Plasma membrane protein sorting in polarized epithelial cells.

Molecular Biology of the Cell

2017 • 5,885 citations

Morphogenesis of the Polarized Epithelial Cell Phenotype

1989 • 1,087 citations

Constitutive and Regulated Secretion of Proteins

1987 • 1,021 citations

Cell Surface Polarity in Epithelia

1985 • 880 citations

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 • 832 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Polarized sorting in epithelia

1990 • 544 citations

The rate of bulk flow from the endoplasmic reticulum to the cell surface

1987 • 542 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Asymmetric budding of viruses in epithelial monlayers: a model system for study of epithelial polarity.

1978 • 492 citations

Lipid Traffic in Animal Cells

1989 • 468 citations

Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomes

1991 • 378 citations

Mechanism of Membrane Anchoring Affects Polarized Expression of Two Proteins in MDCK Cells

1989 • 377 citations

Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA

1986 • 313 citations

Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant

1991 • 304 citations

An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor

1991 • 298 citations

Distinct transport vesicles mediate the delivery of plasma membrane proteins to the apical and basolateral domains of MDCK cells.

1990 • 273 citations

Phosphorylation of the Polymeric Immunoglobulin Receptor Required for Its Efficient Transcytosis

1990 • 267 citations

Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2)

1990 • 262 citations

A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.

1991 • 257 citations

Selective inhibition of transcytosis by brefeldin A in MDCK cells

1991 • 254 citations

Development of cell polarity in budding yeast

1991 • 252 citations

Mechanisms Regulating Pattern Formation in the Amphibian Egg and Early Embryo

1980 • 250 citations

CLATHRIN AND ASSOCIATED ASSEMBLY AND DISASSEMBLY PROTEINS

1990 • 234 citations

Glycophospholipid membrane anchoring provides clues to the mechanism of protein sorting in polarized epithelial cells

1990 • 233 citations

Polarized sorting of glypiated proteins in hippocampal neurons

1991 • 233 citations

Viral glycoproteins destined for apical or basolateral plasma membrane domains traverse the same Golgi apparatus during their intracellular transport in doubly infected Madin-Darby canine kidney cells.

1984 • 228 citations

Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line.

1990 • 228 citations

Molecular Cloning of YPT1/SEC4-Related cDNAs from an Epithelial Cell Line

1990 • 210 citations

Endocytosis and signals for internalization

1991 • 209 citations

Differential extractability of influenza virus hemagglutinin during intracellular transport in polarized epithelial cells and nonpolar fibroblasts.

1989 • 204 citations

Deletion of the cytoplasmic domain of the polymeric immunoglobulin receptor prevents basolateral localization and endocytosis

1986 • 202 citations

Constitutive apical secretion of an 80-kD sulfated glycoprotein complex in the polarized epithelial Madin-Darby canine kidney cell line.

1987 • 201 citations

Small GTP-binding proteins and their role in transport

1991 • 164 citations

Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

1989 • 159 citations

Transcytosis

1985 • 154 citations

An internal deletion in the cytoplasmic tail reverses the apical localization of human NGF receptor in transfected MDCK cells.

1991 • 153 citations

Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells.

1990 • 144 citations

Expression of macrophage-lymphocyte Fc receptors in Madin-Darby canine kidney cells: polarity and transcytosis differ for isoforms with or without coated pit localization domains.

1989 • 143 citations

Preferred apical distribution of glycosyl-phosphatidylinositol (GPI) anchored proteins: A highly conserved feature of the polarized epithelial cell phenotype

1990 • 143 citations

Plasma membrane protein sorting in epithelial cells: Do secretory pathways hold the key?

1988 • 121 citations

Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice.

1990 • 108 citations

Transcytosis in MDCK cells: identification of glycoproteins transported bidirectionally between both plasma membrane domains.

1990 • 96 citations

Transplanted LDL and mannose-6-phosphate receptor internalization signals promote high-efficiency endocytosis of the transferrin receptor.

1991 • 93 citations

Protein traffic between distinct plasma membrane domains: Isolation and characterization of vesicular carriers involved in transcytosis

1991 • 89 citations

Transport of influenza HA from the trans-Golgi network to the apical surface of MDCK cells permeabilized in their basolateral plasma membranes: energy dependence and involvement of GTP-binding proteins.

1990 • 88 citations

Exocytic transport vesicles generated in vitro from the trans-Golgi network carry secretory and plasma membrane proteins.

1990 • 85 citations

An anchor-minus form of the polymeric immunoglobulin receptor is secreted predominantly apically in Madin-Darby canine kidney cells.

1987 • 76 citations

Generation and maintenance of epithelial cell polarity

1990 • 76 citations

Selective internalization of the apical plasma membrane and rapid redistribution of lysosomal enzymes and mannose 6-phosphate receptors during osteoclast inactivation by calcitonin

1990 • 74 citations

Apical and basolateral transferrin receptors in polarized BeWo cells recycle through separate endosomes.

1991 • 71 citations

Inhibition by brefeldin A of protein secretion from the apical cell surface of Madin-Darby canine kidney cells.

1991 • 66 citations

Involvement of β-COP in membrane traffic through the Golgi complex

1991 • 64 citations

A hepatocyte-specific basolateral membrane protein is targeted to the same domain when expressed in Madin-Darby canine kidney cells

1989 • 59 citations

Aminopeptidase N is directly sorted to the apical domain in MDCK cells.

1990 • 59 citations

Apical cell surface expression of rat dipeptidyl peptidase IV in transfected Madin-Darby canine kidney cells

1991 • 52 citations

Cell Surface Polarity in Epithelia

1985 • 52 citations

Polarity signals

1991 • 50 citations

Surface distribution of the mannose 6-phosphate receptors in epithelial Madin-Darby canine kidney cells.

1990 • 47 citations

Molecular and cellular mechanisms involved in transepithelial transport

1991 • 41 citations

Global properties of the Xenopus blastula are mediated by a high-resistance epithelial seal

1986 • 39 citations

Sorting signals

1989 • 34 citations

Sorting of plasma membrane proteins in epithelial cells

1991 • 32 citations

Involvement of both vectorial and transcytotic pathways in the preferential apical cell surface localization of rat dipeptidyl peptidase IV in transfected LLC-PK1 cells.

1991 • 22 citations

Low density lipoprotein receptors on epithelial cell (Madin-Darby canine kidney) monolayers. Asymmetric distribution correlates with functional difference

1991 • 18 citations

Endocytosis and signals for internalization

1991 • 8 citations