Type-I Interferon Receptor Deficiency Reduces Lupus-like Disease in NZB Mice

Functional Role of Type I and Type II Interferons in Antiviral Defense

1994 • 2,437 citations

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.

1978 • 1,619 citations

Natural adjuvants: Endogenous activators of dendritic cells

1999 • 1,611 citations

Murine Models of Systemic Lupus Erythematosus

1985 • 1,572 citations

IRF Family of Transcription Factors as Regulators of Host Defense

2001 • 1,566 citations

Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

1998 • 1,262 citations

Induction of Dendritic Cell Differentiation by IFN-α in Systemic Lupus Erythematosus

2001 • 1,245 citations

Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo

1996 • 1,077 citations

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

2001 • 1,017 citations

Type I Interferons Potently Enhance Humoral Immunity and Can Promote Isotype Switching by Stimulating Dendritic Cells In Vivo

2001 • 942 citations

Type I Interferons Keep Activated T Cells Alive

1999 • 769 citations

The Peptide Ligands Mediating Positive Selection in the Thymus Control T Cell Survival and Homeostatic Proliferation in the Periphery

1999 • 742 citations

Cd11c+B220+Gr-1+ Cells in Mouse Lymph Nodes and Spleen Display Characteristics of Plasmacytoid Dendritic Cells

2001 • 717 citations

CYCLINS AND CELL CYCLE CHECKPOINTS

1999 • 706 citations

Interferons α and β as Immune Regulators—A New Look

2001 • 671 citations

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

1993 • 638 citations

Maintaining the norm: T-cell homeostasis

2002 • 608 citations

Delineating the Genetic Basis of Systemic Lupus Erythematosus

2001 • 562 citations

A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells

1983 • 561 citations

CXCL13 Is Required for B1 Cell Homing, Natural Antibody Production, and Body Cavity Immunity

2002 • 521 citations

A weak signal for strong responses: interferon-alpha/beta revisited

2001 • 471 citations

Systemic Lupus Erythematosus: Presence in Human Serum of an Unusual Acid-Labile Leukocyte Interferon

1982 • 460 citations

Failure to Suppress the Expansion of the Activated Cd4 T Cell Population in Interferon γ–Deficient Mice Leads to Exacerbation of Experimental Autoimmune Encephalomyelitis

2000 • 424 citations

Evidence for an Interferon-Inducible Gene, Ifi202, in the Susceptibility to Systemic Lupus

2001 • 371 citations

Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice.

1998 • 354 citations

Cross Talk Between Interferon-γ and -α/β Signaling Components in Caveolar Membrane Domains

2000 • 316 citations

GENETIC SUSCEPTIBILITY TO SYSTEMIC LUPUS ERYTHEMATOSUS

1998 • 313 citations

Roles of interferon-gamma and interleukin-4 in murine lupus.

1997 • 301 citations

Activation of Natural Killer T Cells Potentiates or Prevents Experimental Autoimmune Encephalomyelitis

2001 • 294 citations

Induction of Type I Diabetes by Interferon-α in Transgenic Mice

1993 • 289 citations

Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice

1992 • 281 citations

Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy

2000 • 256 citations

IFN‐α/β enhances BCR‐dependent B cell responses

2002 • 250 citations

IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice.

1998 • 247 citations

CD8+ T Cell–Mediated Skin Disease in Mice Lacking IRF-2, the Transcriptional Attenuator of Interferon-α/β Signaling

2000 • 239 citations

Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen.

1993 • 234 citations

The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity.

2001 • 212 citations

IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice.

1998 • 211 citations

IFN-γ Receptor Signaling Is Essential for the Initiation, Acceleration, and Destruction of Autoimmune Kidney Disease in MRL-FaslprMice

1998 • 202 citations

An etiopathogenic role for the type I IFN system in SLE

2001 • 193 citations

Experimental therapy of systemic lupus erythematosus: the treatment of NZB/W mice with mouse soluble interferon‐γ receptor inhibits the onset of glomerulonephritis

1995 • 188 citations

Interferon γ (IFN-γ) Is Necessary for the Genesis of Acetylcholine Receptor–induced Clinical Experimental Autoimmune Myasthenia gravis in Mice

1997 • 183 citations

IFN-γ Receptor Deletion Prevents Autoantibody Production and Glomerulonephritis in Lupus-Prone (NZB × NZW)F1 Mice

1998 • 173 citations

Impairment of T and B Cell Development by Treatment with a Type I Interferon

1998 • 165 citations

Treatment of murine lupus with cDNA encoding IFN-γR/Fc

2000 • 162 citations

IFNα/β promotes cell survival by activating NF-κB

2000 • 155 citations

Prevention of autoimmune symptoms in autoimmune-prone mice by elimination of B-1 cells

1995 • 154 citations

The pathogenesis of autoimmunity in New Zealand

2000 • 137 citations

Reduced Incidence and Severity of Antigen-induced Autoimmune Diseases in Mice Lacking Interferon Regulatory Factor-1

1997 • 131 citations

The Interferon Regulatory Transcription Factor IRF-1 Controls Positive and Negative Selection of CD8+ Thymocytes

1997 • 112 citations

Mice with IFN-gamma receptor deficiency are less susceptible to experimental autoimmune myasthenia gravis.

1999 • 111 citations

Transfer of Small Resting B Cells into Immunodeficient Hosts Results in the Selection of a Self-renewing Activated B Cell Population

1999 • 108 citations

Mice with IFN-γ Receptor Deficiency Are Less Susceptible to Experimental Autoimmune Myasthenia Gravis

1999 • 98 citations

Genetics of Systemic Autoimmunity in Mouse Models of Lupus

2000 • 96 citations

Administration of interleukin ‐5 or ‐10 activates peritoneal B‐1 cells and induces autoimmune hemolytic anemia in anti‐erythrocyte autoantibody‐transgenic mice

1995 • 83 citations

Interferon‐β therapy for multiple sclerosis induces reciprocal changes in interleukin‐12 and interleukin‐10 production

2001 • 81 citations

Inhibition of B Cell Receptor-Mediated Apoptosis by IFN

1999 • 75 citations

Genetic dissection of B cell traits in New Zealand black mice. The expanded population of B cells expressing up-regulated costimulatory molecules shows linkage toNba2

2000 • 74 citations

Anti-interferon globulin inhibits the development of glomerulonephritis in mice infected at birth with lymphocytic choriomeningitis virus.

1978 • 74 citations

Immunotherapy of multiple sclerosis: Where are we? Where should we go?

2001 • 68 citations

Requirement of the IFN‐α/β‐induced CXCR3 chemokine signalling for CD8⁺ T cell activation

2002 • 64 citations

Complete Suppression of Insulitis and Diabetes in NOD mice Lacking Interferon Regulatory Factor-1

2001 • 61 citations

The pathogenesis of autoimmunity in New Zealand mice. II. Acceleration of glomerulonephritis by polyinosinic-polycytidylic acid.

1970 • 57 citations

Interferon-inducible p202 in the susceptibility to systemic lupus

2002 • 56 citations

Interleukin-10 modulates the sensitivity of peritoneal B lymphocytes to chemokines with opposite effects on stromal cell–derived factor-1 and B-lymphocyte chemoattractant

2002 • 54 citations

Resting B cells from New Zealand Black mice demonstrate a defect in apoptosis induction following surface IgM ligation.

1996 • 51 citations

G1 arrest and high expression of cyclin kinase and apoptosis inhibitors in accumulated activated/memory phenotype CD4⁺ cells of older lupus mice

1997 • 44 citations

Activation and Differentiation of Autoreactive B-1 Cells by Interleukin 10 Induce Autoimmune Hemolytic Anemia in Fas-deficient Antierythrocyte Immunoglobulin Transgenic Mice

2002 • 43 citations

IFN-alpha treatment suppresses the development of experimental autoimmune myasthenia gravis.

1995 • 39 citations

Interferon-inducible p202 in the susceptibility to systemic lupus

2002 • 38 citations

IFNα/βはNF‐κBを活性化して細胞生存を促進する

2000 • 34 citations

Interferon-β increases the stimulatory capacity of monocyte-derived dendritic cells to induce IL-13, IL-5 and IL-10 in autologous T-cells

2002 • 30 citations

IFN-alpha therapy is effective in suppressing the clinical experimental myasthenia gravis.

1996 • 28 citations

Novel ELISA and ELISA-spot assays used to quantitate B cells and serum antibodies specific for T cell and bromelated mouse red blood cell autoantigens

1987 • 27 citations

Interleukin-12 and -10 and gamma interferon regulate polyclonal and ligand-specific expansion of murine B-1 cells

1996 • 23 citations

Autoantibody Production and Cytokine Profiles of MHC Class I (β 2 -Microglobulin) Gene Deleted New Zealand Black (NZB) Mice

1997 • 18 citations

In Vitro and In Vivo Expression Analysis of the Interferon-Inducible 203 Gene

1999 • 17 citations