Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase).

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1989 • 1,237 citations

Protein sequencing by tandem mass spectrometry.

1986 • 1,165 citations

[17] Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis

1983 • 1,115 citations

Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

1990 • 1,087 citations

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II

1988 • 1,032 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

An Insulin-Stimulated Protein Kinase Similar to Yeast Kinases Involved in Cell Cycle Control

1990 • 701 citations

Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro.

1987 • 604 citations

Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis

1989 • 453 citations

Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase.

1989 • 442 citations

Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo.

1988 • 404 citations

Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells.

1990 • 336 citations

A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae

1989 • 298 citations

Control of glycogen synthase by hierarchal protein phosphorylation

1990 • 266 citations

Characterization of insulin-stimulated microtubule-associated protein kinase. Rapid isolation and stabilization of a novel serine/threonine kinase from 3T3-L1 cells.

1988 • 257 citations

Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase.

1990 • 245 citations

Evidence for an epidermal growth factor-stimulated protein kinase cascade in Swiss 3T3 cells. Activation of serine peptide kinase activity by myelin basic protein kinases in vitro.

1990 • 175 citations

Tandem quadrupole Fourier-transform mass spectrometry of oligopeptides and small proteins.

1987 • 152 citations

A 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in fibroblasts.

1990 • 142 citations

Purification and characterization of a maturation-activated myelin basic protein kinase from sea star oocytes.

1990 • 141 citations

Synergistic Phosphorylation of Rabbit Muscle Glycogen Synthase by Cyclic AMP-dependent Protein Kinase and Casein Kinase I

1989 • 133 citations

Spk1, a New Kinase from Saccharomyces cerevisiae, Phosphorylates Proteins on Serine, Threonine, and Tyrosine

1991 • 130 citations

Defective regulation of mitogen-activated protein kinase activity in a 3T3 cell variant mitogenically nonresponsive to tetradecanoyl phorbol acetate.

1991 • 92 citations

An insulin-stimulated ribosomal protein S6 kinase from rabbit liver

1989 • 84 citations

Current research in protein chemistry : techniques, structure, and function

1990 • 67 citations

The amino acid sequence of the sex steroid-binding protein of rabbit serum

1989 • 50 citations

Evidence for insulin-dependent activation of S6 and microtubule-associated protein-2 kinases via a human insulin receptor/v-ros hybrid.

1990 • 41 citations

Defective Regulation of Mitogen-Activated Protein Kinase Activity in a 3T3 Cell Variant Mitogenically Nonresponsive to Tetradecanoyl Phorbol Acetate

1991 • 26 citations

Comparative peptide mapping at the nanomole level

1981 • 18 citations

Molecular Analyses of Gene Products Associated with the Response of Cells to Mitogenic Stimulation

1988 • 9 citations

Absence of protein kinase C in nuclei of EL4 mouse thymoma cells.

1987 • 9 citations