Overexpression of aromatase in transgenic male mice results in the induction of gynecomastia and other biochemical changes in mammary glands

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1994 • 2,071 citations

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

1994 • 1,970 citations

Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene

1998 • 855 citations

Mouse Estrogen Receptor β Forms Estrogen Response Element-Binding Heterodimers with Estrogen Receptor α

1997 • 610 citations

Cell-cycle inhibitors: three families united by a common cause

2000 • 428 citations

Germ cells of the mouse testis express P450 aromatase.

1993 • 280 citations

In situ aromatization enhances breast tumor estradiol levels and cellular proliferation.

1998 • 213 citations

Differential expression of estrogen receptor-alpha and -beta messenger RNAs as a potential marker of ovarian carcinogenesis.

1998 • 209 citations

Mouse Estrogen Receptor Forms Estrogen Response Element-Binding Heterodimers with Estrogen Receptor

1997 • 203 citations

Aromatase and gynecomastia.

1999 • 170 citations

Estrogen receptor and progesterone receptor genes are expressed differentially in mouse embryos during preimplantation development.

1993 • 150 citations

Mammary gland growth and development from the postnatal period to postmenopause: ovarian steroid receptor ontogeny and regulation in the mouse.

1998 • 144 citations

Germ cells of the mouse testis express P450 aromatase

1993 • 143 citations

The Aromatase Excess Syndrome Is Associated with Feminization of Both Sexes and Autosomal Dominant Transmission of Aberrant P450 Aromatase Gene Transcription1

1998 • 142 citations

An Aromatase-Producing Sex-Cord Tumor Resulting in Prepubertal Gynecomastia

1991 • 126 citations

Estrogen and progestin regulation of cell cycle progression.

1998 • 117 citations

Overexpression of Aromatase Leads to Development of Testicular Leydig Cell Tumors

2000 • 116 citations

Overexpression of int-5/aromatase in mammary glands of transgenic mice results in the induction of hyperplasia and nuclear abnormalities.

1996 • 113 citations

The Aromatase Excess Syndrome Is Associated with Feminization of Both Sexes and Autosomal Dominant Transmission of Aberrant P450 Aromatase Gene Transcription

1998 • 108 citations

Hormonal Changes during Puberty: V. Transient Pubertal Gynecomastia: Abnormal Androgen-Estrogen Ratios*

1984 • 91 citations

Upregulation of basic fibroblast growth factor in breast carcinoma and its relationship to vascular density, oestrogen receptor, epidermal growth factor receptor and survival

1999 • 88 citations

Aromatase in the human testis

1993 • 85 citations

Molecular Basis of Severe Gynecomastia Associated with Aromatase Expression in a Fibrolamellar Hepatocellular Carcinoma¹

1998 • 61 citations

Hormonal factors in carcinogenesis of the prostate and testis in humans and in animal models.

1996 • 57 citations

Molecular Basis of Severe Gynecomastia Associated with Aromatase Expression in a Fibrolamellar Hepatocellular Carcinoma

1998 • 55 citations

Overexpression of aromatase leads to hyperplasia and changes in the expression of genes involved in apoptosis, cell cycle, growth, and tumor suppressor functions in the mammary glands of transgenic mice.

2001 • 52 citations

Testicular steroid biosynthesis in a boy with a large cell calcifying Sertoli cell tumor producing prepubertal gynecomastia

1995 • 41 citations

Thyroxine increases the levels of epidermal growth factor messenger ribonucleic acid (EGF mRNA) in the thyroid in vivo, as revealed by quantitative reverse transcription polymerase chain reaction with an internal control EGF mRNA.

1993 • 23 citations

Thyroxine increases the levels of epidermal growth factor messenger ribonucleic acid (EGF mRNA) in the thyroid in vivo, as revealed by quantitative reverse transcription polymerase chain reaction with an internal control EGF mRNA

1993 • 8 citations

Oestrogen secreting Leydig cell tumour and GnRH agonist in‐vivo and in‐vitro studies

1992 • 8 citations