The secretory pathway: mechanisms of protein sorting and transport

Protein folding in the cell

1992 • 4,138 citations

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

The Biogenesis of Lysosomes

1989 • 1,583 citations

The ancient regulatory-protein family of WD-repeat proteins

1994 • 1,478 citations

COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

1994 • 1,294 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

BIOSYNTHETIC PROTEIN TRANSPORT AND SORTING BY THE ENDOPLASMIC RETICULUM AND GOLGI

1987 • 985 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Cell Surface Polarity in Epithelia

1985 • 880 citations

Immunoglobulin heavy chain binding protein

1983 • 849 citations

Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes.

1986 • 847 citations

INTRACELLULAR TRANSPORT OF SECRETORY PROTEINS IN THE PANCREATIC EXOCRINE CELL

1967 • 841 citations

Signal Sequence Recognition and Protein Targeting to the Endoplasmic Reticulum Membrane

1994 • 821 citations

The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations.

1989 • 819 citations

Cholesterol and the Golgi Apparatus

1993 • 819 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 808 citations

Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.

1994 • 798 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

1994 • 793 citations

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

1992 • 741 citations

Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

1992 • 736 citations

Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway

1990 • 721 citations

Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin

1993 • 716 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

1984 • 689 citations

Quality control in the secretory pathway

1995 • 679 citations

Protein degradation in the endoplasmic reticulum

1990 • 659 citations

The syntaxin family of vesicular transport receptors

1993 • 656 citations

Secretory protein translocation across membranes—the role of the ‘docking protein’

1982 • 648 citations

Vesicle fusion from yeast to man

1994 • 635 citations

Progress in Unraveling Pathways of Golgi Traffic

1985 • 615 citations

ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein

1991 • 604 citations

Specificity and regulation of a synaptic vesicle docking complex

1994 • 601 citations

Implications of the SNARE hypothesis for intracellular membrane topology and dynamics

1994 • 582 citations

SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast

1990 • 578 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

1989 • 570 citations

ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway

1990 • 548 citations

Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum

1995 • 544 citations

Polarized sorting in epithelia

1990 • 544 citations

The rate of bulk flow from the endoplasmic reticulum to the cell surface

1987 • 542 citations

The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein.

1986 • 533 citations

The retention signal for soluble proteins of the endoplasmic reticulum

1990 • 531 citations

'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles

1991 • 524 citations

Pre- and post-golgi vacuoles operate in the transport of semliki forest virus membrane glycoproteins to the cell surface

1984 • 523 citations

Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain.

1989 • 513 citations

Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein

1993 • 504 citations

A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

1994 • 501 citations

Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum

1989 • 499 citations

Involvement of GTP-binding “G” proteins in transport through the Golgi stack

1987 • 495 citations

Complexins: Cytosolic proteins that regulate SNAP receptor function

1995 • 494 citations

β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the golgi complex, shows homology to β-adaptin

1991 • 489 citations

Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor.

1982 • 478 citations

VESICLE-MEDIATED PROTEIN SORTING

1992 • 472 citations

Lipid Traffic in Animal Cells

1989 • 468 citations

A new type of coated vesicular carrier that appears not to contain clathrin: Its possible role in protein transport within the Golgi stack

1986 • 462 citations

Caveolae and sorting in the trans-Golgi network of epithelial cells.

1993 • 461 citations

SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER

1993 • 459 citations

Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.

1995 • 455 citations

Pathways to Regulated Exocytosis in Neurons

1990 • 454 citations

A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation

1992 • 450 citations

A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus.

1989 • 443 citations

Compartmental organization of the golgi stack

1985 • 442 citations

Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment.

1988 • 434 citations

Protein sorting in yeast: Mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway

1986 • 429 citations

The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein

1993 • 422 citations

Retrieval of transmembrane proteins to the endoplasmic reticulum.

1993 • 414 citations

GTPases: Multifunctional Molecular Switches Regulating Vesicular Traffic

1994 • 411 citations

Calreticulin

1992 • 402 citations

Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum

1992 • 396 citations

N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.

1994 • 395 citations

Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum

1994 • 392 citations

Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack

1988 • 389 citations

An investigation of the role of transmembrane domains in Golgi protein retention.

1995 • 384 citations

A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin

1991 • 376 citations

Requirement for a GTPase-Activating Protein in Vesicle Budding from the Endoplasmic Reticulum

1993 • 375 citations

The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell

1990 • 372 citations

Transport of Proteins Across the Endoplasmic Reticulum Membrane

1992 • 366 citations

Binding of ARF and β-COP to Golgi Membranes: Possible Regulation by a Trimeric G Protein

1991 • 359 citations

Vesicles and cisternae in the trans golgi apparatus of human fibroblasts are acidic compartments

1985 • 350 citations

Mapping the distribution of Golgi enzymes involved in the construction of complex oligosaccharides

1995 • 350 citations

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

1991 • 347 citations

The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi.

1995 • 341 citations

Characterization of the budding compartment of mouse hepatitis virus: evidence that transport from the RER to the Golgi complex requires only one vesicular transport step

1994 • 339 citations

Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore

1994 • 338 citations

β-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo

1993 • 336 citations

A human homologue of the yeast HDEL receptor

1990 • 336 citations

Binding of coatomer to Golgi membranes requires ADP-ribosylation factor

1993 • 334 citations

Clostridial neurotoxins: new tools for dissecting exocytosis

1994 • 323 citations

A protein of the endoplasmic reticulum involved early in polypeptide translocation

1992 • 322 citations

An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum.

1994 • 315 citations

Distribution of the intermediate elements operating in ER to Golgi transport

1991 • 315 citations

The 25 kDa synaptosomal-associated protein SNAP-25 is the major methionine-rich polypeptide in rapid axonal transport and a major substrate for palmitoylation in adult CNS

1992 • 314 citations

A class of membrane proteins with a C-terminal anchor

1993 • 311 citations

SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex.

1992 • 311 citations

Combined influence of cholesterol and synthetic amphiphillic peptides upon bilayer thickness in model membranes

1992 • 309 citations

Three-dimensional electron microscopy: structure of the Golgi apparatus.

1990 • 307 citations

Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments.

1994 • 304 citations

Targeting of membrane proteins to endosomes and lysosomes

1994 • 304 citations

Stepwise assembly of functionally active transport vesicles

1993 • 298 citations

Sequences within and adjacent to the transmembrane segment of alpha-2,6-sialyltransferase specify Golgi retention.

1991 • 296 citations

The endoplasmic reticulum as a protein-folding compartment

1992 • 296 citations

The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide

1989 • 293 citations

Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd protein

1992 • 291 citations

Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein

1989 • 288 citations

SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

1994 • 288 citations

The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation

1993 • 286 citations

Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane.

1995 • 285 citations

Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles.

1993 • 278 citations

Kin recognition between medial Golgi enzymes in HeLa cells.

1994 • 278 citations

COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast

1995 • 278 citations

SNAP family of NSF attachment proteins includes a brain-specific isoform

1993 • 277 citations

Rab proteins and the road maps for intracellular transport

1993 • 276 citations

A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast.

1988 • 275 citations

Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins.

1995 • 274 citations

Distinct transport vesicles mediate the delivery of plasma membrane proteins to the apical and basolateral domains of MDCK cells.

1990 • 273 citations

Plasma membrane protein sorting in polarized epithelial cells.

1992 • 272 citations

A synaptic vesicle membrane protein is conserved from mammals to Drosophila

1989 • 272 citations

A multisubunit particle implicated in membrane fusion.

1992 • 271 citations

Dissection of a single round of vesicular transport: Sequential intermediates for intercisternal movement in the Golgi stack

1989 • 269 citations

rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin.

1995 • 269 citations

Tyrosine sulfation is a trans-Golgi-specific protein modification.

1987 • 261 citations

ARF: a key regulatory switch in membrane traffic and organelle structure

1994 • 258 citations

Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence.

1993 • 258 citations

The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer

1995 • 253 citations

Identification of an intermediate compartment involved in protein transport from endoplasmic reticulum to Golgi apparatus.

1990 • 252 citations

Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport

1989 • 250 citations

The ERD2 gene determines the specificity of the luminal ER protein retention system

1990 • 243 citations

Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane.

1994 • 237 citations

The membrane spanning domain of beta-1,4-galactosyltransferase specifies trans Golgi localization.

1991 • 237 citations

Topography of glycosylation reactions in the endoplasmic reticulum

1992 • 237 citations

Tetanus and botulism neurotoxins: a new group of zinc proteases

1993 • 233 citations

pH-dependent binding of KDEL to its receptor in vitro.

1993 • 232 citations

TGN38 is maintained in the trans-Golgi network by a tyrosine-containing motif in the cytoplasmic domain.

1993 • 231 citations

HVEM tomography of the trans-Golgi network: structural insights and identification of a lace-like vesicle coat.

1994 • 229 citations

Tubulovesicular processes emerge from trans-Golgi cisternae, extend along microtubules, and interlink adjacent trans-Golgi elements into a reticulum

1990 • 227 citations

The endoplasmic reticulum—Golgi intermediate compartment

1992 • 224 citations

Kin recognition

1993 • 223 citations

Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product.

1988 • 220 citations

The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins.

1993 • 219 citations

Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol

1993 • 218 citations

Signal peptides open protein-conducting channels in E. coli

1992 • 216 citations

Sequential intermediates in the pathway of intercompartmental transport in a cell-free system

1984 • 211 citations

Endocytosis and signals for internalization

1991 • 209 citations

Fatty acyl-coenzyme a is required for budding of transport vesicles from Golgi cisternae

1989 • 204 citations

Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins

1991 • 199 citations

SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer

1992 • 198 citations

Recycling of proteins from the Golgi compartment to the ER in yeast.

1990 • 196 citations

Recycling of proteins between the endoplasmic reticulum and Golgi complex

1991 • 194 citations

Degradation of proteins within the endoplasmic reticulum

1991 • 191 citations

A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules

1991 • 188 citations

Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus.

1991 • 183 citations

Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation

1993 • 183 citations

Isolation of a matrix that binds medial Golgi enzymes

1994 • 181 citations

Domain structure of an N-ethylmaleimide-sensitive fusion protein involved in vesicular transport.

1993 • 178 citations

BET1, BOS1, and SEC22 Are Members of a Group of Interacting Yeast Genes Required for Transport from the Endoplasmic Reticulum to the Golgi Complex

1990 • 176 citations

Chemical and immunological characterization of the 21-kDa ADP-ribosylation factor of adenylate cyclase.

1988 • 175 citations

Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins

1993 • 174 citations

The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.

1994 • 169 citations

Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains.

1994 • 162 citations

ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus.

1990 • 160 citations

Biogenesis of constitutive secretory vesicles, secretory granules and synaptic vesicles

1993 • 159 citations

The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein.

1992 • 159 citations

Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus

1995 • 157 citations

Molecular cloning, characterization, subcellular localization and dynamics of p23, the mammalian KDEL receptor.

1993 • 154 citations

Retention and retrieval: both mechanisms cooperate to maintain calreticulin in the endoplasmic reticulum

1994 • 154 citations

Oligomerization of a membrane protein correlates with its retention in the Golgi complex

1993 • 154 citations

Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein

1989 • 154 citations

Syntaxin 5 regulates endoplasmic reticulum to Golgi transport.

1994 • 153 citations

Annexin XIIIb: a novel epithelial specific annexin is implicated in vesicular traffic to the apical plasma membrane.

1995 • 150 citations

Membrane protein retention in the yeast Golgi apparatus: dipeptidyl aminopeptidase A is retained by a cytoplasmic signal containing aromatic residues.

1993 • 148 citations

A brefeldin A-like phenotype is induced by the overexpression of a human ERD-2-like protein, ELP-1

1992 • 148 citations

Purification of three related peripheral membrane proteins needed for vesicular transport.

1990 • 147 citations

Selective and immediate effects of clathrin heavy chain mutations on Golgi membrane protein retention in Saccharomyces cerevisiae.

1992 • 147 citations

En bloc incorporation of coatomer subunits during the assembly of COP- coated vesicles [published erratum appears in J Cell Biol 1994 Jul;126(2):589]

1994 • 146 citations

Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport.

1993 • 144 citations

TGN38/41 recycles between the cell surface and the TGN: brefeldin A affects its rate of return to the TGN.

1993 • 143 citations

Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER.

1991 • 143 citations

Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.

1993 • 142 citations

Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic.

1994 • 137 citations

Bos1p, an integral membrane protein of the endoplasmic reticulum to Golgi transport vesicles, is required for their fusion competence

1993 • 137 citations

The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network.

1994 • 134 citations

Beta-COP is essential for transport of protein from the endoplasmic reticulum to the Golgi in vitro

1993 • 133 citations

Vps1p, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiae.

1993 • 132 citations

The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack.

1995 • 129 citations

Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro.

1989 • 128 citations

Characterization of new mutants in the early part of the yeast secretory pathway isolated by a [3H]mannose suicide selection.

1987 • 127 citations

Pathways of protein sorting and membrane traffic between the rough endoplasmic reticulum and the Golgi complex

1992 • 127 citations

Immunocytochemical localization of β-COP to the ER-Golgi boundary and the TGN

1995 • 127 citations

Sec23p and a novel 105-kDa protein function as a multimeric complex to promote vesicle budding and protein transport from the endoplasmic reticulum.

1992 • 126 citations

Transport and sorting of membrane lipids

1993 • 123 citations

Assembly of Bcl-2 into microsomal and outer mitochondrial membranes

1994 • 123 citations

The SXYQRL sequence in the cytoplasmic domain of TGN38 plays a major role in trans-Golgi network localization.

1993 • 121 citations

Signals and salvage sequences

1987 • 121 citations

Two distinct populations of ARF bound to Golgi membranes.

1993 • 118 citations

beta′-COP, a novel subunit of coatomer.

1993 • 114 citations

About turn for the COPs?

1994 • 114 citations

Lipid traffic in eukaryotic cells: mechanisms for intracelluar transport and organelle-specific enrichment of lipids

1990 • 114 citations

Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA

1987 • 110 citations

Targeting and retention of Golgi membrane proteins

1993 • 110 citations

Differential inhibition of multiple vesicular transport steps between the endoplasmic reticulum and trans Golgi network.

1993 • 108 citations

Golgi retention signals: do membranes hold the key?

1991 • 106 citations

Molecular recognition and targeting of lysosomal proteins

1991 • 105 citations

Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum.

1995 • 105 citations

BET1, BOS1, and SEC22 are members of a group of interacting yeast genes required for transport from the endoplasmic reticulum to the Golgi complex.

1990 • 104 citations

ADP-ribosylation factor and coatomer couple fusion to vesicle budding

1994 • 104 citations

Beta 1,4-galactosyltransferase: a short NH2-terminal fragment that includes the cytoplasmic and transmembrane domain is sufficient for Golgi retention.

1992 • 100 citations

Trans‐Golgi network (TGN) of different cell types: Three‐dimensional structural characteristics and variability

1995 • 96 citations

The transmembrane and flanking sequences of beta 1,2-N-acetylglucosaminyltransferase I specify medial-Golgi localization.

1992 • 92 citations

Protein translocation across the endoplasmic reticulum: A tunnel with toll booths at entry and exit

1993 • 91 citations

A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins.

1993 • 90 citations

ADP-ribosylation Factor-directed GTPase-activating Protein

1995 • 87 citations

Multiple N-ethylmaleimide-sensitive components are required for endosomal vesicle fusion.

1994 • 85 citations

Sequence of a second human KDEL receptor

1992 • 85 citations

Bos1p, a membrane protein required for ER to Golgi transport in yeast, co-purifies with the carrier vesicles and with Bet1p and the ER membrane.

1992 • 79 citations

The glycoprotein that is transported between successive compartments of the golgi in a cell-free system resides in stacks of cisternae

1984 • 76 citations

zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly.

1993 • 75 citations

Control of protein traffic between distinct plasma membrane domains. Requirement for a novel 108,000 protein in the fusion of transcytotic vesicles with the apical plasma membrane.

1993 • 71 citations

An endoplasmic reticulum retention signal in the CD3ɛ chain of the T-cell receptor

1992 • 67 citations

Medial-Golgi retention of N-acetylglucosaminyltransferase I. Contribution from all domains of the enzyme.

1994 • 62 citations

γ‐COP, a coat subunit of non‐clathrin‐coated vesicles with homology to Sec21p

1992 • 59 citations

TGN38/41: a molecule on the move

1993 • 56 citations

Anterograde transport through the Golgi complex: do Golgi tubules hold the key?

1995 • 55 citations

NADH‐cytochrome b₅ reductase and cytochrome b₅ isoforms as models for the study of post‐translational targeting to the endoplasmic reticulum

1993 • 55 citations

Eukaryotic membrane traffic: retrieval and retention mechanisms to achieve organelle residence

1993 • 51 citations

SNAREs and targeted membrane fusion

1995 • 51 citations

Polarity signals

1991 • 50 citations

Mitosis and inhibition of intracellular transport stimulate palmitoylation of a 62-kD protein.

1992 • 50 citations

Dynamic retention of TGN membrane proteins in Saccharomyces cerevisiae

1993 • 48 citations

Intracellular lipid heterogeneity caused by topology of synthesis and specificity in transport. Example: sphingolipids

1995 • 44 citations

The neuronal endomembrane system. II. The multiple forms of the Golgi apparatus cis element

1985 • 42 citations

COPII: a membrane coat that forms endoplasmic reticulum‐derived vesicles

1995 • 41 citations

Disruption of endoplasmic reticulum to Golgi transport leads to the accumulation of large aggregates containing beta-COP in pancreatic acinar cells.

1993 • 40 citations

ADP ribosylation factor and a 14-kD polypeptide are associated with heparan sulfate-carrying post-trans-Golgi network secretory vesicles in rat hepatocytes.

1994 • 37 citations

Springs and hinges: dynamic coiled coils and discontinuities

1994 • 36 citations

The endoplasmic reticulum retention signal of the E3/19K protein of adenovirus-2 is microtubule binding

1991 • 35 citations

Membrane traffic in animal cells

1984 • 33 citations

Vesicle budding: insights from cell-free assays

1991 • 29 citations

SEC22 and SLY2 are identical.

1992 • 29 citations

Protein translocation across the endoplasmic reticulum

1994 • 29 citations

Protein palmitoylation in membrane trafficking

1995 • 22 citations

Yeast coatomer contains a subunit homologous to mammalian β'‐COP

1993 • 21 citations

COP‐coated vesicles in intracellular protein transport

1995 • 20 citations

Protein targeting to dense‐core secretory granules

1993 • 18 citations

Redrawing compartmental boundaries in the exocytic pathway

1995 • 16 citations

Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells

1989 • 15 citations

Chapter 5 Preparation of Semiintact Chinese Hamster Ovary Cells for Reconstitution of Endoplasmic Reticulum-to-Golgi Transport in a Cell-Free System

1989 • 4 citations

Truncated ceramide analogs as probes for sphingolipid biosynthesis and transport.

1993 • 3 citations