Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium.

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

1993 • 1,124 citations

On the Crawling of Animal Cells

1993 • 1,020 citations

Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination

1987 • 984 citations

Cellular motions and thermal fluctuations: the Brownian ratchet

1993 • 874 citations

The Development of Dictyostelium Discoideum

1982 • 664 citations

Life at the Leading Edge: The Formation of Cell Protrusions

1993 • 442 citations

Dystrophin abnormalities in Duchenne/Becker muscular dystrophy

1989 • 330 citations

Myosin I is located at the leading edges of locomoting Dictyostelium amoebae

1989 • 323 citations

The Role of Actin Polymerization in Cell Motility

1991 • 301 citations

Gene replacement in Dictyostelium: generation of myosin null mutants.

1989 • 299 citations

Coronin, an actin binding protein of Dictyostelium discoideum localized to cell surface projections, has sequence similarities to G protein beta subunits.

1991 • 294 citations

Dictyostelium mutants lacking the cytoskeletal protein coronin are defective in cytokinesis and cell motility.

1993 • 249 citations

The cytoskeleton of the resting human blood platelet: structure of the membrane skeleton and its attachment to actin filaments.

1991 • 233 citations

Proton pumps populate the contractile vacuoles of Dictyostelium amoebae.

1993 • 222 citations

THE CONTRACTILE BASIS OF AMOEBOID MOVEMENT

1973 • 220 citations

Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein.

1987 • 166 citations

Association of gelsolin with actin filaments and cell membranes of macrophages and platelets.

1989 • 151 citations

Redundancy in the microfilament system: Abnormal development of dictyostelium cells lacking two F-actin cross-linking proteins

1992 • 151 citations

The unconventional myosin encoded by the myoA gene plays a role in Dictyostelium motility.

1993 • 148 citations

Functional Elements of the Cytoskeleton in the Early Drosophila Embryo

1993 • 144 citations

Myosin IB null mutants of Dictyostelium exhibit abnormalities in motility

1991 • 143 citations

Generation and characterization of Dictyostelium cells deficient in a myosin I heavy chain isoform.

1990 • 137 citations

Genetics of the red cell membrane skeleton.

1990 • 132 citations

Actin-dependent motile forces and cell motility

1994 • 129 citations

Extension of filopodia by motor‐dependent actin assembly

1992 • 127 citations

Clathrin heavy chain is required for pinocytosis, the presence of large vacuoles, and development in Dictyostelium.

1992 • 126 citations

Targeted disruption of the ABP-120 gene leads to cells with altered motility.

1992 • 125 citations

Recent quantitative studies of actin filament turnover during cell locomotion

1993 • 119 citations

The yeast actin cytoskeleton

1994 • 114 citations

A Dictyostelium mutant lacking an F-actin cross-linking protein, the 120-kD gelation factor.

1990 • 108 citations

Molecular insights into eukaryotic chemotaxis

1991 • 103 citations

A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis.

1989 • 100 citations

Length distribution of F-actin in Dictyostelium discoideum.

1990 • 96 citations

Hisactophilin, a histidine-rich actin-binding protein from Dictyostelium discoideum

1989 • 94 citations

F-actin binds to the cytoplasmic surface of ponticulin, a 17-kD integral glycoprotein from Dictyostelium discoideum plasma membranes.

1987 • 93 citations

The purification and characterization of Dictyostelium discoideum plasma membranes

1977 • 83 citations

Sequence, expression pattern, intracellular localization, and targeted disruption of the Dictyostelium myosin ID heavy chain isoform

1993 • 81 citations

Streaming in Cytoplasm Dissociated from the Giant Amœba, Chaos Chaos

1960 • 80 citations

Genetic Approaches to Molecular Motors

1992 • 80 citations

Developmental consequences of the lack of myosin heavy chain in Dictyostelium discoideum

1988 • 71 citations

The dictyostelium essential light chain is required for myosin function

1992 • 68 citations

Dictyostelium annexin VII (synexin). cDNA sequence and isolation of a gene disruption mutant.

1991 • 68 citations

1 Lateral Inhibition and Pattern Formation in Dictyostelium

1993 • 67 citations

Toward a New Concept of Cell Motility: Cytoskeletal Dynamics in Amoeboid Movement and Cell Division

1993 • 63 citations

Sensory transduction in eukaryotes

1991 • 58 citations

Cell division in Aspergillus

1992 • 57 citations

Dynamics of the Dictyostelium cytoskeleton during chemotaxis.

1992 • 57 citations

Dictyostelium discoideum: Molecular Approaches to Cell Biology

1987 • 56 citations

A membrane cytoskeleton from Dictyostelium discoideum. II. Integral proteins mediate the binding of plasma membranes to F-actin affinity beads.

1984 • 55 citations

Isolation of an immunoreactive analogue of brain fodrin that is associated with the cell cortex of Dictyostelium amoebae

1988 • 52 citations

Ponticulin is an atypical membrane protein.

1994 • 51 citations

Biophysics of the leading lamella

1988 • 51 citations

Dictyostelium discoideum plasma membranes contain an actin-nucleating activity that requires ponticulin, an integral membrane glycoprotein.

1990 • 44 citations

Chapter 5 Purification and Characterization of Dictyostelium discoideum Plasma Membranes

1987 • 43 citations

The integral membrane protein, ponticulin, acts as a monomer in nucleating actin assembly.

1993 • 38 citations

Patterns in Dictyostelium discoideum: the role of myosin II in the transition from the unicellular to the multicellular phase

1993 • 35 citations

Direct binding of F‐actin to ponticulin, an Integral plasma membrane glycoprotein

1991 • 35 citations

A membrane cytoskeleton from Dictyostelium discoideum. III. Plasma membrane fragments bind predominantly to the sides of actin filaments.

1984 • 32 citations

Binding and assembly of actin filaments by plasma membranes from Dictyostelium discoideum.

1986 • 32 citations

Actin‐Associated proteins in Dictyostelium discoideum

1990 • 30 citations

Quantification of transformation efficiency using a new method for clonal growth and selection of axenic Dictyostelium cells

1990 • 30 citations

TheDictyostelium discoideum 30,000 dalton protein contributes to phagocytosis

1992 • 29 citations

Genetic Alteration of Proteins in Actin-Based Motility Systems

1991 • 26 citations

Chapter 6 Endocytosis and Recognition Mechanisms in Dictyostelium discoideum

1987 • 26 citations

Ponticulin, a developmentally‐regulated plasma membrane glycoprotein, mediates actin binding and nucleation

1990 • 22 citations

Phagocytosis in Dictyostelium discoideum is inhibited by antibodies directed primarily against common carbohydrate epitopes of a major cell-surface plasma membrane glycoprotein

1989 • 19 citations

Solute Uptake by Dictyostelium discoideum and its Inhibition

1983 • 19 citations

The Dictyostelium Discoideum Plasma Membrane: A Model System for the Study of Actin-Membrane Interactions

1990 • 18 citations

Chapter 10 Ultrastructural Localization of Cytoskeletal Proteins in Dictyostelium Amoebae

1987 • 18 citations

Phenotypes of cytoskeletal mutants

1993 • 7 citations