Restricted expression of membrane type 1‐matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1993 • 2,169 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover

1999 • 1,280 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation

1996 • 741 citations

Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration

2001 • 732 citations

Matrix Metalloproteinases Regulate Neovascularization by Acting as Pericellular Fibrinolysins

1998 • 716 citations

Matrix metalloproteinases: multifunctional contributors to tumor progression

2000 • 639 citations

Regulation of Cell Invasion and Morphogenesis in a Three-Dimensional Type I Collagen Matrix by Membrane-Type Matrix Metalloproteinases 1, 2, and 3

2000 • 588 citations

Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response.

1996 • 515 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

Membrane‐Type Matrix Metalloproteinases 1 and 2 Exhibit Broad‐Spectrum Proteolytic Capacities Comparable to Many Matrix Metalloproteinases

1997 • 434 citations

Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.

1993 • 428 citations

The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells.

1995 • 425 citations

Myofibroblasts in human granulation tissue

1974 • 385 citations

Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion

2001 • 382 citations

In Vivo Evidence That the Stromelysin-3 Metalloproteinase Contributes in a Paracrine Manner to Epithelial Cell Malignancy

1998 • 290 citations

Factors influencing myofibroblast differentiation during wound healing and fibrosis.

1995 • 273 citations

MT1‐MMP expression promotes tumor growth and angiogenesis through an up‐regulation of vascular endothelial growth factor expression

2002 • 254 citations

Inhibition of Collagenolytic Activity and Metastasis of Tumor Cells by a Recombinant Human Tissue Inhibitor of Metalloproteinases

1990 • 233 citations

Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a.

1987 • 226 citations

Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface

1998 • 223 citations

Processing of Integrin αv Subunit by Membrane Type 1 Matrix Metalloproteinase Stimulates Migration of Breast Carcinoma Cells on Vitronectin and Enhances Tyrosine Phosphorylation of Focal Adhesion Kinase

2002 • 212 citations

Regulation of Membrane‐Type Matrix Metalloproteinase‐1 Expression by Growth Factors and Phorbol 12‐Myristate 13‐Acetate

1996 • 184 citations

Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.

1997 • 177 citations

Mutation Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP)

2001 • 158 citations

Up-regulation of vascular endothelial growth factor by membrane-type 1 matrix metalloproteinase stimulates human glioma xenograft growth and angiogenesis.

2002 • 157 citations

Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions.

1997 • 137 citations

Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas.

2001 • 135 citations

Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: Quantificative and morphological analyses

1997 • 133 citations

Membrane-type metalloproteinases in tumor invasion

1998 • 127 citations

Activation of the extracellular signal‐regulated protein kinase (ERK) cascade by membrane‐type‐1 matrix metalloproteinase (MT1‐MMP)

2001 • 124 citations

Emerging roles for proteinases in cancer.

1997 • 123 citations

High levels of TIMP-2 correlate with adverse prognosis in breast cancer

2000 • 123 citations

The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion.

2001 • 118 citations

MT-MMP expression and localisation in human lung and breast cancers

1996 • 112 citations

Messenger RNA for urokinase plasminogen activator is expressed in myofibroblasts adjacent to cancer cells in human breast cancer.

1996 • 110 citations

Membrane Type 1 Matrix Metalloproteinase-associated Degradation of Tissue Inhibitor of Metalloproteinase 2 in Human Tumor Cell Lines

2000 • 101 citations

Stromelysin-3 expression promotes tumor take in nude mice.

1996 • 92 citations

Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy

1994 • 82 citations

The Capacity of Retracting a Collagen Matrix Is Lost by Dermatosparactic Skin Fibroblasts

1983 • 78 citations

Plasma membrane‐dependent activation of gelatinase A in human vascular endothelial cells

1995 • 69 citations

Smooth muscle differentiation in cultured human breast gland stromal cells.

1990 • 67 citations

Type IV Collagen Induces Matrix Metalloproteinase 2 Activation in HT1080 Fibrosarcoma Cells

2000 • 66 citations

Identification, paracrine generation, and possible function of human breast carcinoma myofibroblasts in culture

1992 • 61 citations

Coordinate enhancement of gelatinase a mRNA and activity levels in human fibroblasts in response to breast‐adenocarcinoma cells

1994 • 58 citations

Expression of membrane type 1 matrix metalloproteinase (MT1‐MMP) in A2058 melanoma cells is associated with MMP‐2 activation and increased tumor growth and vascularization

2001 • 55 citations

Stromelysin-3 mRNA Associated with Myofibroblasts Is Overexpressed in Aggressive Basal Cell Carcinoma and in Dermatofibroma but Not in Dermatofibrosarcoma

1996 • 53 citations

Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy

1994 • 43 citations

Presence of high levels of MT1-MMP protein in fibroblastic cells of human invasive carcinomas

1999 • 39 citations

Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells.

1997 • 37 citations

Selective Culture of Epithelial Cells from Primary Breast Carcinomas Using Irradiated 3T3 Cells as Feeder Layer

2001 • 19 citations

[The role of matrix metalloproteinases in cancer invasion and metastasis].

1997 • 1 citations

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