The molecular basis for alternative splicing of the CABP 1 transcripts inDictyostelium discoideum

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic culture

1970 • 1,142 citations

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

1984 • 947 citations

A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs

1988 • 747 citations

ALTERNATIVE SPLICING: A UBIQUITOUS MECHANISM FOR THE GENERATION OF MULTIPLE PROTEIN ISOFORMS FROM SINGLE GENES

1987 • 712 citations

Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins

1984 • 686 citations

COMPLEX TRANSCRIPTIONAL UNITS: DIVERSITY IN GENE EXPRESSION BY ALTERNATIVE RNA PROCESSING

1986 • 486 citations

The AU-rich sequences present in the introns of plant nuclear pre-mRNAs are required for splicing

1989 • 396 citations

Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA

1986 • 389 citations

A bacteriophage lambda vector for cloning large DNA fragments made with several restriction enzymes

1980 • 379 citations

A minimal intron length but no specific internal sequence is required for splicing the large rabbit β-globin intron

1984 • 328 citations

Developmental regulation of a dictyostelium gene encoding a protein homologous to mammalian ras protein

1984 • 267 citations

Fluorographic detection of radioactivity in polyacrylamide gels with 2,5-diphenyloxazole in acetic acid and its comparison with existing procedures

1983 • 264 citations

Alternative processing of mRNAs encoding mammalian chromosomal high-mobility-group proteins HMG-I and HMG-Y.

1989 • 241 citations

Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit β-globin gene

1983 • 235 citations

Calcium‐sensitive non‐muscle α‐actinin contains EF‐hand structures and highly conserved regions

1987 • 205 citations

Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro

1985 • 172 citations

Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library.

1989 • 171 citations

Codon usage and gene expression level inDictyosteiium discoidtum: highly expressed genes do [prefer[ optimal codons

1989 • 165 citations

Mutations in a yeast intron demonstrate the importance of specific conserved nucleotides for the two stages of nuclear mRNA splicing

1986 • 150 citations

Sequence organization inDictyostelium: unique structure at the 5′-ends of protein coding genes

1983 • 134 citations

A point mutation in the conserved hexanucleotide at a yeast 5′ splice junction uncouples recognition, cleavage, and ligation

1985 • 129 citations

Cyclic AMP Regulation of Early Gene Expression in Dictyostelium discoideum: Mediation via the Cell Surface Cyclic AMP Receptor

1987 • 127 citations

A quantitative analysis of the effects of 5′ junction and TACTAAC box mutants and mutant combinations on yeast mRNA splicing

1985 • 115 citations

Multiple actin-based motor genes in Dictyostelium.

1989 • 110 citations

Nuclear Pre-mRNA Processing in Plants: Distinct Modes of 3′-Splice-Site Selection in Plants and Animals

1988 • 99 citations

Two vectors which facilitate gene manipulation and a simplified transformation procedure for Dictyostelium discoideum

1987 • 86 citations

Alternative Processing of mRNAs Encoding Mammalian Chromosomal High-Mobility-Group Proteins HMG-I and HMG-Y

1989 • 84 citations

Identification of the sequences controlling cyclic AMP regulation and cell-type-specific expression of a prestalk-specific gene in Dictyostelium discoideum.

1987 • 74 citations

Splicing of plant pre-mRN As in animal systems and vice versa

1987 • 65 citations

Multiple copies of a G-rich element upstream of a cAMP-inducible Dictyostelium gene are necessary but not sufficient for efficient gene expression

1988 • 59 citations

Spore coat genes SP60 and SP70 of Dictyostelium discoideum.

1989 • 55 citations

Primary structure and regulation of vegetative specific genes ofDictyostelium discoideum

1989 • 48 citations

An 80-bp cis-acting regulatory region controls cAMP and development regulation of a prestalk gene in Dictyostelium.

1988 • 46 citations

Structure and sequence of a UDP glucose pyrophosphorylase gene ofDictyostelium discoideum

1987 • 42 citations

Intervening sequences in a Dictyostelium gene that encodes a low abundance class mRNA

1980 • 41 citations

The Cyclic Nucleotide Phosphodiesterase Gene of Dictyostelium discoideum Utilizes Alternate Promoters and Splicing for the Synthesis of Multiple mRNAs

1989 • 41 citations

Identification of multiple cyclic AMP-binding proteins in developing Dictyostelium discoideum cells.

1986 • 27 citations

Nucleotide sequence and characterization of the transcript of aDictyosteliumribosomal protein gene

1987 • 25 citations

Identification of the Sequences Controlling Cyclic AMP Regulation and Cell-Type-Specific Expression of a Prestalk-Specific Gene in Dictyostelium discoideum

1987 • 23 citations

A pair of tandemly repeated genes code for gp24, a putative adhesion protein of Dictyostelium discoideum.

1990 • 21 citations

A developmentally regulated gene product from Dictyostelium discoideum shows high homology to human α‐L‐fucosidase

1989 • 21 citations

Expression and organization of BP74, a cyclic AMP-regulated gene expressed during Dictyostelium discoideum development.

1989 • 15 citations

Complementation of aDictyoslelium discoideumthymidylate synthase mutation with the mouse gene provides a new selectable marker for transformation

1989 • 14 citations

Notes: Spore Coat Genes SP60 and SP70 of Dictyostelium discoideum

1989 • 14 citations

A single base exchange in an intron of the Dictyostelium discoideum alpha-actinin gene inhibits correct splicing of the RNA but allows transport to the cytoplasm and translation.

1990 • 14 citations

Developmental Regulation of DNase I-Hypersensitive Sites in Dictyostelium discoideum

1987 • 11 citations

Expression of an altered cAMP binding protein by rapid-developing strains of Dictyostelium discoideum

1987 • 7 citations

Expression and Organization of BP74, a Cyclic AMP-Regulated Gene Expressed during Dictyostelium discoideum Development

1989 • 4 citations