Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: Quantificative and morphological analyses

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity

1996 • 392 citations

The collagenase gene family in humans consists of at least four members

1988 • 364 citations

The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis

1994 • 333 citations

Expression of membrane-type matrix metalloproteinase in human gastric carcinomas

1995 • 267 citations

Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP‐2 in lung carcinomas correlates with the expression of membrane‐type matrix metalloproteinase (MT‐MMP) and with lymph node metastasis

1995 • 267 citations

Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3.

1994 • 217 citations

Expression of collagenase‐related metalloproteinase genes in human lung or head and neck tumours

1991 • 210 citations

Tumor and stromal expression of matrix metalloproteinases and their role in tumor progression.

1994 • 200 citations

High level of MT-MMP expression is associated with invasiveness of cervical cancer cells

1996 • 165 citations

Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase.

1992 • 153 citations

Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas

1992 • 143 citations

The 28-kDa N-terminal domain of mouse stromelysin-3 has the general properties of a weak metalloproteinase

1993 • 132 citations

MT-MMP expression and localisation in human lung and breast cancers

1996 • 112 citations

Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.

1995 • 101 citations

Stromelysin-3 is overexpressed by stromal elements in primary non-small cell lung cancers and regulated by retinoic acid in pulmonary fibroblasts.

1995 • 83 citations

Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.

1994 • 81 citations

Genes of laminin B1 chain, alpha 1 (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas.

1993 • 51 citations

Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy

1994 • 43 citations

Primary mucinous cystadenocarcinoma of the retroperitoneum

1995 • 39 citations