Ponticulin is an atypical membrane protein.
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References (79)
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F-actin binds to the cytoplasmic surface of ponticulin, a 17-kD integral glycoprotein from Dictyostelium discoideum plasma membranes.
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Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium.
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Dictyostelium discoideum plasma membranes contain an actin-nucleating activity that requires ponticulin, an integral membrane glycoprotein.
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Indirect immunofluorescence localization of ponticulin in motile cells
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The integral membrane protein, ponticulin, acts as a monomer in nucleating actin assembly.
1993 • 38 citations
Replacement of the phospholipid-anchor in the contact site A glycoprotein of D. discoideum by a transmembrane region does not impede cell adhesion but reduces residence time on the cell surface
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Direct binding of F‐actin to ponticulin, an Integral plasma membrane glycoprotein
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Ponticulin, a developmentally‐regulated plasma membrane glycoprotein, mediates actin binding and nucleation
1990 • 22 citations
A cleavable N-terminal signal peptide is not a prerequisite for the biosynthesis of glycosylphosphatidylinositol-anchored proteins.
1994 • 20 citations
Protein sequence and structure relationship ARMA spectral analysis: application to membrane proteins
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Developmental changes in protein composition and the actin-binding protein ponticulin in Dictyostelium discoideum plasma membranes purified by an improved method
1989 • 13 citations
[5] F-actin affinity chromatography of detergent-solubilized plasma membranes: Purification and initial characterization of ponticulin from Dictyostelium discoideum
1991 • 10 citations
Deleted Work
1955 • 0 citations