Crystal Structure of Defensin HNP-3, an Amphiphilic Dimer: Mechanisms of Membrane Permeabilization

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.

1987 • 2,216 citations

Defensins. Natural peptide antibiotics of human neutrophils.

1985 • 1,411 citations

Resolution of phase ambiguity in macromolecular crystallography

1985 • 1,040 citations

Interactive computer graphics: FRODO

1985 • 848 citations

A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-Å resolution

1982 • 710 citations

Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity.

1989 • 695 citations

Chain reversals in proteins

1973 • 652 citations

Stereochemically restrained refinement of macromolecular structures

1985 • 614 citations

Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes.

1990 • 540 citations

Primary structures of three human neutrophil defensins.

1985 • 529 citations

Direct inactivation of viruses by human granulocyte defensins

1986 • 525 citations

Conformation of twisted β-pleated sheets in proteins

1973 • 487 citations

Structure of the membrane-pore-forming fragment of colicin A

1989 • 333 citations

The structure of melittin. I. Structure determination and partial refinement.

1982 • 307 citations

Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes

1984 • 306 citations

Three-Dimensional Structure at 0.86 Å of the Uncomplexed form of the Transmembrane Ion Channel Peptide Gramicidin A

1988 • 292 citations

The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study

1988 • 282 citations

In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes

1986 • 257 citations

The interaction of bee melittin with lipid bilayer membranes

1978 • 256 citations

The Gramicidin Pore: Crystal Structure of a Cesium Complex

1988 • 247 citations

The beta bulge: a common small unit of nonrepetitive protein structure.

1978 • 237 citations

Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils.

1985 • 234 citations

Purification and Characterization of Human Neutrophil Peptide 4, a Novel Member of the Defensin Family

1989 • 222 citations

Folding patterns of porin and bacteriorhodopsin.

1985 • 206 citations

Three-dimensional structure of the "long" neurotoxin from cobra venom.

1980 • 201 citations

The stability and properties of bimolecular lipid leaflets in aqueous solutions

1963 • 200 citations

The crystal structure of a hydrated gramicidin S–urea complex

1978 • 188 citations

Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes

1985 • 180 citations

Orthorhombic crystals and three-dimensional structure of the potent toxin II from the scorpion Androctonus australis Hector.

1988 • 159 citations

Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin

1987 • 132 citations

Molecular design of PhoE porin and its functional consequences

1989 • 108 citations

Purification and antimicrobial properties of three defensins from rat neutrophils

1989 • 107 citations

Solution structures of the rabbit neutrophil defensin NP-5

1988 • 105 citations

Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity

1985 • 97 citations

Nuclear magnetic resonance investigation of the conformation of δ-haemolysin bound to dodecylphosphocholine micelles

1987 • 82 citations

CardiotoxinV4II fromNaja mossambica mossambica

1990 • 79 citations

Barrier properties of lecithin/lysolecithin mixtures

1975 • 72 citations

Two-dimensional NMR studies of the antimicrobial peptide NP-5

1987 • 64 citations

Architecture of scorpion neurotoxins: a class of membrane-binding proteins

1981 • 57 citations

Analysis of mutations in the transmembrane region of the aspartate chemoreceptor in Escherichia coli.

1986 • 54 citations

Phagocyte defects

1986 • 45 citations

Defensins mediate the microbicidal activity of human neutrophil granule extract against Acinetobacter calcoaceticus

1987 • 44 citations

Oxygen-Independent Bactericidal Systems: Mechanisms and Disorders

1988 • 41 citations

Molecular Structure of Charybdotoxin, a Pore-Directed Inhibitor of Potassium Ion Channels

1990 • 35 citations

The structure of porin from Rhodobacter capsulatus at 0.6 nm resolution

1989 • 27 citations

Characterization of two crystal forms of human defensin neutrophil cationic peptide 1, a naturally occurring antimicrobial peptide of leukocytes.

1988 • 22 citations