BMP-binding modules in chordin: a model for signalling regulation in the extracellular space

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

1996 • 1,126 citations

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

1994 • 1,114 citations

Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein

1995 • 1,028 citations

FORMATION AND FUNCTION OF SPEMANN'S ORGANIZER

1997 • 836 citations

A common plan for dorsoventral patterning in Bilateria

1996 • 774 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

The organizer factors Chordin and Noggin are required for mouse forebrain development

2000 • 528 citations

The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning

1997 • 518 citations

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin

1995 • 436 citations

Cleavage of Chordin by Xolloid Metalloprotease Suggests a Role for Proteolytic Processing in the Regulation of Spemann Organizer Activity

1997 • 398 citations

Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins

1997 • 350 citations

Thrombospondins: structure and regulation of expression

1992 • 345 citations

Alternatively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: differential expression of the amino-propeptide.

1991 • 340 citations

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene.

1994 • 307 citations

Peroxidasin: a novel enzyme-matrix protein of Drosophila development.

1994 • 285 citations

Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo.

1993 • 283 citations

Differential expression of a cysteine-rich domain in the amino-terminal propeptide of type II (cartilage) procollagen by alternative splicing of mRNA.

1990 • 271 citations

Expression of the mouse α1 (II) collagen gene is not restricted to cartilage during development

1991 • 264 citations

Mammalian BMP-1/Tolloid-Related Metalloproteinases, Including Novel Family Member Mammalian Tolloid-Like 2, Have Differential Enzymatic Activities and Distributions of Expression Relevant to Patterning and Skeletogenesis

1999 • 264 citations

Type IIA Procollagen Containing the Cysteine-rich Amino Propeptide Is Deposited in the Extracellular Matrix of Prechondrogenic Tissue and Binds to TGF-β1 and BMP-2

1999 • 263 citations

The Xenopus Dorsalizing Factor noggin Ventralizes Drosophila Embryos by Preventing DPP from Activating Its Receptor

1996 • 242 citations

Collagen II Is Essential for the Removal of the Notochord and the Formation of Intervertebral Discs

1998 • 240 citations

Expression of a type II collagen gene in the zebrafish embryonic axis

1995 • 227 citations

Localized enhancement and repression of the activity of the TGF-P family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo

1992 • 222 citations

Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor.

1996 • 213 citations

Mutations affecting development of the notochord in zebrafish

1996 • 194 citations

Alternative splice form of type II procollagen mRNA (IIA) is predominant in skeletal precursors and non‐cartilaginous tissues during early mouse development

1994 • 192 citations

Local inhibition and long-range enhancement of Dpp signal transduction by Sog

1999 • 185 citations

The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm.

1996 • 178 citations

Cloning and Characterization of Two Novel Human cDNAs (NELL1 and NELL2) Encoding Proteins with Six EGF-like Repeats

1996 • 128 citations

Preferential Expression of Alternatively Spliced mRNAs Encoding Type II Procollagen with a Cysteine-Rich Amino-Propeptide in Differentiating Cartilage and Nonchondrogenic Tissues during Early Mouse Development

1993 • 128 citations

The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo

1999 • 123 citations

Interpretation of a BMP Activity Gradient in Drosophila Embryos Depends on Synergistic Signaling by Two Type I Receptors, SAX and TKV

1998 • 122 citations

Spatially Restricted Activation of the SAX Receptor by SCW Modulates DPP/TKV Signaling in Drosophila Dorsal–Ventral Patterning

1998 • 103 citations

Bone Morphogenetic Protein-1 Processes the NH2-terminal Propeptide, and a Furin-like Proprotein Convertase Processes the COOH-terminal Propeptide of pro-α1(V) Collagen

1998 • 95 citations

New gene, nel, encoding a M_r 93 K protein with EGF‐like repeats is strongly expressed in neural tissues of early stage chick embryos

1995 • 85 citations

Expression of two nonallelic type II procollagen genes during Xenopus laevis embryogenesis is characterized by stage-specific production of alternatively spliced transcripts.

1991 • 78 citations

The Mr 24,000 phosphoprotein from developing bone is the NH2-terminal propeptide of the alpha 1 chain of type I collagen.

1987 • 78 citations

BMP1-Related Metalloproteinases Promote the Development of Ventral Mesoderm in Early Xenopus Embryos

1998 • 66 citations

short gastrulation, a mutation causing delays in stage-specific cell shape changes during gastrulation in Drosophila melanogaster

1988 • 65 citations

Overexpression of the Homeobox GeneXnot-2Leads to Notochord Formation inXenopus

1996 • 49 citations

Reorganizing the Organizer 75 Years On

1999 • 38 citations

Coding Sequence and Expression Patterns of Mouse Chordin and Mapping of the Cognate MouseChrdand HumanCHRDGenes

1998 • 33 citations

A unity of opposites

1999 • 10 citations

Community split on Peronist reform effort

1999 • 9 citations