Cell Surface Polarity in Epithelia

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

1963 • 3,559 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

Intermediate filaments as mechanical integrators of cellular space

1980 • 1,973 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

Role of collagenous matrices in the adhesion and growth of cells.

1981 • 1,375 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

Methods for growth of cultured cells in serum-free medium

1980 • 1,013 citations

The Golgi apparatus (complex)-(1954-1981)-from artifact to center stage.

1981 • 990 citations

Culture of hormone-dependent functional epithelial cells from rat thyroids.

1980 • 959 citations

Die Molekularbiologie der Tumorviren

1977 • 951 citations

Transfer of Proteins Across Membranes

1981 • 894 citations

Mechanisms for the incorporation of proteins in membranes and organelles.

1982 • 875 citations

Polarized monolayers formed by epithelial cells on a permeable and translucent support

1978 • 869 citations

Cellular Adhesiveness and Extracellular Substrata

1978 • 829 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Route of Passive Ion Permeation in Epithelia

1972 • 762 citations

Structure of the junction between communicating cells

1980 • 697 citations

VARIATIONS IN TIGHT AND GAP JUNCTIONS IN MAMMALIAN TISSUES

1972 • 674 citations

Membrane fusion proteins of enveloped animal viruses

1983 • 670 citations

Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells.

1982 • 642 citations

A FINE STRUCTURAL ANALYSIS OF INTERCELLULAR JUNCTIONS IN THE MOUSE LIVER

1970 • 626 citations

Receptor-mediated endocytosis of transferrin in K562 cells.

1983 • 576 citations

Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula Occludens

1978 • 569 citations

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen

1984 • 566 citations

Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition.

1984 • 545 citations

The distribution of phosphatase in normal organs and tissues

1941 • 511 citations

Reduced temperature prevents transfer of a membrane glycoprotein to the cell surface but does not prevent terminal glycosylation

1983 • 504 citations

Transepithelial transport in cell culture.

1976 • 499 citations

Antibody to prekeratin

1978 • 496 citations

Asymmetric budding of viruses in epithelial monlayers: a model system for study of epithelial polarity.

1978 • 492 citations

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation.

1984 • 447 citations

The Golgi Apparatus: Two Organelles in Tandem

1981 • 438 citations

Topology of microvillar membrance hydrolases of kidney and intestine.

1982 • 437 citations

Mammalian plasma membranes

1975 • 425 citations

Exit of newly synthesized membrane proteins from the trans cisterna of the Golgi complex to the plasma membrane.

1985 • 415 citations

Nucleotide sequences of the mRNA's encoding the vesicular stomatitis virus G and M proteins determined from cDNA clones containing the complete coding regions

1981 • 404 citations

Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver.

1984 • 393 citations

Immunoelectron microscope studies of membrane-microfilament interactions: distributions of alpha-actinin, tropomyosin, and vinculin in intestinal epithelial brush border and chicken gizzard smooth muscle cells.

1981 • 386 citations

Experimental modulation of occluding junctions in a cultured transporting epithelium.

1980 • 375 citations

The preimplantation mammalian embryo: Characterization of intercellular junctions and their appearance during development

1975 • 359 citations

Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver

1984 • 359 citations

Adsorptive endocytosis of Semliki Forest virus

1980 • 354 citations

Cell shape and membrane changes in the eight-cell mouse embryo: Prerequisites for morphogenesis of the blastocyst

1975 • 340 citations

Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.

1984 • 336 citations

The Role of extracellular matrix in development

1984 • 334 citations

Formation of cytoskeletal elements during mouse embryogenesis. IV. Ultrastructure of primary mesenchymal cells and their cell-cell interactions.

1983 • 320 citations

Cell surface interaction induces polarization of mouse 8-cell blastomeres at compaction

1980 • 314 citations

Functional polarity of the rat hepatocyte surface membrane. Isolation and characterization of plasma-membrane subfractions from the blood-sinusoidal, bile-Canalicular and contiguous surfaces of the hepatocyte

1975 • 308 citations

Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures.

1980 • 306 citations

THE CYTOCHEMICAL APPLICATION OF NEW POTENT INHIBITORS OF ALKALINE PHOSPHATASES

1973 • 300 citations

Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes.

1984 • 295 citations

Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA

1979 • 292 citations

The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae

1984 • 291 citations

Evidence for the lipidic nature of tight junction strands

1982 • 277 citations

Cell-free synthesis and membrane insertion of mouse H-2Dd histocompatibility antigen and β2-microglobulin

1979 • 274 citations

Polarized distribution of viral envelope proteins in the plasma membrane of infected epithelial cells

1980 • 273 citations

Villin: The major microfilament-associated protein of the intestinal microvillus

1979 • 270 citations

Identification of two strains of MDCK cells which resemble separate nephron tubule segments

1981 • 269 citations

The use of isolated membrane vesicles to study epithelial transport processes

1980 • 262 citations

Formation of Cytoskeletal Elements During Mouse Embryogenesis

1982 • 259 citations

Sorting of an apical plasma membrane glycoprotein occurs before it reaches the cell surface in cultured epithelial cells.

1984 • 247 citations

Density of newly synthesized plasma membrane proteins in intracellular membranes II. Biochemical studies.

1984 • 246 citations

Evidence for the sorting of endocytic vesicle contents during the receptor-mediated transport of IgG across the newborn rat intestine.

1981 • 244 citations

Lipid dynamics and lipid-protein interactions in rat enterocyte basolateral and microvillus membranes

1980 • 243 citations

Biochemical and immunological characterization of desmoplakins I and II, the major polypeptides of the desmosomal plaque

1983 • 243 citations

Vesicular stomatitis virus infects and matures only through the basolateral surface of the polarized epithelial cell line, MDCK

1984 • 236 citations

The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix.

1984 • 236 citations

A 135-kd membrane protein of intercellular adherens junctions.

1984 • 235 citations

Viral glycoproteins destined for apical or basolateral plasma membrane domains traverse the same Golgi apparatus during their intracellular transport in doubly infected Madin-Darby canine kidney cells.

1984 • 228 citations

Isolation and characterization of gap junctions from rat liver.

1979 • 228 citations

Receptor-mediated endocytosis: coated pits, receptosomes and the Golgi

1983 • 225 citations

Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study.

1979 • 223 citations

Development of cell surface polarity in the epithelial Madin-Darby canine kidney (MDCK) cell line.

1984 • 220 citations

Primary structure of the rat liver asialoglycoprotein receptor. Structural evidence for multiple polypeptide species.

1984 • 219 citations

On tight-junction structure

1982 • 218 citations

Biosynthesis and glycosylation of the insulin receptor. Evidence for a single polypeptide precursor of the two major subunits.

1983 • 216 citations

Structure of the neuraminidase gene in human influenza virus A/PR/8/34

1981 • 216 citations

Calcium ion transport across plasma membranes isolated from rat kidney cortex

1979 • 212 citations

Immunoferritin determination of the distribution of (Na+ + K+) ATPase over the plasma membranes of renal convoluted tubules. I. Distal segment.

1976 • 208 citations

Intracellular transport of cholesterol to the plasma membrane.

1982 • 203 citations

Rat liver canalicular membrane vesicles. Isolation and topological characterization.

1983 • 202 citations

Redistribution of surface macromolecules in dissociated epithelial cells.

1976 • 202 citations

Transmembrane assembly of membrane and secretory glycoproteins

1981 • 188 citations

Glycosphingolipids of Plasma Membranes of Cultured Cells and an Enveloped Virus (SV5) Grown in These Cells

1970 • 186 citations

A biochemical dissection of the functional polarity of the plasma membrane of the hepatocyte

1980 • 184 citations

Sequence relationships among the hemagglutinin genes of 12 subtypes of influenza A virus.

1981 • 183 citations

Location of the Spike Glycoproteins in the Semliki Forest Virus Membrane

1974 • 180 citations

LOCALIZATION OF SODIUM PUMPS IN THE CHOROID PLEXUS EPITHELIUM

1973 • 178 citations

Hormone-Sensitive Adenyl Cyclase: Cytochemical Localization in Rat Liver

1970 • 174 citations

A cell line derived from normal dog kidney (MDCK) exhibiting qualities of papillary adenocarcinoma and of renal tubular epithelium

1970 • 174 citations

Microdomains of distinctive glycoprotein composition in the kidney proximal tubule brush border.

1984 • 174 citations

Occluding junctions in cultured epithelial monolayers

1981 • 173 citations

Bile Secretory Apparatus: Evidence for a Vesicular Transport Mechanism for Proteins in the Rat, Using Horseradish Peroxidase and [125I]Insulin

1980 • 172 citations

Lipid components of two different regions of an intestinal epithelial cell membrane of mouse

1974 • 167 citations

Transport properties of toad kidney epithelia in culture

1981 • 164 citations

Distribution of antibody- and lectin-binding sites on dissociated blastomeres from mouse morulae: evidence for polarization at compaction

1980 • 162 citations

Attachment of vimentin filaments to desmosomal plaques in human meningiomal cells and arachnoidal tissue.

1984 • 161 citations

An enzymatic assay reveals that proteins destined for the apical or basolateral domains of an epithelial cell line share the same late Golgi compartments.

1985 • 154 citations

Cytochemical localization of Na+, K+-ATPase in the rat hepatocyte.

1978 • 154 citations

Hemidesmosome formation in vitro.

1983 • 154 citations

Lipid composition of the isolated rat intestinal microvillus membrane

1968 • 150 citations

A protein homologous to the 27,000 dalton liver gap junction protein is present in a wide variety of species and tissues

1984 • 150 citations

Viruses budding from either the apical or the basolateral plasma membrane domain of MDCK cells have unique phospholipid compositions.

1982 • 150 citations

Biochemical properties and immunochemical-genetic relationships of mouse H-2 alloantigens

1974 • 143 citations

Growth Factors and the Extracellular Matrix

1980 • 142 citations

Characterization of an integral membrane glycoprotein associated with the microfilaments of pig intestinal microvilli.

1983 • 136 citations

Polarized delivery of viral glycoproteins to the apical and basolateral plasma membranes of Madin-Darby canine kidney cells infected with temperature-sensitive viruses.

1985 • 136 citations

Influenza virus hemagglutinin expression is polarized in cells infected with recombinant SV40 viruses carrying cloned hemagglutinin DNA

1983 • 132 citations

Spatial Distribution of Proteins Specific for Desmosomes and Adhaerens Junctions in Epithelial Cells Demonstrated by Double Immunofluorescence Microscopy

1982 • 131 citations

Presence of a sodium-potassium chloride cotransport system in the rectal gland ofSqualus acanthias

1983 • 130 citations

Studies on the development and maintenance of epithelial cell surface polarity with monoclonal antibodies.

1984 • 127 citations

Nucleotide sequence of a cDNA clone encoding the entire glycoprotein from the New Jersey serotype of vesicular stomatitis virus

1983 • 126 citations

Complete amino acid sequence of a membrane receptor for glycoproteins. Sequence of the chicken hepatic lectin.

1981 • 125 citations

Plasma membrane lipids and parainfluenza virus assembly

1970 • 124 citations

Functionally Differentiated Cell Lines

1982 • 123 citations

Preparation and characterization of the lateral and basal plasma membranes of the rat intestinal epithelial cell

1972 • 123 citations

Intracellular transport of influenza virus hemagglutinin to the apical surface of Madin-Darby canine kidney cells.

1984 • 121 citations

The Pseudotypic Paradox

1982 • 116 citations

Toad urinary bladder epithelial cells in culture: maintenance of epithelial structure, sodium transport, and response to hormones.

1979 • 115 citations

Transcytosis in thyroid follicle cells.

1983 • 114 citations

Ion transport in ‘tight’ epithelial monolayers of MDCK cells

1981 • 113 citations

Simultaneous isolation of brush border and basolateral membrane from rabbit enterocytes. Presence of brush border hydrolases in the basolateral membrane of rabbit enterocytes

1980 • 112 citations

A domain-specific marker for the hepatocyte plasma membrane: localization of leucine aminopeptidase to the bile canalicular domain.

1983 • 111 citations

Glycosylation does not determine segregation of viral envelope proteins in the plasma membrane of epithelial cells.

1981 • 104 citations

Immunocytochemical localization of opsin in the cell membrane of developing rat retinal photoreceptors.

1984 • 103 citations

Effect of amiloride on the apical cell membrane cation channels of a sodium-absorbing, potassium-secreting renal epithelium

1979 • 99 citations

Transport of epidermal growth factor by rat liver: evidence for a nonlysosomal pathway.

1984 • 96 citations

Interaction between cell sodium and the amiloride-sensitive sodium entry step in rabbit colon

1978 • 96 citations

Assembly of Enveloped Rna Viruses

1984 • 95 citations

Chloride transport in the thick ascending limb of Henle's loop: potassium dependence and stoichiometry of the NaCl cotransport system in plasma membrane vesicles

1983 • 95 citations

Extracellular calcium and the organization of tight junctions in pancreatic acinar cells

1976 • 95 citations

Structural integrity of hepatocyte tight junctions.

1983 • 95 citations

Localization of cytoskeletal proteins in preimplantation mouse embryos

1980 • 95 citations

Synthesis of membrane glycoproteins in rat small-intestinal villus cells. Effect of colchicine on the redistribution of <scp>l</scp>-[1,5,6-3H]fucose-labelled membrane glycoproteins among Golgi, lateral basal and microvillus membranes

1979 • 93 citations

The Confined Function Model of the Golgi Complex: Center for Ordered Processing of Biosynthetic Products of the Rough Endoplasmic Reticulum

1983 • 89 citations

Influenza Virus Effects on Cell Membrane Proteins

1970 • 86 citations

Direct evidence for the transmembrane orientation of the hepatic glycoprotein receptors.

1984 • 84 citations

Endocytic pathways at the lateral and basal cell surfaces of exocrine acinar cells.

1982 • 84 citations

(Na+,K+)-cotransport in the Madin-Darby canine kidney cell line. Kinetic characterization of the interaction between Na+ and K+.

1982 • 83 citations

Biosynthesis of intestinal microvillar proteins. Pulse-chase labelling studies on aminopeptidase N and sucrase-isomaltase

1982 • 82 citations

Synthesis and Assembly of Membrane and Organelle Proteins

1981 • 81 citations

Localization of sodium pump sites in cat salivary glands.

1977 • 80 citations

Factors affecting the differentiation of epithelial transport and responsiveness to hormones.

1984 • 78 citations

cDNA clone coding for part of a mouse H-2d major histocompatibility antigen.

1981 • 75 citations

Mechanism of formation of pseudotypes between vesicular stomatitis virus and murine leukemia virus

1977 • 75 citations

A neutral endopeptidase in the microvillar membrane of pig intestine. Partial purification and properties

1980 • 75 citations

Structure of C-terminal half of two H–2 antigens from cloned mRNA

1981 • 74 citations

Amiloride and the sodium channel

1974 • 72 citations

Current Concepts of Liver Structure as Related to Function

1977 • 72 citations

Localization of sodium pump sites in frog urinary bladder

1975 • 71 citations

Transcytosis of the G protein of vesicular stomatitis virus after implantation into the apical plasma membrane of Madin-Darby canine kidney cells. I. Involvement of endosomes and lysosomes.

1984 • 65 citations

Insulin Binding and Degradation by Luminal and Basolateral Tubular Membranes from Rabbit Kidney

1982 • 64 citations

Membrane biogenesis in the sprouting neuron. I. Selective transfer of newly synthesized phospholipid into the growing neurite.

1983 • 64 citations

Analysis of the pinocytic process in rat kidney II. Biochemical composition of pinocytic vesicles compared to brush border microvilli, lysosomes and basolateral plasma membranes

1976 • 63 citations

The Basal Lamina in Epithelial-Mesenchymal Morphogenetic Interactions

1977 • 63 citations

The effects of calcium deficiency on the formation of the zonula occludens and blastocoel in the mouse embryo

1979 • 62 citations

The accumulation of proteins in the nucleus

1985 • 58 citations

Viral Membranes: Model Systems for Studying Biological Membrane

1979 • 57 citations

Lectin-resistant mutants of polarized epithelial cells.

1982 • 56 citations

Pathways of Endocytosis in Thyroid Follicle Cells

1984 • 52 citations

Isolation of the non-glycosylated proteins of desmosomes and immunolocalization of a third plaque protein: desmoplakin III.

1985 • 52 citations

Transport of proteins from blood to bile

1981 • 51 citations

Biosynthesis of intestinal microvillar proteins. Role of the Golgi complex and microtubules

1983 • 50 citations

ANALYSIS OF THE PINOCYTIC PROCESS IN RAT KIDNEY

1974 • 50 citations

Transport and Discharge of Exportable Proteins in Pancreatic Exocrine Cells: in Vitro Studies

1972 • 50 citations

Recent Advances in Renal Morphology

1982 • 49 citations

In vitro biosynthesis and membrane insertion of gamma-glutamyl transpeptidase.

1984 • 49 citations

Specific Selection of Host Cell Glycoproteins during Assembly of Murine Leukaemia Virus and Vesicular Stomatitis Virus: Presence of Thy-1 Glycoprotein and Absence of H-2, Pgp-1 and T-200 Glycoproteins on the Envelopes of these Virus Particles

1983 • 48 citations

Amino acid sequence of the Pronase-released heads of neuraminidase subtype N2 from the Asian strain A/Tokyo/3/67 of influenza virus

1982 • 47 citations

Delayed appearance of pseudotypes between vesicular stomatitis virus influenza virus during mixed infection of MDCK cells

1981 • 46 citations

Analysis of Sendai virus mRNAs with cDNA clones of viral genes and sequences of biologically important regions of the fusion protein.

1984 • 46 citations

Autoradiographic localisation of [3H]ouabain bound to cultured epithelial cell monolayers of MDCK cells

1981 • 45 citations

Junctional complexes in the preimplantation rabbit embryo

1975 • 44 citations

Localization of sodium pump sites in cat pancreas.

1981 • 44 citations

Aminopeptidase N is a marker for the apical pole of porcine thyroid epithelial cells in vivo and in culture

1981 • 43 citations

Carbohydrates of influenza virus. V. Oligosaccharides attached to individual glycosylation sites of the hemagglutinin of fowl plague virus

1984 • 42 citations

Highly purified basal lateral plasma membranes from rat duodenum. Physical criteria for purity

1979 • 41 citations

The amino acid sequence of the hydrophobic anchor of rabbit intestinal brush border aminopeptidase N

1982 • 40 citations

Fluidity and composition of brush border and basolateral membranes from rat kidney

1984 • 40 citations

Coated pits in action

1984 • 38 citations

Fluorescent membrane probes and the mechanism of maintenance of cellular asymmetry in epithelia.

1982 • 38 citations

A domain-specific marker for the hepatocyte plasma membrane. II. Ultrastructural localization of leucine aminopeptidase to the bile canalicular domain of isolated rat liver plasma membranes.

1984 • 36 citations

Membrane traffic in animal cells

1984 • 33 citations

Chapter 30 Selective Cultivation of Mammalian Epithelial Cells

1976 • 32 citations

Mitosis in rat thyroid epithelial cells in vivo

1979 • 32 citations

A domain-specific marker for the hepatocyte plasma membrane. III. Isolation of bile canalicular membrane by immunoadsorption.

1984 • 30 citations

Chemical and antigenic characterization of the carbohydrate side chains of an Asian (N2) influenza virus neuraminidases

1983 • 29 citations

Plasma membrane biogenesis in eukaryotic cells: translocation of newly synthesized lipid.

1984 • 28 citations

Heterogeneity of vesicular stomatitis virus particles: implications for virion assembly

1980 • 24 citations

Membrane Recycling in Secretory Cells: Pathway to the Golgi Complex

1982 • 24 citations

Quantitative immunoferritin localization of [Na+,K+]ATPase on canine hepatocyte cell surface.

1984 • 23 citations

Cell surface glycosaminoglycans of cell line MDCK derived from canine kidney.

1977 • 21 citations

Endocytosis, Membrane Recycling and Fcreceptor Function

1982 • 18 citations

Intracellular routes of apical and basolateral plasma membrane proteins to the surface of epithelial cells

1985 • 12 citations