Molecular Mechanisms of Transmembrane Signaling in B Lymphocytes

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

1980 • 2,218 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

FRACTIONATION AND CHARACTERIZATION OF A CYCLIC ADENINE RIBONUCLEOTIDE FORMED BY TISSUE PARTICLES

1958 • 1,055 citations

Voltage-gated K+ channels in human T lymphocytes: a role in mitogenesis?

1984 • 734 citations

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

1984 • 447 citations

A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters

1985 • 446 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

Immunoglobulin Determinants on the Surface of Mouse Lymphoid Cells

1970 • 422 citations

K channels in T lymphocytes: a patch clamp study using monoclonal antibody adhesion

1984 • 308 citations

Interleukin-induced increase in Ia expression by normal mouse B cells.

1984 • 293 citations

Message Transmission: Receptor Controlled Adenylate Cyclase System

1984 • 275 citations

Currents carried by monovalent cations through calcium channels in mouse neoplastic B lymphocytes.

1985 • 239 citations

Anti-immunoglobulin, cytoplasmic free calcium, and capping in B lymphocytes.

1982 • 223 citations

Phorbol ester and diacylglycerol induce protein phosphorylation at tyrosine

1983 • 214 citations

IMMUNOGLOBULINS AS CELL RECEPTORS*

1971 • 209 citations

Volume-induced increase of anion permeability in human lymphocytes.

1982 • 202 citations

The activation of protein kinase C by biologically active lipid moieties of lipopolysaccharide.

1984 • 180 citations

B cell activation. VIII. Membrane immunoglobulins transduce signals via activation of phosphatidylinositol hydrolysis.

1984 • 180 citations

Similar Idiotypic Specificity for the Membrane IgD and IgM of Human B Lymphocytes

1975 • 179 citations

Membrane potential changes during mitogenic stimulation of mouse spleen lymphocytes

1980 • 159 citations

Stimulation of mouse lymphocytes by insoluble anti-mouse immunoglobulin

1975 • 154 citations

Regulation of the cellular and subcellular concentrations and distribution of cyclic nucleotide-dependent protein kinases.

1984 • 153 citations

Translocation of protein kinase C during membrane immunoglobulin-mediated transmembrane signaling in B lymphocytes.

1986 • 136 citations

Same Idiotypc of B‐Lymphocyte Membrane IgD and IgM. Formal Evidence for Monoclonality of Chronic Lymphocytic Leukemia Cells

1974 • 127 citations

Dissociation of two signals required for activation of resting B cells.

1982 • 123 citations

Anti-Ig induces release of inositol 1,4,5-trisphosphate, which mediates mobilization of intracellular Ca++ stores in B lymphocytes.

1986 • 121 citations

Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells.

1976 • 108 citations

B cell activation. III. B cell plasma membrane depolarization and hyper-Ia antigen expression induced by receptor immunoglobulin cross-linking are coupled.

1983 • 101 citations

Transmembrane signaling through B cell MHC class II molecules: anti-Ia antibodies induce protein kinase C translocation to the nuclear fraction.

1987 • 99 citations

Subcellular site and mechanism of vasopressin-stimulated hydrolysis of phosphoinositides in rat hepatocytes.

1984 • 89 citations

Altered subcellular distribution of protein kinase C (a phorbol ester receptor). Possible role in tumor promotion and the regulation of cell growth: relationship to changes in adenylate cyclase activity.

1985 • 88 citations

Volume regulation by human lymphocytes: Characterization of the ionic basis for regulatory volume decrease

1982 • 87 citations

Translocation of phospholipid/Ca2+-dependent protein kinase in B-lymphocytes activated by phorbol ester or cross-linking of membrane immunoglobulin

1986 • 85 citations

Antibodies reactive with class II antigens encoded for by the major histocompatibility complex inhibit human B cell activation.

1986 • 84 citations

Calcium transport and calcium-ATPase activity in human lymphocyte plasma membrane vesicles.

1981 • 84 citations

Effects of anti-Ia serum on mitogenic responses. I. Inhibition of the proliferative response to B cell mitogen, LPS, by specific anti-Ia sera.

1975 • 75 citations

Level of mIa expression on mitogen-stimulated murine B lymphocytes is dependent on position in cell cycle.

1983 • 75 citations

Increasing the intracellular Na+ concentration induces differentiation in a pre-B lymphocyte cell line.

1983 • 75 citations

Anti-immunoglobulin and phorbol ester induce phosphorylation of proteins associated with the plasma membrane and cytoskeleton in murine B lymphocytes.

1986 • 67 citations

Voltage-gated Ca2+ channel in mouse myeloma cells.

1983 • 64 citations

Acetycholine stimulation of the phosphodiesteratic cleavage of guinea pig brain phosphoinositides

1968 • 47 citations

Supernatant from a cloned helper T cell stimulates most small resting B cells to undergo increased I-A expression, blastogenesis, and progression through cell cycle.

1986 • 38 citations

Role of G-protein-receptor interaction in amplified phosphodiesterase activation of retinal rods.

1984 • 22 citations

Flow cytometric analysis of intracellular calcium mobilization

1987 • 11 citations

Changes in the expression of B cell surface markers on complement receptor-positive and complement receptor-negative B cells induced by phorbol myristate acetate.

1984 • 11 citations