Follicular dendritic cells help resting B cells to become effective antigen-presenting cells: induction of B7/BB1 and upregulation of major histocompatibility complex class II molecules.

Disruption of the murine IL-4 gene blocks Th2 cytokine responses

1993 • 1,197 citations

Intraclonal generation of antibody mutants in germinal centres

1991 • 1,083 citations

Maturation of the immune response in germinal centers

1991 • 904 citations

T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.

1990 • 745 citations

Sites of specific B cell activation in primary and secondary responses to T cell‐dependent and T cell‐independent antigens

1991 • 743 citations

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations.

1991 • 683 citations

CD19: Lowering the Threshold for Antigen Receptor Stimulation of B Lymphocytes

1992 • 673 citations

The Follicular Dendritic Cell: Its Role in Antigen Presentation in the Generation of Immunological Memory

1980 • 490 citations

CD21 is a ligand for CD23 and regulates IgE production

1992 • 479 citations

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers.

1992 • 456 citations

Germinal centres in T-cell-dependent antibody responses

1992 • 442 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

Follicular Dendritic Cells as Accessory Cells

1990 • 351 citations

Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation.

1982 • 320 citations

The Maintenance and Regulation of the Humoral Immune Response: Persisting Antigen and the Role of Follicular Antigen‐Binding Dendritic Cells as Accessory Cells

1980 • 313 citations

Interleukin-induced increase in Ia expression by normal mouse B cells.

1984 • 293 citations

Molecular Mechanisms of Transmembrane Signaling in B Lymphocytes

1987 • 279 citations

Relationship of germinal centers in lymphoid tissue to immunologic memory. VI. Transfer of B cell memory with lymph node cells fractionated according to their receptors for peanut agglutinin.

1983 • 274 citations

Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line

1985 • 244 citations

Growth control of activated, synchronized murine B cells by the C3d fragment of human complement

1985 • 238 citations

Follicular dendritic cell-dependent adhesion and proliferation of B cells in vitro.

1992 • 235 citations

A novel in vivo follicular dendritic cell-dependent iccosome-mediated mechanism for delivery of antigen to antigen-processing cells.

1988 • 228 citations

Germinal centre B cells: antigen specificity and changes in heavy chain class expression

1982 • 220 citations

Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations

1989 • 215 citations

B7, a B-cell-restricted antigen that identifies preactivated B cells.

1987 • 211 citations

Antigen presentation by normal B cells, B cell tumors, and macrophages: functional and biochemical comparison.

1982 • 199 citations

Novel pathways of antigen presentation for the maintenance of memory

1991 • 173 citations

Cognate interactions between helper T cells and B cells

1990 • 165 citations

Accessory cell requirements for the mixed-leukocyte reaction and polyclonal mitogens, as studied with a new technique for enriching blood dendritic cells

1988 • 147 citations

Antigen presentation by splenic B cells: resting B cells are ineffective, whereas activated B cells are effective accessory cells for T cell responses.

1985 • 145 citations

Germinal Centers and Antibody Production in Bone Marrow

1992 • 135 citations

Role of membrane immunoglobulin (Ig) crosslinking in membrane Ig-mediated, major histocompatibility-restricted T cell-B cell cooperation.

1985 • 131 citations

In vivo obtained antigen presented by germinal center B cells to T cells in vitro.

1988 • 122 citations

Studies on the immunogenicity and tolerogenicity of T-independent antigens.

1983 • 117 citations

B cell activation. I. Anti-immunoglobulin-induced receptor cross-linking results in a decrease in the plasma membrane potential of murine B lymphocytes.

1983 • 112 citations

Isolated follicular dendritic cells: cytochemical antigen localization, Nomarski, SEM, and TEM morphology.

1985 • 111 citations

Follicular dendritic cells in suspension: identification, enrichment, and initial characterization indicating immune complex trapping and lack of adherence and phagocytic activity.

1985 • 110 citations

Antibody-forming cell induction during an early phase of germinal centre development and its delay with ageing.

1989 • 99 citations

Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human gamma 1.

1993 • 95 citations

Requirements for the processing of antigen by antigen-presenting B cells. II. Biochemical comparison of the fate of antigen in B cell tumors and macrophages.

1982 • 93 citations

H‐2‐restricted T‐B cell interactions involved in polyspecific B cell responses mediated by soluble antigen

1982 • 84 citations

The action of human C3 in soluble or cross‐linked form with resting and activated murine B lymphocytes

1985 • 79 citations

Presentation of antigen by B cells: functional dependence on radiation dose, interleukins, cellular activation, and differential glycosylation.

1985 • 78 citations

Activation of murine B lymphocytes by anti-immunoglobulin is an inductive signal leading to immunoglobulin secretion.

1980 • 77 citations

Polymeric C3dg primes human B lymphocytes for proliferation induced by anti-IgM.

1989 • 77 citations

The Central Role of Follicular Dendritic Cells in Lymphoid Tissues

1992 • 75 citations

Signals Involved in Germinal Center Reactions

1992 • 68 citations

Recruitment of virgin B cells into an immune response is restricted to activation outside lymphoid follicles.

1988 • 60 citations

Selective depression of thymus-independent anti-DNP antibody responses induced by adult but not neonatal splenectomy.

1985 • 52 citations

Follicular dendritic cells in the alternative antigen transport pathway: microenvironment, cellular events, age and retrovirus related alterations.

1992 • 44 citations

Follicular Dendritic Cells in the Regulation and Maintenance of Immune Responses

1984 • 35 citations

Proliferation of Germinal Center B Lymphocytes in vitro by Direct Membrane Contact with Follicular Dendritic Cells

1991 • 35 citations

Antigen-induced changes in phospholipid metabolism in antigen-binding B lymphocytes.

1987 • 34 citations

Extensive splenic B cell activation in IgMtransgenic mice

1990 • 24 citations

Increased Leukocyte Diversity and Responsiveness to B-Cell and T-Cell Mitogens in Cell Suspensions Prepared by Enzymatically Dissociating Murine Lymph Nodes

1986 • 19 citations

Comparison of lgD⁺ and lgD⁻ thoracic duct B lymphocytes as germinal center precursor cells in the rat

1991 • 12 citations