The shell game: patterning genes and morphological change

DEVELOPMENT IN DROSOPHILA MELANOGASTER

1927 • 2,909 citations

Ovarian development in Drosophila melanogaster

1970 • 1,436 citations

Developmental genetics of oogenesis

1993 • 858 citations

Tube Morphogenesis

2003 • 657 citations

The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein.

1993 • 567 citations

Drosophila Rhomboid-1 Defines a Family of Putative Intramembrane Serine Proteases

2001 • 561 citations

Characterization and cloning of fasciclin III: A glycoprotein expressed on a subset of neurons and axon pathways in Drosophila

1987 • 545 citations

Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology.

1991 • 504 citations

Polarization of both major body axes in Drosophila by gurken-torpedo signalling

1995 • 485 citations

cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila

1995 • 480 citations

Identification and behavior of epithelial stem cells in the Drosophila ovary

1995 • 460 citations

Towards a cellular and molecular understanding of neurulation

2001 • 444 citations

Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster

1987 • 373 citations

Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila

1991 • 372 citations

Regulated Intracellular Ligand Transport and Proteolysis Control EGF Signal Activation in Drosophila

2001 • 358 citations

Neural tube closure requires Dishevelled-dependent convergent extension of the midline

2002 • 351 citations

DE-Cadherin Is Required for Intercellular Motility during Drosophila Oogenesis

1999 • 330 citations

EcR isoforms inDrosophila: testing tissue-specific requirements by targeted blockade and rescue

2002 • 324 citations

Autosomal P[ovo D1 ] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras

1993 • 302 citations

Ectopic activation of torpedo/Egfr, a Drosophila receptor tyrosine kinase, dorsalizes both the eggshell and the embryo

1997 • 294 citations

The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila

1991 • 281 citations

Ecdysone response genes govern egg chamber development during mid-oogenesis in Drosophila

1999 • 259 citations

An Autoregulatory Cascade of EGF Receptor Signaling Patterns the Drosophila Egg

1998 • 247 citations

The control of cell motility and epithelial morphogenesis by Jun kinases

2004 • 243 citations

The TGF-β signaling pathway is essential for Drosophila oogenesis

1996 • 218 citations

Activation of a meiotic checkpoint regulates translation of Gurken during Drosophila oogenesis

1999 • 213 citations

okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis

1998 • 211 citations

The eggshell of Drosophila melanogaster: I. fine structure of the layers and regions of the wild-type eggshell

1980 • 209 citations

Spatially Restricted Expression of pipe in the Drosophila Egg Chamber Defines Embryonic Dorsal–Ventral Polarity

1998 • 208 citations

7 EGF Receptor Signaling in Drosophila Oogenesis

1998 • 206 citations

Intercellular signaling and the polarization of body axes during Drosophila oogenesis.

1996 • 202 citations

Respiratory Systems of Insect Egg Shells

1969 • 202 citations

Identifying loci required for follicular patterning using directed mosaics

1998 • 202 citations

Dorsal Gradient Networks in the Drosophila Embryo

2002 • 193 citations

Drosophila nonmuscle myosin II has multiple essential roles in imaginal disc and egg chamber morphogenesis

1996 • 189 citations

Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis.

1994 • 182 citations

Intercellular Cytoplasm Transport during Drosophila Oogenesis

1994 • 174 citations

Two signalling pathways specify localised expression of the Broad-Complex in Drosophila eggshell patterning and morphogenesis

1997 • 174 citations

An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint control

2003 • 170 citations

Integration of epithelial patterning and morphogenesis inDrosophila ovarian follicle cells

2000 • 169 citations

The involvement of the Notch locus in Drosophila oogenesis

1992 • 166 citations

Coordinately and differentially mutable activities of torpedo, the Drosophila melanogaster homolog of the vertebrate EGF receptor gene.

1989 • 163 citations

Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis

1993 • 149 citations

Profilin is required for posterior patterning of the Drosophila oocyte

1996 • 146 citations

Activation of a Meiotic Checkpoint during Drosophila Oogenesis Regulates the Translation of Gurken through Chk2/Mnk

2002 • 143 citations

Localized Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1

1997 • 131 citations

The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis

1996 • 131 citations

The receptor tyrosine phosphatase Dlar and integrins organize actin filaments in the Drosophila follicular epithelium

2001 • 125 citations

Stage-specific apoptotic patterns during Drosophila oogenesis

2000 • 123 citations

Signal transduction by a protease cascade

1999 • 119 citations

Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis

1998 • 112 citations

The Drosophila gene fs(2)cup interacts with otu to define a cytoplasmic pathway required for the structure and function of germ-line chromosomes

1997 • 111 citations

Drosophila chorion genes: Cracking the eggshell's secrets

1991 • 109 citations

loco encodes an RGS protein required for Drosophila glial differentiation

1999 • 109 citations

Morphogenesis of the eggshells in Drosophila

2000 • 104 citations

Studies in Genetics 1

1917 • 103 citations

Local Gurken signaling and dynamic MAPK activation during Drosophila oogenesis

1999 • 102 citations

GENETIC ANALYSIS OF THE ACTIN CYTOSKELETON IN THE DROSOPHILA OVARY

1997 • 102 citations

The neurogenic locus brainiac cooperates with the Drosophila EGF receptor to establish the ovarian follicle and to determine its dorsal-ventral polarity

1992 • 99 citations

Combined activities of Gurken and Decapentaplegic specify dorsal chorion structures of the Drosophila egg

2000 • 98 citations

Pointed, an ETS domain transcription factor, negatively regulates the EGF receptor pathway in Drosophila oogenesis

1996 • 95 citations

The homeobox gene mirror links EGF signalling to embryonic dorso-ventral axis formation through Notch activation

2000 • 93 citations

The origin of dorsoventral polarity inDrosophila

2003 • 90 citations

bullwinkle is required for epithelial morphogenesis during Drosophila oogenesis

2004 • 85 citations

Drosophila bunched integrates opposing DPP and EGF signals to set the operculum boundary

2000 • 83 citations

The Drosophila spn-D Gene Encodes a RAD51C-Like Protein That Is Required Exclusively During Meiosis

2003 • 82 citations

Role of Bicaudal-D in patterning the Drosophila egg chamber in mid-oogenesis

1996 • 78 citations

Drosophila rhino Encodes a Female-Specific Chromo-domain Protein That Affects Chromosome Structure and Egg Polarity

2001 • 76 citations

Phenotypic analysis of null mutants for DE‐cadherin and Armadillo in Drosophila ovaries reveals distinct aspects of their functions in cell adhesion and cytoskeletal organization

1997 • 71 citations

Juxtaposition between two cell types is necessary for dorsal appendage tube formation

2004 • 67 citations

Dynamics of apoptosis in the ovarian follicle cells during the late stages of Drosophila oogenesis

2002 • 64 citations

Drosophila egghead Encodes a β1,4-Mannosyltransferase Predicted to Form the Immediate Precursor Glycosphingolipid Substrate for brainiac

2003 • 59 citations

The Drosophila JNK Pathway Controls the Morphogenesis of the Egg Dorsal Appendages and Micropyle

2001 • 57 citations

Establishment of dorsal-ventral polarity of theDrosophilaegg requirescapicuaaction in ovarian follicle cells

2001 • 56 citations

A role for the DP subunit of the E2F transcription factor in axis determination during Drosophila oogenesis

2000 • 52 citations

Top–DER- and Dpp-dependent requirements for the Drosophila fos/kayak gene in follicular epithelium morphogenesis

2001 • 51 citations

Mosaic analyses reveal the function ofDrosophila Rasin embryonic dorsoventral patterning and dorsal follicle cell morphogenesis

2002 • 51 citations

The Drosophila bunched gene is a homologue of the growth factor stimulated mammalian TSC-22 sequence and is required during oogenesis

1997 • 51 citations

The Drosophila melanogaster brainiac Protein Is a Glycolipid-specific β1,3N-Acetylglucosaminyltransferase

2002 • 50 citations

Cct1, a phosphatidylcholine biosynthesis enzyme, is required forDrosophilaoogenesis and ovarian morphogenesis

2003 • 50 citations

bullwinkleandsharkregulate dorsal-appendage morphogenesis inDrosophilaoogenesis

2003 • 49 citations

The transcriptional factor CF2 is a mediator of EGF-R-activated dorsoventral patterning in Drosophila oogenesis.

1996 • 47 citations

The Drosophila Female Sterile Mutation twin peaks Is a Novel Allele of tramtrack and Reveals a Requirement for Ttk69 in Epithelial Morphogenesis

2003 • 42 citations

Mutations in the Drosophila gene bullwinkle cause the formation of abnormal eggshell structures and bicaudal embryos

1995 • 41 citations

Differential Activity of Ras1 during Patterning of the Drosophila Dorsoventral Axis

1996 • 41 citations

Drosophila puckered regulates Fos/Jun levels during follicle cell morphogenesis

2001 • 41 citations

The Drosophila G-protein-coupled receptor kinase homologue Gprk2 is required for egg morphogenesis

1997 • 39 citations

Post-transcriptional regulation of gurken by encore is required for axis determination in Drosophila

1997 • 39 citations

The Mirror transcription factor links signalling pathways in Drosophila oogenesis

2000 • 38 citations

Genome wide analysis of transcript levels after perturbation of the EGFR pathway in the Drosophila ovary

2005 • 31 citations

Encore is a member of a novel family of proteins and affects multiple processes inDrosophilaoogenesis

2000 • 31 citations

Ras1 Interacts With Multiple New Signaling and Cytoskeletal Loci in Drosophila Eggshell Patterning and Morphogenesis

2001 • 31 citations

Expression of fringe is down regulated by Gurken/Epidermal Growth Factor Receptor signalling and is required for the morphogenesis of ovarian follicle cells

2000 • 30 citations

Gprk2 Controls cAMP Levels in Drosophila Development

2001 • 24 citations

Temporal comparison of Broad-Complex expression during eggshell-appendage patterning and morphogenesis in two Drosophila species with different eggshell-appendage numbers

2003 • 23 citations

The Drosophila RGS protein Loco is required for dorsal/ventral axis formation of the egg and embryo, and nurse cell dumping

2001 • 18 citations

Misexpression ofargos, an inhibitor of EGFR signaling in oogenesis, leads to the production of bicephalic, ventralized, and lateralizedDrosophila melanogaster eggs

1999 • 15 citations

The actin membrane skeleton in Drosophila development.

1990 • 13 citations

Deleted Work

1955 • 0 citations