Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins.

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Protein folding in the cell

1992 • 4,138 citations

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution

1981 • 2,490 citations

Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.

1994 • 815 citations

How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum.

1994 • 617 citations

Association of folding intermediates of glycoproteins with calnexin during protein maturation

1993 • 558 citations

Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum

1995 • 544 citations

Calnexin: a membrane-bound chaperone of the endoplasmic reticulum

1994 • 533 citations

Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus.

1994 • 447 citations

The Molecular Chaperone Calnexin Binds Glc1Man9GlcNAc2 Oligosaccharide as an Initial Step in Recognizing Unfolded Glycoproteins

1995 • 417 citations

Calreticulin

1992 • 402 citations

Glycosidase inhibitors: inhibitors of N‐linked oligosaccharide processing

1991 • 373 citations

Inhibition of nuclear hormone receptor activity by calreticulin

1994 • 372 citations

Perturbation of cellular calcium induces secretion of luminal ER proteins

1989 • 370 citations

Regulation of MHC Class I Transport by the Molecular Chaperone, Calnexin (p88, IP90)

1994 • 351 citations

Expression of calreticulin in Escherichia coli and identification of its Ca2+ binding domains.

1991 • 350 citations

Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change.

1985 • 341 citations

Folding of influenza hemagglutinin in the endoplasmic reticulum.

1991 • 318 citations

Folding of VSV G Protein: Sequential Interaction with BiP and Calnexin

1994 • 316 citations

Recognition of the oligosaccharide and protein moieties of glycoproteins by the UDP-Glc:glycoprotein glucosyltransferase

1992 • 313 citations

The involvement of calcium in transport of secretory proteins from the endoplasmic reticulum

1990 • 310 citations

The endoplasmic reticulum as a protein-folding compartment

1992 • 296 citations

Studies on the Glycosidases in Jack Bean Meal

1967 • 260 citations

Cotranslational folding and calnexin binding during glycoprotein synthesis.

1995 • 248 citations

Retention of Unassembled Components of Integral Membrane Proteins by Calnexin

1994 • 243 citations

Identification of a set of calcium-binding proteins in reticuloplasm, the luminal content of the endoplasmic reticulum

1988 • 238 citations

Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum.

1991 • 236 citations

Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin)

1993 • 203 citations

Regulation of expression and intracellular distribution of calreticulin, a major calcium binding protein of nonmuscle cells

1991 • 162 citations

Glucosylation of glycoproteins by mammalian, plant, fungal, and trypanosomatid protozoa microsomal membranes

1989 • 155 citations

Retention and retrieval: both mechanisms cooperate to maintain calreticulin in the endoplasmic reticulum

1994 • 154 citations

Quality control in the endoplasmic reticulum: folding and misfolding of vesicular stomatitis virus G protein in cells and in vitro.

1990 • 153 citations

Cell attachment to extracellular matrix substrates is inhibited upon downregulation of expression of calreticulin, an intracellular integrin α-subunit-binding protein

1994 • 148 citations

The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes.

1993 • 137 citations

Calnexin Recognizes Carbohydrate and Protein Determinants of Class I Major Histocompatibility Complex Molecules

1995 • 129 citations

Persistence of glucose residues on core oligosaccharides prevents association of TCR alpha and TCR beta proteins with calnexin and results specifically in accelerated degradation of nascent TCR alpha proteins within the endoplasmic reticulum.

1994 • 117 citations

An efficient method for introducing macromolecules into living cells.

1985 • 114 citations

Posttranslational folding of vesicular stomatitis virus G protein in the ER: involvement of noncovalent and covalent complexes.

1993 • 113 citations

Structure and homology of human C1q receptor (collectin receptor).

1993 • 110 citations

A lectin-resistant mouse lymphoma cell line is deficient in glucosidase II, a glycoprotein-processing enzyme.

1982 • 110 citations

Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.

1989 • 106 citations

The 5'-flanking region of the human calreticulin gene shares homology with the human GRP78, GRP94, and protein disulfide isomerase promoters.

1992 • 99 citations

Intracellular transport of soluble and membrane-bound glycoproteins: folding, assembly and secretion of anchor-free influenza hemagglutinin.

1990 • 97 citations

Folding and oligomerization of influenza hemagglutinin in the ER and the intermediate compartment.

1995 • 95 citations

Molecular Requirements for the Interaction of Class II Major Histocompatibility Complex Molecules and Invariant Chain with Calnexin

1995 • 95 citations

Different sorting of Lys-Asp-Glu-Leu proteins in rat liver.

1992 • 89 citations

Polypeptide Interactions with Molecular Chaperones and their Relationship to In Vivo Protein Folding

1994 • 83 citations

Long-Term sensitization training in Aplysia leads to an increase in calreticulin, a major presynaptic calcium-binding protein

1992 • 80 citations

Reconstitution of transport of vesicular stomatitis virus G protein from the endoplasmic reticulum to the Golgi complex using a cell-free system.

1987 • 77 citations

Presence of Inositol 1,4,5-Trisphosphate Receptor, Calreticulin, and Calsequestrin in Eggs of Sea Urchins and Xenopus laevis

1994 • 74 citations

Post-translational folding of influenza hemagglutinin in isolated endoplasmic reticulum-derived microsomes.

1993 • 71 citations

Selective retention of monoglucosylated high mannose oligosaccharides by a class of mutant vesicular stomatitis virus G proteins.

1989 • 59 citations

A novel glycosylation phenotype expressed by Lec23, a Chinese hamster ovary mutant deficient in alpha-glucosidase I.

1991 • 53 citations

Heat shock-induced prompt glycosylation. Identification of P-SG67 as calreticulin.

1994 • 52 citations

Sequence similarity of calreticulin with a Ca2+-binding protein that co-purifies with an Ins(1,4,5)P3-sensitive Ca2+ store in HL-60 cells

1990 • 52 citations

Castanospermine inhibits the function of the low-density lipoprotein receptor

1989 • 37 citations

Calreticulin — a stress protein induced in the renal epithelial cell line NBL-1 by amino acid deprivation

1994 • 26 citations

A Single Purification Procedure for the Major Resident Proteins of the ER Lumen: Endoplasmin, BiP, Calreticulin and Protein Disulfide Isomerase

1994 • 21 citations