Preparation and Characterization of Soluble Recombinant Heterotrimeric Complexes of Human Lymphotoxins and

The Fas Death Factor

1995 • 4,070 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Dimerization of cell surface receptors in signal transduction

1995 • 1,631 citations

The CD40 Antigen and its Ligand

1994 • 1,259 citations

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF

1988 • 1,105 citations

Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation

1993 • 1,073 citations

Tumor Necrosis Factor, Other Cytokines and Disease

1993 • 788 citations

Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface

1993 • 468 citations

Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness.

1995 • 436 citations

The Ligands and Receptors of the Lymphotoxin System

1995 • 262 citations

2 å crystal structure of an extracellular fragment of human CD40 ligand

1995 • 240 citations

Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells.

1992 • 183 citations

A new superfamily of cell surface proteins related to the nerve growth factor receptor

1991 • 172 citations

Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line.

1985 • 167 citations

Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor lines.

1996 • 153 citations

Characterization of surface lymphotoxin forms. Use of specific monoclonal antibodies and soluble receptors.

1995 • 146 citations

Lymphotoxin is expressed as a heteromeric complex with a distinct 33-kDa glycoprotein on the surface of an activated human T cell hybridoma.

1992 • 97 citations

Studies on the differing effects of tumor necrosis factor and lymphotoxin on the growth of several human tumor lines.

1989 • 78 citations

Lymphotoxin and an associated 33-kDa glycoprotein are expressed on the surface of an activated human T cell hybridoma.

1991 • 68 citations

Efficient purification of recombinant human tumor necrosis factor beta from Escherichia coli yields biologically active protein with a trimeric structure that binds to both tumor necrosis factor receptors

1991 • 68 citations

Production of lymphotoxin (LTα) and a soluble dimeric form of its receptor using the baculovirus expression system

1994 • 45 citations

Aspartic acid 50 and tyrosine 108 are essential for receptor binding and cytotoxic activity of tumour necrosis factor beta (lymphotoxin)

1991 • 45 citations

Structural and functional domains in human tumour necrosis factors

1991 • 37 citations

Bacterial Expression, Facile Purification and Properties of Recombinant Human Lymphotoxin (Tumor Necrosis Factor Beta)

1989 • 21 citations

Glycosylation and high‐level secretion of human tumour necrosis factor‐beta in recombinant baculovirus‐infected insect cells

1993 • 18 citations

N-Linked Sugar Chain Structure of Recombinant Human Lymphotoxin Produced by CHO Cells: The Functional Role of Carbohydrate as to Its Lectin-like Character and Clearance Velocity

1993 • 15 citations

Characterization of recombinant human lymphotoxin (tumor necrosis factor-β) produced by a mammalian cell line

1989 • 12 citations

Rapid Purification of Recombinant Human Tumor Necrosis Factor Beta

1994 • 5 citations