Rhoa Function in Lamellae Formation and Migration Is Regulated by the α6β4 Integrin and Camp Metabolism

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1999 • 1,558 citations

Rho GTPases Control Polarity, Protrusion, and Adhesion during Cell Movement

1999 • 1,452 citations

Rac Downregulates Rho Activity

1999 • 840 citations

Bidirectional signaling between the cytoskeleton and integrins

1999 • 765 citations

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

1997 • 746 citations

Activation of Phosphoinositide 3-OH Kinase by the α6β4 Integrin Promotes Carcinoma Invasion

1997 • 615 citations

An essential part for Rho–associated kinase in the transcellular invasion of tumor cells

1999 • 609 citations

Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes.

1996 • 560 citations

Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling

1997 • 448 citations

Desmosomes and hemidesmosomes: structure and function of molecular components

1996 • 350 citations

Phosphorylation of Adducin by Rho-Kinase Plays a Crucial Role in Cell Motility

1999 • 300 citations

The integrin alpha 6 beta 4 is a laminin receptor.

1992 • 299 citations

Effects of Regulated Expression of Mutant RhoA and Rac1 Small GTPases on the Development of Epithelial (MDCK) Cell Polarity

1998 • 297 citations

The 70 kDa S6 Kinase Complexes with and Is Activated by the Rho Family G Proteins Cdc42 and Rac1

1996 • 293 citations

cAMP-induced Morphological Changes Are Counteracted by the Activated RhoA Small GTPase and the Rho Kinase ROKα

1998 • 267 citations

N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells.

1979 • 261 citations

Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.

1994 • 245 citations

The Integrin α6β4 Functions in Carcinoma Cell Migration on Laminin-1 by Mediating the Formation and Stabilization of Actin-containing Motility Structures

1997 • 241 citations

Protein Kinase C–Dependent Mobilization of the α6β4 Integrin from Hemidesmosomes and Its Association with Actin-Rich Cell Protrusions Drive the Chemotactic Migration of Carcinoma Cells

1999 • 214 citations

Hemidesmosomes: roles in adhesion, signaling and human diseases

1996 • 213 citations

Elevation of Intracellular cAMP Inhibits RhoA Activation and Integrin-dependent Leukocyte Adhesion Induced by Chemoattractants

1997 • 205 citations

rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells.

1994 • 171 citations

Small GTP-binding Protein Rho Stimulates the Actomyosin System, Leading to Invasion of Tumor Cells

1998 • 160 citations

Release of cAMP Gating by the α6β4 Integrin Stimulates Lamellae Formation and the Chemotactic Migration of Invasive Carcinoma Cells

1998 • 156 citations

Requirement for Rho in Integrin Signalling

1997 • 127 citations

Intestinal epithelial restitution. Involvement of specific laminin isoforms and integrin laminin receptors in wound closure of a transformed model epithelium.

1997 • 95 citations

rac p21 Is Involved in Insulin-Induced Membrane Ruffling and rho p21 Is Involved in Hepatocyte Growth Factor- and 12-O-Tetradecanoylphorbol-13-Acetate (TPA)-Induced Membrane Ruffling in KB Cells

1994 • 39 citations