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Rapid Uncoupling of Serotonin-1A Receptors in Rat Hippocampus by 17β-Estradiol in vitro Requires Protein Kinases A and C

Data up to Jan 2025

Published2002
Citations34
References42

Total Citations Per Year

Abstract

References (42)

Estrogen Actions in the Central Nervous System1

1999 • 1,381 citations

Estrogen Actions in the Central Nervous System

1999 • 641 citations

Comparative localization of serotonin1A, 1C, and 2 receptor subtype mRNAs in rat brain

1995 • 549 citations

Desensitization of G-protein-coupled Receptors

1999 • 510 citations

Novel Mechanisms of Estrogen Action in the Brain: New Players in an Old Story

1999 • 434 citations

Immunocytochemical localization of serotonin1A receptors in the rat central nervous system

1996 • 370 citations

Cellular localization of the 5-HT receptor in primate brain neurons and glial cells

1996 • 304 citations

Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-alpha knock-out mice.

2000 • 247 citations

Modulation by estradiol of serotonin receptors in brain

1982 • 237 citations

G protein-coupled receptors: heterologous regulation of homologous desensitization and its implications

1996 • 234 citations

The recombinant 5‐HT1A receptor: G protein coupling and signalling pathways

1999 • 232 citations

Rapid effects of estrogen to modulate G protein-coupled receptors via activation of protein kinase A and protein kinase C pathways

1999 • 229 citations

Estrogen Modulation of G-protein-coupled Receptors

1999 • 220 citations

Ultrastructural localization of 5-hydroxytryptamine1A receptors in the rat brain

1996 • 153 citations

Estrogen suppresses mu-opioid- and GABAB-mediated hyperpolarization of hypothalamic arcuate neurons

1992 • 139 citations

Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signalling

2000 • 136 citations

Nongenomic Actions of Estrogen in the Brain: Physiological Significance and Cellular Mechanisms

1996 • 129 citations

Protein kinase C induces phosphorylation and desensitization of the human 5-HT1A receptor

1991 • 115 citations

Roles of second-messenger systems and neuronal activity in the regulation of lordosis by neurotransmitters, neuropeptides, and estrogen: A review

1994 • 109 citations

Mapping of neural and signal transduction pathways for lordosis in the search for estrogen actions on the central nervous system

1998 • 108 citations

Acute 17β-estradiol treatment down-regulates serotonin 5HT1A receptor mRNA expression in the limbic system of female rats

1998 • 102 citations

Estrogen Rapidly Attenuates a GABA<sub>B</sub> Response in Hypothalamic Neurons

1996 • 97 citations

Acute and long-term effects of 17β-estradiol on Gi/o coupled neurotransmitter receptor function in the female rat brain as assessed by agonist-stimulated [35S]GTPγS binding

2000 • 91 citations

Estrogens Cause Rapid Activation of IP3-PKC-α Signal Transduction Pathway in HEPG2 Cells

1998 • 88 citations

μ-Opioid receptor down-regulation and cAMP-dependent protein kinase phosphorylation in a mouse model of chronic morphine tolerance

1998 • 86 citations

Estrogens Act in Rat Hippocampus and Frontal Cortex to Produce Rapid, Receptor-Mediated Decreases in Serotonin 5-HT<sub>1A</sub> Receptor Function

2001 • 70 citations

Estradiol Elevates Protein Kinase C Catalytic Activity in the Preoptic Area of Female Rats1

1998 • 70 citations

Extrapyramidal Symptoms during Long-Term Treatment with Antipsychotics Special Focus on Clozapine and D1 and D2 Dopamine Antagonists

1996 • 51 citations

Estradiol modulation of the hyperphagia induced by the 5-HT1A agonist, 8-OH-DPAT

1992 • 51 citations

Prior Treatment with Estrogen Attenuates the Effects of the 5-HT1AAgonist, 8-OH-DPAT, on Lordosis Behavior

1996 • 49 citations

Characterization of 5-HT1A receptor-mediated []GTPγS binding in rat hippocampal membranes

1998 • 49 citations

Production and characterization of polyclonal antibodies recognizing the intracytoplasmic third loop of the 5-hydroxytryptamine1A receptor

1994 • 39 citations

Expression of G Protein Subunits in the Aging Cardiovascular System

1995 • 35 citations

Activation of protein kinase C in the hypothalamic ventromedial nucleus or the midbrain central gray facilitates lordosis

1994 • 34 citations

Estradiol-17?-BSA stimulates Ca2+ uptake through nongenomic pathways in primary rabbit kidney proximal tubule cells: Involvement of cAMP and PKC

2000 • 33 citations

Protein Kinase A Induces Phosphorylation of the Human 5-HT1A Receptor and Augments Its Desensitization by Protein Kinase C in CHO-K1 Cells

1994 • 27 citations

μ-Opioid agonist-stimulated [35S]GTPγS binding in guinea pig hypothalamus: effects of estrogen

1998 • 25 citations

Expression and modulation of 5-hydroxytryptamine1A receptors in P11 cells.

1996 • 21 citations

Inhibition of protein phosphatases alters the expression of morphine tolerance in mice

1998 • 14 citations

Ultrastructural localization of 5‐hydroxytryptamine1A receptors in the rat brain

1996 • 10 citations

Role of local environmental factors in determining tissue-specific effects of estrogen: Examination of uterine tissues transplanted to brain

1992 • 3 citations

A method for the determination of activated receptor phosphorylation state following in vivo drug treatment

1999 • 2 citations

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