The integrin alpha 6 beta 4 is a laminin receptor.

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma

1982 • 1,225 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits.

1987 • 727 citations

Laminin receptor on platelets is the integrin VLA-6

1988 • 679 citations

Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo.

1992 • 669 citations

Regulated expression and binding of three VLA (β1) integrin receptors on T cells

1990 • 634 citations

Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.

1991 • 574 citations

Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.

1990 • 486 citations

Distinct functions for integrins alpha 3 beta 1 in focal adhesions and alpha 6 beta 4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: relation to hemidesmosomes.

1990 • 462 citations

Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations.

1991 • 447 citations

Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.

1990 • 405 citations

The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.

1990 • 375 citations

A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody.

1987 • 334 citations

Antibodies to the conserved cytoplasmic domain of the integrin beta 1 subunit react with proteins in vertebrates, invertebrates, and fungi.

1988 • 323 citations

Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4.

1990 • 323 citations

A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

1989 • 314 citations

The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin.

1990 • 288 citations

Association of the VLA a Subunit with a Novel Protein

1989 • 285 citations

Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain.

1990 • 278 citations

N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells.

1979 • 261 citations

The major non-integrin laminin binding protein of macrophages is identical to carbohydrate binding protein 35 (Mac-2).

1990 • 260 citations

Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.

1990 • 249 citations

Polarized integrin mediates human keratinocyte adhesion to basal lamina.

1990 • 216 citations

Cell-surface regulation of β1-integrin activity on developing retinal neurons

1991 • 191 citations

The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin.

1991 • 164 citations

Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation.

1991 • 160 citations

Human microvascular endothelial cells use beta 1 and beta 3 integrin receptor complexes to attach to laminin.

1990 • 155 citations

Altered expression in squamous carcinoma cells of an orientation restricted epithelial antigen detected by monoclonal antibody A9.

1986 • 139 citations

The A9 Antigen Associated with Aggressive Human Squamous Carcinoma Is Structurally and Functionally Similar to the Newly Defined Integrin α6β4

1991 • 130 citations

Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines.

1988 • 128 citations

Human colon carcinoma cells use multiple receptors to adhere to laminin: involvement of alpha 6 beta 4 and alpha 2 beta 1 integrins.

1990 • 127 citations

Basement membrane diversity detected by monoclonal antibodies

1984 • 121 citations

Altered Antigen Expression Predicts Outcome in Squamous Cell Carcinoma of the Head and Neck

1990 • 100 citations

Expression of tumor antigen correlated with metastatic potential of Lewis lung carcinoma and B16 melanoma clones in mice.

1986 • 95 citations

The high‐affinity binding of laminin to cells

1989 • 83 citations

The internal affairs of an integrin

1991 • 77 citations

Laminin binding proteins

1991 • 72 citations

Asn-linked oligosaccharide-dependent interaction between laminin and gp120/140. An alpha 6/beta 1 integrin.

1991 • 64 citations

Relationship between extracellular matrix interactions and degree of differentiation in human colon carcinoma cell lines.

1989 • 60 citations

The A9 antigen associated with aggressive human squamous carcinoma is structurally and functionally similar to the newly defined integrin alpha 6 beta 4.

1991 • 48 citations