Extensive splenic B cell activation in IgMtransgenic mice

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice

1988 • 1,562 citations

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

1989 • 1,015 citations

Properties of Monoclonal Antibodies to Mouse Ig Allotypes, H-2, and Ia Antigens

1979 • 993 citations

A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.

1984 • 308 citations

Introduction of a μ immunoglobulin gene into the mouse germ line: Specific expression in lymphoid cells and synthesis of functional antibody

1984 • 304 citations

Allelic Exclusion in Transgenic Mice That Express the Membrane form of Immunoglobulin μ

1987 • 293 citations

Use of the Avidin-Biotin Complex for Specific Staining of Biological Membranes in Electron Microscopy

1974 • 269 citations

Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line

1985 • 244 citations

AUTORADIOGRAPHIC STUDIES ON THE IMMUNE RESPONSE

1962 • 235 citations

IMMUNOGLOBULINS AS CELL RECEPTORS*

1971 • 209 citations

Autonomous activation of B and T cells in antigen-free mice

1986 • 184 citations

A transgenic immunoglobulin Mu gene prevents rearrangement of endogenous genes

1985 • 169 citations

AUTORADIOGRAPHIC STUDIES ON THE IMMUNE RESPONSE

1962 • 149 citations

Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains.

1988 • 138 citations

Monoclonal anti‐allotype antibody towards BALB/c IgM Analysis of specificity and site of a V‐C crossover in recombinant strain BALB‐Igh‐V^a/Igh‐C^b

1987 • 104 citations

Depletion of the predominant B-cell population in immunoglobulin µ heavy-chain transgenic mice

1987 • 102 citations

Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged Mu heavy chain gene

1986 • 101 citations

A monoclonal antibody against Igh6-4 determinant

1986 • 88 citations

IgM antibodies induce the production of antibodies of the same specificity.

1980 • 80 citations

Establishment of idiotypic helper T-cell repertoires early in life

1985 • 79 citations

Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice.

1989 • 71 citations

Expression of immunoglobulin delta chain causes allelic exclusion in transgenic mice

1987 • 70 citations

Natural effector T lymphocytes in normal mice.

1985 • 70 citations

Internal complementarities in the immune system: regulation of the expression of helper T-cell idiotypes.

1984 • 70 citations

Rearrangement and expression of endogenous immunoglobulin genes occur in many murine B cells expressing transgenic membrane IgM.

1988 • 55 citations

Isotype exclusion and transgene down-regulation in immunoglobulin-λ transgenic mice

1989 • 53 citations

Atlas of Blood Cells, Function and Pathology

1982 • 37 citations

Immune status of a μ, χ transgenic mouse line. Deficient response to bacterially related antigens

1989 • 34 citations

Antigen‐independent, IgM‐induced antibody responses: requirement for “recurrent” idiotypes

1982 • 33 citations

[42] Use of fluorescent antibodies in the study of lymphoid cell membrane molecules

1984 • 23 citations

Idiotypic characterization of antibody-induced antibody responses

1982 • 14 citations