The Cytoplasmic Domain of the Lymphotoxin-β Receptor Mediates Cell Death in HeLa Cells

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

1996 • 3,065 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

1995 • 2,436 citations

Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

1996 • 2,306 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

The Receptor for the Cytotoxic Ligand TRAIL

1997 • 1,755 citations

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

1997 • 1,694 citations

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

1997 • 1,506 citations

A novel domain within the 55 kd TNF receptor signals cell death

1993 • 1,302 citations

RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1995 • 964 citations

Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis

1997 • 797 citations

LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

1998 • 760 citations

The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues

1998 • 710 citations

Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95

1996 • 653 citations

Distinct Roles in Lymphoid Organogenesis for Lymphotoxins α and β Revealed in Lymphotoxin β–Deficient Mice

1997 • 590 citations

Caspases and caspase inhibitors

1997 • 573 citations

RAIDD is a new 'death' adaptor molecule

1997 • 547 citations

Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.

1990 • 396 citations

Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs.

1996 • 392 citations

Self-association of the “Death Domains” of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 Effects

1995 • 383 citations

TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor

1996 • 343 citations

Lymph Node Genesis Is Induced by Signaling through the Lymphotoxin β Receptor

1998 • 294 citations

LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer.

1998 • 277 citations

Interferon-γ Modulates a p53-independent Apoptotic Pathway and Apoptosis-related Gene Expression

1997 • 276 citations

Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor.

1990 • 263 citations

The Ligands and Receptors of the Lymphotoxin System

1995 • 262 citations

Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor

1997 • 219 citations

Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB

1997 • 168 citations

Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation.

1998 • 163 citations

Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor lines.

1996 • 153 citations

Direct interaction of hepatitis C virus core protein with the cellular lymphotoxin-beta receptor modulates the signal pathway of the lymphotoxin-beta receptor

1997 • 148 citations

Characterization of surface lymphotoxin forms. Use of specific monoclonal antibodies and soluble receptors.

1995 • 146 citations

Overexpression of the p80 TNF Receptor Leads to TNF-Dependent Apoptosis, Nuclear Factor-κB Activation, and c-Jun Kinase Activation

1998 • 128 citations

Mouse lymphotoxin-beta receptor. Molecular genetics, ligand binding, and expression.

1995 • 118 citations

Dominant Negative Mutants of TRAF3 Reveal an Important Role for the Coiled Coil Domains in Cell Death Signaling by the Lymphotoxin-β Receptor

1997 • 83 citations

Activation of the lymphotoxin beta receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells.

1997 • 78 citations

Lymphotoxin β Receptor Triggering Induces Activation of the Nuclear Factor κB Transcription Factor in Some Cell Types

1996 • 70 citations

Induced Expression of Trimerized Intracellular Domains of the Human Tumor Necrosis Factor (TNF) p55 Receptor Elicits TNF Effects

1997 • 68 citations

Aggregation of the intracellular domain of the type 1 tumor necrosis factor receptor defined by the two-hybrid system.

1994 • 61 citations

Serine/Threonine Kinase Activity Associated with the Cytoplasmic Domain of the Lymphotoxin-β Receptor in HepG2 Cells

1997 • 9 citations