Characterization of Endocrine Gland-derived Vascular Endothelial Growth Factor Signaling in Adrenal Cortex Capillary Endothelial Cells

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Mechanisms of angiogenesis and arteriogenesis

2000 • 4,120 citations

Vascular-specific growth factors and blood vessel formation

2000 • 3,667 citations

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1999 • 3,529 citations

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

1998 • 2,440 citations

Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway

1998 • 1,963 citations

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

1998 • 1,587 citations

Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.

1998 • 1,191 citations

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells.

1997 • 1,162 citations

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase).

1991 • 1,041 citations

Clinical applications of angiogenic growth factors and their inhibitors

1999 • 1,017 citations

G-protein-coupled receptors and signaling networks: emerging paradigms

2001 • 1,005 citations

Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells

1998 • 996 citations

Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis.

1997 • 924 citations

The Pathways Connecting G Protein-coupled Receptors to the Nucleus through Divergent Mitogen-activated Protein Kinase Cascades

1998 • 819 citations

Role of vascular endothelial growth factor in the regulation of angiogenesis

1999 • 733 citations

Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: A study using quail-chick transplantation chimeras

1981 • 681 citations

Signal characteristics of G protein-transactivated EGF receptor

1997 • 669 citations

Vascular endothelial growth factor is essential for corpus luteum angiogenesis

1998 • 641 citations

Analysis of Biological Effects and Signaling Properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2)

2001 • 625 citations

Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

1996 • 555 citations

Identification of an angiogenic mitogen selective for endocrine gland endothelium

2001 • 549 citations

Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

1995 • 541 citations

The Akt kinase signals directly to endothelial nitric oxide synthase

1999 • 469 citations

Neuropilin-1 Mediates Collapsin-1/Semaphorin III Inhibition of Endothelial Cell Motility

1999 • 469 citations

Nitric Oxide Is an Upstream Signal of Vascular Endothelial Growth Factor-induced Extracellular Signal-regulated Kinase½ Activation in Postcapillary Endothelium

1998 • 436 citations

The Vascular Endothelial Growth Factor Receptor KDR Activates Multiple Signal Transduction Pathways in Porcine Aortic Endothelial Cells

1997 • 436 citations

Mitogenic Signaling via G Protein-Coupled Receptors

1996 • 425 citations

Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts.

1993 • 377 citations

Vascular System Defects and Impaired Cell Chemokinesis as a Result of Gα ₁₃ Deficiency

1997 • 340 citations

Identification of Two Prokineticin cDNAs: Recombinant Proteins Potently Contract Gastrointestinal Smooth Muscle

2001 • 270 citations

Vascular Bed–specific Expression of an Endothelial Cell Gene Is Programmed by the Tissue Microenvironment

1997 • 269 citations

Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment.

1996 • 235 citations

cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation

1997 • 200 citations

Bv8, a small protein from frog skin and its homologue from snake venom induce hyperalgesia in rats

1999 • 186 citations

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration

2000 • 181 citations

Thrombin Induces the Activation of Progelatinase A in Vascular Endothelial Cells

1995 • 177 citations

Tyrosine kinase pathways and the regulation of smooth muscle contractility

1994 • 168 citations

Regulation of endothelial cell gap formation and paracellular permeability.

1995 • 165 citations

Insulin and Insulin-like Growth Factor I Receptors Utilize Different G Protein Signaling Components

2001 • 161 citations

Sphingosine 1-phosphate receptors

2001 • 139 citations

Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway

1994 • 98 citations

MIT₁, a black mamba toxin with a new and highly potent activity on intestinal contraction

1999 • 94 citations

The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes

1999 • 89 citations

The mammalian homologue of the novel peptide Bv8 is expressed in the central nervous system and supports neuronal survival by activating the MAP kinase/PI‐3‐kinase pathways

2001 • 84 citations

A structural homologue of colipase in black mamba venom revealed by NMR floating disulphide bridge analysis

1998 • 75 citations

Snake Venom. The Amino Acid Sequence of Protein A fromDendroaspis polylepis polylepis(Black mamba) Venom

1980 • 56 citations

Heterologous desensitization of response mediated by selective PKC-dependent phosphorylation of G_i-1and G_i-2

2000 • 53 citations

Outward K+ current in epithelial cells isolated from intermediate portion of endolymphatic sac of guinea pigs

1996 • 52 citations

Substantially attenuated hemodynamic responses to Escherichia coli-derived vascular endothelial growth factor given by intravenous infusion compared with bolus injection.

1998 • 45 citations