The pathogenesis of autoimmunity in New Zealand

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

ANTIBODIES TO HUMAN T-LYMPHOTROPIC VIRUS TYPE-I IN PATIENTS WITH TROPICAL SPASTIC PARAPARESIS

1985 • 2,840 citations

The clonal selection theory of acquired immunity

1959 • 2,008 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.

1978 • 1,619 citations

Murine Models of Systemic Lupus Erythematosus

1985 • 1,572 citations

Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.

1975 • 1,105 citations

The somatic generation of immune recognition

1971 • 974 citations

MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment

1999 • 973 citations

The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice.

1983 • 810 citations

The Immunology and Pathology of NZB Mice

1968 • 664 citations

Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies.

1984 • 652 citations

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus.

1993 • 637 citations

PATHOGENESIS OF THE GLOMERULONEPHRITIS OF NZB/W MICE

1968 • 622 citations

Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis

1988 • 599 citations

Progenitors for Ly-1 B cells are distinct from progenitors for other B cells.

1985 • 599 citations

T Cell Control of Antibody Production

1974 • 582 citations

Anionic sites in the glomerular basement membrane. In vivo and in vitro localization to the laminae rarae by cationic probes.

1979 • 554 citations

COOPERATING AND CONTROLLING FUNCTIONS OF THYMUS-DERIVED LYMPHOCYTES IN RELATION TO AUTOIMMUNITY

1971 • 534 citations

Human Lymphocytes Making Rheumatoid Factor and Antibody to ssDNA Belong to Leu-1⁺B-Cell Subset

1987 • 490 citations

Polygenic control of susceptibility to murine systemic lupus erythematosus

1994 • 484 citations

The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor

1989 • 476 citations

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

1985 • 466 citations

IgG2a restriction of murine antibodies elicited by viral infections.

1987 • 429 citations

Differential function of major histocompatibility complex antigens in T-lymphocyte activation

1976 • 419 citations

In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon.

1987 • 396 citations

Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis.

1995 • 371 citations

Lupus susceptibility loci in New Zealand mice.

1994 • 359 citations

GENETIC CONTROL OF THE ANTIBODY RESPONSE TO TYPE III PNEUMOCOCCAL POLYSACCHARIDE IN MICE

1972 • 349 citations

Nutrition and immunity.

1985 • 333 citations

Renal Disease associated with Positive Lupus Erythematosus Tests in a Crossbred Strain of Mice

1963 • 330 citations

Peritoneal Ly‐1 B cells: Genetic control, autoantibody production, increased lambda light chain expression

1986 • 306 citations

Increased Spontaneous Polyclonal Activation of B Lymphocytes in Mice with Spontaneous Autoimmune Disease

1978 • 305 citations

Androgenic Hormones Modulate Autoantibody Responses and Improve Survival in Murine Lupus

1977 • 303 citations

Normal, Autoimmune, and Malignant CD5+ B Cells: The LY-1 B Lineage?

1988 • 302 citations

Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice.

1978 • 296 citations

Development and Function of Subpopulations of Thymocytes and T Lymphocytes

2015 • 296 citations

Production of Immunoglobulin Isotypes by Ly-1 ⁺ B Cells in Viable Motheaten and Normal Mice

1986 • 290 citations

Nucleic Acids in Immunology

1968 • 279 citations

Levamisole in the modulation of the immune response: the current experimental and clinical state.

1977 • 277 citations

THE VIRAL ENVELOPE GLYCOPROTEIN OF MURINE LEUKEMIA VIRUS AND THE PATHOGENESIS OF IMMUNE COMPLEX GLOMERULONEPHRITIS OF NEW ZEALAND MICE

1974 • 277 citations

Functional dissection of systemic lupus erythematosus using congenic mouse strains.

1997 • 268 citations

A systemic lupus erythematosus (SLE)‐like disease in mice induced by abnormal T‐B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

1982 • 267 citations

Polymorphism of the major envelope glycoprotein (gp70) of murine C-type viruses: virion associated and differentiation antigens encoded by a multi-gene family

1977 • 260 citations

Tumor necrosis factor and IL-1 in New Zealand Black/White mice. Enhanced gene expression and acceleration of renal injury.

1989 • 255 citations

Leu-1+ (CD5+) B cells. A major lymphoid subpopulation in human fetal spleen: phenotypic and functional studies.

1986 • 245 citations

Failure of autologous mixed lymphocyte reactions between T and non-T cells in patients with systemic lupus erythematosus.

1978 • 236 citations

Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis.

1987 • 236 citations

Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity.

1997 • 234 citations

Loss of suppressor T cells in adult NZB/NZW mice.

1976 • 229 citations

B.C.G. VACCINATION AND LEUKÆMIA MORTALITY

1970 • 226 citations

Developmental Biology of T Cell Receptors

1989 • 223 citations

Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus.

1979 • 223 citations

Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.

1998 • 221 citations

Anti-CD40 ligand antibody treatment prevents the development of lupus-like nephritis in a subset of New Zealand black x New Zealand white mice. Response correlates with the absence of an anti-antibody response.

1996 • 220 citations

X-linked B-lymphocyte immune defect in CBA/HN mice. I. Studies of the function and composition of spleen cells.

1975 • 216 citations

Normal mouse peritoneum contains a large population of Ly-1+ (CD5) B cells that recognize phosphatidyl choline. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes.

1988 • 214 citations

Apoptosis signaling in lymphocytes

1999 • 212 citations

Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4.

1987 • 211 citations

Treatment of (NZB x NZW)F1 disease with anti-I-A monoclonal antibodies.

1983 • 208 citations

Endogenous oncornaviral gene expression in adult and fetal mice: quantitative, histologic, and physiologic studies of the major viral glycorprotein, gp70.

1976 • 207 citations

Decline in Suppressor T Cell Function with Age in Female NZB Mice

1974 • 206 citations

The basis of autoimmunity: part II genetic predisposition

1995 • 205 citations

Natural Thymocytotoxic Autoantibody and Reactive Antigen in New Zealand Black and Other Mice

1971 • 205 citations

Expression of Lyt-1 by a subset of B lymphocytes.

1982 • 204 citations

THE INTERACTION BETWEEN HUMAN MONOCYTES AND RED CELLS

1970 • 202 citations

Polymorphism of murine Fas ligand that affects the biological activity

1997 • 201 citations

Epistatic Modifiers of Autoimmunity in a Murine Model of Lupus Nephritis

1999 • 200 citations

The Natural History of Autoimmune Disease in NZB Mice

1963 • 200 citations

Features of systemic lupus erythematosus in mice injected with bacterial lipopolysaccharides: identificantion of circulating DNA and renal localization of DNA-anti-DNA complexes.

1977 • 194 citations

A single VH gene is utilized predominantly in anti-BrMRBC hybridomas derived from purified Ly-1 B cells. Definition of the VH11 family.

1989 • 192 citations

Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes.

1988 • 189 citations

Selenium and immune responses

1987 • 187 citations

THE INFLUENCE OF THE GONADS AND ADRENAL GLANDS ON THE IMMUNE RESPONSE TO SKIN GRAFTS

1969 • 183 citations

Demonstration of Activation of B Lymphocytes in New Zealand Black Mice at Birth by an Immunoradiometric Assay for Murine IgM

1977 • 183 citations

FURTHER IMPLICATION OF MURINE LEUKEMIA-LIKE VIRUS IN THE DISORDERS OF NZB MICE

1969 • 182 citations

IMMUNOPATHOLOGY OF NZB/BL MICE

1966 • 182 citations

RELEASE OF DNA IN CIRCULATING BLOOD AND INDUCTION OF ANTI-DNA ANTIBODIES AFTER INJECTION OF BACTERIAL LIPOPOLYSACCHARIDES

1974 • 182 citations

DIABETOGENIC DRUGS

1976 • 180 citations

Subpopulations of Thymus Cells and Thymus-Derived Lymphocytes

1971 • 176 citations

Genetic Dissection of Sle Pathogenesis:Sle3on Murine Chromosome 7 Impacts T Cell Activation, Differentiation, and Cell Death

1999 • 176 citations

THE PATHOGENESIS OF AUTOIMMUNITY IN NEW ZEALAND MICE, I. INDUCTION OF ANTINUCLEIC ACID ANTIBODIES BY POLYINOSINIC·POLYCYTIDYLIC ACID

1969 • 173 citations

Charge of circulating immune complexes as a factor in glomerular basement membrane localization in mice.

1981 • 173 citations

Chronic therapy with recombinant tumor necrosis factor-α in autoimmune NZB/NZW F1 mice

1989 • 169 citations

Development and Function of Subpopulations of Thymocytes and T Lymphocytes (Part 1 of 2)

1975 • 168 citations

Influence of dietary restriction on immunologic function and renal disease in (NZB × NZW) F ₁ mice

1978 • 167 citations

Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes.

1979 • 167 citations

A Role for Fas in Negative Selection of Thymocytes In Vivo

1998 • 167 citations

Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice.

1980 • 166 citations

Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies

1999 • 166 citations

RELATIVE INABILITY TO INDUCE TOLERANCE IN ADULT NZB AND NZB/NZW F1 MICE

1969 • 164 citations

WILD-TYPE GROSS LEUKEMIA VIRUS AND THE PATHOGENESIS OF THE GLOMERULONEPHRITIS OF NEW ZEALAND MICE

1971 • 162 citations

Feedback regulation of murine Ly‐1 B cell development

1989 • 161 citations

Spontaneous Auto‐Immune Disease in NZB/BL Mice

1963 • 159 citations

Molecular cloning of Ly-1, a membrane glycoprotein of mouse T lymphocytes and a subset of B cells: molecular homology to its human counterpart Leu-1/T1 (CD5).

1987 • 155 citations

Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice.

1997 • 153 citations

Strain differences in the immune response of mice. I. The neonatal response to sheep red cells.

1968 • 150 citations

B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes.

1995 • 149 citations

THE EFFECT OF INDUCED CHRONIC VIRAL INFECTIONS ON THE IMMUNOLOGIC DISEASES OF NEW ZEALAND MICE

1970 • 148 citations

Simultaneous cell cycle analysis and two-color surface immunofluorescence using 7-amino-actinomycin D and single laser excitation: applications to study of cell activation and the cell cycle of murine Ly-1 B cells.

1986 • 147 citations

Demonstration of Biological Activity of a Murine Leukemia Virus of New Zealand Black Mice

1970 • 146 citations

Changes in immunoglobulin class and subclass of anti-DNA antibodies with increasing age in N/ZBW F1 hybrid mice.

1976 • 146 citations

Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner.

1995 • 146 citations

The contribution of NZW genes to lupus-like disease in (NZB x NZW)F1 mice.

1987 • 146 citations

A laboratory model for Sjögren's syndrome.

1968 • 145 citations

Mechanisms of T and B cell collaboration in the in vitro production of anti-DNA antibodies in the NZB/NZW F1 murine SLE model.

1987 • 145 citations

Immunological regulation of spontaneous antibodies to DNA and RNA. II. Sequential switch from IgM to IgG in NZB/NZW F1 mice.

1977 • 145 citations

Immunologic and viral factors in the pathogenesis of systemic lupus erythematosus

1970 • 143 citations

Restricted Ig variable region gene expression among Ly-1+ B cell lymphomas.

1988 • 141 citations

Studies on thymus products. IV. Absence of serum 'thymic activity' in adult NZB and (NZB x NZW) F1 mice.

1973 • 134 citations

Prostaglandin e₁ treatment of NZB/NZW F₁ hybrid MICE

1977 • 132 citations

Effect of genetic background on the contribution of New Zealand Black loci to autoimmune lupus nephritis

1996 • 130 citations

Enhancement of the antibody response to type 3 pneumococcal polysaccharide in mice treated with antilymphocyte serum.

1970 • 130 citations

B-1 Cells: unique origins and functions

1996 • 129 citations

Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice

1998 • 127 citations

Unusual phenotype of B cells in the thymus of normal mice.

1988 • 127 citations

The Immunological Significance of the Thymus

1963 • 126 citations

Syngeneic Mixed Lymphocyte Reaction in Mice: Strain Distribution, Kinetics, Participating Cells, and Absence in NZB Mice

1978 • 126 citations

Characterization of self-reactive B cells by polyclonal B-cell activators.

1977 • 125 citations

The Genetics of the Immune Response to a Synthetic Double-Stranded RNA in a Mutant CBA Mouse Strain

1973 • 123 citations

Estrogen induces normal murine CD5+ B cells to produce autoantibodies.

1989 • 122 citations

Induction of Red Cell Autoantibodies in Normal Mice

1973 • 122 citations

Synthesis of IgM by Cells of NZB and SWR Mice and Their Crosses

1979 • 122 citations

Genetic linkage of IgG autoantibody production in relation to lupus nephritis in New Zealand hybrid mice.

1996 • 122 citations

Pathological changes of thymic epithelial cells and autoimmune disease in NZB, NZW and (NZB x NZW)F1 mice.

1967 • 121 citations

Selective Loss of Suppressor Cell Function in New Zealand Mice Induced by NTA

1977 • 121 citations

AUTOIMMUNE DISEASE IN NZB/BL MICE

1965 • 118 citations

SYNERGY AMONG LYMPHOID CELLS MEDIATING THE GRAFT-VERSUS-HOST RESPONSE

1970 • 118 citations

Loss with age in NZB-W mice of thymic suppressor cells in the graft-vs-host reaction.

1974 • 118 citations

Development of autoimmune disease in SCID mice populated with long-term "in vitro" proliferating (NZB x NZW)F1 pre-B cells.

1992 • 116 citations

IMMUNOPATHOLOGY OF NEW ZEALAND BLACK (NZB) MICE

1965 • 116 citations

Genetic studies in NZB mice. V. Recombinant inbred lines demonstrate that separate genes control autoimmune phenotype.

1981 • 116 citations

Permanent alteration of the murine Ly‐1 B repertoire due to selective depletion of Ly‐1 B cells in neonatal animals

1989 • 116 citations

CYCLOPHOSPHAMIDE TREATMENT OF RENAL DISEASE IN (NZB × NZW) F1 HYBRID MICE

1968 • 115 citations

X-linked B-lymphocyte defect in CBA/N mice. III. Abnormal development of B-lymphocyte populations defined by their density of surface immunoglobulin.

1976 • 115 citations

Intrinsic B cell defects in NZB and NZW mice contribute to systemic lupus erythematosus in (NZB x NZW)F1 mice.

1996 • 113 citations

Lupus: Key Pathogenic Mechanisms and Contributing Factors

1995 • 112 citations

Autoimmunity and Neoplasia: The Possible Role of C-type Viruses

1974 • 110 citations

Pathogenesis of immune complex glomerulonephritis of New Zealand mice.

1971 • 109 citations

B cell dependence on and response to accessory signals in murine lupus strains.

1983 • 108 citations

Genetic Dissection of SLE Pathogenesis: Adoptive Transfer ofSle1Mediates the Loss of Tolerance by Bone Marrow-Derived B Cells

1999 • 108 citations

Differential Cytotoxic Effect of Natural Thymocytotoxic Autoantibody of NZB Mice on Functional Subsets of T Cells

1978 • 107 citations

Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. III. Dual gene control of the T-cell-mediated suppression of the antibody response.

1976 • 107 citations

Functional Analysis of B Cell Heterogeneity

1975 • 106 citations

The role of NZB/NZW F₁ thymus in experimental tolerance and auto‐immunity

1970 • 106 citations

IMMUNOPATHOLOGY OF NZB/BL MICE

1967 • 104 citations

Suppression of NZB/NZW murine nephritis by administration of a syngeneic monoclonal antibody to DNA. Possible role of anti-idiotypic antibodies.

1983 • 104 citations

Immunopathology and Neoplasms in New Zealand Black (NZB) and SJL/J Mice

2015 • 103 citations

AUTOIMMUNE REACTIONS AND VIRUS-LIKE PARTICLES IN GERM-FREE NZB MICE

1967 • 102 citations

Depletion of the predominant B-cell population in immunoglobulin µ heavy-chain transgenic mice

1987 • 102 citations

Requirement of H‐2 heterozygosity for autoimmunity in (NZB × NZW)F₁ hybrid mice

1986 • 101 citations

Genetic studies of autoimmunity in New Zealand mice. IV. Contribution of NZB and NZW genes to the spontaneous occurrence of retroviral gp70 immune complexes in (NZB X NZW)F1 hybrid and the correlation to renal disease.

1983 • 100 citations

NZB/NZW mice as a model of systemic lupus erythematosus.

1966 • 100 citations

Specific inhibition of antibody production. I. Protein-over loading paralysis.

1962 • 99 citations

Response of NZB and NZB/NZW Spleen Cells to Mitogenic Agents

1970 • 98 citations

The Significance of Cutaneous Immunoglobulin Deposits In Lupus Erythematosus And Nzb/Nzw F1 Hybrid Mice

1975 • 96 citations

The BM12 mutation and autoantibodies to dsDNA in NZB.H-2bm12 mice.

1990 • 96 citations

Host Immunoglobulin G and Complement Deposits in the Choroid Plexus during Spontaneous Immune Complex Disease

1973 • 95 citations

Effect of Estrogen and Cortisone on Immune Hemoantibodies in Mice of Inbred Strains

1955 • 95 citations

Genetic studies in NZB mice. I. Spontaneous autoantibody production.

1978 • 94 citations

Lymphocyte Subpopulations in NZB Mice: Deficit of Thymus-Dependent Lymphocytes

1972 • 93 citations

THE NATURAL HISTORY OF THE NZB/NZW F1 HYBRID MOUSE: A LABORATORY MODEL OF SYSTEMIC LUPUS ERYTHEMATOSUS

1965 • 93 citations

Surface immunoglobulins of lipopolysaccharide‐stimulated spleen cells The behaviour of IgM, IgD and IgG

1977 • 92 citations

Reversal of nzb/nzw disease with total lymphoid irradiation.

1979 • 91 citations

The genetic contribution of the NZB mouse to the renal disease of the NZB x NZW hybrid.

1977 • 91 citations

Abnormal Polyclonal B Cell Activation in NZB/NZW F1 Mice

1977 • 90 citations

Mutational analysis of TNF-alpha gene reveals a regulatory role for the 3'-untranslated region in the genetic predisposition to lupus-like autoimmune disease.

1996 • 90 citations

A comparative immunologic analysis of several murine strains with autoimmune manifestations

1980 • 90 citations

V Genes Encoding Autoantibodies: Molecular and Phenotypic Characteristics

1988 • 89 citations

Tumor necrosis factor alpha in murine systemic lupus erythematosus disease models: Implications for genetic predisposition and immune regulation

1991 • 89 citations

Double-Helical Polynucleotides: Immunochemical Recognition of Differing Conformations

1970 • 89 citations

Defective colony formation by B lymphocytes from CBA/N and C3H/HeJ mice.

1977 • 89 citations

Antinuclear Factor in Mice

1964 • 88 citations

Supressor Cells in the Graft vs Host Reaction

1973 • 88 citations

Autoimmune phenomena and renal disease in mice. Role of thymectomy, aging, and involution of immunologic capacity.

1970 • 87 citations

THE IMMUNOLOGICAL SIGNIFICANCE OF THE THYMUS

1962 • 86 citations

Natural cytotoxic autoantibody against thymocytes in NZB mice.

1972 • 86 citations

Differential expression of a zinc finger-encoding gene in response to positive versus negative signaling through receptor immunoglobulin in murine B lymphocytes.

1989 • 86 citations

AUTOIMMUNE DISEASE IN MICE^*

1965 • 86 citations

Linkage of a major quantitative trait locus toYaa gene-induced lupus-like nephritis in (NZW × C57BL/6)F1 mice

1998 • 85 citations

INDUCTION OF IMMUNOLOGIC TOLERANCE IN OLDER NEW ZEALAND MICE REPOPULATED WITH YOUNG SPLEEN, BONE MARROW, OR THYMUS

1970 • 84 citations

Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice I. Xenotropic virus.

1978 • 84 citations

Thymic changes in the mouse strain NZB in relation to the auto‐immune state

1964 • 83 citations

The genetic origin of autoantibodies

1987 • 83 citations

Is anticardiolipin activity a cross‐reaction of anti‐DNA or a separate entity?

1987 • 83 citations

Therapeutic studies in NZB/W mice. II. Relative efficacy of azathioprine, cyclophosphamide and methylprednisolone

1972 • 83 citations

The appearance of immunological competence at an early age in New Zealand black mice.

1968 • 82 citations

Evidence for A B Lymphocyte Defect Underlying the Anti-X Anti-Erythrocyte Autoantibody Response of NZB Mice

1977 • 81 citations

Normal mice express idiotypes related to autoantibody idiotypes of lupus mice

1983 • 81 citations

Deficient Immunologic Functions of NZB Mice

1968 • 81 citations

Mast cells in the thymus of NZB mice

1965 • 79 citations

Murine xenotropic type C viruses I. Distribution and further characterization of the virus in NZB mice

1975 • 78 citations

CD4+ T cell lines with selective patterns of autoreactivity as well as CD4- CD8- T helper cell lines augment the production of idiotypes shared by pathogenic anti-DNA autoantibodies in the NZB x SWR model of lupus nephritis.

1988 • 78 citations

Backcross analysis of genes linked to autoantibody production in New Zealand White mice.

1996 • 77 citations

Genetic Investigations of Autoimmune Disease in Mice

1965 • 77 citations

The natural history and immunopathology of outbred athymic (nude) mice

1975 • 75 citations

Study of Autoimmune Disease in New Zealand Mice

1968 • 75 citations

Genetics of expression of xenotropic virus and autoimmunity in NZB mice

1976 • 75 citations

Spleen cells from animals tolerant to a thymus-dependent antigen can be activated by lipopolysaccharide to synthesize antibodies against the tolerogen.

1976 • 74 citations

The role of low affinity antibody in immune complex disease. The quantity of anti-DNA antibodies in NZB/W F1 hybrid mice.

1975 • 73 citations

B lymphocyte reconstitution after human bone marrow transplantation. Leu-1 antigen defines a distinct population of B lymphocytes.

1987 • 73 citations

CBA/N X-linked B-cell defect prevents NZB B-cell hyperactivity in F1 mice.

1979 • 72 citations

Thymus-dependent and thymus-independent developmental pathways for peripheral T cell receptor-gamma delta-bearing lymphocytes.

1988 • 72 citations

Genetic studies of autoimmunity in New Zealand mice. III. Associations among anti-DNA antibodies, NTA, and renal disease in (NZB x NZW)F1 x NZW backcross mice.

1981 • 71 citations

Immunologic abnormality in NZB/NZW F1 mice. Thymus-independent occurrence of B cell abnormality and requirement for T cells in the development of autoimmune disease, as evidenced by an analysis of the athymic nude individuals.

1988 • 71 citations

IMMUNOPATHOGENICITY AND ONCOGENICITY OF MURINE LEUKEMIA VIRUSES

1974 • 70 citations

Expression of autoimmunity by marrow

1978 • 70 citations

Analysis of recombinant inbred lines derived from "autoimmune" (NZB) and "high leukemia" (C58) strains: independent multigenic systems control B cell hyperactivity, retrovirus expression, and autoimmunity.

1982 • 69 citations

The influence of sex upon the antibody response to an incompatible tumour.

1965 • 69 citations

Suppression of autoimmune hemolytic anemia in New Zealand (NZB) mice by syngeneic young thymocytes

1975 • 69 citations

Clonal analysis of the anti-DNA repertoire of murine B lymphocytes.

1987 • 68 citations

TRANSMISSION BY SPLENIC CELLS OF AN AUTOIMMUNE DISEASE OCCURING SPONTANEOUSLY IN MICE

1961 • 68 citations

The pathogenesis of autoimmunity in New Zealand mice. 3. Factors influencing the formation of anti-nucleic acid antibodies.

1971 • 68 citations

Idiotype restriction in murine lupus; high frequency of three public idiotypes on serum IgG in nephritic NZB/NZW F1 mice.

1987 • 68 citations

The transcapsular route: a new way for (self-) antigens to by-pass the blood-thymus barrier?

1988 • 67 citations

Effects of major histocompatibility complex on autoimmune disease of H-2-congenic New Zealand Mice

1990 • 67 citations

The NZB X SWR model of lupus nephritis. I. Cross-reactive idiotypes of monoclonal anti-DNA antibodies in relation to antigenic specificity, charge, and allotype. Identification of interconnected idiotype families inherited from the normal SWR and the autoimmune NZB parents.

1987 • 67 citations

Are B lymphocytes the principal antigen-presenting cells in vivo?

1988 • 67 citations

Mechanism of allograft rejection in New Zealand mice. I. Cell synergy and its age-dependent loss.

1973 • 67 citations

Autoimmunization in murine graft-vs-host disease. I. Selective production of antibodies to histones and DNA.

1985 • 67 citations

CD5+ B cells in autoimmune disease and lymphoid malignancy

1991 • 67 citations

TCR gamma delta cells--minor redundant T cell subset or specialized immune system component?

1989 • 66 citations

Enhancing effect of H-2-linked NZW gene(s) on the autoimmune traits of (NZB X NZW)F1 mice.

1983 • 66 citations

Reaction patterns of monoclonal antibodies to DNA.

1988 • 65 citations

POSTTHYMECTOMY WASTING ASSOCIATED WITH AUTOIMMUNE PHENOMENA

1967 • 65 citations

COMPARISON OF THE IMMUNE RESPONSIVENESS OF NZB AND NZB x NZW F1 HYBRID MICE WITH THAT OF OTHER STRAINS OF MICE

1969 • 65 citations

Thymosin Corrects the Abnormal DNA Synthetic Response of NZB Mouse Thymocytes

1974 • 65 citations

Age-Dependent Loss in New Zealand Mice of Morphological and Functional Characteristics of Thymic Epithelial Cells

1978 • 64 citations

In Vitro Studies of the Genetically Determined Unresponsiveness to Thymus-Independent Antigens in CBA/N Mice

1976 • 64 citations

Genesis of antinuclear antibody in NZB-W mice: role of genetic factors and of viral infections.

1970 • 63 citations

Studies of reticuloendothelial function in the mouse with model immune complexes. II. Serum clearance, tissue uptake, and reticuloendothelial saturation in NZB/W mice.

1979 • 63 citations

Immune Response to a Soluble Protein Antigen in NZB Mice

1968 • 63 citations

Genetic Determinants of Autoimmune Disease and Coronary Vasculitis in the MRL-lpr/lprMouse Model of Systemic Lupus Erythematosus

1998 • 62 citations

Oncornavirus envelope glycoprotein in serum of mice

1976 • 62 citations

Age-decrease of cells sensitive to an autoantibody-specific for thymocytes and thymus-dependent lymphocytes in NZB mice.

1972 • 61 citations

Peritoneal B cells respond to phorbol esters in the absence of co-mitogen.

1988 • 61 citations

Progressive loss in vitro of cellular immunity with ageing in strains of mice susceptible to autoimmune disease.

1971 • 60 citations

EFFECT OF THYMOSIN ON THYMOCYTE PROLIFERATION AND AUTOIMMUNITY IN NZB MICE

1975 • 60 citations

Karyotypic, Virologic, and Immunologic Analyses of Two Continuous Lymphocyte Lines Established from New Zealand Black Mice: Possible Relationship of Chromosomal Mosaicism to Autoimmunity

1972 • 60 citations

Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice. II. The viral envelope glycoprotein gp70.

1978 • 60 citations

Co‐expression of Mac‐1 and p150,95 on CD5⁺ B cells. Structural and functional characterization in a human chronic lymphocytic leukemia

1988 • 60 citations

Renal lesions in the “auto‐immune” mouse strains NZB and F1 NZB × NZW

1966 • 59 citations

Abnormalities in clonable B lymphocytes and myeloid progenitors in autoimmune NZB mice.

1979 • 59 citations

Antigen receptor-mediated B cell death is blacked by signaling via CD72 or treatment with dextran sukfate and is defective in autoimmunity-prone mice

1996 • 59 citations

Enhanced Antibody Response of Mice to Polyinosinic Polycytidylic Acid by Antithymocyte Serum and its Age-Dependent Loss in NZB/W Mice

1973 • 59 citations

Comparative Analysis of Natural Antibody Specificities among Hybridomas Originating from Spleen and Peritoneal Cavity of Adult NZB and BALB/c Mice

1988 • 59 citations

T-cell-receptor beta- and I-A beta-chain genes of normal SWR mice are linked with the development of lupus nephritis in NZB x SWR crosses.

1987 • 59 citations

Correction of T Cell Function by Thymosin in New Zealand Mice

1974 • 59 citations

Genetic studies of autoimmunity in New Zealand mice

1980 • 58 citations

Amyloidosis

1978 • 58 citations

Does the deletion within T cell receptor β‐chain gene of NZW mice contribute to autoimmunity in (NZB × NZW)F₁mice?

1986 • 58 citations

Ig heavy chain variable region gene complex of lupus mice exhibits normal restriction fragment length polymorphism.

1985 • 58 citations

Antigenic Specificity of Anti-Erythrocyte Autoantibody Responses by NZB Mice: Identification and Partial Characterization of Two Erythrocyte Surface Autoantigens

1972 • 57 citations

B cell participation in the recursive selection of T cell repertoires

1988 • 57 citations

Acquisition and maturation of expressed B cell repertoires in normal and autoimmune mice.

1988 • 57 citations

The pathogenesis of autoimmunity in New Zealand mice. II. Acceleration of glomerulonephritis by polyinosinic-polycytidylic acid.

1970 • 57 citations

Mapping of a gene for hypergammaglobulinemia to the distal region on chromosome 4 in NZB mice and its contribution to systemic lupus erythematosus in (NZB×NZW)F₁ mice

1994 • 56 citations

Proliferation of Ly‐1 B cells in autoimmune NZB and (NZB × NZW)F₁ mice

1987 • 55 citations

Class-specific regulation of anti-DNA antibody synthesis and the age-associated changes in (NZB x NZW)F1 hybrid mice.

1987 • 55 citations

The genetic basis of autoimmunity in NZB mice studied by progeny-testing.

1971 • 55 citations

The control of immune response in vitro by Ca2+. II. The Ca2+-dependent period during mitogenic stimulation.

1975 • 55 citations

Nutritional factors and autoimmunity. I. Immunopathology of zinc deprivation in New Zealand mice.

1981 • 55 citations

GENETIC CONTROL OF THE ANTIBODY RESPONSE TO TYPE III PNEUMOCOCCAL POLYSACCHARIDE IN MICE

1974 • 54 citations

Antibodies to RNA from autoimmune NZB/NZW mice recognize a similar antigenic determinant and show a large idiotypic diversity.

1982 • 54 citations

Isotypic profiles and other fine characteristics of immune responses to exogenous thymus-dependent and -independent antigens by mice with lupus syndromes.

1983 • 53 citations

Incidence of Antibodies to Double‐Stranded RNA in Systemic Lupus Erythematosus and Related Diseases

1971 • 53 citations

Immunofluorescence Studies on Thymocytotoxic Antibody from New Zealand Black Mice

1974 • 53 citations

Reciprocal T‐B determinant spreading develops spontaneously in murine lupus: implications for pathogenesis

1998 • 53 citations

A deficient development of the thymic epithelium and auto‐immune disease in NZB mice

1966 • 52 citations

Increased autoantibody production by NZB/NZW B cells in response to IL-5.

1988 • 52 citations

Adoptive transfer of the diseases of New Zealand black mice to normal mouse strains.

1969 • 51 citations

Resting B cells from New Zealand Black mice demonstrate a defect in apoptosis induction following surface IgM ligation.

1996 • 51 citations

Generation and characterization of cloned T helper cell lines for anti-DNA responses in NZB.H-2bm12 mice.

1992 • 50 citations

Changes in lymphoid populations of ageing CBA and NZB mice.

1971 • 50 citations

Mixed haplotypes and autoimmunity

1993 • 50 citations

Production of erythrocyte autoantibodies in NZB mice is inhibited by CD4 antibodies

1994 • 50 citations

DEFECTS IN HEMATOPOIETIC DIFFERENTIATION IN NZB AND NZC MICE

1971 • 50 citations

Linkage between immune response potential to DNA and X chromosome

1974 • 50 citations

The type of dietary fat affects the severity of autoimmune disease in NZB/NZW mice.

1987 • 50 citations

OBSERVATIONS ON NZB/B1 MICE

1964 • 50 citations

The Role of Somatic Mutation of Immunoglobulin Genes in Autoimmunity

1987 • 50 citations

Resting B cells from autoimmune lupus-prone New Zealand Black and (New Zealand Black x New Zealand White)F1 mice are hyper-responsive to T cell-derived stimuli.

1997 • 50 citations

Lymphocyte classes in New Zealand mice. II. Decreased frequency of immunoglobulin-bearing lymphocytes and increased frequency of lymphocytes lacking detectable theta or immunoglobulin determinants.

1972 • 50 citations

Allogeneic MHC antigen requirements for lupus-like autoantibody production and nephritis in murine graft-vs-host disease.

1988 • 50 citations

Genetic studies in NZB mice

1979 • 49 citations

Cellular Events Associated with the Immunogenesis of Anti‐Erythrocyte Autoantibody Responses of NZB Mice

1976 • 49 citations

Contributions ofEazandEbzMHC Genes to Lupus Susceptibility in New Zealand Mice

1998 • 49 citations

Brief Report: The Development of Lymphomas in Mice with Autoimmune Disorders Treated with Azathioprine

1968 • 49 citations

A hybridoma from an autoimmune NZB/NZW mouse producing monoclonal antibody to ribosomal-RNA.

1980 • 48 citations

Mendelian segregation of loci controlling xenotropic virus production in NZB crosses

1977 • 48 citations

Prostaglandin E1 treatment of NZB/W mice

1978 • 48 citations

The pathogenesis of autoimmunity in New Zealand mice

1990 • 47 citations

Aberrant cytokine expression and autocrine regulation characterize macrophages from young MRL+/+ and NZB/W F1 lupus-prone mice.

1997 • 47 citations

Dissection of the effects of tumor necrosis factor-alpha and class II gene polymorphisms within the MHC on murine systemic lupus erythematosus (SLE)

1998 • 46 citations

Proliferation of anti-DNA-producing NZB B cells in a non-autoimmune environment.

1986 • 46 citations

Effects of Administration of Monoclonal Antibodies (anti-CD4 or anti-CD8) on the Development of Autoimmune Diseases in (NZW × BXSB)F1 Mice

1998 • 46 citations

Quantitation and IgG subclass distribution of antichromatin autoantibodies in SLE mice

1988 • 46 citations

Genetic control of spontaneous and induced antierythrocyte autoantibody production in mice

1973 • 46 citations

Ig isotype switching in B lymphocytes. Isolation and characterization of clonal variants of the murine Ly-1+ B cell lymphoma, CH12, expressing isotypes other than IgM.

1988 • 45 citations

Genes determining autoimmune disease in New Zealand mice.

1981 • 45 citations

B lymphocyte lineage cells in newborn and very young NZB mice: evidence for regulatory disorders affecting B cell formation.

1983 • 45 citations

Age-dependent deficiency of B lymphocyte lineage precursors in NZB mice.

1982 • 45 citations

Anti-idiotypic antibodies to the Coombs antibody in NZB F1 mice.

1982 • 44 citations

B‐Lyl Cells: Immortal Ly‐1 ⁺ B Lymphocyte Cell Lines Spontaneously Arising in Murine Splenic Cultures

1986 • 44 citations

Transplantation of autoimmune potential. IV. Reversal of the NZB autoimmune syndrome by bone marrow transplantation.

1979 • 44 citations

Strain differences in the immune responses of mice. 3. A raised tolerance threshold in NZB thymus cells.

1971 • 44 citations

CD40‐mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus

1996 • 44 citations

Effects of Natural Thymocytotoxic Autoantibody of NZB Mice and of Specifically Prepared Antilymphocyte Serum on the Tissue Distribution of 51Cr-Labeled Lymphocytes

1973 • 43 citations

Sex differences in formation of anti-T-cell antibodies

1976 • 43 citations

Dysregulation of T Helper Cell Cytokines in Autoimmune Prone NZB x NZW Fl Mice

1995 • 43 citations

Age and genetic influence on immunity in NZB and autoimmune—Resistant mice

1976 • 42 citations

A New Red-Cell Autoantibody in NZB Mice

1965 • 42 citations

Carrier function in anti-hapten antibody responses. VI. Establishment of experimental conditions for either inhibitory or enhancing influences of carrier-specific cells on antibody production.

1973 • 42 citations

Primary in vitro cell-mediated lympholysis reaction of NZB mice against unmodified targets syngeneic at the major histocompatibility complex.

1978 • 41 citations

Precocious and enhanced functional maturation of B lineage cells in New Zealand Black mice during embryonic development.

1984 • 41 citations

Somatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 mice.

1988 • 41 citations

The inheritance of autoimmune disease in mice: a study of hybrids of the strains NZB and C3H

1964 • 41 citations

High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains.

1987 • 41 citations

Genetic studies in NZB mice. VI. Association of autoimmune traits in recombinant inbred lines.

1984 • 40 citations

Genetic Regulation of CD5⁺ B Cells in Autoimmune Disease and in Chronic Lymphocytic Leukemia

1992 • 40 citations

Genetic models of abnormal apoptosis in lymphocytes

1999 • 40 citations

The Effects of Dimethylsulfoxide, Dimethylform-Amide and Dimethylacetamide on the Cutaneous Barrier to Water in Human Skin**From the Institute of Dermatology, St. John's Hospital for Diseases of the Skin, Homerton Grove, London E.9, England.

1968 • 40 citations

The natural history of disease expression in CD4 and CD8 gene-deleted New Zealand black (NZB) mice.

1996 • 40 citations

Consequences of neonatal thymectomy in New Zealand black mice.

1967 • 39 citations

T cell receptor V_β genes expressed by IgG anti‐DNA autoantibody‐inducing T cells in lupus nephritis: Forbidden receptors and double‐negative T cells

1990 • 39 citations

Differentiation of B cell progenitorsin vitro: Generation of surface IgM+ B cells, including Ly-1 B cells, from Thy-l− asialoGM1+ cells in newborn liver

1987 • 39 citations

Antibodies to dissociated cerebellar cells in New Zealand mice as demonstrated by immunofluorescence

1978 • 39 citations

Genetic control of lymphocyte suppression. I. Lack of suppression in aged NZB mice is due to a B cell defect.

1978 • 39 citations

Differences in the repertoire expressed by peritoneal and splenic Ly-1 (CD5)+ B cells.

1990 • 39 citations

Effect of androgen therapy on survival and suppressor cell activity in aged NZB/NZW F1 hybrid mice.

1983 • 38 citations

In vivo effects of hyperdiploid Ly-1+ B cells of NZB origin.

1988 • 38 citations

Studies of congenitally immunologic mutant New Zealand mice. III. Growth of B lymphocyte clones in congenitally athymic (nude) and hereditarily asplenic (Dh/+) NZB mice: a primary B cell defect.

1979 • 38 citations

Antiproliferative mechanism of anti-Class II monoclonal antibodies

1989 • 38 citations

Treatment of lupus nephritis in adult (NZB + NZW)F1 mice by cortisone-facilitated tolerance to nucleic acid antigens.

1978 • 38 citations

Intrastrain recurrent idiotypes among anti‐DNA antibodies of (NZB X NZW)F₁ hybrid mice

1982 • 38 citations

IMMUNOGLOBULINS IN NZB/BL MICE

1968 • 37 citations

Inability of the NZB/NZW F1 Thymus to Transfer Cyclophos-Phamide-Induced Tolerance to Sheep Erythrocytes

1971 • 37 citations

Patterns of immune reactivity in autoimmune murine strains. I. Cell-mediated immune responses induced by H-2 indentical and H-2 incompatible stimulator cells.

1979 • 37 citations

Functional Deficiency of Splenic Adherent Cells in New Zealand Black Mice

1975 • 36 citations

The interaction of the xid and me genes.

1987 • 36 citations

Localization of spontaneously hyperactive B cells of NZB mice to a specific B cell subset.

1979 • 36 citations

Age-Associated Decline in the in Vitro Development of Cytotoxic Lymphocytes in NZB Mice

1976 • 36 citations

Successful treatment of autoimmune disease in (NZB/NZW)F1 female mice by using fractionated total lymphoid irradiation.

1979 • 36 citations

The regulatory role of NZB T lymphocytes in the production of anti-DNA antibodies in vitro.

1986 • 35 citations

Lymphocyte classes in New Zealand mice. I. Ontogeny and mitogen responsiveness of thymocytes and thymus-derived lymphocytes.

1972 • 35 citations

Mixed haplotype A beta Z/A alpha d class II molecule in (NZB x NZW)F1 mice detected by T cell clones.

1993 • 35 citations

Response of NZB mice to foreign antigen and development of autoimmune disease.

1969 • 35 citations

The age related responses of New Zealand mice to a murine sarcoma virus.

1971 • 34 citations

Plasmacytomas of the NZB Mouse

1978 • 34 citations

Differences in the Age-Dependent Release of a Low Molecular Weight Suppressor (LMWS) and Stimulators by Normal and NZB/W Lymphoid Organs

1976 • 34 citations

T and B lymphocytes in New Zealand black mice. An analysis of the theta, TL and MBLA markers.

1972 • 34 citations

The epigenetic influences of bone marrow and fetal liver stroma cells on the developmental potential of Ly‐1pro‐B lymphocyte clones

1989 • 33 citations

The Immune Response in NZB and NZB × C3H F1-Hybrid Mice as Measured by the Haemolysin Plaque Technique

1966 • 33 citations

Specificity in systemic lupus erythematosus of antibodies to double-stranded dna measured with the polyethylene glycol precipitation assay

1982 • 32 citations

Non-Antigenicity of Synthetic Polyribonucleotides and Apurinic Acid

1962 • 31 citations

The Lack of Thymic Influence in Regulating the Immune Response to Escherichia Coli 0127 Endotoxin

1972 • 31 citations

Regional Variation in the Deposition of Subepidermal Immunoglobulin in NZB/W F1 Mice: Association with Epidermal DNA Synthesis

1979 • 31 citations

Hydrocortisone Increases the Numbers of KL1⁺Cells, a Discrete Thymic Epithelial Cell Subset Characterized by High Molecular Weight Cytokeratin Expression

1988 • 29 citations

A naturally occurring antibody in New Zealand mice cytotoxic to dissociated cerebellar cells.

1978 • 28 citations

Ly-1 B helper cells in autoimmune "viable motheaten" mice.

1987 • 28 citations

Studies of congenitally immunologic mutant New Zealand mice. I. Autoimmune features of hereditarily asplenic (Dh/+) NZB mice; reduction of naturally occurring thymocytotoxic antibody and normal suppressor function.

1979 • 28 citations

High hepatic natural killer cell activity in murine lupus.

1987 • 28 citations

Reaction of the Reticular Tissue of Mice with Autoimmune Hæmolytic Anæmia to 2-Aminofluorene

1962 • 28 citations

Relative affinity of anti-protein antibodies in New Zealand mice.

1972 • 28 citations

Mechanism of allograft rejection in New Zealand mice. II. Role of a serum factor.

1974 • 28 citations

Similar in vivo expansion of B cells from normal DBA/2 and autoimmune NZB mice in xid recipients.

1987 • 28 citations

Study of thymic factors. II. Failure of thymosin to alter the natural history of nzb and nzb/nzw mice

1976 • 28 citations

The MIs system

1988 • 27 citations

Sex Differences in Survival of H-2 Incompatible Skin Grafts in Mice treated with Antithymocyte Serum

1970 • 27 citations

The disease of the NZB mouse. Examination of exchange ovum transplantation derived NZB and CFW mice.

1972 • 27 citations

Studies of congenitally immunologic mutant New Zealand mice. II. Absence of T cell progenitor populations and B cell defects of congenitally athymic (nude) New Zealand Black (NZB) mice.

1979 • 27 citations

Regulation of the immune response in autoimmune NZB/NZW F1 mice

1977 • 27 citations

AUTOIMMUNE DISEASE IN NZB/BL MICE

1966 • 27 citations

In vitro regulation of the pathogenic autoantibody response of New Zealand black mice. I. Loss with age of suppressive activity in T cell populations.

1985 • 27 citations

Developmental abnormalities of terminal deoxynucleotidyl transferase positive bone marrow cells and thymocytes in New Zealand mice: effects of prostaglandin E1.

1985 • 26 citations

Clonal Heterogeneity of the Anti-Erythrocyte Autoantibody Responses of NZB Mice

1974 • 26 citations

Activated B cells can deliver help for the in vitro generation of antiviral cytotoxic T cells.

1989 • 26 citations

The in vitro activity of peritoneal exudate cells from New Zealand black mice (NZB/B1) in the presence of I-125-BSA (bovine serum albumin).

1972 • 26 citations

Loss of CD23 Is a Consequence of B‐Cell Activation

1992 • 26 citations

Vascular changes in the kidneys of NZB mice and F1 NZBXNZW hybrids

1966 • 26 citations

Studies of congenitally immunologically mutant New Zealand mice. IV. Development of autoimmunity in congenitally athymic (nude) New Zealand Black x White F1 hybrid mice.

1980 • 25 citations

Polymorphism of the mouse TNF-i locus: sequence studies of the 3'-untranslated region and first intron

1993 • 25 citations

Endogenous C-type viruses: double agents in natural life processes.

1976 • 25 citations

Autoimmune Hemolytic Anemia in NZB/Bl Mice Treated with the Corticosteroid Drug Betamethasone

1965 • 25 citations

Natural murine autoantibodies and conventional antibodies exhibit similar degrees of antigenic cross-reactivity.

1988 • 25 citations

The effect of thymopoietin32-36 and ubiquitin on spontaneous immunopathology of New Zealand mice.

1979 • 25 citations

Erythrocyte survival in normal mice and in mice with autoimmune haemolytic anaemia.

1966 • 24 citations

Distinctive developmental origins and specificities of the CD5+B-cell subset

1996 • 24 citations

Injection of Alkaline Cations into Cat Spinal Motoneurones

1962 • 24 citations

Oncogene expression in autoimmune mice.

1985 • 23 citations

Idiotype-specific Ly-1 B cell-mediated helper activity: hybridomas that produce anti-idiotype antibody and nonimmunoglobulin lymphokine(s)1.

1987 • 23 citations

Specific Antigen-Binding and Antibody-Secreting Lymphocytes Associated with the Erythrocyte Autoantibody Responses of NZB and Genetically Unrelated Mice

1976 • 23 citations

T Cell Activation and Cellular Cooperation in Autoimmune NZB/NZW F1 Hybrid Mice

1975 • 23 citations

Myeloma proteins from NZB and BALB/c mice: structural and functional differences.

1979 • 23 citations

Genetic and cellular basis of anti-DNA antibody synthesis in systemic lupus erythematosus of New Zealand mice.

1987 • 23 citations

Cold Reacting Antibody in NZB/Bl Mice

1970 • 23 citations

Suppressor T cells and self-tolerance. Active suppression required for normal regulation of anti-erythrocyte autoantibody responses in spleen cells from nonautoimmune mice.

1988 • 23 citations

Specificity of natural thymocytotoxic autoantibody developed in New Zealand black mice.

1980 • 22 citations

CORTISONE ACETATE TREATMENT OF HAEMOLYTIC ANAEMIA IN NZB MICE

1965 • 22 citations

Failure of NZB Spleen to Respond to Prethymic Bone Marrow Suppressor Cells

1979 • 22 citations

Elution of antinuclear factor from renal lesions of NZB-NZW mice.

1968 • 22 citations

B220- bone marrow progenitor cells from New Zealand black autoimmune mice exhibit an age-associated decline in Pre-B and B-cell generation

1995 • 22 citations

Signaling to a B-cell clone by Ek, but not Ak, does not reflect alteration of A k genes

1988 • 21 citations

Independent Analysis of T Helper and T Killer Cell Function in Young and Old NZB Mice

1978 • 21 citations

Comparison of T cell-mediated immune responsiveness of NZB, (NZB x &NZW)F1 hybrid and other murine strains.

1977 • 20 citations

Monoclonal antibody directed to a Hanganutziu-Deicher active ganglioside, GM2 (NeuGc)

1988 • 20 citations

Suppression of NZB/NZW Murine Nephritis by Administration of a Syngeneic Monoclonal Antibody to DNA

1983 • 20 citations

Induction of Autoimmune Hemolytic Disease by Diffusible Substances from the Thymus of NZB/Bl Mice

1967 • 20 citations

Association of defective feedback suppressor t cell activity with autoimmunity in nzb mice

1978 • 20 citations

Development of Ly-1+ B cells in immunodeficient CBA/N mice.

1987 • 20 citations

Effect of 89Sr on immunity and autoimmunity in NZB/NZW F1 mice.

1980 • 20 citations

Hyper-responsiveness in NZB mice to the experimental induction of anti-red cell autoantibody.

1977 • 20 citations

Characterization of the spontaneous autoimmune (anti-erythrocyte) response in NZB mice using a pathogenic monoclonal autoantibody and its anti-idiotype.

1989 • 20 citations

Age-related decline in the antibody response to E. coli lipopolysaccharide in New Zealand Black mice.

1975 • 19 citations

Characterization of the immunodeficiency of RIIS/J [corrected] mice. I. Association with the CD5 (LY-1) [corrected] B cell lineage.

1989 • 19 citations

Antinuclear factor in NZB-NZW mice: incidence and in vitro effects.

1968 • 19 citations

The E-linked subregion of the major histocompatability complex down-regulates autoimmunity in NZB x NZW F1 mice

1994 • 19 citations

Properties of tRNA-Specific Antibodies from NZB/NZW Mice

1977 • 19 citations

Effects of transgenic mixed-haploptype MHC class II molecules A_α^dA_β^z on autoimmune disease in New Zealand mice

1996 • 19 citations

Age-related natural antibody specificities among hybridoma clones originating from NZB spleen.

1987 • 18 citations

IdLNF1-Specific T Cell Clones Accelerate the Production of IdLNF1+ IgG and Nephritis in SNF1Mice

1995 • 18 citations

Immunobiology of the autoantibody response. I. Circulating analogues of erythrocyte autoantigens and heterogeneity of the autoimmune response of NZB mice.

1973 • 18 citations

IL 1-like activities present in murine amniotic fluid. A significantly larger amount of IL 1 beta-like activity is present in the amniotic fluid of autoimmune NZB mice.

1987 • 18 citations

Suppression of murine lupus erythematosus by Dactinomycin

1976 • 17 citations

Murine autoimmune hemolytic anemia induced via xenogeneic erythrocyte immunization

1979 • 17 citations

Genetic aspects of immunologic abnormalities in New Zealand mouse strains

1978 • 17 citations

B cell hyperresponsiveness to interleukin 2 and the age-associated decline in murine lupus

1989 • 17 citations

Comparative study of V_H gene family usage by newborn xid and non‐xid mice, newborn NZB and adult NZB mice, and by splenic and peritoneal cavity B cell compartments

1988 • 17 citations

Influence of Autoimmune Hemolytic Anemia on Susceptibility to Salmonella Infection.

1964 • 16 citations

Evidence for an Abnormal Microenvironment in the Thymus of New Zealand Black Mice

1975 • 16 citations

Preferential lysis of undifferentiated thymocytes by natural thymocytotoxic antibodies from New Zealand black mice.

1980 • 16 citations

FUNCTIONAL CHARACTERIZATION OF A NATURALLY OCCURRING ANTIBODY CYTOTOXIC FOR A SUBPOPULATION OF SPLENIC T CELLS

1976 • 16 citations

In Vitro and in Vivo Cytotoxicity to EL-4 Sarcoma in New Zealand Mice

1974 • 16 citations

Suppressor cells and immunodeficiency in (NZB × NZW)F1 hybrid mice

1979 • 16 citations

Functional double‐negative T cells in the periphery express T cell receptor Vβ gene products that cause deletion of single‐positive T cells

1993 • 16 citations

Studies on the influence of the internal environment on autoantibody production by B cells

1988 • 16 citations

Decreased Response of Cultured New Zealand Mouse Spleen Cells to Sheep Erythrocytes

1974 • 16 citations

THE INFLUENCE OF SPLENECTOMY IN NZB MICE

1963 • 16 citations

Effect of altered lymphocyte function on immunologic disorders in nzb/nzw mice.

1978 • 16 citations

Suppression of antibodies to nucleic acids with polyinosinic-polycytidylic acid and cyclophosphamide in murine lupus.

1970 • 15 citations

Abnormalities of B lineage cells are demonstrable in long term lymphoid bone marrow cultures of New Zealand black mice.

1987 • 15 citations

EARLY AUTOANTIBODY FORMATION IN LETHALLY IRRADIATED OR DRUG-TREATED H-2-COMPATIBLE RECIPIENTS OF PRE-AUTO-IMMUNE NZB BONE MARROW OR FETAL LIVER CELLS

1974 • 15 citations

Responses to T-cell and B-cell mitogens in autoimmune Palmerston North and mice

1984 • 15 citations

Immunological regulation of spontaneous antibodies to DNA and RNA. III. Early effects of neonatal thymectomy and splenectomy.

1977 • 15 citations

T cell differentiation and the congenitally athymic (nude) mouse

1977 • 15 citations

Surface and functional characteristics of B cells from lupus-prone murine strains

1982 • 14 citations

F(ab′)2 anti-CD4 and intact anti-CD4 monoclonal antibodies inhibit the accumulation of CD4+ T cells, CD8+ T cells, and B cells in the kidneys of lupus-prone NZB/NZW mice

1990 • 14 citations

6‐MERCAPTOPURINE ADMINISTRATION TO NZB MICE

1968 • 14 citations

Ability of NZW but not NZB antigen-presenting cells to support T cell proliferative response to DNA methylated albumin.

1980 • 13 citations

Effect of anti‐Ia treatment on the production of anti‐DNA antibody by NZB mice

1986 • 13 citations

Defective B cell clonal regulation and autoantibody production in New Zealand black mice.

1987 • 13 citations

An in vitro system for the generation of suppressor cells and the requirement for B cells in their induction.

1985 • 13 citations

Establishment and characterization of cloned CD4− CD8−αβ-T cell receptor (TCR)-bearing autoreactive T cells from autoimmune NZB×NZW F1 mice

1997 • 12 citations

Abnormal responses to ingested substances in murine systemic lupus erythematosus: apparent effect of a casein-free diet on the development of systemic lupus erythematosus in NZB/W mice.

1987 • 12 citations

Effect of Genetic Background onEαdTransgene-mediated Protection from Murine Lupus

1998 • 12 citations

Active role of T cells in promoting an in vitro autoantibody response to self erythrocytes in NZB mice.

1988 • 12 citations

Membrane Immunoglobulins of Lymphocytes in NZB Mice

1971 • 12 citations

Reaction of mouse strains to skin test for ectromelia using an allied virus as inoculum

1975 • 12 citations

Natural cytotoxic cells in NZB mice: Spontaneous in vivo and in vitro primed activity and structural characteristics

1979 • 12 citations

Hyperactive T-cell function in young NZB mice; increased proliferative responses to allogenic cells.

1976 • 12 citations

Alteration of lymphocyte function in nzb/nzw mice

1979 • 12 citations

Differential susceptibility to tolerance induction in vitro of splenic B cells from several transgenic mouse lines. Role of B1 cells.

1995 • 11 citations

Shared idiotypes on anti-DNA and anti-poly (ADP-ribose) antibodies.

1988 • 11 citations

Phathogenesis of autoimmune hemolytic anemia in New Zealand Black mice

1994 • 11 citations

Murine autoimmune hemolytic anemia induced via xenogeneic erythrocyte immunization

1981 • 11 citations

A peripheral and central T cell antigen recognized by a monoclonal thymocytotoxic autoantibody from New Zealand black mice.

1987 • 11 citations

Murine autoimmune hemolytic anemia induced via xenogeneic erythrocyte immunization

1979 • 11 citations

Immunopathology of New Zealand Black mice treated with antilymphocyte globulin.

1971 • 11 citations

Regulation of antigen presentation. II. Anti-Ig and IL-2 induce IL-1 production by murine splenic B cells.

1989 • 11 citations

Characteristics of a spontaneous monoclonal thymocytotoxic antibody from New Zealand black mice: recognition of a specific NTA determinant

1984 • 11 citations

Igh-C allotype-linked control of anti-DNA production and clonotype expression in mice infected with Plasmodium yoelii.

1988 • 11 citations

Normal tolerance characteristics of the antibody-forming cell precursors of the NZB mouse.

1973 • 11 citations

Tissue localization and biochemical characteristics of a new thymic antigen recognized by a monoclonal thymocytotoxic autoantibody from New Zealand black mice.

1985 • 10 citations

Functional CD4⁺T cell subsets defined by expression of CD45RC and NTA260 antigens and age-associated polarization in murine lupus

1995 • 10 citations

Aberrant maturational characteristics of the immune responses of NZB mice to autologous and heterologous erythrocyte antigens

1975 • 10 citations

Synthesis of prostaglandin E by peritoneal macrophages from NZB/W mice

1988 • 10 citations

The kidneys of NZB/B1, NZO/B1, NZC/B1 and NZY/B1 mice

1971 • 10 citations

Spontaneous carditis in the NZB mouse and its hybrids

1974 • 10 citations

Analysis of T cell and B cell function in Peyer's patch and lamina propria of New Zealand Black and DBA/2 mice.

1986 • 10 citations

Renal disease in (NZB x NZW)F1 hybrid mice treated with anti-lymphocytic antibody.

1970 • 10 citations

Requirements for suppressor cell activation. Role of accessory cells.

1989 • 9 citations

Relative avidity of antibodies towards sheep red blood cells in New Zealand Black mice.

1974 • 9 citations

Defects in antigen-specific immune tolerance in continuous B cell lines from autoimmune mice.

1986 • 9 citations

Suppressor Cell Activation by Anti-Thy 1.2 in NZB/WF1 Mice

1977 • 9 citations

Proliferative activity in the lymphatic tissues of germ‐free New Zealand Black mice

1970 • 9 citations

Cell-mediated autoimmunity in NZB mice.

1973 • 9 citations

Comparisons of Myeloma Proteins from NZB and BALB/c Mice: Structural and Functional Differences of Heavy Chains

1979 • 9 citations

The role of suppressor T cells in the expression of autoimmune haemolytic anaemia in NZB mice.

1981 • 9 citations

Multigenic basis of autoimmune disease in New Zealand mice.

1987 • 9 citations

Autoantibodies against the inner aspect of erythrocyte membranes in NZB mice.

1977 • 8 citations

Prolonged survival of hypertransfused NZB/NZW mice.

1977 • 8 citations

The spontaneous development of thymocytotoxic antibodies in athymic nude mice and its suppression after transfer of syngeneic thymocytes

1978 • 8 citations

Bone marrow cells from young and old New Zealand Black mice can reconstitute B lymphocytes in Severe Combined Immunodeficient recipients

1989 • 8 citations

Autoimmune Cell-Mediated Responses: Spontaneous Responses to Syngeneic Cells in NZB/NZW F1 Mice

1979 • 7 citations

Elevation of plasma fibronectin and serum amyloid P in autoimmune NZB, , and mice

1988 • 7 citations

Studies of immune responses in mice prone to autoimmune disorders

1986 • 7 citations

Anti-CD4 treatment of NZB mice prevents the development of erythrocyte autoantibodies but hastens the appearance of anaemia

1994 • 7 citations

Transferred B cells from autoimmune NZB/N mice fail to activate T suppressor cells

1987 • 7 citations

Hemopoietic cell dysfunction in murine lupus.

1987 • 7 citations

Neoplastic behavior of chromosomally abnormal clones in New Zealand black mice

1978 • 7 citations

Aberrant maturation of the immune response to the thymus-independent antigen DNP-Lys-Ficoll by New Zealand black mice

1980 • 7 citations

The presence of autoantibodies specific for NZB serum factors in adult NZB mice and the establishment of monoclonal autoantibodies against these humoral factors

1988 • 7 citations

Strain Differences in the Liver Autoantibody Response of Inbred Mice

1969 • 7 citations

Studies of immune responses in mice prone to autoimmune disorders

1983 • 7 citations

Distribution of lymphocytes identified by surface markers in murine strains with sle-like syndromes. Abstr.

1979 • 7 citations

The incidence of spontaneously occurring anti-liver antibodies in New Zealand black mice.

1969 • 6 citations

Study of Autoimmune Disease in New Zealand Mice

1968 • 6 citations

Isolation and Functional Characterization of IL-2 Responsive T cell Clones from NZB×NZW F1 Mice

1996 • 6 citations

Effect of partial testosterone replacement or thymosin on anti-DNA in castrated (NZB × NZW)F1 males

1987 • 6 citations

Immunoglobulins in mice

1974 • 6 citations

Lymphocyte subpopulations in the thymus of NZB x NZW mice: phenotypic characterization by flow cytofluorometry analysis.

1982 • 6 citations

The failure to transfer the NZB disease following implantation of NZB thymus‐containing chambers

1973 • 6 citations

Role of T cells in regulating expression of the B cell repertoire. Anti-ssDNA precursor frequency of DBA/2 B cells is increased in the presence of T cells from NZB mice.

1988 • 6 citations

Mast cell incidence and cell proliferation in the lymphoid organs of NZB mice.

1969 • 6 citations

In vitro studies on the phagocytosis of Staphylococcus aureus by peritoneal macrophages of New Zealand mice.

1973 • 6 citations

Dependency of B Cells on the Presence of Adherent Cells, or Factors Derived from Them, for the Production of Autoantibodies in Vitro in the Absence of Cell Division

1986 • 6 citations

1-Methylisatin 3-thiosemicarbazone treatment of NZB x NZW hybrid mice.

1971 • 6 citations

B‐1^a and conventional B cells from autoimmune NZB. H‐2^bm12 mice exhibit similar functional characteristics in vivo

1993 • 6 citations

B cell repertoire for anti-DNA antibody in normal and lupus mice: differential expression of precursor cells for high and low affinity anti-DNA antibodies.

1988 • 5 citations

STATOLON IN MURINE AUTOIMMUNE DISEASE

1968 • 5 citations

Chromosome breakage and xenotropic C-type virus in embryonic cultures from New Zealand black mice

1979 • 5 citations

Impairment of primary in vitro response of New Zealand mouse spleen cells to a thymic-dependent antigen

1977 • 5 citations

Effect of an autoreactive T cell clone from (NZB × NZW)F1 mice on the production of anti-DNA antibodies in vivo and in vitro

1988 • 5 citations

Relationship of Subepidermal Immune Complex to Renal Deposits in the (NZB × W) F<sub>1</sub> Mouse

1976 • 5 citations

The relationship between the defect in the syngeneic mixed lymphocyte reaction and thymic abnormality in New Zealand mice.

1987 • 5 citations

Serum Proteins in NZB/B1 and Related Strains of Mice.

1966 • 5 citations

Possible involvement of Ly-1 B cells in the effector phase of IgG suppression mediated by suppressor T cell factor.

1987 • 4 citations

Characterization of two molecules at 30,33 kDa as major target antigens of natural thymocytotoxic autoantibodies

1988 • 4 citations

The effects of macrophages on interleukin 2 production in thymocytes of New Zealand black mice.

1987 • 4 citations

The role of autoreactive T-cell hybridomas from autoimmune model mice.

1988 • 4 citations

An antibody to isogeneic fibroblasts in the serum of diseased NZB mice.

1974 • 4 citations

Sensitivity of pre-T cells to natural thymocytotoxic autoantibodies developed in New Zealand Black mice.

1982 • 4 citations

Effect of interferon-γ on the abnormality of T cell activation in NZB mice

1988 • 3 citations

Immunoregulatory effects of cloned T cells on B-cell responses: comparison of autoimmune and non-autoimmune derived clones.

1989 • 3 citations

In vitro immune response of cells of various lymphoid tissues in (NZB X NZW)F1 mice: evidence for abnormality of the mesenteric lymph node cells.

1984 • 3 citations

Cytotoxic reactions of nzb spleen cells with lymphocytes of mhc identical strains. Abstr.

1978 • 3 citations

Effects of Neonatal Thymectomy on Spontaneous Murine Autoimmune Disease.

1967 • 3 citations

Proteins associated with B lymphocyte hyperactivity in New Zealand black mice.

1987 • 3 citations

Cell surface autoantigenic expressions and their circulating analogues in the pathogenesis of immune injury in nzb mice. Abstr.

1972 • 2 citations

Defective B-cell tolerance in New Zealand black mice

1988 • 2 citations

Decreased natural killer-type activity of spleen cells against immature thymocytes in autoimmune strains of mice.

1985 • 2 citations

Increased Helper Cell Activity of NZB Mice against H-2-Identical Allogeneic Cells

1988 • 2 citations

Changes in the compositions of the null cell compartment with murine autoimmunity

1983 • 2 citations

Deleted Work

1955 • 0 citations