Xenopus Kielin: A dorsalizing factor containing multiple chordin-type repeats secreted from the embryonic midline

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1996 • 3,041 citations

Sonic hedgehog mediates the polarizing activity of the ZPA

1993 • 2,313 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4

1996 • 1,604 citations

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1992 • 1,176 citations

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

1996 • 1,126 citations

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

1994 • 1,114 citations

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

1993 • 1,086 citations

HNF-3β is essential for node and notochord formation in mouse development

1994 • 985 citations

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 • 869 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation

1996 • 789 citations

The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

1994 • 786 citations

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

1994 • 759 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

A new secreted protein that binds to Wnt proteins and inhibits their activites

1999 • 706 citations

Zebrafish organizer development and germ-layer formation require nodal-related signals

1998 • 657 citations

Patterning of mammalian somites by surface ectoderm and notochord: Evidence for sclerotome induction by a hedgehog homolog

1994 • 594 citations

Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate

1993 • 470 citations

Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling

1998 • 458 citations

Ectodermal Patterning in Vertebrate Embryos

1997 • 457 citations

Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites

1994 • 451 citations

Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus.

1993 • 449 citations

The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system

1991 • 432 citations

Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation

1995 • 415 citations

The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4

1997 • 382 citations

cyclops encodes a nodal-related factor involved in midline signaling

1998 • 360 citations

Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish

1998 • 355 citations

Vertebrate Embryonic Cells Will Become Nerve Cells Unless Told Otherwise

1997 • 348 citations

Thrombospondins: structure and regulation of expression

1992 • 345 citations

Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis

1992 • 332 citations

The early development of Xenopus laevisby P. Hausen and M. Riebesell, Springer-Verlag, 1991. £78.50 (vii + 142 pages) ISBN 3 540 53740 6

1993 • 323 citations

Tail formation as a continuation of gastrulation: the multiple cell populations of the Xenopus tailbud derive from the late blastopore lip

1993 • 314 citations

HNF-3β as a regulator of floor plate development

1994 • 287 citations

Zebrafish Nodal-Related Genes Are Implicated in Axial Patterning and Establishing Left–Right Asymmetry

1998 • 279 citations

BMP-binding modules in chordin: a model for signalling regulation in the extracellular space

2000 • 244 citations

A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain.

1992 • 236 citations

Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene.

1993 • 234 citations

Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis

1995 • 200 citations

Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation

1995 • 165 citations

Xnr4:AXenopusNodal-Related Gene Expressed in the Spemann Organizer

1997 • 159 citations

Region-Specific Neural Induction of an engrailed Protein by Anterior Notochord in Xenopus

1990 • 145 citations

The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA.

1995 • 137 citations

Selection for genes encoding secreted proteins and receptors.

1996 • 135 citations

Von Willebrand factor shares a distinctive cysteine-rich domain with thrombospondin and procollagen

1987 • 57 citations

Overexpression of the Homeobox GeneXnot-2Leads to Notochord Formation inXenopus

1996 • 49 citations

Role of sonic hedgehog in branchiomotor neuron induction in zebrafish

1998 • 30 citations

Patterning by genes expressed in Spemann's organizer.

1997 • 28 citations