 citations

Restoration of Antibody-Forming Capacity in Cultures of Nonadherent Spleen Cells by Mercaptoethanol

1972 • 62 citations

The Role of Macrophages in Thymocyte Mitogenesis

1976 • 61 citations

Macrophages are required for the dextran-sulfate induced activation of B lymphocytes.

1977 • 50 citations

In Vitro Induction of Polyclonal Killer T Cells with 2-Mercaptoethanol and the Essential Role of Macrophages in This Process

1977 • 48 citations

Peritoneal exudate lymphocyte. 3. Dissociation of antigen-reactive lymphocytes from antigen-binding cells in a T lymphocyte enriched population in the guinea pig.

1974 • 44 citations

Macrophages Are Required for the Dextran-Sulfate Induced Activation of B Lymphocytes

1977 • 40 citations

The Role of Adherent Cells in the Immune Response

1976 • 39 citations

Increased Cytolytic T Lymphocyte Activity Induced by 2-Mercaptoethanol in Mixed Leukocyte Cultures: Kinetics and Possible Mechanisms of Action

1976 • 30 citations

FUNCTION OF GLASS-ADHERENT CELLS IN HUMAN MIXED LYMPHOCYTE CULTURES

1970 • 28 citations

Characterization of Guinea Pig Mitogenic Factor

1975 • 27 citations

The Molecular Dimensions of Mitogenic Factor from Guinea Pig Lymph Node Cells

1975 • 26 citations

A Permanent Line of Macrophages with Normal Activity in a Primary Antibody ResponseIn Vitro

1973 • 24 citations

Chemical Modulation of Cell Surfaces by Sulfhydryl Compounds: Effect on C3b Receptors

1974 • 22 citations

Augmentation of Proliferation and in Vitro Production of Cytotoxic Cells by 2-Me in the Rat

1975 • 20 citations

Thymocytes, macrophages, and erythrocytes

1974 • 17 citations

Characterization of lymphocyte activating factor from mouse tumor cell lines and human leukocytes

1976 • 8 citations