Quantifying the Gurken Morphogen Gradient in Drosophila Oogenesis

An Introduction to the Bootstrap

1994 • 39,661 citations

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

The development of Drosophila melanogaster

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DEVELOPMENT IN DROSOPHILA MELANOGASTER

1927 • 2,909 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

Capturing complex 3D tissue physiology in vitro

2006 • 2,187 citations

All of Statistics: A Concise Course in Statistical Inference

2012 • 1,000 citations

An Introduction to the Bootstrap.

1994 • 1,000 citations

Developmental genetics of oogenesis

1993 • 858 citations

Morphogen gradient interpretation

2001 • 738 citations

All Of Statistic A Concise Course In Statistical Inference

2003 • 682 citations

Dynamic control of positional information in the early Drosophila embryo

2004 • 577 citations

The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein.

1993 • 567 citations

Feedback control of intercellular signalling in development

2000 • 535 citations

Robustness of the BMP morphogen gradient in Drosophila embryonic patterning

2002 • 463 citations

The drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGFα-like protein

1993 • 443 citations

Morphogens, their identification and regulation

2004 • 437 citations

folded gastrulation, cell shape change and the control of myosin localization

2005 • 408 citations

Do Morphogen Gradients Arise by Diffusion?

2002 • 403 citations

Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster

1987 • 373 citations

Multiplex Detection of RNA Expression in Drosophila Embryos

2004 • 367 citations

Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination.

1995 • 312 citations

Diffusion and scaling during early embryonic pattern formation

2005 • 311 citations

Drosophila Dpp Morphogen Movement Is Independent of Dynamin-Mediated Endocytosis but Regulated by the Glypican Members of Heparan Sulfate Proteoglycans

2004 • 297 citations

Self-Enhanced Ligand Degradation Underlies Robustness of Morphogen Gradients

2003 • 292 citations

Facilitated Transport of a Dpp/Scw Heterodimer by Sog/Tsg Leads to Robust Patterning of the Drosophila Blastoderm Embryo

2005 • 291 citations

The maternal ventralizing locus torpedo is allelic to faint little ball, an embryonic lethal, and encodes the Drosophila EGF receptor homolog

1989 • 268 citations

An Autoregulatory Cascade of EGF Receptor Signaling Patterns the Drosophila Egg

1998 • 247 citations

All of Statistics: A Concise Course in Statistical Inference

2004 • 241 citations

A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands

1981 • 236 citations

Signaling by the Drosophila epidermal growth factor receptor pathway during development

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Requirement for phosphorylation and localization of the Bicaudal-D protein in Drosophila oocyte differentiation

1991 • 230 citations

The Transmembrane Molecule Kekkon 1 Acts in a Feedback Loop to Negatively Regulate the Activity of the Drosophila EGF Receptor during Oogenesis

1999 • 210 citations

Spatially Restricted Expression of pipe in the Drosophila Egg Chamber Defines Embryonic Dorsal–Ventral Polarity

1998 • 208 citations

7 EGF Receptor Signaling in Drosophila Oogenesis

1998 • 206 citations

Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc

1998 • 202 citations

Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis.

1994 • 182 citations

Formation of the BMP Activity Gradient in the Drosophila Embryo

2005 • 178 citations

Diffusion and Chemical Transformation

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Shaping Morphogen Gradients

2001 • 169 citations

Integration of epithelial patterning and morphogenesis inDrosophila ovarian follicle cells

2000 • 169 citations

The Drosophila TGF-α-like protein Gurken: expression and cellular localization during Drosophila oogenesis

1996 • 165 citations

Specific isoforms of Squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis

1999 • 159 citations

Signal dispersal and transduction through the endocytic pathway

2003 • 144 citations

Argos inhibits epidermal growth factor receptor signalling by ligand sequestration

2004 • 138 citations

Signalling by the Drosophila epidermal growth factor receptor is required for the specification and diversification of embryonic muscle progenitors

1998 • 132 citations

The shell game: patterning genes and morphological change

2005 • 129 citations

D-cbl, a Negative Regulator of the Egfr Pathway, Is Required for Dorsoventral Patterning in Drosophila Oogenesis

2000 • 122 citations

New fluorescent protein reporters for use with the drosophila gal4 expression system and for vital detection of balancer chromosomes

2002 • 120 citations

Modeling and computational analysis of EGF receptor-mediated cell communication inDrosophilaoogenesis

2002 • 118 citations

Dorsoventral axis formation in Drosophila depends on the correct dosage of the gene gurken

1994 • 115 citations

Incredible journey: how do developmental signals travel through tissue?

2004 • 115 citations

The relationship between ovarian and embryonic dorsoventral patterning in Drosophila

1994 • 113 citations

Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis

1998 • 112 citations

Dpp gradient formation by dynamin-dependent endocytosis: receptor trafficking and the diffusion model

2004 • 104 citations

Local Gurken signaling and dynamic MAPK activation during Drosophila oogenesis

1999 • 102 citations

The torso receptor localizes as well as transduces the spatial signal specifying terminal body pattern in Drosophila

1993 • 100 citations

Combined activities of Gurken and Decapentaplegic specify dorsal chorion structures of the Drosophila egg

2000 • 98 citations

Pointed, an ETS domain transcription factor, negatively regulates the EGF receptor pathway in Drosophila oogenesis

1996 • 95 citations

The origin of dorsoventral polarity inDrosophila

2003 • 90 citations

Tissue Engineering: Engineering Principles for the Design of Replacement Organs and Tissues

2004 • 84 citations

Drosophila bunched integrates opposing DPP and EGF signals to set the operculum boundary

2000 • 83 citations

The transmembrane region of Gurken is not required for biological activity, but is necessary for transport to the oocyte membrane in Drosophila

1999 • 78 citations

Mechanism of activation of theDrosophilaEGF Receptor by the TGFα ligand Gurken during oogenesis

2002 • 75 citations

Localized Requirements for windbeutel and pipe Reveal a Dorsoventral Prepattern within the Follicular Epithelium of the Drosophila Ovary

1998 • 73 citations

Molecular Principles of Animal Development

2002 • 70 citations

Molecular Principles of Animal Development

2002 • 70 citations

Mosaic analyses reveal the function ofDrosophila Rasin embryonic dorsoventral patterning and dorsal follicle cell morphogenesis

2002 • 51 citations

Discrete Models of Autocrine Cell Communication in Epithelial Layers

2003 • 49 citations

Border of Notch activity establishes a boundary between the two dorsal appendage tube cell types

2006 • 48 citations

Capicua regulates follicle cell fate in theDrosophilaovary through repression ofmirror

2006 • 47 citations

Quantitative analysis of the GAL4/UAS system inDrosophila oogenesis

2006 • 47 citations

Mechanisms of Gurken-dependentpiperegulation and the robustness of dorsoventral patterning inDrosophila

2002 • 44 citations

Computational analysis of EGFR inhibition by Argos

2005 • 42 citations

Bunched sets a boundary for Notch signaling to pattern anterior eggshell structures during Drosophila oogenesis

2005 • 42 citations

Genome wide analysis of transcript levels after perturbation of the EGFR pathway in the Drosophila ovary

2005 • 31 citations

Ligand trapping in epithelial layers and cell cultures

2004 • 21 citations

Systems-level questions in Drosophila oogenesis

2005 • 15 citations

Dorsoventral Patterning: A Direct Route from Ovary to Embryo

2002 • 12 citations