Functional significance of the rapid regulation of brain estrogen action: Where do the estrogens come from?

The Physiology of Reproduction

1988 • 7,765 citations

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

1986 • 2,194 citations

A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling

2005 • 2,191 citations

Hormones, Brain and Behavior

2009 • 1,548 citations

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

2000 • 1,411 citations

Estrogen Actions in the Central Nervous System¹

1999 • 1,381 citations

Identity of an Estrogen Membrane Receptor Coupled to a G Protein in Human Breast Cancer Cells

2004 • 1,360 citations

Plasma Concentration of LH, FSH, Prolactin, Progesterone and Estradiol-17β Throughout the 4-Day Estrous Cycle of the Rat

1974 • 1,296 citations

The Control of Progesterone Secretion During the Estrous Cycle and Early Pseudopregnancy in the Rat: Prolactin, Gonadotropin and Steroid Levels Associated with Rescue of the Corpus Luteum of Pseudopregnancy¹²

1975 • 1,281 citations

Fundamental Neuroscience

2000 • 1,181 citations

Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells

1999 • 1,046 citations

Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors.

1999 • 1,029 citations

Functional role of estrogen metabolism in target cells: review and perspectives

1998 • 965 citations

Transdermal Testosterone Treatment in Women with Impaired Sexual Function after Oophorectomy

2000 • 946 citations

Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes

2003 • 787 citations

Virtual and biomolecular screening converge on a selective agonist for GPR30

2006 • 784 citations

An Introduction to Behavioral Endocrinology

1994 • 771 citations

Loss of Circadian Rhythmicity in Blood Testosterone Levels with Aging in Normal Men*

1983 • 770 citations

Aromatase—A Brief Overview

2002 • 704 citations

Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor

2003 • 697 citations

Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells

1977 • 686 citations

Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation

2000 • 662 citations

Characterization and measurement of dehydroepiandrosterone sulfate in rat brain.

1981 • 645 citations

Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor

1996 • 638 citations

Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons

2003 • 627 citations

ER-X: A Novel, Plasma Membrane-Associated, Putative Estrogen Receptor That Is Regulated during Development and after Ischemic Brain Injury

2002 • 546 citations

Sex-related hormonal influences on pain and analgesic responses

2000 • 539 citations

A corticosteroid Receptor in Neuronal Membranes

1991 • 522 citations

An Introduction to Behavioral Endocrinology

2001 • 512 citations

Acute Activation of Maxi-K Channels ( hSlo ) by Estradiol Binding to the β Subunit

1999 • 502 citations

Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription

1997 • 478 citations

Testosterone Patch Increases Sexual Activity and Desire in Surgically Menopausal Women with Hypoactive Sexual Desire Disorder

2005 • 465 citations

Rapid Signaling of Estrogen in Hypothalamic Neurons Involves a Novel G-Protein-Coupled Estrogen Receptor that Activates Protein Kinase C

2003 • 455 citations

Minireview: Aromatase and the Regulation of Estrogen Biosynthesis—Some New Perspectives

2001 • 453 citations

Safety and Efficacy of a Testosterone Patch for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women

2005 • 453 citations

Long-term and short-term electrophysiological effects of estrogen on the synaptic properties of hippocampal CA1 neurons

1992 • 449 citations

The endocrine stress-response and social status in the wild baboon

1982 • 444 citations

The G Protein-coupled Receptor GPR30 Mediates c-fos Up-regulation by 17β-Estradiol and Phytoestrogens in Breast Cancer Cells

2004 • 429 citations

GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release

2005 • 384 citations

Estrogen Induces the Akt-dependent Activation of Endothelial Nitric-oxide Synthase in Vascular Endothelial Cells

2001 • 377 citations

On the Control of Gonadotropin Secretion in the Rhesus Monkey

1974 • 377 citations

A new, nongenomic estrogen action: the rapid release of intracellular calcium.

1992 • 372 citations

Estradiol Activates Group I and II Metabotropic Glutamate Receptor Signaling, Leading to Opposing Influences on cAMP Response Element-Binding Protein

2005 • 372 citations

Male Sexual Behavior

2009 • 370 citations

Is brain estradiol a hormone or a neurotransmitter?

2006 • 369 citations

Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system.

1999 • 366 citations

Estrogen actions in the central nervous system

1999 • 364 citations

Anesthetic Effect of Steroid Hormones.

1941 • 363 citations

Experimental Induction of Puberty in the Infantile Female Rhesus Monkey

1980 • 349 citations

Neuroendocrinology of Reproduction

1981 • 345 citations

Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium

1999 • 336 citations

Cellular functions of plasma membrane estrogen receptors

2002 • 334 citations

Anatomical Distribution and Cellular Basis for High Levels of Aromatase Activity in the Brain of Teleost Fish: Aromatase Enzyme and mRNA Expression Identify Glia as Source

2001 • 293 citations

Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brain.

1996 • 283 citations

Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis

1990 • 280 citations

17β-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors

1997 • 278 citations

The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus

2000 • 274 citations

Classical Conditioning: Induction of Luteinizing Hormone and Testosterone Secretion in Anticipation of Sexual Activity

1980 • 272 citations

Sex difference and estrous cycle variations in amphetamine-elicited rotational behavior

1982 • 268 citations

Morphological abnormalities in the brains of estrogen receptor β knockout mice

2001 • 265 citations

Novel Neurotransmitters and Their Neuropsychiatric Relevance

2000 • 264 citations

Short-term changes in plasma levels of hormones during establishment and defense of a breeding territory in male song sparrows, Melospiza melodia

1985 • 261 citations

Minireview: A Plethora of Estrogen Receptors in the Brain: Where Will It End?

2003 • 261 citations

Plasma Testosterone Levels in the Male Rhesus: Influences of Sexual and Social Stimuli

1972 • 253 citations

Brain and behavior

1961 • 250 citations

Serum Androstenedione and Testosterone Levels During the Menstrual Cycle

1973 • 250 citations

Testosterone Signaling through Internalizable Surface Receptors in Androgen Receptor-free Macrophages

1999 • 245 citations

Distribution and regulation of telencephalic aromatase expression in the zebra finch revealed with a specific antibody

2000 • 242 citations

Sex steroid levels in developing and adult male and female zebra finches (Poephila guttata)

1990 • 237 citations

Aromatase Immunoreactivity in Axon Terminals of the Vertebrate Brain

1996 • 235 citations

Rapid Action of 17β-Estradiol on Kainate-Induced Currents in Hippocampal Neurons Lacking Intracellular Estrogen Receptors*

1999 • 233 citations

Estrogen Modulation of G-protein-coupled Receptors

1999 • 220 citations

Estrogen Receptor (ER)α and ERβ Exhibit Unique Pharmacologic Properties When Coupled to Activation of the Mitogen-Activated Protein Kinase Pathway*

2001 • 219 citations

Estrogen action and cytoplasmic signaling pathways. Part II: the role of growth factors and phosphorylation in estrogen signaling

2002 • 219 citations

Estrogen synthesis in the male brain triggers development of the avian song control pathway in vitro

2001 • 218 citations

Intratumoral Aromatase in Human Breast, Endometrial, and Ovarian Malignancies*

1998 • 215 citations

Social modulation of androgen levels in male teleost fish

2002 • 215 citations

Distribution of aromatase, estrogen receptor, and androgen receptor mRNA in the forebrain of songbirds and nonsongbirds

1999 • 215 citations

Estrogens in the Nervous System: Mechanisms and Nonreproductive Functions

2004 • 214 citations

Watching fights raises fish hormone levels

2001 • 211 citations

Estrogen receptor beta mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo.

2003 • 210 citations

Brain is the major site of estrogen synthesis in a male songbird.

1991 • 210 citations

Intrahypothalamic Implants of Testosterone or Estradiol and Resumption of Masculine Sexual Behavior in Long-term Castrated Male Rats

1974 • 206 citations

Androgens regulate aromatase cytochrome P450 messenger ribonucleic acid in rat brain.

1994 • 202 citations

Estradiol and testosterone in specific regions of the human female brain in different endocrine states

1995 • 202 citations

A Membrane Estrogen Receptor Mediates Intracellular Calcium Release in Astrocytes

2004 • 198 citations

Critical in Vivo Roles for Classical Estrogen Receptors in Rapid Estrogen Actions on Intracellular Signaling in Mouse Brain

2004 • 197 citations

Modulation of G Protein-Coupled Receptors by an Estrogen Receptor that Activates Protein Kinase A

1997 • 197 citations

Acute Stimulatory Effect of Estradiol on Striatal Dopamine Synthesis

1995 • 197 citations

Endogenous Sex Hormones in Relation to Age, Sex, Lifestyle Factors, and Chronic Diseases in a General Population: The Tromsø Study

2004 • 196 citations

5 alpha-reduced androgens play a key role in murine parturition.

1996 • 194 citations

Sexual differentiation: Basic and clinical aspects

1984 • 194 citations

Appetitive and Consummatory Male Sexual Behavior in Japanese Quail Are Differentially Regulated by Subregions of the Preoptic Medial Nucleus

1998 • 193 citations

Social Modulation of Circulating Hormone Levels in the Male

1981 • 192 citations

Neurosteroid Biosynthesis in the Human Brain and Its Clinical Implications

2003 • 190 citations

Testosterone-induced brain aromatase is sexually dimorphic

1986 • 189 citations

Strange Females Increase Plasma Testosterone Levels in Male Mice

1975 • 186 citations

Aromatase: Biologic Relevance of Tissue-Specific Expression

2004 • 184 citations

Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes

2002 • 181 citations

Brain aromatase and the control of male sexual behavior

1993 • 180 citations

Hormones, Sex, and Status in Women

1995 • 177 citations

Acute and chronic effects of an aromatase inhibitor on territorial aggression in breeding and nonbreeding male song sparrows

2000 • 176 citations

The membrane actions of estrogens can potentiate their lordosis behavior-facilitating genomic actions

2004 • 172 citations

Endocrine and behavioral responses to aggression and social dominance in the green anole lizard, Anolis carolinensis

1990 • 171 citations

Endocrine Defects in Mice Carrying a Null Mutation for the Progesterone Receptor Gene*

1997 • 169 citations

Altered Structure and Function of Reproductive Organs in Transgenic Male Mice Overexpressing Human Aromatase*

2001 • 169 citations

Sex differences in plasma concentrations of steroids during the sensitive period for brain differentiation in the zebra finch

1984 • 168 citations

Sexual differences in the Japanese quail: Behavior, morphology, and intracellular metabolism of testosterone

1983 • 168 citations

The Relationship between Libido and Testosterone Levels in Aging Men

2006 • 168 citations

Differential sensitivity of preoptic-septal neurons to microelectrophoressed estrogen during the estrous cycle

1976 • 167 citations

Behavioral Endocrinology

2001 • 167 citations

Aromatization mediates aggressive behavior in quail

1990 • 167 citations

Further evidence that androgen aromatization is essential for the activation of copulation in male quail

1980 • 165 citations

Systemic Distribution of Steroid Sulfatase and Estrogen Sulfotransferase in Human Adult and Fetal Tissues

2002 • 165 citations

The influence of estrous cycle and intrastriatal estradiol on sensorimotor performance in the female rat

1987 • 165 citations

Estrogen Receptor β Mediates Rapid Estrogen Actions on Gonadotropin-Releasing Hormone NeuronsIn Vivo

2003 • 163 citations

Mammalian Seasonal Rhythms: Behavior and Neuroendocrine Substrates

2016 • 162 citations

Hormonal Regulation of CREB Phosphorylation in the Anteroventral Periventricular Nucleus

1996 • 161 citations

Rapid Control of Brain Aromatase Activity by Glutamatergic Inputs

2005 • 161 citations

The Estrogen Trinity: Membrane, Cytosolic, and Nuclear Effects

2001 • 160 citations

Rapid, Hierarchical Modulation of Vocal Patterning by Steroid Hormones

2004 • 159 citations

Early membrane estrogenic effects required for full expression of slower genomic actions in a nerve cell line

2001 • 159 citations

Blockade of Testosterone-Induced Mounting Behavior in the Male Rat with Intracranial Application of the Aromatization Inhibitor, Androst-l,4,6-triene-3,17-dione

1975 • 158 citations

Estrogen Activation of Cyclic Adenosine 5′-Monophosphate Response Element-Mediated Transcription Requires the Extracellularly Regulated Kinase/Mitogen-Activated Protein Kinase Pathway

2003 • 158 citations

Calcium‐dependent phosphorylation processes control brain aromatase in quail

2003 • 157 citations

Single unit recording in hypothalamus and preoptic area of estrogen-treated and untreated ovariectomized female rats

1976 • 156 citations

Aromatase is pre-synaptic and sexually dimorphic in the adult zebra finch brain

2005 • 156 citations

Estrogen: nontranscriptional signaling pathway.

1997 • 156 citations

Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons

1992 • 154 citations

Progesterone Receptor Function from a Behavioral Perspective

1997 • 154 citations

Hormonal differentiation of sexual behavior in Japanese quail

1978 • 154 citations

Androgen increases formation of behaviourally effective oestrogen in dove brain

1981 • 154 citations

Testosterone and “5α-Dihydrotestosterone” Levels in Peripheral Plasma of Male and Female Ring Doves (Streptopelia risoria) During the Reproductive Cycle1

1977 • 149 citations

Novel Exon 1 of the Aromatase Gene Specific for Aromatase Transcripts in Human Brain

1994 • 149 citations

Steroid potentiation and inhibition of N-methyl-D-aspartate receptor-mediated intracellular Ca++ responses: structure-activity studies.

1994 • 148 citations

Localization of Aromatase in Synaptosomal and Microsomal Subfractions of Quail (<i>Coturnix coturnix japonic</i><i>a</i>) Brain

1989 • 147 citations

Fetal Death in Mice Lacking 5α-Reductase Type 1 Caused by Estrogen Excess

1997 • 147 citations

Critical re-examination of the distribution of aromatase-immunoreactive cells in the quail forebrain using antibodies raised against human placental aromatase and against the recombinant quail, mouse or human enzyme

1995 • 147 citations

Effects of Exposure to Vaginal Odor and Receptive Females on Plasma Testosterone in the Male Hamster

1974 • 146 citations

Androgen and estrogen action in the preoptic area and activation of copulatory behavior in quail

1990 • 145 citations

Alterations in plasma concentrations of testosterone, LH, and prolactin associated with mating in the male rat

1975 • 144 citations

Restoration of male sexual behavior by adult exogenous estrogens in male aromatase knockout mice

2004 • 142 citations

Estradiol inhibits atp-induced intracellular calcium concentration increase in dorsal root ganglia neurons

2003 • 141 citations

Membrane Sex-Steroid Receptors in the Brain

1996 • 137 citations

Aromatase Expression by Reactive Astroglia Is Neuroprotective

2003 • 137 citations

The C Terminus of the Human Nicotinic α4β2 Receptor Forms a Binding Site Required for Potentiation by an Estrogenic Steroid

2001 • 136 citations

17β-Estradiol depolarization of hypothalamic neurons is mediated by cyclic AMP

1990 • 135 citations

The “male effect” in sheep and goats: a review of the respective roles of the two olfactory systems

2004 • 134 citations

Direct and indirect effects of estrogen on rat hippocampus

2005 • 133 citations

The Influence of Mating and Related Stimuli on Plasma Levels of Luteinizing Hormone, Follicle Stimulating Hormone, Prolactin, and Testosterone in the Male Rat¹

1977 • 132 citations

Rapid Upregulation of Aromatase mRNA and Protein Following Neural Injury in the Zebra Finch (Taeniopygia guttata)

2001 • 132 citations

Prolonged ovarian sex steroid treatment of male rats produces antinociception: identification of sex-based divergent analgesic mechanisms

2000 • 130 citations

Rapid and Reversible Inhibition of Brain Aromatase Activity

2001 • 130 citations

Dehydroepiandrosterone Metabolism by 3β-Hydroxysteroid Dehydrogenase/Δ5-Δ4 Isomerase in Adult Zebra Finch Brain: Sex Difference and Rapid Effect of Stress

2003 • 130 citations

The induction by testosterone of aromatase activity in the preoptic area and activation of copulatory behavior

1990 • 130 citations

Radiotelemetric Monitoring of Hypothalamic Gonadotropin-Releasing Hormone Pulse Generator Activity Throughout the Menstrual Cycle of the Rhesus Monkey^*

1991 • 127 citations

Distribution of aromatase-immunoreactive cells in the forebrain of zebra finches (Taeniopygia guttata): Implications for the neural action of steroids and nuclear definition in the avian hypothalamus

1996 • 126 citations

Functional Antagonism of Gonadal Steroids at the 5-Hydroxytryptamine Type 3 Receptor

1998 • 125 citations

17β-Estradiol rapidly facilitates chemoinvestigation and mounting in castrated male rats

1999 • 120 citations

Estrogen-induced alterations of spinal cord enkephalin gene expression

1999 • 119 citations

Rapid Regulation of Pain by Estrogens Synthesized in Spinal Dorsal Horn Neurons

2004 • 116 citations

Overexpression of Aromatase Leads to Development of Testicular Leydig Cell Tumors

2000 • 116 citations

Rapid effects of estrogen on G protein-coupled receptor activation of potassium channels in the central nervous system (CNS)

2002 • 115 citations

Sex hormones regulate the contribution of PKCε and PKA signalling in inflammatory pain in the rat

2001 • 115 citations

Activation of Masculine Sexual Behavior by Intracranial Estradiol Benzoate Implants in Male Rats

1979 • 113 citations

Regulation of Aromatase Gene Expression in the Adult Rat Brain

1997 • 113 citations

Neuroendocrine Mechanisms Regulating Reproductive Cycles and Reproductive Behavior in Birds

2002 • 113 citations

Changes in firing rates of single preoptic and hypothalamic units following an intravenous administration of estrogen in the castrated female rat

1973 • 113 citations

Alteration in Sex-Specific Behaviors in Male Mice Lacking the Aromatase Gene

2003 • 111 citations

The Negative Feedback Control by Estradiol and Progesterone of LH Secretion in the Ovariectomized Rhesus Monkey12

1972 • 111 citations

Neurosteroids A New Regulatory Function in the Nervous System

2000 • 110 citations

The relation of serum 17-hydroxyprogesterone and estradiol-17β levels during the human menstrual cycle

1971 • 110 citations

A loss of aggressive behaviour and its reinstatement by oestrogen in mice lacking the aromatase gene (Cyp19)

2001 • 110 citations

Dopamine Activates Noradrenergic Receptors in the Preoptic Area

2002 • 108 citations

Selective Modulation of Genomic and Nongenomic Androgen Responses by Androgen Receptor Ligands

2003 • 107 citations

Rapid effects of aromatase inhibition on male reproductive behaviors in Japanese quail

2005 • 106 citations

Ecophysiological Studies of Hormone–Behavior Relations in Birds

2009 • 105 citations

Effect of some antiestrogens and aromatase inhibitors on androgen induced sexual behavior in castrated male rats

1976 • 104 citations

Testosterone implanted in the preoptic area of male Japanese quail must be aromatized to activate copulation

1989 • 104 citations

Multiple functions of aromatase and the active site structure; aromatase is the placental estrogen 2-hydroxylase

1993 • 104 citations

Diversity of ovarian steroid signaling in the hypothalamus

2005 • 104 citations

Rapid elevations in both steroid hormones and vocal signaling during playback challenge: a field experiment in Gulf toadfish

2005 • 103 citations

Steroid-specific regulation of agonistic responding in the anterior hypothalamus of male hamsters

1991 • 103 citations

Radial glia express aromatase in the injured zebra finch brain

2004 • 102 citations

Integration of steroid hormone initiated membrane action to genomic function in the brain

2005 • 101 citations

Novel mechanism for non‐genomic action of 17β‐oestradiol on kainate‐induced currents in isolated rat CA1 hippocampal neurones

1998 • 101 citations

Activation of sexual behavior by implantation of testosterone propionate and estradiol benzoate into the preoptic area of the male Japanese quail (Coturnix japonica)

1989 • 101 citations

Determinants of social proximity in Japanese quail (Coturnix coturnix japonica): Male behavior.

1986 • 101 citations

Appetitive as well as consummatory aspects of male sexual behavior in quail are activated by androgens and estrogens.

1995 • 100 citations

Acute changes in plasma testosterone levels and their relation to measures of sexual behaviour in the male house mouse (Mus musculus)

1978 • 100 citations

Aromatase Activity in Quail Brain: Correlation with Aggressiveness*

1989 • 97 citations

From social behavior to neural circuitry: Steroid hormones rapidly modulate advertisement calling via a vocal pattern generator

2006 • 96 citations

Estradiol rapidly activates male sexual behavior and affects brain monoamine levels in the quail brain

2005 • 96 citations

Neuroendocrine response to female ovulatory odors depends upon social condition in male common marmosets, Callithrix jacchus

2004 • 95 citations

Effects of castration and testosterone treatment on the activity of testosterone‐metabolizing enzymes in the brain of male and female zebra finches

1990 • 94 citations

Reflex Release of Gonadotropin and Increased Plasma Testosterone Concentration in Male Rabbits During Copulation

1968 • 93 citations

Biochemistry and Reproductive Endocrinology of Estrogen Sulfotransferase

2001 • 92 citations

Hormone Changes Triggered by Aggression in a Natural Population of Blackbirds

1979 • 92 citations

Acute and long-term effects of 17β-estradiol on Gi/o coupled neurotransmitter receptor function in the female rat brain as assessed by agonist-stimulated [35S]GTPγS binding

2000 • 91 citations

Rapid Decreases in Preoptic Aromatase Activity and Brain Monoamine Concentrations after Engaging in Male Sexual Behavior

2005 • 91 citations

Preoptic Glutamate Facilitates Male Sexual Behavior

2006 • 90 citations

Social Signals Influence Hormones Independently of Calling Behavior in the Treefrog (Hyla cinerea)

2000 • 90 citations

Multiple mechanisms control brain aromatase activity at the genomic and non-genomic level

2003 • 89 citations

SHORT-TERM EFFECTS OF COPULATION, HUMAN CHORIONIC GONADOTROPHIN INJECTION AND NON-TACTILE ASSOCIATION WITH A FEMALE ON TESTOSTERONE LEVELS IN THE MALE RAT

1974 • 88 citations

The Foam Production System of the Male Japanese Quail: Characterization of Structure and Function

1998 • 88 citations

Effects of the nonsteroidal inhibitor R76713 on testosterone-induced sexual behavior in the Japanese quail (Coturnix coturnix japonica)

1990 • 87 citations

Intracerebral Infusion of an Aromatase Inhibitor, Sexual Behavior and Brain Estrogen Receptor-Like Immunoreactivity in Intact Male Rats

1995 • 86 citations

A comparison of aromatase, 5α‐, and 5β‐ reductase activities in the brain and pituitary of male and female quail (C. c. japonica)

1987 • 85 citations

Partial purification and biochemical characterization of a membrane glucocorticoid receptor from an amphibian brain

2000 • 84 citations

Effect of the presence of females on the pituitary-testicular activity in male Japanese quail (Coturnix coturnix japonica)

1984 • 84 citations

Membrane Receptors for Corticosterone: A Mechanism for Rapid Behavioral Responses in an Amphibian

1994 • 80 citations

Evidence for a non-genomic action of progestins on sexual receptivity in hamster ventral tegmental area but not hypothalamus

1992 • 80 citations

Cytochrome P450 aromatase (CYP19) in the non-human primate brain: distribution, regulation, and functional significance

2001 • 79 citations

Cloning of the zebra finch androgen synthetic enzyme CYP17: A study of its neural expression throughout posthatch development

2003 • 79 citations

Estrogen receptor-α mediates estradiol attenuation of ATP-induced Ca2+ signaling in mouse dorsal root ganglion neurons

2005 • 78 citations

Glucocorticoids, Stress, and Behavior: Shifting the Timeframe1

1998 • 77 citations

Serum levels of sex hormones and corticosterone throughout 4- and 5-day estrous cycles in Fischer 344 rats and their simulation in ovariectomized females

2003 • 77 citations

Social interactions and androgen levels in birds

1981 • 76 citations

Short-term responses of plasma norepinephrine, epinephrine, glucocorticoid and testosterone titers to social and non-social stressors in male guinea pigs of different social status

1987 • 74 citations

A rapid neuromodulatory role for steroid hormones in the control of reproductive behavior

2006 • 74 citations

Rho/Rho Kinase as a Potential Target for the Treatment of Renal Disease

2005 • 73 citations

Neurosteroids: A New Regulatory Function in the Nervous System

1999 • 72 citations

Hormonal Activation of the Striatum and the Nucleus Accumbens Modulates Paced Mating Behavior in the Female Rat

1997 • 72 citations

Sex differences in androgen-regulated expression of cytochrome P450 aromatase in the rat brain

1997 • 71 citations

Testosterone Regulates Aromatase Activity in Discrete Brain Areas of Male Rhesus Macaques1

1989 • 71 citations

Changes in sexual behavior as a function of plasma sex steroid levels in post-menopausal women

1985 • 71 citations

Interaction of androgens and estrogens in the control of sexual behavior in male Japanese quail

1985 • 71 citations

PLASMA LEVELS OF TESTOSTERONE IN MALE RABBITS FOLLOWING COPULATION

1969 • 70 citations

EFFECTS OF SOCIAL ISOLATION AND OF FEMALE ODOURS ON THE REPRODUCTIVE SYSTEM, KIDNEYS AND ADRENALS OF UNMATED MALE RATS

1966 • 69 citations

Release of Luteinizing Hormone in Male Mice During Exposure to Females: Habituation of the Response

1979 • 68 citations

Endocrine Control of Female Mouse Odors that Elicit Luteinizing Hormone Surges and Attraction in Males

1982 • 65 citations

Genomic and Non-genomic Actions of Progesterone in the Control of Female Hamster Sexual Behavior

1994 • 65 citations

Rapid Effect of Testosterone on Striated Muscle Activity in Rats

1988 • 63 citations

Localization and controls of aromatase in the quail spinal cord

2000 • 61 citations

Relation of Circulating Estradiol and Progesterone to Gonadotropin Secretion and Estrous Cyclicity in Aging Female Rats*

1985 • 60 citations

Rapid Membrane Effects of Estrogen in the Central Nervous System

2002 • 59 citations

Seasonal Variation of Estradiol, Follicle Stimulating Hormone, and Dehydroepiandrosterone Sulfate in Women and Men

2006 • 59 citations

Ecophysiological Studies of Hormone-Behavior Relations in Birds

2002 • 58 citations

Differential Effect of 5α-Reductase Inhibition and Castration on Androgen-Regulated Gene Expression in Rat Prostate

1991 • 57 citations

Androgen biosynthesis in the quail brain

2002 • 57 citations

Neuroanatomical distribution of aromatase mRNA in the rat brain: indications of regional regulation

1997 • 57 citations

Sexual partner preference, hypothalamic morphology and aromatase in rams

2004 • 56 citations

Facilitation of sexual receptivity in hamsters by simultaneous progesterone implants into the VMH and ventral mesencephalon

1990 • 55 citations

Testosterone metabolism and testosterone-dependent characteristics in Japanese quail

1984 • 55 citations

Responses of antidromically identified preoptic neurons in the rat to neurotransmitters and to estrogen

1974 • 54 citations

Presynaptic N‐methyl‐D‐aspartate receptor expression is increased by estrogen in an aromatase‐rich area of the songbird hippocampus

2004 • 54 citations

The control of preoptic aromatase activity by afferent inputs in Japanese quail

2001 • 53 citations

Sexual dimorphism in the social proximity behavior of Japanese quail (Coturnix coturnix japonica).

1986 • 52 citations

Overexpression of aromatase leads to hyperplasia and changes in the expression of genes involved in apoptosis, cell cycle, growth, and tumor suppressor functions in the mammary glands of transgenic mice.

2001 • 52 citations

Endocrine Changes Associated with Spawning Behavior in Male Kokanee Salmon (Oncorhynchus nerka) and the Effects of Anosmia

1993 • 50 citations

Estradiol (E2) Elicits Src Phosphorylation in the Mouse Neocortex: The Initial Event in E2 Activation of the MAPK Cascade?

2001 • 49 citations

Endocrine changes in male stumptailed macaques (Macaca arctoides) as a response to odor stimulation with vaginal secretions

2005 • 47 citations

Acute estrogen potentiates excitatory responses of neurons in rat hypothalamic ventromedial nucleus

2005 • 47 citations

A Subset of Kappa Opioid Ligands Bind to the Membrane Glucocorticoid Receptor in an Amphibian Brain

2000 • 47 citations

Sex hormones and pain: A new role for brain aromatase?

2000 • 46 citations

Influence of Continuous Illumination on Estrous Cycle of Rats: Time Course of Changes in Levels of Gonadotropins and Ovarian Steroids until Occurrence of Persistent Estrus

1984 • 46 citations

Short-latency effect of testosterone on copulatory behaviour and ejaculation in sexually experienced intact male rats

1977 • 45 citations

Androgen Metabolism in the Prostate of the Finasteride-Treated, Adult Rat: A Possible Explanation for the Differential Action of Testosterone and 5α-Dihydrotestosterone during Development of the Male Urogenital Tract¹

1997 • 45 citations

Anatomical relationships between aromatase and tyrosine hydroxylase in the quail brain: Double-label immunocytochemical studies

1998 • 43 citations

Overexpression of aromatase in transgenic male mice results in the induction of gynecomastia and other biochemical changes in mammary glands

2001 • 43 citations

Uncoupling of 5-HT1A receptors in the brain by estrogens: regional variations in antagonism by ICI 182,780

2003 • 43 citations

Steroid 5α-reductase isozymes in the adult female rat brain: central role of dihydrotestosterone

2006 • 42 citations

Estradiol application to one striatum produces postural deviation to systemic apomorphine

1984 • 42 citations

Diurnal variations of sexual receptivity in the female Japanese quail (Coturnix coturnix japonica)

1986 • 40 citations

Aromatization of androgens into estrogens reduces response latency to a noxious thermal stimulus in male quail

2004 • 39 citations

The influence of estradiol on nervous system function

2005 • 39 citations

Distribution and regulation of estrogen-2-hydroxylase in the quail brain

1994 • 38 citations

Sexual receptivity is reduced in the female mu-opioid receptor knockout mouse

2005 • 38 citations

The cynomolgus monkey (Macaca fascicularis) is the best animal model for the study of steroid glucuronidation

2003 • 37 citations

Aggressive behavior in birds: An experimental model for studies of brain-steroid inteactions

1990 • 36 citations

The Selective Interaction of Neurosteroids with the GABAA Receptor

1999 • 35 citations

Hormonal Correlates of Gonadal Regression and Spontaneous Recovery in Japanese Quail Exposed to Short Day-Lengths

1985 • 34 citations

Estrogen-2-hydroxylase in the brain of the male African catfish, Clarias gariepinus

1988 • 34 citations

Rapid Uncoupling of Serotonin-1A Receptors in Rat Hippocampus by 17β-Estradiol in vitro Requires Protein Kinases A and C

2002 • 34 citations

Homogeneity of intracellular electrophysiological properties in different neuronal subtypes in medial preoptic slices containing the sexually dimorphic nucleus of the rat

1994 • 34 citations

Immunocytochemical localization of aromatase in sensory and integrating nuclei of the hindbrain in Japanese quail (Coturnix japonica)

2004 • 32 citations

Electrophysiological and neurochemical characterization of neurons of the medial preoptic area in Japanese quail (Coturnix japonica)

2004 • 32 citations

Distribution of Uridine Diphosphate-Glucuronosyltransferase (UGT) Expression and Activity in Cynomolgus Monkey Tissues: Evidence for Differential Expression of Steroid-Conjugating UGT Enzymes in Steroid Target Tissues*

2000 • 31 citations

Social interactions and androgen levels in birds

1981 • 29 citations

Fluoxetine May Influence Lordosis of Rats through Effects on Midbrain 3α,5α‐THP Concentrations

2003 • 28 citations

Aspects of Copulatory Behavior Preventing Atrophy in Male Rats’ Reproductive System

1968 • 27 citations

Differences in aspects of personality and sexuality between perimenopausal women making different choices regarding prophylactic oophorectomy at elective hysterectomy

2005 • 25 citations

Ovine Fetal Estrogen Sulfotransferase in Brain Regions Important for Hypothalamus-Pituitary-Adrenal Axis Control

2000 • 25 citations

Effect of Coitus on Serum levels of Testosterone and LH in Male and Female Rabbits

1975 • 22 citations

The effect of female rat proximity on the reproductive system of male rats

1972 • 22 citations

PLASMA TESTOSTERONE IN COURTING AND INCUBATING MALE BARBARY DOVES (STREPTOPELIA RISORIA)

1975 • 18 citations

Effects of estrus, estrogen-progesterone priming, and vaginal stimulation on tonic immobility, dorsal immobility, and lordosis in the female rat

1985 • 18 citations

Effects of intrastriatal hormones on the dorsal immobility response in male rats

1990 • 13 citations

The role of the uterus in regulation of heat duration in cycling rats

1985 • 11 citations

A comparison of the effects of testosterone on aggressive responses by the domestic chick to the human hand and to a large sphere

1981 • 11 citations

The effects of intrastriatal hormones on the dorsal immobility response in gonadectomized male and female rats

1989 • 7 citations

Differential effects of intrastriatal estradiol on the dorsal immobility response in male rats

1992 • 6 citations