Tumor Necrosis Factor

The Bcl2 family: regulators of the cellular life-or-death switch

2002 • 3,782 citations

The TNF and TNF Receptor Superfamilies

2001 • 3,533 citations

AP-1 as a regulator of cell life and death

2002 • 2,752 citations

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1998 • 2,698 citations

NF-κB at the crossroads of life and death

2002 • 2,684 citations

Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

2003 • 2,545 citations

Tumor necrosis factor signaling

2003 • 2,262 citations

TNF-R1 Signaling: A Beautiful Pathway

2002 • 1,860 citations

IAP proteins: blocking the road to death's door

2002 • 1,753 citations

The JNK signal transduction pathway

2002 • 1,520 citations

Failure to Regulate TNF-Induced NF-κB and Cell Death Responses in A20-Deficient Mice

2000 • 1,374 citations

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

2002 • 1,325 citations

The CD95(APO-1/Fas) DISC and beyond

2003 • 1,064 citations

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

2003 • 1,045 citations

A physical and functional map of the human TNF-α/NF-κB signal transduction pathway

2004 • 993 citations

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

2002 • 699 citations

A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

2003 • 557 citations

The Bax Subfamily of Bcl2-Related Proteins Is Essential for Apoptotic Signal Transduction by c-Jun NH₂-Terminal Kinase

2002 • 463 citations

Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway

2002 • 448 citations

Activation of the JNK signaling pathway: Breaking the brake on apoptosis

2002 • 432 citations

Characterization of XIAP-Deficient Mice

2001 • 425 citations

Regulation of lymphocyte proliferation and death by flip

2001 • 385 citations

Human De-Etiolated-1 Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase

2004 • 367 citations

Evolution of TNF Signaling Mechanisms

2002 • 359 citations

The Ubiquitin Ligase SCF ^Fbw7 Antagonizes Apoptotic JNK Signaling

2004 • 345 citations

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

2003 • 288 citations

JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD

2004 • 278 citations

JunD Mediates Survival Signaling by the JNK Signal Transduction Pathway

2003 • 253 citations

Wengen, a Member of the Drosophila Tumor Necrosis Factor Receptor Superfamily, Is Required for Eiger Signaling

2002 • 189 citations

Drosophila AP-1: lessons from an invertebrate

2001 • 139 citations

JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways

2003 • 63 citations