Identity of an Estrogen Membrane Receptor Coupled to a G Protein in Human Breast Cancer Cells

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

β-Arrestin-Dependent Formation of β ₂ Adrenergic Receptor-Src Protein Kinase Complexes

1999 • 1,427 citations

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF

2000 • 1,265 citations

Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells

1999 • 1,046 citations

Multiple actions of steroid hormones--a focus on rapid, nongenomic effects.

2000 • 980 citations

Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

1999 • 895 citations

Estrogen Action Via the G Protein-Coupled Receptor, GPR30: Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis

2002 • 840 citations

Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes

2003 • 787 citations

Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor

2003 • 697 citations

Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions

2001 • 681 citations

Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription.

1994 • 667 citations

Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model

2004 • 556 citations

Identification of a Gene (GPR30) with Homology to the G-Protein-Coupled Receptor Superfamily Associated with Estrogen Receptor Expression in Breast Cancer

1997 • 549 citations

Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription

1997 • 478 citations

Estrogen Receptor α Rapidly Activates the IGF-1 Receptor Pathway

2000 • 461 citations

Proximal Events in Signaling by Plasma Membrane Estrogen Receptors

2003 • 460 citations

Cancer and developmental exposure to endocrine disruptors.

2002 • 459 citations

Rapid Signaling of Estrogen in Hypothalamic Neurons Involves a Novel G-Protein-Coupled Estrogen Receptor that Activates Protein Kinase C

2003 • 455 citations

The G Protein-coupled Receptor GPR30 Mediates c-fos Up-regulation by 17β-Estradiol and Phytoestrogens in Breast Cancer Cells

2004 • 429 citations

Linkage of Rapid Estrogen Action to MAPK Activation by ERα-Shc Association and Shc Pathway Activation

2002 • 403 citations

Nongenomic Actions of Steroid Hormones in Reproductive Tissues*

1998 • 375 citations

Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor α and estrogen receptor β

2000 • 362 citations

Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor, GPR30: a novel signaling pathway with potential significance for breast cancer

2002 • 361 citations

Discovery of Three Novel G-Protein-Coupled Receptor Genes

1998 • 308 citations

Dehydroepiandrosterone Activates Endothelial Cell Nitric-oxide Synthase by a Specific Plasma Membrane Receptor Coupled to Gαi2,3

2002 • 285 citations

Rapid Action of 17β-Estradiol on Kainate-Induced Currents in Hippocampal Neurons Lacking Intracellular Estrogen Receptors*

1999 • 233 citations

Cloning of Human cDNA Encoding a Novel Heptahelix Receptor Expressed in Burkitt's Lymphoma and Widely Distributed in Brain and Peripheral Tissues

1996 • 212 citations

Cloning of cDNAs Encoding G Protein-Coupled Receptor Expressed in Human Endothelial Cells Exposed to Fluid Shear Stress

1997 • 209 citations

Expression and regulation of estrogen receptor beta in human breast tumors and cell lines.

2000 • 198 citations

Rapid actions of estrogens in GH3/B6 pituitary tumor cells via a plasma membrane version of estrogen receptor-α

1999 • 167 citations

Nongenomic Actions of Steroid Hormones in Reproductive Tissues

1998 • 164 citations

Effects of Estrogens and Xenoestrogens on Androgen Production by Atlantic Croaker Testes In Vitro: Evidence for a Nongenomic Action Mediated by an Estrogen Membrane Receptor1

2000 • 159 citations

Characterization of membrane receptor activity for 17α,20β,21-trihydroxy-4-pregnen-3-one in ovaries of spotted seatrout (Cynoscion nebulosus)

1990 • 139 citations

The Unusual Binding Properties of the Third Distinct Teleost Estrogen Receptor Subtype ERβa Are Accompanied by Highly Conserved Amino Acid Changes in the Ligand Binding Domain

2004 • 131 citations

Estradiol Signaling via Sequestrable Surface Receptors

2001 • 130 citations

Cloning of a Novel Member of the G Protein-Coupled Receptor Family Related to Peptide Receptors

1997 • 99 citations

Binding Characteristics of Estrogen Receptor (ER) in Atlantic Croaker (Micropogonias undulatus) Testis: Different Affinity for Estrogens and Xenobiotics from that of Hepatic ER1

1999 • 99 citations

Non-genomic progesterone receptors in the mammalian ovary: some unresolved issues

2003 • 92 citations

Characterization of membrane estrogen binding proteins from rabbit uterus

1999 • 74 citations

The plasma membrane estrogen receptor: nuclear or unclear?

2001 • 72 citations

Biochemical Characterization of a Membrane Androgen Receptor in the Ovary of the Atlantic Croaker (Micropogonias undulatus)1

2004 • 64 citations

G Protein coupling of CGS 21680 binding sites in the rat hippocampus and cortex is different from that of adenosine A1 and striatal A2A receptors

1999 • 61 citations

AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen

2000 • 61 citations

Estrogen receptors in human myeloma cells.

2000 • 60 citations

Gs Protein-coupled Receptor Agonists Induce Transactivation of the Epidermal Growth Factor Receptor in T84 Cells

2004 • 58 citations

17β-estradiol Inhibits the Production of RANTES in Human Keratinocytes

2003 • 56 citations

The membrane effects of 17β-estradiol on chondrocyte phenotypic expression are mediated by activation of protein kinase C through phospholipase C and G-proteins

2000 • 55 citations

Progestin upregulates G‐protein‐coupled receptor 30 in breast cancer cells

2002 • 51 citations

Pesticides Interfere with the Nongenomic Action of a Progestogen on Meiotic Maturation by Binding to its Plasma Membrane Receptor on Fish Oocytes

1999 • 47 citations

Carcinogenesis and Its Modification by Environmental Endocrine Disruptors: In Vivo Experimental and Epidemiological Findings

2003 • 25 citations

Tailoring adjuvant treatments for the individual breast cancer patient

2003 • 19 citations